scholarly journals A unique case of medulla oblongata epidermoid cyst

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Tran Anh Tuan ◽  
Nguyen Minh Duc

Abstract Epidermoid cysts (ECs) are slow-growing, benign tumors that represent <2% of all intracranial tumors. ECs can be divided into following two types: extra-axial and intra-axial. Extra-axial ECs are most often positioned in the cerebellopontine angle. Intra-axial ECs, which are also referred to as intraparenchymal ECs, are most commonly found in supratentorial structures, such as the frontal and temporal lobes, accounting for <2% of all intracranial ECs and are especially rare in children. In this report, we described a unique case of medulla oblongata EC in a child, to contribute this knowledge to the existing body of literature.

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Fayçal Lakhdar ◽  
El Mehdi Hakkou ◽  
Rachid Gana ◽  
Rachid My Maaqili ◽  
Fouad Bellakhdar

Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.


2019 ◽  
Vol 38 (03) ◽  
pp. 210-214
Author(s):  
Eduardo Cambruzzi ◽  
Nelson Pires Ferreira ◽  
Gabriel Barcellos ◽  
Pablo Fruet

AbstractEpidermoid cysts (ECs) of the central nervous system (CNS) constitute benign circumscribed lesions that are more common in lateral than in midline sites. Epidermoid cysts of the CNS arise more frequently in the cerebellopontine angle, around the pons, near the sella, within the temporal lobe, in the diploe, and in the spinal canal. Most common tumoral lesion of sellar region is pituitary adenoma, and sellar cystic epithelial masses may be difficult to differentiate based only on clinical and imaging findings. Epidermoid cysts are covered by keratinized squamous epithelium and are usually filled with keratin lamellae. The process is, for the most part, maldevelopmental in origin, presumably arising from trapped surface ectodermal elements in association with the developing CNS during the closure of the neural groove or formation of the secondary cerebral vesicles. In the present study, the authors describe a case of sellar epidermoid cyst producing endocrine alterations and visual disturbance in a 35 years woman, and review the physiopathological and diagnostic criteria of this lesion.


2019 ◽  
Vol 10 (02) ◽  
pp. 352-354 ◽  
Author(s):  
Siddartha Reddy Musali ◽  
Imran Mohammed ◽  
Prakash Rao Gollapudi ◽  
Sai Kumar Maley

ABSTRACTEpidermoid cysts are commonly seen intracranial lesions but their occurrence in the spine is rare. They account for <1% of all the benign tumors of the spine. These are benign epithelial-lined cysts filled with keratin. They are classified into two types: congenital or acquired. Congenital epidermoid cysts are more commonly associated with spinal dysraphic states such as syringomyelia, dermal sinus and spina bifida whereas the acquired cysts are associated with repeated lumbar punctures. Based on the location, they can be extradural, intradural, extramedullary, or intramedullary. Most of the epidermoids are intradural extramedullary. Intramedullary epidermoid cysts are very uncommon. We report a case of a 6-year-old female patient with dorsal epidermoid cyst with neurological deficits. Magnetic resonance imaging of the spine showed a well-defined lesion from D9 to D12 which was hypointense on T1W1 and heterogeneously hyperintense on T2W2. Surgery was performed to excise the lesion and to decompress the spinal cord. Histopathological examination of the excised lesion confirmed it as an epidermoid cyst.


2019 ◽  
Vol 08 (03) ◽  
pp. 191-192
Author(s):  
Sushil Kumar ◽  
Sandeep Sharma ◽  
Rajneesh Misra ◽  
Kundan Kumar

AbstractEpidermoid cysts of the fourth ventricle are slow-growing benign rare lesions. We report a case of fourth ventricle epidermoid in a young lady with short duration of symptoms.


1992 ◽  
Vol 76 (3) ◽  
pp. 528-533 ◽  
Author(s):  
Alain Roux ◽  
Claude Mercier ◽  
Albert Larbrisseau ◽  
Louis-Jacques Dube ◽  
Céline Dupuis ◽  
...  

✓ Epidermoid cysts are tumors familiar to neurosurgeons, but intramedullary epidermoid cysts are rare. The authors report the case of a 6-year-old girl presenting with progressive paraparesis. A midthoracic intramedullary mass was revealed on myelography and magnetic resonance (MR) imaging and confirmed as an intramedullary epidermoid cyst at surgery, at which time the cyst was removed. This is the fourth report documenting a purely intramedullary epidermoid cyst occurring in a child. The pathology and etiology, epidemiology, clinical features, radiology (including MR image characteristics), and surgical treatment of such rare intramedullary benign tumors are discussed. Magnetic resonance imaging reduces the delay in diagnosis of spinal cord tumors but should be guided by clinical judgment.


