Possible Barriers Further Down the Slope

2020 ◽  
pp. 111-133
Author(s):  
John H. Evans
Keyword(s):  
Sexual Reproduction ◽  
Genetic Modification ◽  
Medical Profession ◽  
Human Species ◽  
Goals Of Medicine ◽  
The Third ◽  
Liberal Eugenics ◽  
The Family

This chapter examines hypothetical barriers on the slope below where the somatic/germline and disease/enhancement walls once were. The first is the goals of medicine barrier, where any trait that the medical profession defines as a disease could be modified. The second is the family genes barrier, where people would be allowed to modify their children to any set of traits that the parents could in principle produce through sexual reproduction. The third is the boundary of humanity barrier, where any genes from outside of the human species are not allowed. Finally, the liberal eugenics barrier would allow any genetic modification that did not harm someone else.

Zakat as a Measure of Social Justice in Islamic Finance : An Accountant’s Overview

2013 ◽  
Vol 1 (1) ◽  
pp. 64 ◽  
Author(s):  
Pranam Dhar
Keyword(s):  
Social Justice ◽  
Islamic Finance ◽  
Poverty Eradication ◽  
The Third ◽  
The Family ◽  
Additional Amount ◽  
Important Form

Zakat is an important form of religiously mandated charity under Islam. It is the third pillar of Islam. The giving of Zakat is important for Muslims, as this leads to purification of their wealth from all sins. This paper examines the role of Zakat as an instrument of social justice and poverty eradication in society. Each Muslim calculates his or her own Zakat individually. Generally, this involves the payment each year of two and a half percent of one's capital, after the needs of the family have been met. One can donate additional amount as an act of voluntary charity but Zakat is fundamental to every Muslim. Zakat is the Islamic contribution to social justice: those who have to give charity share the benefit of their prosperity to those who have fallen short. This is the Islamic approach to remove greed and envy and to purify one's soul based on good intentions. This is the institution of Zakat in Islam. The institution of Zakat serves to eradicate poverty in the community and uphold the light of Islam. Allah says “whatever is paid as Zakat for the sake of Allah shall be rewarded in manifolds”.

Factor X Deficiency Due to a Compound Heterozygosis Between a New Mutation (Gla72Asp) in Exon 2 and an Already Known one (Gly154Arg) in Exon 5: Factor X Mar Del Plata1)

2019 ◽  
Vol 19 (2) ◽  
pp. 169-173
Author(s):  
Antonio Girolami ◽  
Diana Noemi Garcia de Paoletti ◽  
Marcelo Leonardo Nenkies ◽  
Silvia Ferrari ◽  
Hugo Guglielmone
Keyword(s):  
Bleeding Tendency ◽  
Bleeding Disorders ◽  
Factor X ◽  
Substitution Therapy ◽  
New Mutation ◽  
Exon 2 ◽  
The Third ◽  
The Past ◽  
Factor X Deficiency ◽  
The Family

Background: Investigation of rare bleeding disorders in Latin-America. Objective: The report of a new case of FX deficiency due to a compound heterozygosis. Methods: Accepted clotting procedures were used. Sequencing of DNA was carried out by means of Applied Biosystems Instruments. Results: A compound heterozygote due to the association of a new mutation (Gla72Asp) with an already known mutation (Gly154Arg) of the FX gene is reported. The proposita is a 38 year old female who had a moderate bleeding tendency (menorrhagia, epistaxis, easy bruising). The proposita has never received substitution therapy but in the occasion of a uterine biopsy. The mother was asymptomatic but was a heterozygote for the new mutation. The father was asymptomatic but had deserted the family and could not be investigated. After this abandonment the mother of the proposita re-married with an asymptomatic man and she gave birth to a son who was asymptomatic but was also heterozygous for the new mutation (Gla72Asp). As a consequence it has to be assumed that the first husband of the mother of the proposita was heterozygous for the known mutation (Gly154Arg). Conclusion: This is the third case of a new mutation in the FX gene reported, during the past few years, in Argentina.

Ennius’ imago between Tomb and Text

2018 ◽  
Author(s):  
Francesca Martelli
Keyword(s):  
The Third ◽  
The Family

Between the third and first centuries BCE, a tomb near the Via Appia not only served as a funerary monument for the Scipiones but was also believed to have once contained the statue of a man from outside the family: Quintus Ennius. This chapter considers how Ennius’ poetry and portrait contributed to the circulation of political prestige. Linking the story of his statue to a later image of the poet in Varro’s De poetis, it argues that Varro’s collection of author portraits and the practice of erecting busts of authors in libraries are best seen as a form of entombment—situating the poet’s imago alongside those of his literary forebears in a space that recognizes their identity as a group, much like the tomb of the Scipiones, or, indeed, any Roman atrium that collects the imagines of a family’s ancestors.

scholarly journals Diunsa: An Entrepreneurial Family’s Digital Response to COVID-19

