scholarly journals Longitudinal Association Between Smoking Abstinence and Depression Severity in Those With Baseline Current, Past, and No History of Major Depressive Episode in an International Online Tobacco Cessation Study

2020 ◽  
Author(s):  
Nancy H Liu ◽  
Chaorong Wu ◽  
Eliseo J Pérez-Stable ◽  
Ricardo F Muñoz
Keyword(s):  
Depressive Symptoms ◽  
Depressive Episode ◽  
Tobacco Cessation ◽  
Major Depressive Episode ◽  
Smoking Abstinence ◽  
Time Varying ◽  
Depression Severity ◽  
Major Depressive ◽  
History Of ◽  
Over Time

Abstract Introduction We use multilevel modeling to parse out the effects of time-varying smoking abstinence and baseline depression (history and severity) on depression severity over 1 year. Aims and Methods Participants were 1000 smokers recruited worldwide for an online randomized controlled tobacco cessation trial. We examined whether changes in depression severity over time were associated with self-reported 7-day point prevalence smoking status assessed at 1-, 3-, 6-, and 12-month follow-up (FU) using baseline major depressive episode (MDE) history and baseline depression severity as time-invariant covariates. We present depression severity means and smoking abstinence at each FU. Results Regardless of concurrent abstinence status, baseline MDE history was significantly related to depression severity over time: those reporting a past MDE had worse depressive symptoms over time compared with those reporting no MDE history. Baseline depression severity interacted significantly with time-varying abstinence status: for every 1-unit increase in baseline scores on the Center for Epidemiological Studies—Depression Scale (CES-D), individuals who were smoking at FU reported CES-D scores that were 0.17 points higher than those who were abstinent. In this context, nicotine dependence, gender, age, or marital status did not affect depression severity. Conclusions In the context of cessation, having an MDE history plays a significant role in the trajectory of depression severity over the course of 1 year, regardless of abstinence status. Abstinence is related to lower depressive symptoms at each FU, and this effect was stronger at higher levels of baseline depression severity. Implications This study indicates that depressive symptoms are not exacerbated among individuals who are quitting smoking at 1-, 3-, 6-, and 12-month FUs. Depression severity is worse with a baseline history of MDE. Further, those with high baseline depression severity who continue smoking have worse depressive symptoms throughout a 1-year period compared with their abstinent counterparts.

scholarly journals Importance of retardation and fatigue/interest domains for the diagnosis of major depressive episode after stroke: a four months prospective study

2009 ◽  
Vol 31 (3) ◽  
pp. 202-207 ◽  
Author(s):  
Luisa de Marillac Niro Terroni ◽  
Renério Fráguas ◽  
Mara de Lucia ◽  
Gisela Tinone ◽  
Patricia Mattos ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Rating Scale ◽  
University Hospital ◽  
Regression Equations ◽  
Stroke Patients ◽  
Major Depressive ◽  
Post Stroke ◽  
Neurology Clinic

OBJECTIVE: Post-stroke major depressive episode is very frequent, but underdiagnosed. Researchers have investigated major depressive episode symptomatology, which may increase its detection. This study was developed to identify the depressive symptoms that better differentiate post-stroke patients with major depressive episode from those without major depressive episode. METHOD: We screened 260 consecutive ischemic stroke patients admitted to the neurology clinic of a university hospital. Seventy-three patients were eligible and prospectively evaluated. We assessed the diagnosis of major depressive episode using the Structured Clinical Interview for DSM-IV and the profile of depressive symptoms using the 31-item version of the Hamilton Depression Rating Scale. For data analysis we used cluster analyses and logistic regression equations. RESULTS: Twenty-one (28.8%) patients had a major depressive episode. The odds ratio of being diagnosed with major depressive episode was 3.86; (95% CI, 1.23-12.04) for an increase of one unit in the cluster composed by the domains of fatigue/interest and retardation, and 2.39 (95% CI, 1.21-4.71) for an increase of one unit in the cluster composed by the domains of cognitive, accessory and anxiety symptoms. The domains of eating/weight and insomnia did not contribute for the major depressive episode diagnosis. CONCLUSION: The domains of retardation and interest/fatigue are the most relevant for the diagnosis of major depressive episode after stroke.

scholarly journals Severity of Depressive Symptoms is Associated with Venous Thromboembolism in Hospitalized Patients with a Major Depressive Episode

