scholarly journals Principal Components of Heritability From Neurocognitive Domains Differ Between Families With Schizophrenia and Control Subjects

2012 ◽  
Vol 39 (2) ◽  
pp. 464-471 ◽  
Author(s):  
Howard Wiener ◽  
Lambertus Klei ◽  
Monica Calkins ◽  
Joel Wood ◽  
Vishwajit Nimgaonkar ◽  
...  
Keyword(s):  
Principal Components ◽  
Control Subjects ◽  
And Control

scholarly journals Alterations in Brain Morphology by MRI in Adults with NF1

2019 ◽  
Author(s):  
Su Wang ◽  
Victor-Felix Mautner ◽  
Jan M. Friedman ◽  
Manraj K. S. Heran
Keyword(s):  
Corpus Callosum ◽  
Principal Components ◽  
Psychometric Testing ◽  
Clinical Severity ◽  
Brain Morphology ◽  
Control Subjects ◽  
Unaffected Control ◽  
And Control ◽  
Mri Measurements ◽  
Age And Sex

ABSTRACTObjectiveTo explore and characterize alterations in brain morphology by MRI in adults with neurofibromatosis 1 (NF1).MethodsMRI measurements of 29 intracranial structures were obtained for 389 adults with NF1 and 112 age- and sex-matched unaffected control subjects. A subset of NF1 patients (n = 70) was also assessed for clinical severity of NF1 features and neurological problems and received psychometric testing for attention deficiencies and IQ. Brain morphological measurements were compared between NF1 and control subjects, and correlation analyses were performed between principal components of the intracranial measurements and clinical and psychometric features.ResultsFour of nine corpus callosum measurements were significantly greater in adults with NF1 than in sex- and age-matched controls. All seven brainstem measurements were significantly greater in adults with NF1 than in controls. No robust correlations were observed between the size of these structures and clinical or neuropsychometric assessments.ConclusionsOur findings are consistent with the hypothesis that dysregulation of brain myelin production is an important manifestation of NF1 in adults.

The Effects of a Neutral Stimulus (Buzzer) on Motor Responses and Disfluencies in Normal Speakers

1969 ◽  
Vol 12 (1) ◽  
pp. 179-184 ◽  
Author(s):  
Richard R. Martin ◽  
Gerald M. Siegel
Keyword(s):  
College Students ◽  
Neutral Stimulus ◽  
Motor Responses ◽  
Control Subjects ◽  
And Control ◽  
Speaking Task

Seventy-two college students were divided into three groups: Button Push-Speech (BP-S), Speech-Button Push (S-BP), and Control. BP-S subjects pushed one of two buttons on signal for 8 min. During the last 4 min, depression of the criterion button caused a buzzer to sound. After the button-push task, subjects spoke spontaneously for 30 min. During the last 20 min, the buzzer was presented contingent upon each disfluency. S-BP subjects were run under the same procedures, but the order of button-push and speech tasks was reversed. Control subjects followed the same procedures as S-BP subjects, but no buzzer signal was presented at any time. Both S-BP and BP-S subjects emitted significantly fewer disfluencies during the last 20 min (Conditioning) than during the first 10 min (Baserate) of the speaking task. The frequency of disfluencies for Control subjects did not change significantly from Baserate to Conditioning. In none of the three groups did the frequency of pushes on the criterion button change significantly from minute to minute throughout the 8-min button-push session.

Tests for Platelet Changes, Acute Phase Reactants and Serum Lipids in Diabetes mellitus and Peripheral Vascular Disease

1982 ◽  
Vol 48 (03) ◽  
pp. 289-293 ◽  
Author(s):  
B A van Oost ◽  
B F E Veldhuyzen ◽  
H C van Houwelingen ◽  
A P M Timmermans ◽  
J J Sixma
Keyword(s):  
Diabetes Mellitus ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Acute Phase ◽  
Serum Lipids ◽  
Diabetic Patients ◽  
Peripheral Vascular ◽  
Acute Phase Reactants ◽  
Control Subjects ◽  
And Control

SummaryPlatelets tests, acute phase reactants and serum lipids were measured in patients with diabetes mellitus and patients with peripheral vascular disease. Patients frequently had abnormal platelet tests and significantly increased acute phase reactants and serum lipids, compared to young healthy control subjects. These differences were compared with multidiscriminant analysis. Patients could be separated in part from the control subjects with variables derived from the measurement of acute phase proteins and serum lipids. Platelet test results improved the separation between diabetics and control subjects, but not between patients with peripheral vascular disease and control subjects. Diabetic patients with severe retinopathy frequently had evidence of platelet activation. They also had increased acute phase reactants and serum lipids compared to diabetics with absent or nonproliferative retinopathy. In patients with peripheral vascular disease, only the fibrinogen concentration was related to the degree of vessel damage by arteriography.

