On the Right Tract

2018 ◽  
pp. 109-112
Author(s):  
Aaron E. Miller ◽  
Tracy M. DeAngelis ◽  
Michelle Fabian ◽  
Ilana Katz Sand
Keyword(s):  
Peripheral Neuropathy ◽  
Early Detection ◽  
Cerebellar Ataxia ◽  
Therapeutic Approach ◽  
Clinical Suspicion ◽  
Variable Response ◽  
Neurological Syndrome ◽  
Underlying Malignancy ◽  
Mediator Protein ◽  
The Right

Paraneoplastic myelopathies are uncommon, but maintenance of a high index of clinical suspicion is critical, as the neurological syndrome often predates discovery of an underlying malignancy and can facilitate early detection and potentially improve prognosis. Most paraneoplastic myelopathies are associated with additional neurological symptomatology, such as encephalitis, peripheral neuropathy, or cerebellar ataxia, due to the specific, respective auto-antibodies involved. Anti-Hu antibody, identified in our patient, appears to be the most common antibody, followed by amphiphysin, and collapsing response mediator protein 5, among others. The therapeutic approach to patients with paraneoplastic myelopathies focuses primarily on treatment of the underlying cancer and, thereafter, subsequent trials of immunotherapies, which have demonstrated variable response.

scholarly journals A Comparison of Screening Tools for the Early Detection of Peripheral Neuropathy in Adults with and without Type 2 Diabetes

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Jennifer J. Brown ◽  
Shana L. Pribesh ◽  
Kimberly G. Baskette ◽  
Aaron I. Vinik ◽  
Sheri R. Colberg
Keyword(s):  
Type 2 Diabetes ◽  
Peripheral Neuropathy ◽  
Early Detection ◽  
Sural Nerve ◽  
Tuning Fork ◽  
Low Cost ◽  
Screening Tools ◽  
The Right ◽  
Design And Methods

Objective. Examine the effectiveness of the 128 Hz tuning fork, two monofilaments, and Norfolk Quality of Life Diabetic Neuropathy (QOL-DN) questionnaire as tools for the early detection of diabetic peripheral neuropathy (DPN) in overweight, obese, and inactive (OOI) adults or those who have prediabetes (PD) or type 2 diabetes (T2D). Research Design and Methods. Thirty-four adults (mean age 58.4 years ± 12.1) were divided by glycemia (10 OOI normoglycemic, 13 PD, and 11 T2D). Sural nerves were tested bilaterally with the NC-stat DPNCheck to determine sural nerve amplitude potential (SNAP) and sural nerve conduction velocity (SNCV). All other testing results were compared to SNAP and SNCV. Results. Total 1 g monofilament scores significantly correlated with SNAP values and yielded the highest sensitivity and specificity combinations of tested measures. Total QOL-DN scores negatively correlated with SNAP values, as did QOL-DN symptoms. QOL-DN activities of daily living correlated with the right SNAP, and the QOL-DN small fiber subscore correlated with SNCV. Conclusions. The 1 g monofilament and total QOL-DN are effective, low-cost tools for the early detection of DPN in OOI, PD, and T2D adults. The 128 Hz tuning fork and 10 g monofilament may assist DPN screening as a tandem, but not primary, early DPN detection screening tools.

scholarly journals Cardiac Aspergilloma: A Rare Case of a Cardiac Mass Involving the Native Tricuspid Valve, Right Atrium, and Right Ventricle in an Immunocompromised Patient

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Christina S. Chen-Milhone ◽  
Kalyan Chakravarthy Potu ◽  
Sudhir Mungee
Keyword(s):  
Tricuspid Valve ◽  
Right Atrium ◽  
Rare Case ◽  
Opportunistic Infections ◽  
Immunocompromised Patient ◽  
Clinical Suspicion ◽  
Ventricular Rate ◽  
Immunocompromised Patients ◽  
Transthoracic Echocardiogram ◽  
The Right

Aspergillus can cause devastating opportunistic infections in immunocompromised patients. Rarely does this fungus invade the heart, and when it does, survival is especially poor despite optimal medical and surgical treatment. We report a case of cardiac aspergilloma with involvement of the tricuspid valve and both the right atrium and ventricle found on a transthoracic echocardiogram in an immunocompromised patient after developing atrial fibrillation with rapid ventricular rate. The findings from this case suggest that early clinical suspicion is critical in early diagnosis and thus early treatment.

scholarly journals Type 4 appendiceal diverticulum within a de Garengeot hernia

2016 ◽  
Vol 98 (7) ◽  
pp. e141-e142 ◽  
Author(s):  
SH Rossi ◽  
E Coveney
Keyword(s):  
Femoral Hernia ◽  
Cystic Lesion ◽  
Vermiform Appendix ◽  
Clinical Suspicion ◽  
Intraluminal Pressure ◽  
Rare Entity ◽  
History Of ◽  
The Right ◽  
De Garengeot Hernia ◽  
Learning Points

