Risk Factors for Vitamin A Deficiency in Rural Areas of the Philippines

1994 ◽  
Vol 40 (2) ◽  
pp. 82-87 ◽  
Author(s):  
D. S. Rosen ◽  
N. L. Sloan ◽  
A. del Rosario ◽  
T. C. de la Paz
2021 ◽  
pp. 037957212110602
Author(s):  
Mark Pretzel P. Zumaraga ◽  
Jose Maria Reynaldo Apollo Arquiza ◽  
Mae Anne Concepcion ◽  
Leah Perlas ◽  
Ma. Neda Alcudia-Catalma ◽  
...  

Background: The study aimed to identify two beta-carotene 15,15′-monooxygenase (BCMO1) mutations, namely R267S and A379V, and determine their association with vitamin A status among Filipinos 6 to 19 years old respondents of the 2013 Philippine National Nutrition Survey living in the National Capital Region. Materials and Methods: This study followed cross-sectional design. Whole blood specimen was collected in the morning and was used as source of genomic DNA and serum for retinol concentration determination. Fisher exact test was performed to determine whether genotype frequencies were associated to retinol concentrations/vitamin A deficiency status. A level of P < .05 was identified as significant. Results: A total of 693 Filipino children and adolescents were included. Of the 693, there were at least 7.6% who bears the combined mutations for R267S + A379V. Association analysis showed that an inverse relationship exists between the A379V TT variant and vitamin A status. Although the exact role of these identified polymorphisms on retinol/carotenoid metabolism need to be confirmed in dedicated functional studies. Conclusion: This study has identified for the first time the presence of 2 nonsynonymous genetic variants/mutations in the coding region of BCMO1 gene. Interestingly, one of these two variants, the A379V T, was found to be associated with vitamin A status. It is, therefore, warranted to investigate the role of BCMO1 variants for the success of supplementation programs and fortification efforts among vulnerable populations in this region. Genetic variability should be considered for future provitamin A supplementation recommendations among children and adolescents in the Philippines.


2008 ◽  
Vol 1 (1) ◽  
pp. 72-81 ◽  
Author(s):  
Kazi Md. Abul Kalam Azad

Acute respiratory infection (ARI) is a major cause of childhood mortality and morbidity in Bangladesh. The aim of this study is to identify the significant risk factors for ARI in children less than five years of age. The data in this study comes from Bangladesh Demographic and Health Survey (BDHS) 2004. In this study, a child was considered as having experienced ARI if she or he had cough in the last two weeks preceding the survey with any one of the three symptoms of short but rapid breathing, difficulty of breathing or labored inspiration. Logistic regression was used on various independent variables to find the risk factors. Results showed that child's age, sex, body weight and Vitamin A deficiency were correlated with prevalence of ARI. Additionally mother's characteristics like age, malnutrition, education level, and family's socio-economic status were found to be associated. Recommendations include more specific knowledge of ARI to adolescent mothers from the lowest wealth quintile. A community service which could include home visiting for health education, supplementation of vitamin A, and advice would be an advantage if provided for poor or teenaged pregnant women. This in turn would reduce low birth weight incidence, and subsequently reduce incidence of ARI among these children.Keywords: Acute respiratory infections (ARI); Risk factors; Infant; Child under 5 years; Bangladesh.© 2009 JSR Publications. ISSN: 2070-0237(Print); 2037-0245 (Online). All rights reserved.DOI: 10.3329/jsr.v1i1.1055


2013 ◽  
Vol 110 (S3) ◽  
pp. S36-S44 ◽  
Author(s):  
Nipa Rojroongwasinkul ◽  
Kallaya Kijboonchoo ◽  
Wanphen Wimonpeerapattana ◽  
Sasiumphai Purttiponthanee ◽  
Uruwan Yamborisut ◽  
...  