scholarly journals The fate of orally administered sialic acid: First insights from patients with N-acetylneuraminic acid synthase deficiency and control subjects

2021 ◽  
Vol 28 ◽  
pp. 100777
Author(s):  
Christel Tran ◽  
Licia Turolla ◽  
Diana Ballhausen ◽  
Sandrine Cornaz Buros ◽  
Tony Teav ◽  
...  
Keyword(s):  
Sialic Acid ◽  
Acetylneuraminic Acid ◽  
Control Subjects ◽  
And Control

Mandibular deviations in TMD and non-TMD groups related to eye dominance and head posture

2002 ◽  
Vol 25 (2) ◽  
pp. 147-155 ◽  
Author(s):  
N. Pradham ◽  
G. White ◽  
N. Mehta ◽  
A. Forgione
Keyword(s):  
Head Rotation ◽  
Lateral Direction ◽  
Head Posture ◽  
Control Subjects ◽  
Eye Dominance ◽  
Pain Center ◽  
And Control ◽  
Female Subjects

This study was designed to determine whether eye-dominance affects head posture (rotation) and in turn, whether head posture is associated with mandibular frenum midline deviation, in both TMJ and control subjects. Eye dominance was determined using three tests:Porta, Hole, Point tests. Natural head posture was evaluated using the Arthrodial protractor. Mandibular frenum deviation was recorded as left, right or no deviation. Fifty female subjects were included in the study, 25 TMJ patients attending the Gelb Craniomandibular Pain Center and 25 non-TMJ control subjects. The findings indicate that eye dominance and direction of head rotation are strongly associated in both TMJ and control subjects. Further, in TMJ subjects mandibular deviation occurred in greater frequency than in controls and tends to occur in the contra lateral direction of head rotation.

Biomarkers of oxidative stress in schizophrenic and control subjects

2007 ◽  
Vol 76 (2) ◽  
pp. 73-85 ◽  
Author(s):  
J. Young ◽  
S.B. McKinney ◽  
B.M. Ross ◽  
K.W.J. Wahle ◽  
S.P. Boyle
Keyword(s):  
Oxidative Stress ◽  
Control Subjects ◽  
And Control ◽  
Biomarkers Of Oxidative Stress

Doubling time α-aminoisobutyrate transport and calcium exchange in cultured fibroblasts from cystic fibrosis and control subjects

1978 ◽  
Vol 82 (1-2) ◽  
pp. 125-131 ◽  
Author(s):  
Burton L. Shapiro ◽  
Robert J. Feigal ◽  
Nancy J. Laible ◽  
Michelle H. Biros ◽  
Warren J. Warwick
Keyword(s):  
Cystic Fibrosis ◽  
Doubling Time ◽  
Cultured Fibroblasts ◽  
Control Subjects ◽  
Calcium Exchange ◽  
And Control

SECRETION OF DIHYDROTESTOSTERONE BY HUMAN PROSTATE IN BENIGN PROSTATIC HYPERTROPHY

1974 ◽  
Vol 77 (2) ◽  
pp. 401-407 ◽  
Author(s):  
J. A. Mahoudeau ◽  
A. Delassalle ◽  
H. Bricaire
Keyword(s):  
Plasma Levels ◽  
Benign Prostatic Hypertrophy ◽  
Prostatic Hypertrophy ◽  
Human Prostate ◽  
Control Subjects ◽  
Peripheral Plasma ◽  
Significant Difference ◽  
Before And After ◽  
The Mean ◽  
And Control

ABSTRACT Plasma levels of testosterone (T) and 5α-dihydrotestosterone (DHT) were determined by radioimmunoassay in 29 patients with benign prostatic hypertrophy (BPH) and in 56 control men of various ages. No significant difference was found in T, DHT nor DHT/T ratio between BPH and control subjects of similar age. Plasma DHT was higher in the prostatic than in the peripheral veins in 8/9 patients with BPH during laparotomy, indicating a prostatic secretion of DHT. No difference in the mean T nor the mean DHT was found in peripheral plasma before and after adenomectomy.

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