scholarly journals 460. Point-of-Care, In-Home SARS-CoV-2 IgG Antibody Testing to Assess Seroprevalence in At-Risk Health Care Workers

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S297-S297
Author(s):  
Eric G Meissner ◽  
Christine Litwin ◽  
Tricia Crocker ◽  
Elizabeth Mack ◽  
Lauren Card
Keyword(s):  
Health Care ◽  
At Risk ◽  
Health Care Workers ◽  
Medical Center ◽  
Point Of Care ◽  
Academic Medical Center ◽  
Significant Risk ◽  
Documented Infection ◽  
Inconclusive Result ◽  
Care Workers

Abstract Background Health care workers are at significant risk for infection with the novel coronavirus SARS-CoV-2. Methods We utilized a point-of-care, lateral flow SARS-CoV-2 IgG immunoassay (RayBiotech) to conduct a seroprevalence study in a cohort of at-risk health care workers (n=339) and normal-risk controls (n=100) employed at an academic medical center. To minimize exposure risk while conducting the study, consents were performed electronically, tests were mailed and then self-administered at home using finger stick blood, and subjects uploaded a picture of the test result while answering an electronic questionnaire. We also validated the assay using de-identified serum samples from patients with PCR-proven SARS-CoV-2 infection. Results Between April 14th and May 6th 2020, 439 subjects were enrolled. Subjects were 68% female, 93% white, and most were physicians (38%) and nurses (27%). In addition, 37% had at least 1 respiratory symptom in the prior month, 34% had cared for a patient with known SARS-CoV-2 infection, 57% and 23% were worried about exposure at work or in the community, respectively, and 5 reported prior documented SARS-CoV-2 infection. On initial testing, 3 subjects had a positive IgG test, 336 had a negative test, and 87 had an inconclusive result. Of those with an inconclusive result who conducted a repeat test (85%), 96% had a negative result. All 3 positive IgG tests were in subjects reporting prior documented infection. Laboratory validation showed that of those with PCR-proven infection more than 13 days prior, 23/30 were IgG positive (76% sensitivity), whereas 1/26 with a negative prior PCR test were seropositive (95% specificity). Repeat longitudinal serologic testing every 30 days for up to 4 times is currently in progress. Conclusion We conducted a contact-free study in the setting of a pandemic to assess SARS-CoV-2 seroprevalence in an at-risk group of health care workers. The only subjects found to be IgG positive were those with prior documented infection, even though a substantial proportion of subjects reported significant potential occupational or community exposure and symptoms that were potentially compatible with SARS-COV-2 infection. Disclosures All Authors: No reported disclosures

Cross-sectional study of hepatitis B antibody status in health care workers immunized as children at an academic medical center in Wisconsin

Vaccine ◽  
2020 ◽  
Vol 38 (7) ◽  
pp. 1597-1600
Author(s):  
Alicia M. Ritscher ◽  
Megan LeClair-Netzel ◽  
Nicholas J. Friedlander ◽  
Danielle N. Howard Stewart ◽  
Mallory Wagner ◽  
...  
Keyword(s):  
Health Care ◽  
Hepatitis B ◽  
Health Care Workers ◽  
Medical Center ◽  
Academic Medical Center ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Academic Medical ◽  
Care Workers

Lactation Space Experiences and Preferences Among Health Care Workers in an Academic Medical Center

2018 ◽  
Vol 13 (9) ◽  
pp. 607-613 ◽  
Author(s):  
Dare Henry-Moss ◽  
Stephanie Abbuhl ◽  
Lisa Bellini ◽  
Diane L. Spatz
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Medical Center ◽  
Academic Medical Center ◽  
Academic Medical ◽  
Care Workers

Knowledge of HIV Transmission and Risk Behaviour in Kenyan Health Care Workers

1993 ◽  
Vol 4 (4) ◽  
pp. 200-203 ◽  
Author(s):  
Karen E Rogstad ◽  
G Tesfaledet ◽  
Mohammed S Abdullah ◽  
Imtyaz H Ahmed-Jushuf
Keyword(s):  
Health Care ◽  
At Risk ◽  
Risk Factor ◽  
Sexual Behaviour ◽  
Health Care Workers ◽  
Hiv Transmission ◽  
Significant Risk ◽  
Risk Behaviour ◽  
Sexual Risk Behaviour ◽  
Care Workers

In order to determine knowledge of HIV transmission, sexual risk behaviour and perception of risk in African health care workers, 200 employees at the Aga Khan Hospital, Nairobi, Kenya, were asked to complete an anonymous self-administered questionnaire. There was a 75% response rate. Twenty-five per cent believed that condoms were not protective against HIV transmission. Eighty-nine per cent believed oral sex to be a risk factor, as did 70% for kissing, 41% for masturbation of a partner and 43% for nursing an AIDS patient. Younger people were more likely to think condoms were ineffective ( P = 0.007) and that insect bites were a significant risk factor ( P = 0.004). Twenty-seven per cent had changed their sexual behaviour as a result of the AIDS epidemic, but 48% did not use condoms with non-regular partners. Four had current or previous homosexual relationships. Seventy per cent believed they were at risk of being HIV positive but only 12% had been tested. We have shown that even in the educated group, misconceptions regarding HIV transmission were high and many continue to be at risk for their sexual behaviour. In addition, in-service training regarding HIV transmission should be considered for health care workers in Africa.

