scholarly journals 300Tracing the Natural History of Methicillin-Resistant Staphylococcus aureus (MRSA) Colonization among Residents of a Long Term Veterans’ Nursing Home in Pittsburgh, PA

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S125-S125
Author(s):  
Gitanjali Pai ◽  
Marilyn Wagener ◽  
Candace Cunningham ◽  
Cheryl Creen ◽  
Diana Toy ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Nursing Home ◽  
Natural History ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
History Of ◽  
Mrsa Colonization

Community-Acquired Methicillin-Resistant Staphylococcus Aureus Epidural Abscess With Bacteremia and Multiple Lung Abscesses: Case Report

2009 ◽  
Vol 18 (1) ◽  
pp. 86-88 ◽  
Author(s):  
Aaron S. Bruns ◽  
Namita Sood
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Distress Syndrome ◽  
Systemic Infection ◽  
Signs And Symptoms ◽  
Methicillin Resistant ◽  
History Of ◽  
Systemic Manifestations ◽  
Parenchymal Damage

A systemic infection due to community-acquired methicillin-resistant Staphylococcus aureus occurred in a hospital-naive 17-year-old girl with no history of soft-tissue infection. Although the initial signs and symptoms were indolent, systemic manifestations occurred, including extensive lung parenchymal damage and acute respiratory distress syndrome. The patient required long-term mechanical ventilation and was given linezolid for 8 weeks. Blood cultures eventually became negative for the staphylococci, and the patient was discharged to a rehabilitation facility. A probable source of the infection was the patient’s self-cutting and self-piercing.

Methicillin-Resistant Staphylococcus aureus in a Nursing Home and Affiliated Hospital: A Four Year Prespective

1993 ◽  
Vol 14 (6) ◽  
pp. 331-336 ◽  
Author(s):  
Larry J. Strausbaugh ◽  
Cleone Jacobson ◽  
Terri Yost
Keyword(s):  
Staphylococcus Aureus ◽  
Nursing Home ◽  
Acute Care ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Medical Center ◽  
Care Facility ◽  
Nursing Home Care ◽  
Methicillin Resistant ◽  
Patient Transfers ◽  
Mrsa Colonization

AbstractObjectives:To determine the effect of a methicillin-resistant Staphylococcus aureus (MRSA) outbreak in a nursing home on the subsequent MRSA caseload in a closely affiliated hospital.Design:Observational and descriptive; routine and special MRSA surveillance data for nursing home and hospital were reviewed for a four-year period (1988 to 1991) as were records regarding patient transfers from nursing home to hospital.Setting:The 120-bed nursing home care unit (NHCU) and the geographically separate 434-bed acute care facility (hospital) of the Portland Veterans' Affairs Medical Center (PVAMC).Patients:Veterans hospitalized in the acute care division of NHCU.Results:Following the introduction of MRSA into the NHCU in December 1987, it quickly disseminated. Two to 32 newly colonized or infected patients were recognized in each quarter of the study period. Facilitywide prevalence surveys on two occasions disclosed MRSA colonization rates of 34% and 10%. During the study period, 15 to 54 (mean: 37.6) patients were transferred each quarter from the NHCU to the hospital of the PVAMC. The number of MRSA cases transferred ranged from 0 to 16 per quarter (mean: 5.4). During the same period, the total number of MRSA cases in the hospital increased, rising from 7 cases in 1987 to 16 in 1988, 48 in 1989, 34 in 1990, and 35 in 1991. The percentage of hospital MRSA cases accounted for by NHCU transfers was 0% in 1988, 38% in 1989, 12% in 1990, and 11% in 1991.Conclusions:Despite the steady flow of patients between the NHCU and the hospital, the MRSA outbreak in the NHCU was associated with only a modest increase in the MRSA caseload at the affiliated hospital.

scholarly journals Prevalence and molecular epidemiology of methicillin-resistant Staphylococcus aureus colonization with and without methicillin-resistant coagulase-negative Staphylococci in HIV-infected patients

2020 ◽  
Author(s):  
Ying Li ◽  
Jialing Lin ◽  
Linghua Li ◽  
Weiping Cai ◽  
Yingying Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Tract Infection ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Mainland China ◽  
Molecular Characteristics ◽  
Coagulase Negative Staphylococci ◽  
Methicillin Resistant ◽  
History Of ◽  
Mrsa Colonization

