MULTIPLE FREQUENCY BIOIMPEDANCE PREDICTS EXTRACELLULAR WATER BUT NOT TOTAL BODY WATER BETTER THAN SINGLE FREQUENCY BIOIMPEDANCE IN POST SURGICAL CRITICALLY ILL PATIENTS

1995 ◽  
Vol 23 (Supplement) ◽  
pp. A27 ◽  
Author(s):  
Rakesh Patel ◽  
Norman Silverman ◽  
Barbara Zarowitz
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Total Body Water ◽  
Body Water ◽  
Single Frequency ◽  
Extracellular Water ◽  
Multiple Frequency ◽  
Total Body ◽  
Better Than

BODY WATER COMPARTMENTS IN THE PREMATURE INFANT, WITH SPECIAL REFERENCE TO THE EFFECTS OF THE RESPIRATORY DISTRESS SYNDROME AND OF MATERNAL DIABETES AND TOXEMIA

PEDIATRICS ◽  
1962 ◽  
Vol 29 (6) ◽  
pp. 883-889
Author(s):  
Wesley M. Clapp ◽  
L. Joseph Butterfield ◽  
Donough O'Brien
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Total Body Water ◽  
Distress Syndrome ◽  
Body Water ◽  
Control Group ◽  
Extracellular Water ◽  
Water Compartments ◽  
Significant Difference ◽  
Total Body

Normal values for both total body water and extracellular water have been determined in 86 premature infants aged 1 to 90 days and weighing 940 to 2,435 gm, with use of the techniques of deuterium oxide and bromide dilution. Nine full-term infants aged 1 to 6 days and weighing 2,590 to 4,985 gm were similarly studied. Nine infants with the respiratory distress syndrome and eight infants of toxemic mothers studied in the first 24 hours of life showed no significant difference in their body water compartments in comparison to a control group of normal infants matched for age and weight. Seven infants of diabetic mothers studied in the first 24 hours of life showed a significant decrease in total body water, expressed as percentage of body weight, with a normal intracellular to extracellular water ratio. These data indirectly support other evidence that there is an increase in body fat in these infants at birth. See Table in the PDF file

Analytic assessment of the various bioimpedance methods used to estimate body water

1998 ◽  
Vol 84 (5) ◽  
pp. 1801-1816 ◽  
Author(s):  
J. Matthie ◽  
B. Zarowitz ◽  
A. De Lorenzo ◽  
A. Andreoli ◽  
K. Katzarski ◽  
...  
Keyword(s):  
Body Water ◽  
Intracellular Water ◽  
Single Frequency ◽  
Fluid Distribution ◽  
Good Prediction ◽  
Extracellular Water ◽  
Tissue Change ◽  
Water Compartments ◽  
Water Conduction ◽  
Total Body

Knowledge of patient fluid distribution would be useful clinically. Both single-frequency (SF) and impedance modeling approaches are proposed. The high intercorrelation between body water compartments makes determining the best approach difficult. This study was conducted to evaluate the merits of an SF approach. Mathematical simulation was performed to determine the effect of tissue change on resistance and reactance. Dilution results were reanalyzed, and resistance and parallel reactance were used to predict the intracellular water for two groups. Results indicated that the amount of intracellular and extracellular water conduction at any SF can vary with tissue change, and reactance at any SF is affected by all tissue parameters. Modeling provided a good prediction of dilution intracellular and extracellular water, but an SF method did not. Intracellular, extracellular, and total body water were equally predicted at all frequencies by SF resistance and parallel reactance. Extracellular and intracellular water are best measured through modeling, because only at the zero and infinite frequencies are the results sensitive only to extracellular and intracellular water. At all other frequencies there are other effects.

scholarly journals Rapid Weight Loss and the Body Fluid Balance and Hemoglobin Mass of Elite Amateur Boxers

