scholarly journals Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Among Adults in a Tropical City of the Caribbean Area, Colombia: Are We Much Closer to Herd Immunity Than Developed Countries?

2020 ◽  
Vol 7 (12) ◽  
Author(s):  
Salim Mattar ◽  
Nelson Alvis-Guzman ◽  
Evelin Garay ◽  
Ricardo Rivero ◽  
Alejandra García ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Confidence Interval ◽  
Herd Immunity ◽  
Developed Countries ◽  
Serological Survey ◽  
Population Immunity ◽  
Caribbean Area ◽  
The Caribbean

Abstract A serological survey was carried out in Monteria (500 000 population), a mid-size city in Colombia. An overall prevalence of 55.3% (95% confidence interval, 52.5%–57.8%) was found among a sample of 1.368 people randomly selected from the population. Test positivity was related to economic characteristics with the highest prevalence found in the most impoverished areas, representing 83.8% of the city’s population. We found a prevalence that might be associated with some important level of population immunity.

Antrodia pini-cubensis, a new polypore from the Caribbean area.

1994 ◽  
Vol 47 (3) ◽  
pp. 189-192 ◽  
Author(s):  
Petr Vampola ◽  
František Kotlaba ◽  
Zdeněk Pouzar
Keyword(s):  
Caribbean Area ◽  
The Caribbean

scholarly journals The importance of supplementary immunisation activities to prevent measles outbreaks during the COVID-19 pandemic in Kenya

BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
C. N. Mburu ◽  
◽  
J. Ojal ◽  
R. Chebet ◽  
D. Akech ◽  
...  
Keyword(s):  
Vaccination Coverage ◽  
Herd Immunity ◽  
African Region ◽  
Population Immunity ◽  
Measles Outbreak ◽  
Increased Risk ◽  
Measles Vaccination ◽  
Serological Data ◽  
Measles Outbreaks ◽  
Measles Vaccination Coverage

Abstract Background The COVID-19 pandemic has disrupted routine measles immunisation and supplementary immunisation activities (SIAs) in most countries including Kenya. We assessed the risk of measles outbreaks during the pandemic in Kenya as a case study for the African Region. Methods Combining measles serological data, local contact patterns, and vaccination coverage into a cohort model, we predicted the age-adjusted population immunity in Kenya and estimated the probability of outbreaks when contact-reducing COVID-19 interventions are lifted. We considered various scenarios for reduced measles vaccination coverage from April 2020. Results In February 2020, when a scheduled SIA was postponed, population immunity was close to the herd immunity threshold and the probability of a large outbreak was 34% (8–54). As the COVID-19 contact restrictions are nearly fully eased, from December 2020, the probability of a large measles outbreak will increase to 38% (19–54), 46% (30–59), and 54% (43–64) assuming a 15%, 50%, and 100% reduction in measles vaccination coverage. By December 2021, this risk increases further to 43% (25–56), 54% (43–63), and 67% (59–72) for the same coverage scenarios respectively. However, the increased risk of a measles outbreak following the lifting of all restrictions can be overcome by conducting a SIA with ≥ 95% coverage in under-fives. Conclusion While contact restrictions sufficient for SAR-CoV-2 control temporarily reduce measles transmissibility and the risk of an outbreak from a measles immunity gap, this risk rises rapidly once these restrictions are lifted. Implementing delayed SIAs will be critical for prevention of measles outbreaks given the roll-back of contact restrictions in Kenya.

Sponge Industry of the Caribbean Area

1938 ◽  
Vol 14 (2) ◽  
pp. 201 ◽  
Author(s):  
George S. Corfield
Keyword(s):  
Caribbean Area ◽  
The Caribbean

An English Library at Trinidad, 1633

1955 ◽  
Vol 12 (1) ◽  
pp. 25-41
Author(s):  
Eleanor B. Adams
Keyword(s):  
Sixteenth Century ◽  
West Indian ◽  
The West ◽  
The Third ◽  
Caribbean Area ◽  
The Caribbean ◽  
El Dorado ◽  
Short Time

The island of Trinidad was discovered by Columbus on the third voyage in 1498. One of the largest and most fertile of the West Indian islands, for many years it remained on the fringe of European activity in the Caribbean area and on the coasts of Venezuela and Guiana. A Spanish settlement was founded there in 1532, but apparently it disintegrated within a short time. Toward the end of the sixteenth century Berrio and Raleigh fought for possession of the island, but chiefly as a convenient base for their rival search for El Dorado, or Manoa, the Golden Man and the mythical city of gold. Throughout the sixteenth and early seventeenth centuries explorers, corsairs, and contraband traders, Spanish, French, English, and Dutch, passed near its shores, and many of them may well have paused there to refresh themselves and to make necessary repairs to their vessels. But the records are scanty and we know little of such events or of the settlements that existed from time to time.

COVID-19: Are Experimental Drugs Cure or Ill?