2021 ◽  
pp. 251512742110331
Author(s):  
Lauri Union ◽  
Carmen Suen ◽  
Rubén Mancha
Keyword(s):  
Customer Service ◽  
Family Business ◽  
Service Operations ◽  
State Of Emergency ◽  
Supply Chain Disruptions ◽  
Online Retail ◽  
External Resources ◽  
The Third ◽  
The Family ◽  
Brick And Mortar

On March 15, 2020, in response to the Covid-19 pandemic, the Honduran government unexpectedly announced a state of emergency and mandated immediate closure of all businesses. Diunsa closed its six stores. The family-owned retailer had anticipated supply chain disruptions, stocked from alternative suppliers, and formed a crisis management team. Now, to keep the business afloat during the unexpected closure and retain all its employees on the payroll, the company had to move sales from the brick-and-mortar stores to an incomplete online retail site. The third generation in the family business—the Faraj siblings, all in their 20’s—led the critical transition online and response to setbacks. As digital-native millennials, they helped improve the website, customer service, operations, and delivery in a short amount of time and using external resources and various technologies. As the situation stabilized, Diunsa’s leadership asked: How will Diunsa build on the momentum for digital transformation and turn its tactical actions into a digital strategy? How can we continue to tap into the leadership of our up-and-coming generation to achieve these goals?

scholarly journals How to talk with the family of a dying patient: anger to understanding, rage to compassion, loss to acceptance

2021 ◽  
pp. bmjspcare-2021-002971
Author(s):  
Moshe Y Flugelman
Keyword(s):  
Goal Setting ◽  
Stressful Situation ◽  
Family Needs ◽  
The Third ◽  
Single Entity ◽  
The Family ◽  
Patient Families ◽  
The Difference ◽  
Dying Patient

Informing families about the impending or actual death of their relatives is one of the most challenging and complex tasks a physician may face. The following article describes goal setting and provides five roles/recommendations for conducting the encounter with patient families regarding the imminent or actual death of their relatives. Importantly, the encounter should be family-centred, and the physician should be highly attentive to family needs. The following roles should be applied based on family needs and should not be sequential as numbered. The first and basic role is to inform the family at the earliest possible time and as often as possible. The second goal of the physician is to convey to the family that their relative received the needed therapy during his hospitalisation or in the community. The third goal of the physician is to help the family reach acceptance of the death of their relative and leave the hospital having moved beyond anger and bargaining. The fourth goal of the physician during the encounters is to reduce or alleviate guilt by stating that nothing could have changed the course of the disease and that all efforts were made to save the patient. The fifth role of the physician is to try and help the family as a single entity and maintain their unity during this stressful situation. Following these roles/methods will help families in the stressful situation and will create the difference between anger and understanding, rage and compassion, and loss and acceptance.

Strategies to increase compliance with out-patient aftercare among patients referred to a psychiatric emergency department: a multi-centre controlled intervention study

1998 ◽  
Vol 28 (4) ◽  
pp. 949-956 ◽  
Author(s):  
D. SPOOREN ◽  
C. VAN HEERINGEN ◽  
C. JANNES
Keyword(s):  
Emergency Department ◽  
Treatment Compliance ◽  
Psychiatric Emergency ◽  
Family Presence ◽  
Experimental Procedure ◽  
The Third ◽  
Randomized Controlled ◽  
The Family ◽  
Referral Compliance ◽  
Motivational Counselling

Background. Compliance with referral for out-patient aftercare of psychiatric emergency patients is limited. This study investigated the efficacy of a combination of several referral strategies (fixed appointment, involvement of the family, presence of the aftercare person, motivational counselling) in increasing referral and treatment compliance of patients referred to the psychiatric emergency department of three general hospitals.Methods. A randomized controlled design was used to assess the effect of this experimental condition on referral compliance and on continuation of aftercare treatment.Results. A significant beneficial effect on compliance with the referral was found in two hospitals and a near-significant effect in the third. After 3 months of aftercare, the influence of the experimental procedure on adherence to therapy was still significant in two hospitals, but not in the third.Conclusions. Helping the patient to attend an initial appointment can be achieved by a combination of practical and organizational arrangements.

Trimethylaminuria (‘fish-odour syndrome’): A study of an affected family

1988 ◽  
Vol 74 (3) ◽  
pp. 231-236 ◽  
Author(s):  
Makram Al-Waiz ◽  
Riad Ayesh ◽  
Stephen C. Mitchell ◽  
Jeffrey R. Idle ◽  
Robert L. Smith
Keyword(s):  
Oral Administration ◽  
Inborn Error ◽  
Autosomal Recessive ◽  
Oral Challenge ◽  
Recessive Trait ◽  
Autosomal Recessive Trait ◽  
Challenge Dose ◽  
The Third ◽  
The Family ◽  
Body Odour