In the present study, we investigated nutritional status and health-related factors in a multistage cluster sample of 3119 Thai urban and rural children aged 0·5–12·9 years. In a subsample, blood samples were collected for the measurement of Hb, transferrin receptor, vitamin A and vitamin D concentrations. The prevalence of stunting and underweight was higher in rural children than in urban children, whereas the wasting rate was similar in both rural and urban areas. Among children aged 3·0–5·9 years, the prevalence of overweight was significantly higher in urban areas than in rural areas and so was the obesity rate in children aged 6·0–12·9 years. Protein intakes of all age groups were relatively high in both the areas. Intakes of Ca, Fe, Zn and vitamin C were significantly higher in urban areas than in rural areas. The prevalence of anaemia in rural areas was twice as high as that in urban areas, particularly in infants and young children. However, the prevalence of Fe-deficiency anaemia was similar in both urban and rural areas. While the prevalence of vitamin A deficiency (by serum retinol cut-off < 0·7 μmol/l) seemed to be very low, vitamin A insufficiency (by serum retinol cut-off < 1·05 μmol/l) was more prevalent (29·4–31·7 %) in both the areas. The prevalence of vitamin D insufficiency ranged between 27·7 and 45·6 % among the children. The present study indicates that the double burden of malnutrition is still a major public health problem in Thailand. Further studies need to explore the associated risk factors for these nutrient deficiencies. Effective strategies and actions are needed to tackle the nutritional problems in Thai children.


1979 ◽  
Vol 74 (2) ◽  
pp. 112-118
Author(s):  
FLORENTINO S. SOLON ◽  
THOMAS L. FERNANDEZ ◽  
MICHAEL C. LATHAM ◽  
BARRY M. POPKIN

1987 ◽  
Vol 15 (2) ◽  
pp. 67-72 ◽  
Author(s):  
Leena Tenkanen ◽  
Lyly Teppo

To study the importance of migration to urban area, marital status and smoking as risk factors in cancer, a cohort of 4475 Finnish men was followed up for the occurrence of cancer during the period 1964–1980. Of particular interest was the interaction of migration or marital status with smoking. For cancers at all sites, not married urbanized smoking men had the greatest risk, followed by not married native urban smokers. This pattern was mainly due to high risk of cancers of the lung and larynx among the urbanized men, with a risk peak among urbanized not married smokers. The pattern persisted even when the amount smoked was allowed for. The importance in lung cancer epidemiology of vitamin A deficiency, occupation and psychosocial stress was discussed, and some support was found for the role of psychosocial stress in both the migration and the marital status factors.


2004 ◽  
Vol 25 (4) ◽  
pp. 319-329 ◽  
Author(s):  
M. R. A. Pedro ◽  
J. R. Madriaga ◽  
C. V. C. Barba ◽  
R. C. F. Habito ◽  
A. E. Gana ◽  
...  

2005 ◽  
Vol 26 (4) ◽  
pp. 356-365 ◽  
Author(s):  
Constance P. Nana ◽  
Inge D. Brouwer ◽  
Noel-Marie Zagré ◽  
Frans J. Kok ◽  
Alfred S. Traoré

Background Vitamin A deficiency remains a public health problem in Burkina Faso and elsewhere in the developing world. Dietary diversification is a promising strategy that needs to be explored to strengthen the country's ongoing supplementation program. Objective The purpose of this study was to identify locally available and acceptable (pro)vitamin A–rich foods to be included in a dietary intervention addressing vitamin A deficiency in children aged six months to three years. Methods A food ethnographic study combining recall methods, observation, and focused group discussion was conducted in the dry and rainy seasons. Thirty-five mother–child pairs were randomly selected and included in the study. Results The dietary pattern of children was characterized by low diversity with extremely low energy and vitamin A intake in both seasons. The study identified the availability of numerous (pro)vitamin A–rich foods, but these foods are either not consumed or consumed by few in low amounts and/or in low frequencies. The main constraining factors identified are related to financial accessibility (for liver), seasonal availability (for egg, milk, mango, papaya, and green leafy vegetables), and beliefs related to consumption and preparation (for green leafy vegetables). However, the study also revealed that the study population associated all identified (pro)vitamin A–rich foods with positive attributes such as health, strength, and vitamin richness, which might offer an entry point for designing and implementing dietary interventions. Conclusions Based on the findings of this formative research, intervention strategies with mango and liver are proposed to improve the vitamin A intake and status of children in the rural areas of Burkina Faso.