A de Garengeot hernia is defined as an incarcerated femoral hernia containing the vermiform appendix. We describe the case of a patient with a type 4 appendiceal diverticulum within a de Garengeot hernia and delineate valuable learning points.A 76-year-old woman presented with a 2-week history of a non-reducible painless femoral mass. Outpatient ultrasonography demonstrated a 36mm × 20mm smooth walled, multiloculated, partially cystic lesion anterior to the right inguinal ligament in keeping with an incarcerated femoral hernia. Intraoperatively, the appendix was found to be incarcerated in the sac of the femoral hernia and appendicectomy was performed. Histopathology demonstrated no evidence of inflammation in the appendix. However, an incidental appendiceal diverticulum was identified.It is widely recognised that a de Garengeot hernia may present with concomitant appendicitis, secondary to raised intraluminal pressure in the incarcerated appendix. Appendiceal diverticulosis is also believed to develop in response to raised pressure in the appendix and may therefore develop secondary to incarceration in a de Garengeot hernia. To our knowledge, only one such case has been described in the literature. A de Garengeot hernia is a rare entity, which poses significant diagnostic challenges. A high index of clinical suspicion is necessary as these hernias are at particularly high risk of perforation and so prompt surgical management is paramount.

scholarly journals Melioidosis in Bihar, India: unearthing the first of many?

2021 ◽  
Vol 3 (9) ◽  
Author(s):  
Isra Halim ◽  
Prathyusha Kokkayil ◽  
Ravi Kirti ◽  
Rajeev Nayan Priyadarshi ◽  
Asim Sarfraz ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Clinical Suspicion ◽  
Radiological Features ◽  
First Case ◽  
Insidious Onset ◽  
Ankle Joints ◽  
The World ◽  
Resource Poor ◽  
Empirical Antibiotics ◽  
The Right

Melioidosis, a disease with protean clinical manifestations, is prevalent in many parts of India, with established endemic hotspots on the southern coast of the country. However, it is still underdiagnosed in many resource-poor regions of the country. We report what is, to the best of our knowledge, the first case of melioidosis diagnosed and treated in Bihar, an economically underdeveloped state in East India. The patient, a 52-year-old diabetic male, presented to the outpatient department with a fever of insidious onset along with pain and restriction of movement in the right shoulder joint and right knee joint, and swelling and tenderness of bilateral ankle joints. Radiological features were suggestive of multiple joint and organ abscesses. A diagnosis of disseminated septicaemic melioidosis was confirmed microbiologically. The patient improved clinically following aggressive treatment with meropenem and cotrimoxazole. The case highlights the need for increased clinical suspicion of melioidosis and adequate diagnostic facilities, as well as the need for early institution of appropriate empirical antibiotics in suspected cases of melioidosis in this region of the world.

scholarly journals Radiological CT findings and time evolution in acute stroke: case report

2021 ◽  
Vol 8 (2) ◽  
pp. 76-79
Author(s):  
Laio Bastos de Paiva Raspante ◽  
Laura Filgueiras Mourão Ramos ◽  
Uedson Tazinaffo
Keyword(s):  
Artificial Intelligence ◽  
Case Report ◽  
Emergency Room ◽  
Acute Stroke ◽  
Cerebral Perfusion ◽  
Imaging Finding ◽  
Clinical Suspicion ◽  
Perfusion Study ◽  
The Right ◽  
Optimized Treatment

Case report of a 95-year-old female patient that was admitted to the emergency room with a sudden weakness on the right who underwent propaedeutic imaging with cerebral perfusion study by CT using artificial intelligence (AI) software for clinical suspicion of acute stroke. The case illustrates a frequent and specific imaging finding for stroke and its disappearance in the control exam even without optimized treatment.

scholarly journals Adult gonococcal keratoconjunctivitis: early detection is key

2020 ◽  
Vol 17 (1) ◽  
pp. 30-34
Author(s):  
Daniel Lai ◽  
Keith Ong
Keyword(s):  
Polymerase Chain Reaction ◽  
Early Detection ◽  
Neisseria Gonorrhoeae ◽  
Ophthalmic Solution ◽  
Careful Monitoring ◽  
Corneal Ulceration ◽  
Chain Reaction ◽  
Bacterial Conjunctivitis ◽  
Polymerase Chain ◽  
The Right

We describe a case of a 52-year-old male presenting with severe mucopurulent conjunctivitis of the right eye. Corneal ulceration and associated anterior chamber activity was noted later in the course of the disease. Neisseria gonorrhoeae was positive on polymerase chain reaction (PCR) testing earlier than traditional microscopy and culture. He was successfully treated with ceftriaxone 500 mg intravenously and azithromycin 1 g orally as single doses in addition to ofloxacin ophthalmic solution 0.3% hourly to the right eye. This case highlights the need to consider the possibility of gonococcus in cases of suspected bacterial conjunctivitis, careful monitoring for corneal involvement and the importance of early detection with PCR.

