scholarly journals Atypical Intracranial Epidermoid Cysts: Rare Anomalies with Unique Radiological Features

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Eric K. C. Law ◽  
Ryan K. L. Lee ◽  
Alex W. H. Ng ◽  
Deyond Y. W. Siu ◽  
Ho-Keung Ng

Epidermoid cysts are benign slow growing extra-axial tumours that insinuate between brain structures, while their occurrences in intra-axial or intradiploic locations are exceptionally rare. We present the clinical, imaging, and pathological findings in two patients with atypical epidermoid cysts. CT and MRI findings for the first case revealed an intraparenchymal epidermoid cyst that demonstrated no restricted diffusion. The second case demonstrated an aggressive epidermoid cyst that invaded into the intradiploic spaces, transverse sinus, and the calvarium. The timing of ectodermal tissue sequestration during fetal development may account for the occurrence of atypical epidermoid cysts.

2016 ◽  
Vol 30 (3) ◽  
pp. 461-466
Author(s):  
Vivek Kumar Kankane ◽  
Gaurav Jaiswal ◽  
Tarun Kumar Gupta

Abstract Epidermoid cysts are benign slow growing more often extra-axial tumors that insinuate between brain structures, we present the clinical, imaging, and pathological findings in 35 years old female patients with atypical epidermoid cysts which was situated anterior, middle & posterior cranial fossa. NCCT head revealed hypodense lesion over right temporal and perisylvian region with extension in prepontine cistern with mass effect & midline shift and MRI findings revealed a non-enhancing heterogeneous signal intensity cystic lesion in right frontal & temporal region extending into prepontine cistern with restricted diffusion. Patient was detoriated in night of same day of admission, emergency Fronto-temporal craniotomy with anterior peterousectomy and subtotal resection was done. The histological examination confirms the epidermoid cyst. The timing of ectodermal tissue sequestration during fetal development may account for the occurrence of atypical epidermoid cysts.


2019 ◽  
Vol 08 (03) ◽  
pp. 191-192
Author(s):  
Sushil Kumar ◽  
Sandeep Sharma ◽  
Rajneesh Misra ◽  
Kundan Kumar

AbstractEpidermoid cysts of the fourth ventricle are slow-growing benign rare lesions. We report a case of fourth ventricle epidermoid in a young lady with short duration of symptoms.


Author(s):  
Roxana Dumitriu ◽  
Roxana Dușceac ◽  
Anda Dumitrașcu ◽  
Cătălina Poiană

Abstract Background Epidermoid cysts are very rare benign lesions of epithelial origin, slow growing extra-axial tumours and they accord for 1% of all intracranial tumours. They frequently occur at the cerebellopontine angle and parasellar regions insinuating brain structures. They are often associated with a high rate of residual tumor and recurrence. Clinical Case We present the case of a 18 year old patient who was admitted in the our clinic for secondary amenorrhea. The CT scan showed a large median mass with a mixed structure (calcareous and cystic) resembling a craniopharyngioma. Preoperatively the hormonal profile showed deficiency of all anterior pituitary hormones. Transsphenoidal surgery was performed and the histopathological exam established the diagnosis of sellar epidermoid cyst with parasellar extension. Postoperatively the patient developed iatrogenic Cushing syndrome (due to large amounts of dexamethasone given) and diabetes insipidus. Conclusion Epidermoid cysts are challenging tumours because of the extension along the subarachnoid spaces around delicate neurovascular structures therefore they are difficult to be completely resected. The particularity of this case stands in the rare occurrence of this types of tumours and the fact that although in these patients with hypopituitarism diabetes insipidus is present primarily our patient developed postoperatively.


2020 ◽  
pp. 1-2
Author(s):  
Shashikant Raghunath Mane

Background: - Epidermoid tumors are benign slow-growing tumors that usually manifest as insinuating masses. MRI evaluation is most sensitive radiological modality available in evaluation & characterization of intracranial epidermoid tumors. It can be accurately differentiated from arachnoid cyst from various characteristic features on MRI. However, post operative histopathology is the gold standard for diagnosis as well as confirmation of MRI findings. Conclusion: - Epidermoid tumors can be accurately diagnosed with MR imaging with our study showing around 91% sensitivity and 75% specificity, positive predictive value 95% and negative predictive value 60%.


2014 ◽  
Vol 4 (1) ◽  
pp. 67-70 ◽  
Author(s):  
P Devani ◽  
Hira Lal ◽  
A Thakral

The purpose of this report is to present radiological features of a rare entity called Parry-Romberg syndrome (also known as Progressive hemifacial atrophy). The authors report one rare case of a 18 year old female patient with Parry-Romberg syndrome, accompanied by a brief review of literature and various radiological features of this entity. Final diagnosis of a Parry-Romberg syndrome was made on clinical and radiological grounds. Radiologists should be familiar with various radiographic, CT and MRI findings observed in this disorder. DOI: http://dx.doi.org/10.3126/njr.v4i1.11571 Nepalese Journal of Radiology, Vol.4(1) 2014: 67-70


2012 ◽  
Vol 116 (3) ◽  
pp. 611-621 ◽  
Author(s):  
Xiaohui Ren ◽  
Song Lin ◽  
Zhongcheng Wang ◽  
Lin Luo ◽  
Zhongli Jiang ◽  
...  