2021 ◽  
Vol Volume 17 ◽  
pp. 2955-2963
Author(s):  
Kazuhisa Yoshizawa ◽  
Masahiro Takeshima ◽  
Sayaka Ishino ◽  
Masaya Ogasawara ◽  
Dai Fujiwara ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Venous Thromboembolism ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Hospitalized Patients ◽  
Major Depressive

scholarly journals Association between Depression and Renal Hyperfiltration in a General Chinese Population

2019 ◽  
Vol 44 (6) ◽  
pp. 1441-1452
Author(s):  
Miao Lin ◽  
Huibin Huang ◽  
Jin Yao ◽  
Jixing Liang ◽  
Liantao Li ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Structured Interview ◽  
Multivariable Logistic Regression Analysis ◽  
Major Depressive ◽  
Renal Hyperfiltration ◽  
A Minor ◽  
Major Depressive Episodes ◽  
Depressive Episodes

Background: Depression is prevalent in patients with all stages of CKD and is associated with adverse outcome. Abnormally elevated GFR, or hyperfiltration, may play a crucial role in the initiation and progression of CKD. However, the association between depression and hyperfiltration is not known. The aim of this study is to investigate the relationship between depression and hyperfiltration. Methods: This was an observational cross-sectional study. A total of 3,716 volunteers (1,303 males and 2,413 females) aged 40–75 years without CKD from a community in China were included for the study. Depressive symptoms and the presence of a minor or major depressive episode were assessed with the 9-item Patient Health Questionnaire (PHQ-9) and Diagnostic and Statistical Manual of Mental Disorders (4th edition)-based structured interview, respectively. Results: The mean age of the participants in the present study was 53.8 ± 9.0 years. 115 participants had clinically relevant depression, and 122 participants had a minor or major depressive episode. In a multivariable logistic regression analysis adjusted for potential confounders, the association between clinically relevant depression and renal hyperfiltration remained significant in men but not in women. As compared with men without depression (PHQ <5) or depressive episodes, those with clinically relevant depression (PHQ ≥10) had a significantly higher risk of renal hyperfiltration. The fully adjusted OR (95% CI) was 4.81 (1.62–14.30, p = 0.005), those with a major depressive episode had a higher risk of renal hyperfiltration (OR 7.45; 95% CI 2.04–27.21, p = 0.002). Conclusion: Depressive symptoms and major depressive episodes are associated with renal hyperfiltration in middle-aged and elderly Chinese men without CKD. Future studies are needed to verify and clarify the role of depression in the development of abnormally high eGFR and CKD.

scholarly journals Characteristics Associated with Depression Severity in 270 Juveniles in a Major Depressive Episode

2021 ◽  
Vol 11 (4) ◽  
pp. 440
Author(s):  
Giulia Serra ◽  
Maria Elena Iannoni ◽  
Monia Trasolini ◽  
Gino Maglio ◽  
Camilla Frattini ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Rating Scale ◽  
Severe Depression ◽  
Psychotic Symptoms ◽  
Depression Severity ◽  
Suicidal Risk ◽  
Major Depressive ◽  
Mood Lability ◽  
Linear Regression Modeling

Introduction: Severe depression is prevalent in young persons and can lead to disability and elevated suicidal risk. Objectives: To identify clinical and demographic factors associated with the severity of depression in juveniles diagnosed with a major mood disorder, as a contribution to improving clinical treatment and reducing risk of suicide. Methods: We analyzed factors associated with depression severity in 270 juveniles (aged 6–18 years) in a major depressive episode, evaluated and treated at the Bambino Gesù Children’s Hospital of Rome. Depressive symptoms were rated with the revised Children’s Depression Rating Scale (CDRS-R) and manic symptoms with the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) Mania Rating Scale (K-SADS-MRS). Bivariate comparisons were followed by multivariable linear regression modeling. Results: Depression severity was greater among females than males (55.0 vs. 47.2), with the diagnosis of a major depressive disorder (MDD) vs. bipolar disorder (BD; 53.8 vs. 49.3), and tended to increase with age (slope = 1.14). Some symptoms typical of mania were associated with greater depression severity, including mood lability, hallucinations, delusions, and irritability, whereas less likely symptoms were hyperactivity, pressured speech, grandiosity, high energy, and distractibility. Factors independently and significantly associated with greater depression severity in multivariable linear regression modeling were: MDD vs. BD diagnosis, female sex, higher anxiety ratings, mood lability, and irritability. Conclusions: Severe depression was significantly associated with female sex, the presence of some manic or psychotic symptoms, and with apparent unipolar MDD. Manic/psychotic symptoms should be assessed carefully when evaluating a juvenile depressive episode and considered in treatment planning in an effort to balance risks of antidepressants and the potential value of mood-stabilizing and antimanic agents to decrease the severity of acute episodes and reduce suicidal risk.

