scholarly journals Dairy administration of Lactobacillus reuteri 263 suppresses body fat synthesis and alters the body composition on high fat diet induced obese SD rats

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Shu‐Ping Tsao ◽  
Yi‐Ting Lin ◽  
Hui‐Yu Huang
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
High Fat Diet ◽  
Lactobacillus Reuteri ◽  
The Body ◽  
High Fat ◽  
Sd Rats ◽  
Fat Synthesis

scholarly journals Evaluation of Anti-Obesity Activity, Acute Toxicity, and Subacute Toxicity of Probiotic Dark Tea

Biomolecules ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 99 ◽  
Author(s):  
Wang Ling ◽  
Shungeng Li ◽  
Xingcai Zhang ◽  
Yongquan Xu ◽  
Ying Gao ◽  
...  
Keyword(s):  
Body Weight ◽  
High Fat Diet ◽  
Metabolic Disorders ◽  
The Body ◽  
High Fat ◽  
Water Group ◽  
Subacute Toxicity ◽  
Infusion Group ◽  
Sd Rats ◽  
Group Ii

: Probiotic dark tea (PDT) is a novel kind of dark tea produced by fresh albino tea leaves and fermented with specific probiotics. Our study demonstrates that PDT can ameliorate high-fat diet-induced overweight and lipid metabolic disorders and shows no acute or subacute toxicity in Sprague-Dawley (SD) rats. Daily intragastric administration of 5% PDT infusion for 14 days caused no obvious effect on general physiological features and behaviors of rats. Oral administration of 1%, 2%, and 3% of PDT infusion for six weeks had no influence on the biochemistry and histopathology of rats’ organs and blood, as well as the body weight and ratios of organ/body weight. To investigate its anti-obesity activity, SD rats were randomly divided into four groups, treated with normal diet + water (Group I), high-fat diet + water (Group II), high-fat diet + 3% traditional dark tea infusion (Group III), high-fat diet + 3% PDT infusion (Group IV). After six weeks, the body weight, serum total triacylglycerol (TG) and serum total cholesterol (TC) levels of rats in Group II were significantly increased and the high-density lipoprotein cholesterol (HDL) levels were significantly decreased compared with those in the other three groups. Both traditional dark tea and PDT treatment effectively counteracted the adverse effect of a high-fat diet in SD rats. These results suggest that PDT could be applied for the prevention of obesity, which ameliorates overweight and lipid metabolic disorders and which shows no acute or subacute toxicity.

scholarly journals Regulation of the Body Fat Percentage in Developmental-Stage Rats by Methylxanthine Derivatives in a High-Fat Diet

2006 ◽  
Vol 70 (5) ◽  
pp. 1134-1139 ◽  
Author(s):  
Hiroko INOUE ◽  
Kazuo KOBAYASHI-HATTORI ◽  
Yumi HORIUCHI ◽  
Yuichi OISHI ◽  
Souichi ARAI ◽  
...  
Keyword(s):  
Developmental Stage ◽  
Body Fat ◽  
High Fat Diet ◽  
The Body ◽  
Body Fat Percentage ◽  
High Fat ◽  
Fat Percentage

scholarly journals Loss of Selenoprotein V Predisposes Mice to Body Fat Accumulation (OR11-02-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Lingli Chen ◽  
Jiaqiang Huang ◽  
Yuanyuan Wu ◽  
Fazheng Ren ◽  
Xin Gen Lei
Keyword(s):  
Gene Expression ◽  
Body Fat ◽  
High Fat Diet ◽  
The Body ◽  
High Fat ◽  
Fat Accumulation ◽  
Diet Induced Obesity ◽  
Body Weights ◽  
Its Gene ◽  
Selenoprotein V

Abstract Objectives Metabolic function of selenoprotein V (SELENOV) remains unknown, although we previously showed a strong correlation of its gene expression with the high-fat diet-induced obesity in pigs. This study was conducted to explore the role and mechanism of SELENOV in body fat metabolism. Methods We applied the CRISPR/Cas9 gene-targeting deletion to generate Selenovknockout (KO) mice (C57BL/6 J background). Male KO and their wild-type (WT) (8 weeks old, n = 10 per genotype by treatment group) were fed a normal diet (NF, 10% calories coming from fat) or a high-fat diet (HF, 60% calories coming from fat) for 27 weeks. At the end, body weights and composition of mice were recorded, and tissues were collected to assay for gene expression and protein production related to lipid metabolism. Results Body weights of the KO mice fed the NF or HF diet were 16–19% higher (P < 0.05) than those of the WT mice. Total fat mass of the KO mice was 54% higher (P < 0.05) than the WT mice fed either diet, whereas total lean mass of the KO mice was 5 and 35% lower (P < 0.05) than that of WT mice fed the NF and HF diets, respectively. Gene expression of key enzymes (Fasn, Acaca, Dgat1, and Lpl) involved in lipogenesis was elevated (P < 0.05) in the white adipose tissue of the KO mice compared with the WT mice. In contrast, differences in gene expression of enzymes related to lipolysis and fatty acid oxidation (Atgl, Hsl, Ces1d, and Cpt1a) between the two genotypes were exactly the opposite (P < 0.05). Consistently, levels of proteins related to lipid accumulation (pACC, ACC, FAS, and LPL) were upregulated (P < 0.05) and proteins related to lipolysis (ATGL, HSL, and pHSL) were down-regulated (P < 0.05) in the KO mice compared with the WT mice. Conclusions Knockout of Selenov predisposed the male mice to elevated lipogenesis and attenuated lipolyis, leading to the body fat accumulation. This illustrated role and mechanism of SELENOV helps explain our previously-reported correlation between its gene expression and the high-fat diet-induced obesity in pigs. Funding Sources This research was supported in part by a NSFC grant #31,320,103,920.