Abstract Background The global prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in human immunodeficiency virus (HIV)-infected patients is increasing, but data about it was limited in mainland China. This study aims to investigate the epidemiology of MRSA nasal colonization among HIV-infected patients in mainland China and also evaluate the impact of methicillin-resistant coagulase-negative Staphylococci (MRCoNS). Methods This cross-sectional study was designed to collect nasal samples and individual information for HIV-infected participants. Risk factors and phenotypic and molecular characteristics among those with MRSA colonization comparing those with and without MRCoNS co-colonization were analyzed.Results We found 119 (11.89%) out of 1001 HIV-infected patients were colonized with MRSA, including 41 (4.10%) with MRCoNS and 78 (7.79%) without MRCoNS. Having a history of respiratory tract infection in the previous 6 months(adjusted OR=1.64, 95% CI: 1.04-2.57) and male gender (aOR=3.92, 95% CI: 1.20-12.85) were risk factors for the overall MRSA and MRSA without MRCoNS colonization, respectively. No risk factor was associated with co-colonization of MRSA and MRCoNS. The proportions of antibiotic resistance and toxin genes as well as the distribution of molecular types for MRSA isolates were equivalent between subjects with and without MRCoNS isolates (P-value ≥0.05). Conclusions HIV-infected patients remain a highly vulnerable population for MRSA colonization, and men and prior history of respiratory tract infection are risk factors. Risk factors and phenotypic and molecular characteristics of MRSA colonization were not affected by co-colonizing with MRCoNS.

scholarly journals The Prevalence and Risk Factors Associated with Nasal Methicillin- Resistant Staphylococcus Aureus Colonization among Children in a Tertiary Hospital in Nigeria

1970 ◽  
Vol 29 (4) ◽  
Author(s):  
Kemi Elizabeth Tuta ◽  
Abiola Olukemi Okesola ◽  
Chukwuma David Umeokonkwo
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Meca Gene ◽  
Tertiary Hospital ◽  
Health Concern ◽  
Prevalence Odds Ratio ◽  
Methicillin Resistant ◽  
History Of ◽  
Mrsa Colonization

BACKGROUND: Nasal methicillin-resistant Staphylococcus aureus (MRSA) colonization is of public health concern due to increased risk of developing invasive infections and the therapeutic challenges. This concern is more among the vulnerable group. We determined the prevalence and associated risk factors of MRSA nasal carriage among children in a tertiary hospital in Nigeria.METHOD: We conducted a hospital-based, cross-sectional study among 300 children attending the outpatient clinic of a tertiary hospital recruited through systematic sampling technique. An interviewer-administered, structured questionnaire was used to obtain sociodemographic characteristics and exposure factors. Nasal swabs samples were collected and inoculated on mannitol salt agar and subcultured on nutrient agar to isolate Staphylococcus aureus. We used the conventional Polymerase Chain Reaction (PCR) technique to detect the presence of mecA gene for MRSA. We calculated the prevalence, prevalence odds ratio to determine risk factors for MRSA acquisition at 5% level of significance.RESULTS: The median age was 1.7 years (6 months-16 years). Males accounted for 60.7%, and 75% of the participants were under 5 years. Staphylococcus aureus colonization was found in 36.3% of the participants while 5.3% of the participants had MRSA identified by detecting the mecA gene. History of recent surgery in the last six months was the only independent predictor of nasal MRSA colonization among the participants (aOR=12.5; 95%CI: 2.7-50.0.)CONCLUSION: The high prevalence of MRSA colonization observed among the children in this study suggests the need to consider screening children with history of previous surgery as infection control and prevention intervention for MRSA.

scholarly journals Colonization of Methicillin-resistant Staphylococcus aureus (MRSA) and History of Hospitalization: how strong do they correlate in ICU Patients?