scholarly journals MRI-Based Normative Measurement of the Ocular Globe Position in Relation to Inter-Zygomatic Line among Nepalese Subjects

2021 ◽  
Vol 8 (8) ◽  
Author(s):  
Raj JB ◽  
Keyword(s):  
Early Detection ◽  
Posterior Margin ◽  
Anterior Margin ◽  
Systemic Diseases ◽  
Major Consequence ◽  
Imaging Parameter ◽  
Tertiary Center ◽  
Significant Difference ◽  
The Right ◽  
Gender Groups

Introduction: Proptosis and enophthalmos are cardinal signs of many orbito-ocular and systemic diseases. The need for an imaging parameter that will aid its early detection is necessary, as visual compromise is a major consequence if they are not diagnosed and managed early. Methodology: This prospective study was performed in a tertiary center. Data were collected over the period of January to April 2021 with total of 300 normal ocular globes. The measurement was done at the level of lens (midglobe section) on T2-weighted axial image. Results: The distance between the anterior margin and inter zygomatic line of the right ocular globe was 16.95 ± 1.48 mm (ranged 14.2 - 20.5 mm) and that of left was 16.86 ± 1.38 mm (ranged 14.2 - 20.3 mm). The position of the globes showed no statistically significant differences among gender groups in our study and the position of the right globe within the orbit was significantly different from that of the left orbit. Conclusion: The position of the globes showed higher values in males than in female. However, a statistically significant difference in globe position was observed between right and left orbits. The distance between the posterior margin of the globe and the inter zygomatic line was found to be lower among the Nepalese population compared with other population.

scholarly journals Analytical Review of Major Nocturnal Pests’ Detection Technique using Computer Vision

2018 ◽  
Vol 11 (3) ◽  
pp. 179-182
Author(s):  
Deven J. Patel ◽  
Nirav Bhatt
Keyword(s):  
Computer Vision ◽  
Early Detection ◽  
Review Article ◽  
Pink Bollworm ◽  
Detection Technique ◽  
Future Research ◽  
White Grub ◽  
Analytical Review ◽  
Pest Detection ◽  
The Right

Research in agriculture is increasing quality and quantity, but pest reduces it. To prevent the effect of these pests, insecticides are used. But excessive use of pesticides is very harmful to production and environment. So initially pest detection is necessary. We work on nocturnal pests because that can be easily attracting using night trapping tools. The purpose of this review article is to analyse the popular techniques and find the right technique for the initial diagnosis and early detection of major nocturnal flying pests like Pink Bollworm, White Grub, Helicoverpa and Spodoptera. The importance of early detection can be in identifying and classifying the pests in a digital view. We have concluded our results with the various methods and the prospects of future research.

scholarly journals The use of infrared thermography for welfare assessment during the application of ear tags to lambs

2017 ◽  
Vol 60 (3) ◽  
pp. 297-302 ◽  
Author(s):  
Murat Karakuş ◽  
Ferda Karakuş
Keyword(s):  
Early Detection ◽  
Infrared Thermography ◽  
Behavioral Responses ◽  
Infrared Images ◽  
Thermal Camera ◽  
Inflammatory Reactions ◽  
Welfare Assessment ◽  
The Mean ◽  
The Right

Abstract. The aim of this study was to determine the effect of metal-tipped, plastic-tipped, and electronic ear tags on the likelihood of infection using infrared thermography and to evaluate the effect on welfare by examining the behavioral responses of the lambs. Ninety lambs with an average age of 6 months were used in this study. Before the application of the ear tags, infrared images of the right and left ears of the lambs were taken with the thermal camera and the infrared temperatures were recorded. Measurements were repeated on days 1, 4, 10, and 30 after the ear tag application. The mean of infrared ear temperatures on days 0, 1, 4, 10, and 30 were found to be 14.60, 23.20, 23.77, 20.36, and 17.61 °C for the metal-tipped ear tag group; 15.69, 21.50, 20.42, 18.00, and 16.39 °C for the plastic-tipped ear tag group; and 15.17, 29.47, 27.49, 25.93, and 20.61 °C for the electronic ear tag group. The infrared temperatures on days 1, 4, and 10 in the control and experimental groups were significantly different from each other (P < 0.001). The plastic-tipped ear tags caused fewer problems and are preferred to the traditional ear tags with metal tips. The electronic ear tags caused more inflammatory reactions compared to metal- or plastic-tipped ear tags. The infrared thermography method may be used as a useful tool in the early detection of the inflammatory reactions and infections caused by the application of ear tags.

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