1982 ◽  
Vol 19 (6) ◽  
pp. 646-650 ◽  
Author(s):  
J. N. Kornegay ◽  
E. J. Gorgacz

Intracranial epidermoid cysts were identified within the fourth ventricle of three dogs. The cysts measured up to 2.5 cm in diameter, were lined by stratified squamous epithelium, and contained intraluminal keratinaceous debris. Secondary compression of the medulla oblongata and cerebellum caused neurologic dysfunction in two dogs; the cyst was an incidental finding in the other dog. Similarities between these dogs and three previously reported intracranial epidermoid cysts in dogs included an apparent predilection for young dogs and involvement of the cerebellopontine angle, fourth ventricle, or both.


2017 ◽  
Vol 16 (04) ◽  
pp. 232-235
Author(s):  
Pramod Giri ◽  
Kirti Jaiswal ◽  
Milind Bhatkule ◽  
Vaibhav Chavan

AbstractAn epidermoid cyst is a rare intracranial neoplasm. It is mostly found in cerebellopontine angle, suprasellar region, interhemispheric fissure, and is rarely found in other locations too. Epidermoid cyst at the parietooccipital area is rare, and calcification among epidermoids is very unusual and dystrophic in nature. The clinical presentation is usually in adults because of slow-growing nature of epidermoid cyst. Here, we present the case of a 5-year-old child with intellectual disability who presented with seizure and frequent crying episodes and was diagnosed with an intradural extra-axial calcified mass of size 8 × 5.5 × 5 cm in the right parietooccipital region which turned out to be a calcified epidermoid cyst and was excised successfully in toto. This is the youngest reported case of the calcified epidermoid cyst at an unusual site of our knowledge.


2011 ◽  
Vol 1 ◽  
pp. 4 ◽  
Author(s):  
Norman Loberant ◽  
Shweta Bhatt ◽  
Edward Messing ◽  
Vikram S. Dogra

Testicular epidermoid cysts are the most common benign tumors of the testes, but account for only 1-2% of all testicular tumors. In a young man presenting with a testicular mass, a high index of suspicion must be maintained for the malignant testicular germ cell tumor, which is 50-times more common than testicular epidermoid cyst. Bilateral testicular epidermoid cysts are a very rare condition, with only a few reports in the literature. It is extremely important in this condition to make a correct pre-operative diagnosis on imaging to enable a testis-sparing surgery.


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Eric K. C. Law ◽  
Ryan K. L. Lee ◽  
Alex W. H. Ng ◽  
Deyond Y. W. Siu ◽  
Ho-Keung Ng

Epidermoid cysts are benign slow growing extra-axial tumours that insinuate between brain structures, while their occurrences in intra-axial or intradiploic locations are exceptionally rare. We present the clinical, imaging, and pathological findings in two patients with atypical epidermoid cysts. CT and MRI findings for the first case revealed an intraparenchymal epidermoid cyst that demonstrated no restricted diffusion. The second case demonstrated an aggressive epidermoid cyst that invaded into the intradiploic spaces, transverse sinus, and the calvarium. The timing of ectodermal tissue sequestration during fetal development may account for the occurrence of atypical epidermoid cysts.


Author(s):  
Robert Sinurat ◽  
Fajar Lamhot Gultom

Background<br />Tumors of the skull usually affect adult patients and less than twenty percent of pediatric patients. As the tumors grow, the surrounding bone may undergo destruction and erosion. When the tumors are located in the fontanel, the timely closure of the fontanel may be inhibited. Epidermoid cysts are benign tumors that are intracranially located and very rarely in the midline of the cranium. Meanwhile about 32% of stratified-squamous epithelial epidermoid cysts affect the head and neck region and only 6.7% occur in the scalp. We report an unusual epidermoid cyst located and growing in the anterior fontanel of a pediatric patient and inhibiting fontanel closure.<br /><br />Case Description <br />A 21-month-old boy and his parents visited our polyclinic because there was a lump on his anterior fontanel since four months before they came to the hospital. The lump was initially the size of a peanut and had grown to become as large as a quail’s egg. The physical examination was normal and the brain CT-scan showed bone destruction without any intracranial lesion. The tumor was excised on the preoperative diagnosis of dermoid cyst. Histopathology examination showed the characteristics of an epidermoid cyst. The cyst had a wall and was full of keratin flakes without hair follicles or sebaceous glands. Follow-up one year after complete excision did not reveal any recurrence. <br /><br />Conclusion<br />Epidermoid cysts in the skull of pediatric patients must be completely excised as soon as possible because their growth can damage the bone and inhibit the closure of the sutures.


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