2015 ◽  
Author(s):  
Beladenta Amalia ◽  
Yulia Rosa Saharman
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Cross Sectional ◽  
Icu Patients ◽  
Methicillin Resistant ◽  
Icu Admission ◽  
Microbiological Examination ◽  
History Of ◽  
Mrsa Colonization

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the Multidrug-resistant organisms (MDRO) which has been quite an endemic in many healthcare facilities, especially in the Intensive Care Unite (ICU) of hospitals. History of patients’ hospitalization before ICU admission has been considered to be one of the risk factors for MRSA colonization in patients. Problems arised after knowing that ICU patients with MRSA colonization are at high risk of MRSA infection. Therefore, we require data of MRSA colonization associated history of patients’ hospitalization before ICU admission in hopes that the incidence of MRSA colonization in Indonesia hospitals can be reduced. This is an analytical cross sectional study using secondary data results from microbiological examination of swabs (nose, underarms, and rectum) and medical records of 109 patients from the Central ICU RSCM on January 2011 until August 2011. Sample selection was conducted by consecutive sampling. Microbiological examination results which were used in this study were the results of MRSA resistance test both in patients who had history of hospitalization before ICU admission and those who did not. Data was analyzed using Chi-squared test. The result of comparing data between the proportion of patients with positive MRSA colonization and had history of hospitalization to the proportion of patients with positive MRSA colonization but did not have history of hospitalization was PR (prevalence ratio)=1,206 with significance value p=0,307 and CI95% -3,087; 5,499. This suggests that history of patients’ hospitalization before ICU admission was not the only factor to affect MRSA colonization. Antibiotic administrations and prior contact with MRSA carrier in the community might be other risk factors which may obscure this result. It indicates that hospitals should conduct routine MRSA colonization screening to all patients, regardless of their history of hospitalization, as a standard precaution for infection control.

Double-swab 5% versus single-swab 10% iodophor for reducing methicillin-resistant Staphylococcus aureus with routine chlorhexidine bathing

2021 ◽  
pp. 1-3
Author(s):  
Lauren T. Heim ◽  
Loren G. Miller ◽  
Raveena D. Singh ◽  
James A. McKinnell ◽  
Tabitha D. Catuna ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cohort Study ◽  
Nursing Home ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Nursing Home Residents ◽  
Nasal Carriage ◽  
Methicillin Resistant ◽  
Chlorhexidine Bathing

Abstract In a prospective cohort study, we compared a 2-swabs-per-nostril 5% iodophor regimen with a 1-swab-per-nostril 10% iodophor regimen on methicillin-resistant Staphylococcus aureus carriage in nursing-home residents. Compared with baseline, both single-swab and double-swab regimens resulted in an identical 40% reduction in nasal carriage and 60% reduction in any carriage, skin or nasal.

scholarly journals Utility of Methicillin-Resistant Staphylococcus aureus Nares Screening in Hospitalized Children with Acute Infectious Disease Syndromes

Antibiotics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1434
Author(s):  
Ashley Sands ◽  
Nicole Mulvey ◽  
Denise Iacono ◽  
Jane Cerise ◽  
Stefan H. F. Hagmann
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Hospitalized Children ◽  
Methicillin Resistant ◽  
Osteoarticular Infections ◽  
Clinical Culture ◽  
Acute Infectious Disease ◽  
Mrsa Infection ◽  
Age Range ◽  
Mrsa Colonization

Studies in adults support the use of a negative methicillin-resistant Staphylococcus aureus (MRSA) nares screening (MNS) to help limit empiric anti-MRSA antibiotic therapy. We aimed to evaluate the use of MNS for anti-MRSA antibiotic de-escalation in hospitalized children (<18 years). Records of patients admitted between 1 January 2015 and 31 December 2020 with a presumed infectious diagnosis who were started on anti-MRSA antibiotics, had a PCR-based MNS, and a clinical culture performed were retrospectively reviewed. A total of 95 children were included with a median age (range) of 2 (0–17) years. The top three diagnosis groups were skin and soft tissue infections (n = 38, 40%), toxin-mediated syndromes (n = 17, 17.9%), and osteoarticular infections (n = 14, 14.7%). Nasal MRSA colonization and growth of MRSA in clinical cultures was found in seven patients (7.4%) each. The specificity and the negative predictive value (NPV) of the MNS to predict a clinical MRSA infection were both 95.5%. About half (n = 55, 57.9%) had anti-MRSA antibiotics discontinued in-house. A quarter (n = 14, 25.5%) were de-escalated based on the negative MNS test alone, and another third (n = 21, 38.2%) after negative MNS test and negative culture results became available. A high NPV suggests that MNS may be useful for limiting unnecessary anti-MRSA therapy and thereby a useful antimicrobial stewardship tool for hospitalized children. Prospective studies are needed to further characterize the utility of MNS for specific infectious diagnoses.

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