Object Most intracranial epidermoid cysts typically present with long T1 and T2 signals on MR images. Other epidermoid cysts with atypical MR images are often misdiagnosed as other diseases. In this study the authors aimed to analyze the incidence and the clinical, radiological, and pathological features of atypical epidermoid cysts. Methods Among 428 cases of intracranial epidermoid cysts that were surgically treated between 2002 and 2008 at Beijing Tiantan Hospital, cases with an atypical MR imaging appearance were chosen for analysis. Clinical and pathological parameters were recorded and compared in patients with lesions demonstrating typical and atypical MR appearance. Results An atypical epidermoid cyst accounts for 5.6% of the whole series. Radiologically, 58.3% of atypical epidermoids were misdiagnosed as other diseases. Compared with a typical epidermoid cyst, atypical epidermoid lesions were significantly larger (p = 0.016, chi-square test). Pathologically, hemorrhage was found in 21 patients with atypical epidermoid cyst and is significantly correlated with granulation (p = 0.010, Fisher exact test). Old hemorrhage was found in 13 cases and was significantly correlated with cholesterol crystals. Twenty-one patients were followed up for 1.3–8.6 years after surgery. The 5- and 8-year survival rates were both 100%. Three patients experienced cyst recurrence. The 5- and 8-year recurrence-free rates were 95% and 81.4%, respectively. Conclusions Radiologically, an atypical epidermoid cyst should be differentiated from dermoid cyst, teratoma, schwannoma, glioma, craniopharyngioma, and cavernous angioma. A tendency toward spontaneous hemorrhage is confirmed in atypical epidermoid cysts, and a hypothesis was proposed for spontaneously intracystic hemorrhage in atypical epidermoid cysts. Follow-up confirmed long-term survival of patients with atypical epidermoid cysts.


2013 ◽  
Vol 7 (3-4) ◽  
pp. e244-7 ◽  
Author(s):  
Hasan Salih Sağlam ◽  
Şükrü Kumsar ◽  
Osman Köse ◽  
Oztuğ Adsan

A 46-year old man was admitted with a scrotal long standing painless mass. The work up included physical examination, alpha- fetoprotein (αFP) and beta-human chorionic gonadotropin (β-hCG) analyses, scrotal ultrasound (US), magnetic resonance imaging (MRI) and urethrocystoscopy. The patient underwent surgery. Surgical exploration revealed a separate mass between the testes extending superiorly with a thin stalk.  It was dissected easily to the anterior aspect of the seminal vesicles and removed from the junction to the seminal vesicles. Pathology reported an epidermoid cyst. To our knowledge this is the first case of a scrotal extratesticular epidermoid cyst attached to the seminal vesicles. Epidermoid cysts can be seen anywhere in the midline from the cranium to the anus.   Embriologically   abnormal closure of neural groove or epithelial fusion lines is one of the theories that seem more probable. Genital epidermoid cysts are rare, painless and usually located in the testes.  Up to date less than 10   case reports of extratesticular epidermoid cysts have been published.  For those cases malignancy may not be ruled out, so the surgical removal was advocated.


2019 ◽  
Vol 80 (S 03) ◽  
pp. S325-S326
Author(s):  
Marcus Vinicius de Morais ◽  
Romulo Almino de Alencar Arrais Mota ◽  
Thais Aparecida Marques ◽  
Rafael Duarte de Souza Loduca ◽  
Paulo Mácio de Porto Melo

Objectives To describe the operative technique for treatment of epidermoid cysts in the cerebellopontine angle (CPA). Design The present video is a case report. Setting Patient is positioned in three-quarters prone. Retrosigmoid approach should be made under neurological monitoring and with neuronavegation to help achieve maximal safe resection. The skin incision is vertical, slightly curved, 5 mm medial to the mastoid notch. Craniectomy is superiorly limited by the transverse sinus and laterally limited by the sigmoid sinus. A C-shaped durotomy is made with its base protecting the sigmoid sinus. The lesion is removed in piecemeal fashion (Fig. 1). The neurological monitoring helps. Results The patient was discharged 2 days later without neurological deficits. Conclusions The surgical treatment associated with neurological monitoring and neuronavegation is a safe procedure to treat epidermoid cysts in the CPA.The link to the video can be found at: https://youtu.be/sEuFyq9c2sw.


2021 ◽  
Vol 82 (01) ◽  
pp. e6-e10
Author(s):  
Ján Kozák ◽  
Jozef Šurkala ◽  
Martin Novotný ◽  
Marián Švajdler

AbstractIntracranial epidermoid cysts are slow growing congenital avascular neoplasms that spread across the basal surface of the brain. They most commonly occur in the paramedial region in the cerebellopontine angle and the parasellar region. Despite its generally benign nature, sporadically they can be accompanied with hemorrhage or very rarely undergo malignant transformation. The authors present a case report of a patient with a hemorrhagic vermian epidermoid cyst and a review of all published similar cases.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Fayçal Lakhdar ◽  
El Mehdi Hakkou ◽  
Rachid Gana ◽  
Rachid My Maaqili ◽  
Fouad Bellakhdar

Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.


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