A Randomized Controlled Trial of Calcium Supplementation to Reduce Blood Lead Levels (and Fetal Lead Exposure) in Pregnant Women

Epidemiology ◽  
2006 ◽  
Vol 17 (Suppl) ◽  
pp. S123
Author(s):  
M Téllez-Rojo ◽  
H Lamadrid-Figueroa ◽  
A Mercado-García ◽  
K Peterson ◽  
D Bellinger ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Pregnant Women ◽  
Lead Exposure ◽  
Calcium Supplementation ◽  
Controlled Trial ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Randomized Controlled ◽  
Lead Levels

scholarly journals Assessment of a Screening Questionnaire to Identify Exposure to Lead in Pregnant Women

2020 ◽  
Vol 17 (24) ◽  
pp. 9220
Author(s):  
Eléna Coiplet ◽  
Marine Freuchet ◽  
Claire Sunyach ◽  
Julien Mancini ◽  
Jeanne Perrin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Cross Sectional ◽  
Lead Levels ◽  
Risk Of Exposure ◽  
Exposure During Pregnancy ◽  
Systematic Identification

Lead readily crosses the placenta and displays adverse effects on birth outcomes and neurodevelopment. Systematic identification of the risk of exposure during pregnancy is essential but rarely performed, probably due to hospital staff’s workload and their lack of awareness. We aimed to evaluate the relevance of a questionnaire to screen pregnant women for lead exposure. A cross-sectional, multicentre study was carried out on a population of 792 pregnant women from February 2018 to May 2020. A total of 596 women had a blood lead test: 68.5% had blood lead levels below 10 μg/L. The estimated prevalence above 25 µg/L was 4% (95% confidence interval (CI) [2.6–5.9]) and 1.3% had levels above 50 µg/L (95% CI [0.6–2.6]). Multivariate analysis showed that three risk factors significantly increased the probability of blood lead levels above 25 µg/L: the use of traditional cosmetics (adjusted odds ratio [aOR]: 3.90; 95% CI [1.65–9.21]; p = 0.002), degraded old housing (aOR: 2.67; 95% CI [1.19–6.038]; p = 0.018), and (marginally) eating bread more than twice a day (aOR: 2.40; 95% CI [0.96–6.11]; p = 0.060). Our study reveals that a three-question tool can be used to quickly screen for the risk of lead exposure in our population and to trigger lead blood tests and special vigilance during pregnancy follow-up.

scholarly journals Blood lead levels and risk factors for lead exposure among pregnant women in western French Guiana: the role of manioc consumption

2017 ◽  
Vol 80 (6) ◽  
pp. 382-393 ◽  
Author(s):  
Diane Rimbaud ◽  
Marion Restrepo ◽  
Anne Louison ◽  
Rachida Boukhari ◽  
Vanessa Ardillon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Lead Exposure ◽  
French Guiana ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Lead Levels

scholarly journals Blood Lead Levels in Pregnant Women and the Source of Exposure in Northern Coastal Area of Brebes Regency

2018 ◽  
Vol 1 (1) ◽  
pp. 6-12
Author(s):  
Nova Amalia Sakina ◽  
Suhartono Suhartono ◽  
Nikie Astorina Yunita Dewanti
Keyword(s):  
Pregnant Women ◽  
Lead Exposure ◽  
Passive Smoking ◽  
Blood Lead ◽  
Quality Standard ◽  
Cross Sectional Study ◽  
Blood Lead Levels ◽  
Agricultural Activity ◽  
Cross Sectional ◽  
Lead Levels

Background: Lead has no advantage for health, pregnant women are vulnerable to lead exposure. Blood Lead Levels (BLLs) in pregnant women that exceed the quality standard in accordance with Center for Disease Control (CDC) (>5 μg/dL) can encounter spontaneous miscarriage and fatigue easily during pregnancy, BLLs in pregnant women < 10 μg/dL can induce health problem during pregnancy such as hypertension, preeclampsia, and eclampsia which is the cause of mortality in pregnant women and high maternal mortality. The aim of study to measure BBLs and the source of exposure.Methods: Pregnant women in 2nd and 3rd trimester were recruited in 4 Subdistricts. Cross sectional study is used with 86 pregnant women located in Wanasari Subdistrict, Bulakamba Subdistrict, Losari Subdistrict and Tanjung Subdistrict with purposive sampling method. BLLs during pregnancy were determined by Atomic Adsorpiton Spectrometer.Results: The results shows that mean of BLLs in pregnant women in this study were 42.437 + 19.758 μg/dL. The source of lead exposure are the habit of consuming seafood (44.2%), wrapping food using newspaper (80.2%), being involve in agricultural activity (37.2%), and passive smoking (70.9%).Conclusions: To recapitulate, BBLs in pregnant women in the northern area of Brebes Regency have exceeded the standard set by the CDC of 5 μg/dL. The dominant source of lead exposure are the habit of wrapping food using newspaper and passive smoking.

scholarly journals Effect of Calcium Supplementation on Blood Lead Levels in Pregnancy: A Randomized Placebo-Controlled Trial

2009 ◽  
Vol 117 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Adrienne S. Ettinger ◽  
Héctor Lamadrid-Figueroa ◽  
Martha M. Téllez-Rojo ◽  
Adriana Mercado-García ◽  
Karen E. Peterson ◽  
...  
Keyword(s):  
Calcium Supplementation ◽  
Controlled Trial ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Lead Levels ◽  
In Pregnancy

scholarly journals Blood lead level and risk of hypertension in the United States National Health and Nutrition Examination Survey 1999–2016

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Man Fung Tsoi ◽  
Chris Wai Hang Lo ◽  
Tommy Tsang Cheung ◽  
Bernard Man Yung Cheung
Keyword(s):  
Blood Pressure ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
The United States ◽  
Study Data ◽  
Blood Lead Levels ◽  
Environmental Lead ◽  
Lead Levels

AbstractLead is a heavy metal without a biological role. High level of lead exposure is known to be associated with hypertension, but the risk at low levels of exposure is uncertain. In this study, data from US NHANES 1999–2016 were analyzed. Adults with blood lead and blood pressure measurements, or self-reported hypertension diagnosis, were included. If not already diagnosed, hypertension was defined according to the AHA/ACC 2017 hypertension guideline. Results were analyzed using R statistics version 3.5.1 with sample weight adjustment. Logistic regression was used to study the association between blood lead level and hypertension. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated. Altogether, 39,477 participants were included. Every doubling in blood lead level was associated with hypertension (OR [95%CI] 1.45 [1.40–1.50]), which remained significant after adjusting for demographics. Using quartile 1 as reference, higher blood lead levels were associated with increased adjusted odds of hypertension (Quartile 4 vs. Quartile 1: 1.22 [1.09–1.36]; Quartile 3 vs. Quartile 1: 1.15 [1.04–1.28]; Quartile 2 vs. Quartile 1: 1.14 [1.05–1.25]). In conclusion, blood lead level is associated with hypertension in the general population with blood lead levels below 5 µg/dL. Our findings suggest that reducing present levels of environmental lead exposure may bring cardiovascular benefits by reducing blood pressure.

Low-Level Lead Exposure and Blood Lead Levels in Children: A Cross-Sectional Survey

2001 ◽  
Vol 56 (6) ◽  
pp. 501-505 ◽  
Author(s):  
Aysha Habib Khan ◽  
Amanullah Khan ◽  
Farooq Ghani ◽  
Muhammad Khurshid
Keyword(s):  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Low Level ◽  
Lead Levels
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