scholarly journals Strength Training Reduces Fat Accumulation and Improves Blood Lipid Profile Even in the Absence of Skeletal Muscle Hypertrophy in High-Fat Diet-Induced Obese Condition

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Catarina Denise Entringer Contreiro ◽  
Leonardo Carvalho Caldas ◽  
Breno Valentim Nogueira ◽  
André Soares Leopoldo ◽  
Ana Paula Lima-Leopoldo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Body Composition ◽  
Strength Training ◽  
High Fat Diet ◽  
Muscle Hypertrophy ◽  
The Body ◽  
High Fat ◽  
Metabolic Adaptations ◽  
Obese Rats ◽  
Training Protocol

The aim was to investigate the effect of strength training on skeletal muscle morphology and metabolic adaptations in obese rats fed with unsaturated high-fat diet (HFD). The hypothesis was that strength training induces positive metabolic adaptations in obese rats despite impaired muscle hypertrophy. Male Wistar rats (n = 58) were randomized into two groups and fed a standard diet or a high-fat diet (HFD) containing 49.2% of fat. After induction and maintenance to obesity, the rats were divided into four groups: animals distributed in sedentary control (CS), control submitted to strength training protocol (CT), obese sedentary (ObS), and obese submitted to strength training protocol (ObT). The exercise protocol consisted of 10 weeks of training on a vertical ladder (three times a week) with a load attached to the animal’s tail. At the end of 10 weeks, strength training promoted positive changes in the body composition and metabolic parameters in obese animals. Specifically, ObT animals presented a reduction of 22.6% and 14.3% in body fat and adiposity index when compared to ObS, respectively. Furthermore, these rats had lower levels of triglycerides (ObT = 23.1 ± 9.5 vs. ObS = 30.4 ± 6.9 mg/dL) and leptin (ObT = 13.2 ± 7.2 vs. ObS = 20.5 ± 4.3 ng/mL). Training (ObT and CT) induced a greater strength gain when compared with the respective control groups. In addition, the weight of the flexor hallucis longus (FHL) muscle was higher in the ObT group than in the CT group, representing an increase of 26.1%. However, training did not promote hypertrophy as observed by a similar cross-sectional area of the FHL and plantar muscles. Based on these results, high-intensity strength training promoted an improvement of body composition and metabolic profile in obese rats that were fed a high-fat diet without skeletal muscle adaptations, becoming a relevant complementary strategy for the treatment of obesity.

scholarly journals Daily physical activity and macronutrient distribution of low-calorie diets jointly affect body fat reduction in obese women

2009 ◽  
Vol 34 (4) ◽  
pp. 595-602 ◽  
Author(s):  
Constanza Matilde López-Fontana ◽  
Almudena Sánchez-Villegas ◽  
Miguel Angel Martínez-Gonzalez ◽  
José Alfredo Martinez
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Body Fat ◽  
High Fat Diet ◽  
Fat Distribution ◽  
Obese Women ◽  
High Fat ◽  
Low Fat ◽  
Low Fat Diet ◽  
Composition Changes

Inadequate dietary patterns and sedentary lifestyles are believed to be important factors in predisposing people to obesity. This study analyzed the potential interaction between habitual physical activity and the carbohydrate (CHO)-fat distribution in 2 hypocaloric diets and the impact of such interplay on body composition changes. Forty healthy obese women, 20–50 years old, were randomly assigned to a high- or low-CHO energy-restricted diet, which was low or high in fat, respectively, during 10 weeks. Baseline and final measurements were performed to assess dietary habits, resting metabolic rate, and body composition changes. Physical activity was measured with a triaxial accelerometer and with a questionnaire. There were no significant differences in anthropometric and metabolic variables between both dietary groups at baseline. However, there was a positive correlation between total free-living physical activity and arm muscle preservation after 10 weeks (r = 0.371; p = 0.024). Interestingly, an interaction between macronutrient (CHO–fat distribution) intake and physical activity was found, since less-active subjects with a high-CHO–low-fat diet showed a greater fat loss than those more active with a lower-CHO–high-fat diet, whereas more-active subjects with a high-CHO–low-fat diet showed a smaller fat loss than those receiving a low-CHO–high-fat diet. Physical activity and the macronutrient content of energy-restricted diets, when designed to promote body fat mass reduction, should be considered together to better predict the outcome.

Retarding effect of dietary fibers from bamboo shoot (Phyllostachys edulis) on hyperlipidemic rats induced by high-fat diet

2021 ◽  
Author(s):  
Qi Li ◽  
Xiangjun Fang ◽  
Hangjun Chen ◽  
Yanchao Han ◽  
Ruiling Liu ◽  
...  
Keyword(s):  
Body Weight ◽  
Dietary Fiber ◽  
High Fat Diet ◽  
The Body ◽  
Bamboo Shoot ◽  
Dietary Fibers ◽  
High Fat ◽  
Phyllostachys Edulis ◽  
Retarding Effect ◽  
Sd Rats

The effects of administration of bamboo shoot (Phyllostachys edulis) dietary fiber (BSDF) on high-fat diet (HDF) induced hyperlipidemia were studied with SD rats model. Results indicated that the body weight...

Effect of Caffeine on the Body Fat and Lipid Metabolism of Rats Fed on a High-Fat Diet

2005 ◽  
Vol 69 (11) ◽  
pp. 2219-2223 ◽  
Author(s):  
Kazuo KOBAYASHI-HATTORI ◽  
Akie MOGI ◽  
Yoshinobu MATSUMOTO ◽  
Toshichika TAKITA
Keyword(s):  
Lipid Metabolism ◽  
Body Fat ◽  
High Fat Diet ◽  
The Body ◽  
High Fat
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