COVID-19 in healthcare workers (literature review and own data)

2021 ◽  
Vol 61 (1) ◽  
pp. 18-26
Author(s):  
Lyubov A. Shpagina ◽  
Lyudmila P. Kuzmina ◽  
Olga S. Kotova ◽  
Ilya S. Shpagin ◽  
Natalya V. Kamneva ◽  
...  
Keyword(s):  
Health Care ◽  
At Risk ◽  
Health Care Workers ◽  
Work Experience ◽  
Medical Personnel ◽  
Scientific Data ◽  
Main Group ◽  
Panic Attacks ◽  
Care Workers ◽  
Occupational Infection

Introduction. Health care workers are at risk of infection with the SARS-CoV-2 virus. However, many aspects of the professionally conditioned COVID-19 are still poorly understood. The aim of study is to conduct a brief review and analysis of scientific data on the prevalence, features of clinical and laboratory COVID-19 syndromes in medical professionals. To evaluate the structure of post-COVID syndrome in health care workers who are observed in a large multidisciplinary medical organization that has a center for occupational pathology. To present the current state of the problem of examination of the connection of COVID-19 with the profession and admission to work in conditions of high risk of SARS-CoV-2 infection. Materials and methods. At the first stage, a brief review of the literature on the problem of COVID-19 in health care workers was performed, at the second - a single-center observational prospective study of COVID-19 convalescents. The main group consisted of health care workers (n=203), the comparison group - people who do not have occupational health risks (n=156). The groups were comparable in demographic characteristics. The work experience of the medical staff was 15 (5; 21) years. Of the participants in the main group, 20.2% worked in hospitals, and 79.8% in outpatient institutions. Three of the participants (1.5%) were employees of specialized COVID hospitals. Doctors were 25.6%, secondary medical personnel - 51.7%, junior medical and technical personnel - 22.7%. A severe form of COVID-19 was suffered by 25 (12.3%) people, after the artificial ventilation of the lungs (AVL) - two participants. The observation time is 60 days. Statistical analysis included standard methods of descriptive statistics, determination of relationships by the method of logistic regression. The significance level is p<0.05. Results. Most of the known data on COVID-19 in health care workers is obtained in cross-sectional studies. The possibility of occupational infection has been sufficiently proven. The risk probably depends on the work performed and is higher in conditions of direct contact of medical personnel with adults, potentially infected patients, but not in a specialized hospital. It is possible that the course of COVID-19 in health care workers differs from the general population of patients there is evidence of a greater frequency of weakness and myalgia. Studies of the features of post-COVID syndrome in health care workers in available sources could not be identified. According to the results of their own research, health care workers who had experienced COVID-19 had a higher frequency of central thermoregulation disorders, arrhythmias, heart failure, panic attacks and depression. Conclusions. Health care workers are at risk of COVID-19. Professionally conditioned post-COVID syndrome is characterized by the frequency of violations of the central mechanisms of thermoregulation and arrhythmias. COVID-19 in health care workers meets the definition of occupational disease.

scholarly journals Point-of-care diagnostics: needs of African health care workers and their role combating global antimicrobial resistance

2019 ◽  
Vol 30 (4) ◽  
pp. 404-410
Author(s):  
Rosalind Parkes-Ratanshi ◽  
Ruth Kikonyogo ◽  
Yu-Hsiang Hsieh ◽  
Edith Nakku-Joloba ◽  
Yukari C Manabe ◽  
...  
Keyword(s):  
Health Care ◽  
Sexually Transmitted Infections ◽  
Health Care Workers ◽  
Response Rate ◽  
Point Of Care ◽  
Rapid Test ◽  
Wait Time ◽  
Sexually Transmitted ◽  
Care Workers ◽  
Email Survey

Point-of-care tests (POCTs) offer the opportunity for increased diagnostic capacity in resource-limited settings, where there is lack of electricity, technical capacity, reagents, and infrastructure. Understanding how POCTs are currently used and determining what health care workers (HCWs) need is key to development of appropriate tests. In 2016, we undertook an email survey of 7584 HCWs who had received training at the Infectious Diseases Institute, Uganda, in a wide variety of courses. HCWs were contacted up to three times and asked to complete the survey using Qualtrics software. Of 555 participants answering the survey (7.3% response rate), 62% completed. Ninety-one percent were from Uganda and 50.3% were male. The most commonly-used POCTs were pregnancy tests (74%), urine dipstick (71%), syphilis rapid test (66%), and Gram stain (41%). The majority (74%) practiced syndromic diagnosis for sexually transmitted infections/HIV. Lack of availability of POCTs, increased patient wait time, and lack of training were the leading barriers for POCT use. Increasing POCT availability and training could improve uptake of POCTs for sexually transmitted infections in Africa and decrease syndromic management. This could reduce overtreatment and slow the emergence of antibiotic resistance. This is the first published email survey of HCWs in Uganda; mechanisms to increase the response rate should be evaluated.

scholarly journals “The right time is just after birth”: acceptability of point-of-care birth testing in Eswatini: qualitative results from infant caregivers, health care workers, and policymakers

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Emma Sacks ◽  
Philisiwe Khumalo ◽  
Bhekisisa Tsabedze ◽  
William Montgomery ◽  
Nobuhle Mthethwa ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Point Of Care ◽  
Care Workers ◽  
Birth Testing ◽  
The Right
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