2011 ◽  
Vol 81 (5) ◽  
pp. 295-305 ◽  
Author(s):  
John B. Mason ◽  
Maria A. Ramirez ◽  
Chona M. Fernandez ◽  
Regina Pedro ◽  
Tina Lloren ◽  
...  

Regular semi-annual distribution of high-dose (200,000 IU) vitamin A capsules (VACs) to children 1 - 5 years of age (previously identified as underweight), in Leyte Province, the Philippines, was compared to providing extra VACs to give three-monthly dosing, and to vitamin A-fortified cooking oil (VAFO) promotion (with continued VACs every 6 months). Serum retinol (SR) was measured at baseline and after 12 or 18 months (for VAFO). No sustained increase in SR was determined from the three-month VAC dosing regimen, and the prevalence of vitamin A deficiency (VAD) as assessed by SR (< 20 mcg / dL) remained around 30 % (in line with national survey estimates over the previous 15 years). The major difference found was that 18 months of VAFO (of which 9 months had sustained promotion) was associated with reducing the prevalence of VAD to < 10 %. The effective fortification and lack of effect of semi-annual VAC results are in line with previous studies; testing with dosing of VAC every three months is a new intervention. The results imply that promotion of fortified oil would reduce VAD in these conditions; whether it can replace or needs to be added to semi-annual VAC dosing remains to be determined. A phased changeover to reliance on fortified commodities (including oil) with careful monitoring of VAD trends is indicated.


2011 ◽  
Vol 15 (4) ◽  
pp. 568-577 ◽  
Author(s):  
Avula Laxmaiah ◽  
Madhavan K Nair ◽  
Nimmathota Arlappa ◽  
Pullakhandam Raghu ◽  
Nagalla Balakrishna ◽  
...  

AbstractObjectiveTo assess the magnitude and determinants of vitamin A deficiency (VAD) and coverage of vitamin A supplementation (VAS) among pre-school children.DesignA community-based cross-sectional study was carried out by adopting a multistage, stratified, random sampling procedure.SettingRural areas of eight states in India.SubjectsPre-school children and their mothers were covered.ResultsA total of 71 591 pre-school children were clinically examined for ocular signs of VAD. Serum retinol concentrations in dried blood spots were assessed in a sub-sample of 3954 children using HPLC. The prevalence of Bitot spots was 0·8 %. The total ocular signs were significantly higher (P < 0·001) among boys (2·6 %) compared with girls (1·9 %) and in older children (3–4 years) compared (P < 0·001) with younger (1–2 years), and were also high in children of labourers, scheduled castes and illiterate mothers. The odds of having Bitot spots was highest in children of scheduled caste (OR = 3·8; 95 % CI 2·9, 5·0), labourers (OR = 2·9; 95 % CI 2·1, 3·9), illiterate mothers (OR = 2·7; 95 % CI 2·2, 2·3) and households without a sanitary latrine (OR = 5·9; 95 % CI 4·0, 8·7). Subclinical VAD (serum retinol level <20 μg/dl) was observed in 62 % of children. This was also relatively high among scheduled caste and scheduled tribe children. The rate of coverage of VAS was 58 %.ConclusionsThe study revealed that VAD is a major nutritional problem and coverage of VAS was poor. The important determinants of VAD were illiteracy, low socio-economic status, occupation and poor sanitation. Strengthening the existing VAS programme and focused attention on dietary diversification are essential for prevention of VAD.


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