2013 ◽  
Vol 48 (1) ◽  
pp. 109-117 ◽  
Author(s):  
Dejan Reljic ◽  
Eike Hässler ◽  
Joachim Jost ◽  
Birgit Friedmann-Bette
Keyword(s):  
Blood Volume ◽  
Body Mass ◽  
Plasma Volume ◽  
Total Body Water ◽  
Real Life ◽  
Body Water ◽  
Extracellular Water ◽  
Real Life Setting ◽  
Total Body ◽  
Hemoglobin Mass

Context Dehydration is assumed to be a major adverse effect associated with rapid loss of body mass for competing in a lower weight class in combat sports. However, the effects of such weight cutting on body fluid balance in a real-life setting are unknown. Objective To examine the effects of 5% or greater loss of body mass within a few days before competition on body water, blood volume, and plasma volume in elite amateur boxers. Design Case-control study. Setting Sports medicine laboratory. Patients or Other Participants Seventeen male boxers (age = 19.2 ± 2.9 years, height = 175.1 ± 7.0 cm, mass = 65.6 ± 9.2 kg) were assigned to the weight-loss group (WLG; n = 10) or the control group (CON; n = 7). Intervention(s) The WLG reduced body mass by restricting fluid and food and inducing excessive sweat loss by adhering to individual methods. The CON participated in their usual precompetition training. Main Outcome Measure(s) During an ordinary training period (t-1), 2 days before competition (t-2), and 1 week after competition (t-3), we performed bioelectrical impedance measurements; calculated total body water, intracellular water, and extracellular water; and estimated total hemoglobin mass (tHbmass), blood volume, and plasma volume by the CO-rebreathing method. Results In the WLG, the loss of body mass (5.6% ± 1.7%) led to decreases in total body water (6.0% ± 0.9%), extracellular water (12.4% ± 7.6%), tHbmass (5.3% ± 3.8%), blood volume (7.6% ± 2.1%; P < .001), and plasma volume (8.6% ± 3.9%). The intracellular water did not change (P > .05). At t-3, total body water, extracellular water, and plasma volume had returned to near baseline values, but tHbmass and blood volume still were less than baseline values (P < .05). In CON, we found no changes (P > .05). Conclusions In a real-life setting, the loss of approximately 6% body mass within 5 days induced hypohydration, which became evident by the decreases in body water and plasma volume. The reduction in tHbmass was a surprising observation that needs further investigation.

BODY WATER COMPARTMENTS IN CHILDREN: CHANGES DURING GROWTH AND RELATED CHANGES IN BODY COMPOSITION

PEDIATRICS ◽  
1961 ◽  
Vol 28 (2) ◽  
pp. 169-181
Author(s):  
B. Friis-Hansen
Keyword(s):  
Body Composition ◽  
Total Body Water ◽  
Rapid Decrease ◽  
Body Water ◽  
The Other ◽  
First Year ◽  
Extracellular Water ◽  
Water Compartments ◽  
Total Body ◽  
First Year Of Life

During growth of infants and children, certain characteristic changes are found. A rapid decrease of the relative volumes of total body water and of extracellular water occurs during the first year of life, followed by a smaller decrease of volume of extracellular water later in childhood. At the same time an increased heterogeneity of the extracellular water takes place. On the other hand, the volume of intracellular water increases a little during the first months of life and remains more or less constant from then on. Formulas and nomograms from which these body water compartments can be predicted are presented. Finally, data on the corresponding changes in the total body water and in body specific gravity are discussed.

Estimation of Total Body and Extracellular Water Using Single-and Multiple-Frequency Bioimpedance

1994 ◽  
Vol 28 (5) ◽  
pp. 565-569 ◽  
Author(s):  
Rakesh V. Patel ◽  
James R. Matthie ◽  
Paul O. Withers ◽  
Edward L. Peterson ◽  
Barbara J. Zarowitz
Keyword(s):  
Deuterium Oxide ◽  
Acute Care Hospital ◽  
Single Frequency ◽  
Care Hospital ◽  
Extracellular Water ◽  
Multiple Frequency ◽  
Open Label ◽  
For Profit ◽  
The Mean ◽  
Total Body