1. Beginning with a single propositus, who had been previously diagnosed at the age of 10 as suffering from trimethylaminuria (fish-odour syndrome), both her parents and two sisters were investigated biochemically with respect to their ability to N-oxidize trimethylamine (TMA), both when derived from the diet and when administered exogenously. 2. Both the propositus and a second sister were markedly deficient in their ability to N-oxidize TMA, both when derived from the diet and when given as such; furthermore, both siblings readily developed the symptoms of fish-odour syndrome as characterized by a strong objectionable breath and body odour shortly after the oral administration of TMA (300 mg). 3. At this dose level of TMA, neither of the parents nor the third sister showed any evidence of impaired N-oxidation ability nor did they experience any ‘fish-odour’ symptoms. 4. With an oral challenge of 600 mg of TMA, both the parents showed a clear impairment of N-oxidation capacity which was not seen in six healthy unrelated volunteers. Both parents experienced a fish-odour syndrome at this level of TMA challenge. 5. The family data support the hypothesis that trimethylaminuria is an inborn error in the ability to N-oxidize TMA which is inherited as an autosomal recessive trait. Furthermore, experience with this family suggests that an oral challenge dose with 600 mg of TMA may be used to identify carriers of the condition.

A new genus and species of groundwater isopod of the family Protojaniridae (Isopoda: Asellota: Gnathostenetroidoidea) from southern Chile

Zootaxa ◽  
2021 ◽  
Vol 4966 (5) ◽  
pp. 550-562
Author(s):  
JORGE PÉREZ-SCHULTHEISS ◽  
GEORGE D. F. WILSON
Keyword(s):  
New Genus ◽  
South American ◽  
New Taxon ◽  
Southern Chile ◽  
New Genus And Species ◽  
The Third ◽  
The Family ◽  
Apical Lobe ◽  
Antennal Scale ◽  
Freshwater Springs

A new asellotan isopod of the family Protojaniridae Fresi, Idato & Scipione, 1980 is described from freshwater springs in the Osorno province, Los Lagos region, southern Chile. Wiyufiloides osornoensis gen. & sp. n. is the third South American protojanirid species and the first known groundwater isopod in Chile. The new genus and species is principally characterized by the presence of a vestigial antennal scale, a strongly subchelate pereiopod I and the absence of an apical lobe on the protopod of pleopod II. The new taxon is described in detail and figures are given. 

The experience of non-traditional study of the poetics of literary works (on the example of the book “Fontanelle” by Meir Shalev)

2021 ◽  
pp. 58-75
Author(s):  
Vadim Markovich Rozin
Keyword(s):  
New World ◽  
Human Life ◽  
Literary Work ◽  
The Third ◽  
The Family ◽  
Gradual Development ◽  
History Of ◽  
Family And Marriage ◽  
Nontraditional Approach ◽  
Empirical Material

This article offers a nontraditional approach towards studying the poetics of literary work, which considers personality of the reader and analysis of the reality that he reconstructs and experiences. The empirical material is comprised on the authorial analysis of the poetics of Meir Shalev's novel “Fontanelle”. This literary work features the four major themes: love of the protagonist Michael, creation of the new world from its inception, the characteristic of life values of a person, and discussion of the peculiarities of reality that Meir Shalev builds as an artist. In the first theme, the author reveals several images of love, reflecting on the mystical love of the protagonist for the young woman Ana, love in the family and marriage, love for children. At the same time, the author discusses not only the way that Meir Shalev understands and describes love in “Fontanelle”, but also talks about the own interpretation of love. In the plotline of the second theme, the author also distinguishes two lines: the story the protagonist’s grandfather Apupa, who carries his beloved Amuma on his shoulders across the country, seeking a place where they could create a home and family; and the story of gradual development of a small settlement into a city, created by Apupa and Amuma on the mountain, and several Jewish families at the lower valley. Discussing in the third topic the anchors of human life, the author emphasizes such values as effort, love, family and family line, creativity, indicating that Michael is not alone, he is loved, he gets involved in family history, as well as the history of Israel and Jewish culture, drawing strength in the heroes of this story. The last part of the article gives characteristic to the reality of “Fontanelle” and explains why the author liked it.

scholarly journals Von hippel-lindaus disease: Report of three cases and review of the literature

1995 ◽  
Vol 53 (4) ◽  
pp. 782-788 ◽  
Author(s):  
Luiz F. Bleggi-Torres ◽  
Lúcia de Noranha ◽  
J. Fillus Neto ◽  
José E. Queiroz Telles ◽  
Luiz E. Madalozzo
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Review Of The Literature ◽  
The Third ◽  
The Family ◽  
Cerebellar Haemangioblastoma ◽  
Atypical Meningiomas ◽  
Cns Lesions

The authors present the autopsy findings of two related patients and the biopsy findings of a thrid member of the family. The oldest member was 34 years old at death and on postmortem examination he had haemangioblastomas in the retina, cerebellum, medulla and spinal cord. Other findings were renal cell carcinoma, phaechromocytoma, cysts of kidney and pancreas, hydromyelia and atypical meningiomas. His brother died when 30 years old. The autopsy revealed haemangioblastomas of cerebellum, renal cell carcinoma and a clear cell cystadenoma of epididymus. The third patient was the daughter of the first and presented with headache and dizziness. CT-scan showed a cerebellar haemangioblastoma. Epidemiological considerations on the commonest visceral and CNS lesions and a review of current diagnostic criteria are discussed.

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