scholarly journals Depressive Symptoms Versus Depression in Older Adults in a Rural Community

2014 ◽  
Vol 4 (3) ◽  
pp. 321-327
Author(s):  
Clemente Cordero Sánchez ◽  
Guillermina García Madrid ◽  
Marcela Flores Merlo ◽  
Francisco Javier Báez Hernández ◽  
Alejandro Torres Reyes ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Rural Community ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Severe Depression ◽  
Female Gender ◽  
Geriatric Syndrome ◽  
Mild Depression ◽  
Major Depressive

Depression is a mood disorder characterized by loss of interest or pleasure in activities of daily living. Frequent and disabling geriatric syndrome that often goes unnoticed, which generates physical and functional. The objective was to know the depressive symptoms in older adults in a rural community in the state of Puebla, Mexico. Study was descriptive, correlational, cross, made of 155 seniors was an applied to Scale Center for Epidemiologic Studies Depression CES-D and the Scale of Yesavage. The age range of older adults was 60 to 90 years, with a predominance of female gender in 65.2%, the CES-D reported 18.7% were found no clinical y significant symptoms, 70.3% in symptoms of sub- threshold depression, 9% in possible major depressive episode, 1.9% in probable major depressive episode. Similar results to those of Scale of Yesavage 43.2% found no evidence of depression, 32.9% with mild depression, 17.4% with moderate depression and 6.5% with severe depression. Noticing a difference by gender (Women=8482.00, Male=3608.00, p=.023). Knowing depressive symptoms in older adults can implement care interventions based on scientific evidence.

scholarly journals Depressive Symptoms Versus Depression in Older Adults in a Rural Community

2014 ◽  
Vol 4 (3) ◽  
pp. 321-327
Author(s):  
Clemente Cordero Sánchez ◽  
Guillermina García Madrid ◽  
Marcela Flores Merlo ◽  
Francisco Javier Báez Hernández ◽  
Alejandro Torres Reyes ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Rural Community ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Severe Depression ◽  
Female Gender ◽  
Geriatric Syndrome ◽  
Mild Depression ◽  
Major Depressive

Depression is a mood disorder characterized by loss of interest or pleasure in activities of daily living. Frequent and disabling geriatric syndrome that often goes unnoticed, which generates physical and functional. The objective was to know the depressive symptoms in older adults in a rural community in the state of Puebla, Mexico. Study was descriptive, correlational, cross, made of 155 seniors was an applied to Scale Center for Epidemiologic Studies Depression CES-D and the Scale of Yesavage. The age range of older adults was 60 to 90 years, with a predominance of female gender in 65.2%, the CES-D reported 18.7% were found no clinical y significant symptoms, 70.3% in symptoms of sub- threshold depression, 9% in possible major depressive episode, 1.9% in probable major depressive episode. Similar results to those of Scale of Yesavage 43.2% found no evidence of depression, 32.9% with mild depression, 17.4% with moderate depression and 6.5% with severe depression. Noticing a difference by gender (Women=8482.00, Male=3608.00, p=.023). Knowing depressive symptoms in older adults can implement care interventions based on scientific evidence.

Cerebrovascular reactivity over time-course – From major depressive episode to remission

2010 ◽  
Vol 44 (3) ◽  
pp. 132-136 ◽  
Author(s):  
Harald Lemke ◽  
Ana Gómez-Carrillo de Castro ◽  
Peter Schlattmann ◽  
Isabella Heuser ◽  
Peter Neu
Keyword(s):  
Depressive Episode ◽  
Time Course ◽  
Major Depressive Episode ◽  
Cerebrovascular Reactivity ◽  
Major Depressive ◽  
Over Time

Depressive symptoms in chronic schizophrenia patients: any differences between patients with and without a major depressive episode?

2003 ◽  
Vol 18 (3) ◽  
pp. 137-139 ◽  
Author(s):  
Yasuhiro Kaneda
Keyword(s):  
Depressive Symptoms ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Depression Scale ◽  
Chronic Schizophrenia ◽  
Depression Score ◽  
Major Depressive

AbstractThe author investigated the differences between schizophrenia patients with and without a major depressive episode (MDE) using the Japanese Calgary Depression Scale for Schizophrenics. The total depression score was correlated with the dosage of antipsychotics in patients without an MDE, but such a correlation was not found in patients with an MDE.

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