2021 ◽  
Vol 16 ◽  
Author(s):  
Bensu Karahalil ◽  
Aylin Elkama
Keyword(s):  
Clinical Trials ◽  
Severe Acute Respiratory Syndrome ◽  
Adverse Effects ◽  
Antiviral Treatment ◽  
Herd Immunity ◽  
Mortality Rates ◽  
Death Rates ◽  
Experimental Drugs ◽  
Combined Use ◽  
The World

Background: Coronavirus disease 2019 (COVID-19) is a new strain of coronavirus. It is characterized by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has quickly influenced all over the world since it spreads easily. Common symptoms are fever, cough, difficulty in breathing and muscle aches. Despite the urgent need to find an effective antiviral treatment, already available agents are being used alone or in combination all over the world. At the beginning of the pandemic, death rates of infection caused by COVID-19 are high but "is COVID-19 responsible for all deaths?", or “are there any contributions of the frequently used drugs in this period to these deaths?” Surely herd immunity plays a major role and has the contribution in the decline in mortality rates. Meanwhile, it is kept in mind that due to safety concerns, changes have also been made to the dosage and combined use of frequently used drugs. Objective: In this review, answers to two questions above and the safety of treatments, toxicities of agents involving chloroquine, hydroxychloroquine, remdesivir, favipiravir, lopiravir/ritonavir, sarilumab, tocilizumab, siltuximab, corticosteroids and bromhexine which are the most frequently used in both Turkey and all over the world will be summarized. Conclusion: Among these drugs favipiravir seems the most promising drug due to more tolerable adverse effects. More clinical trials with large sample sizes are needed to find the most effective and safe drug for COVID-19 treatment.

scholarly journals Case study of COVID 19 from August to end of December 2020 in Babylon, Iraq

2021 ◽  
Vol 5 (3) ◽  
Keyword(s):  
Herd Immunity ◽  
Health Department ◽  
Public Health Department ◽  
Infected People ◽  
The Public ◽  
Population Immunity ◽  
Previous Infection ◽  
Study Case ◽  
Indirect Protection

Objectives: The aim of study is to study Case study of COVID 19 in Babylon Province in Iraq. Method: In January 2021 we started searching for the official source for the numbers of people infected with COVID19 within the borders of Babylon Governorate, where the Babylon Health Department was reviewed, and after that we were directed with official authorization to the Public Health Department in Babylon Governorate / Department of Communicable Diseases / Respiratory Diseases Unit (weekly periodic visit). Where the official numbers were obtained for the number of infected people and the number of deaths that occur due to complication with this infection, as well as the number of recovery cases from the date of 01/08/2020 to 01/01/2021. Results: related to the number of infected cases we see decrease the no. of infected with corona virus in Babylon Governorate from beginning the study to become lest at the end of 2020 with the significant decrease (P < 0.05) (The highest infected cases were notices in first month (1/8 – 31/8) while the lowest cases were seen in last month (1/12 – 31/12)) that may be due to: The main cause may be the most people may have gained herd immunity or population immunity, is the indirect protection from an infectious disease that happens when a population is have immunity developed through previous infection, that may refer to the end of first wave of this pandemic which start from the June. Conclusion: Knowing the pathogenesis of the virus and risk factors, increasing the experience of doctors and working cadres, increasing clinical capacity, providing specialized treatments, increasing the number of ICU beds, in addition to increasing the number of respiratory ventilators and increasing the number of tests.

Collective immunity to SARS-CoV-2 of Moscow residents during the COVID-19 epidemic period

2020 ◽  
Vol 18 (4) ◽  
pp. 8-16
Author(s):  
A.Yu. Popova ◽  
◽  
E.B. Yezhlova ◽  
A.A. Melnikova ◽  
E.E. Andreeva ◽  
...  
Keyword(s):  
Herd Immunity ◽  
Age Groups ◽  
Asymptomatic Infection ◽  
Administrative District ◽  
Cultural Workers ◽  
Population Immunity ◽  
The North ◽  
First Case ◽  
Epidemic Period ◽  
Structure Of Population

The coronavirus disease pandemic (COVID-19) was announced by WHO in February 2020. In Moscow, the first case of the disease was detected on March 2, 2020 in a man who arrived from Italy. Two weeks after the first case, there was an exponential increase in the number of cases. The incidence peaked in the 19th week of the year, followed by a steady decline, lasting 16 weeks. Objective. To investigate the level and structure of population immunity to the SARS-CoV-2 virus among the population of Moscow against the background of the incidence of COVID-19. Patients and methods. The study of population immunity of Moscow residents to SARS-CoV-2 was carried out in the period from July 1, 2020 to July 30, 2020 against the background of stabilization of the incidence rate. The work was conducted as part of the first stage of the Rospotrebnadzor project to assess population immunity to the SARS-CoV-2 virus among the population of the Russian Federation, taking into account the protocol recommended by WHO. Volunteers for the study were selected by the method of questioning and randomization. The results of the survey of 2688 people were included in the analysis. The number of volunteers in all age groups was 384–385 people. The content of specific IgG to the SARS-CoV-2 nucleocapsid was determined by the enzyme-linked immunosorbent assya using a kit produced by FBIS SRCAMB according to the manufacturer's instructions. Results. During the survey of volunteers it was found that the share of seroprevalent residents of Moscow was 22.1%. By age groups, the highest proportion of seroprevalent was found among children aged 14–17 years (44.6%), the lowest (15.9%) – among people aged 18–29 years. Seroprevalence had no gender differences. The lowest level of herd immunity was revealed in the North-Western Administrative District (16.8%), the highest – in the South-Eastern Administrative District, as well as in the Troitsky and Novomoskovsky Administrative Districts of Moscow (in both, 24.1%). The smallest number of seropositive persons was among cultural workers (5.8%), the largest – among medical workers (27.0%). In the presence of contacts with patients with COVID-19, the probability of seroconversion increases by 1.5 times, and among convalescing persons COVID-19 antibodies were detected in 60.0% of cases. The proportion of people with asymptomatic infection among seropositive residents was 82.4%. Conclusion. The results obtained make it possible to characterize the population immunity of Moscow residents and are essential for the planning and implementation of anti-epidemic measures during the incidence of COVID-19. Key words: coronaviruses, SARS-CoV-2, seroprevalence, population, COVID-19

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