OBJECTIVE: To determine the precision and bias of single- and multiple-frequency bioimpedance estimates of total body water (TBW) and extracellular water (ECW) volumes in comparison with the true values for these volumes established by gold standard dilution techniques. DESIGN: Controlled, prospective, open-label investigation. SETTING: Private, not-for-profit university-affiliated, acute care hospital. PARTICIPANTS: Normal, healthy men (n=8) and women (n=6) volunteers, 25–46 years of age. INTERVENTIONS: A single oral dose of a mixture of deuterium oxide 10 g and bromine 30 mmol; bioimpedance analysis pre- and three hours postrnixture administration. MAIN OUTCOME PARAMETERS: TBW and ECW volumes established by deuterium oxide and bromine dilutional spaces (gold standards), respectively, and single- and multiple-frequency bioimpedance estimates of those same volumes. RESULTS: The mean multiple-frequency bioimpedance (MFB) and single frequency bioimpedance (SFB) estimates of TBW, 41.2 and 42.1 L, respectively, were not statistically different (NS) from the 41.2 L deuterium oxide value. Although the two methods had similar precision (NS), MFB was less biased. For ECW, the mean MFB and SFB values of 19.5 and 24.8 L, respectively, were significantly different from the bromine value of 18.8 L (p=0.013 and p=0.001, respectively). MFB was the more precise and less biased predictor of ECW. CONCLUSIONS: Compared with SFB, the MFB approach is a more precise and less biased predictor of TBW and ECW volumes in young, healthy adults, and may offer more accurate assessment in subjects with aberrant physiology.

scholarly journals Can Bioimpedance Determine the Volume of Distribution of Antibiotics in Sepsis?

2005 ◽  
Vol 33 (3) ◽  
pp. 345-350 ◽  
Author(s):  
M. Balik ◽  
J. Sedivy ◽  
P. Waldauf ◽  
M. Kolar ◽  
V. Smejkalova ◽  
...  
Keyword(s):  
Fluid Balance ◽  
Total Body Water ◽  
Volume Of Distribution ◽  
Body Water ◽  
University Hospital ◽  
Pharmacokinetic Analysis ◽  
Extracellular Water ◽  
Serum Concentrations ◽  
Total Body ◽  
Volumes Of Distribution

The relationship between the volume of distribution, assessed according to the two-compartmental pharmacokinetic model, and extracellular water estimated by bioimpedance was studied in mechanically ventilated patients with sepsis and capillary leak. A prospective observational study was performed in a twenty-bed general intensive care unit in the university hospital. Patients received either vancomycin (n=16) or netilmicin (n=12) for more than 48 hours. Those with ascites, pleural effusion, on renal replacement therapy or with haemodynamic instability were excluded. Serum concentrations of drugs were taken for pharmacokinetic analysis before, 1 hour and 4 hours after the 30 minute infusion. Bioimpedance measurement was performed at the time of the third sampling. The protocol was repeated after 24 hours. Fluid balance during the 24 hour interval was recorded. Extracellular water was increased and represented 45.6 to 46.6% of total body water. Fluid balance correlated with the change of extracellular water (r=0.82, P<0.0001) and total body water (r=0.74, P<0.0001). Volumes of distribution of vancomycin (0.677±0.339 l/kg) and netilmicin (0.505±0.172 l/kg) were increased compared to normal values. A correlation was demonstrated between volume of distribution (Vdarea) of vancomycin and extra cellular water/total body ratio (r=0.70, P<0.0001). The central compartment distribution volume (V1) of netilmicin correlated with extracellular water/total body water ratio (r=0.60, P<0.003). Serum concentrations above the recommended therapeutic range were detected in 81.2% of patients on vancomycin and in 50% of patients on netilmicin. Increased volumes of distribution can be estimated by the bioimpedance measurements but are not associated with requirements for higher dosage of the glycopeptide or aminoglycoside antibiotics.

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