IMPROVEMENT IN FUNCTIONAL CAPACITY AND QUALITY OF LIFE FOLLOWING PARTICIPATION IN A NON-TRADITIONAL CARDIOPULMONARY REHABILITATION PROGRAM IN PATIENTS WITH SEVERE HEART FAILURE. 12

Abstract Sleep disorders are very common in patients with heart disease. The objective of this study has been to assess the effects of a cardiac rehabilitation program on sleep quality, quality of life, anxiety, depression and functional capacity in patients with heart disease. A pre-test/post-test design study was carried out on the 240 patients included in the cardiac rehabilitation program at the “Virgen de la Victoria” hospital in Malaga; 50 patients (20.8%) were included in the program due to heart failure (HF) and the rest of them after having undergone a revascularization procedure or a surgery for valvular disease. The patients underwent a cardiac rehabilitation program for 8 weeks, based on programmed physical training, health education and psychological treatment. At the end of the program, scores improved on the Pittsburgh Sleep Quality Index (p = 0.008), the SF-36 Quality of Life Questionnaire (p <0.001), the Goldberg Anxiety and Depression Scale (p <0.001) as well as in functional capacity (p <0.001). When comparing patients with heart failure with those without, no differences were found in sleep quality, quality of life, anxiety or depression. In conclusion, the completion of an 8-week cardiac rehabilitation program may improve, in the short term, the quality of sleep in patients with heart disease.

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Quality of life in heart failure with preserved ejection fraction: importance of obesity, functional capacity, and physical inactivity

European Journal of Heart Failure ◽

10.1002/ejhf.1788 ◽

2020 ◽

Vol 22 (6) ◽

pp. 1009-1018 ◽

Cited By ~ 7

Author(s):

Yogesh N.V. Reddy ◽

Aruna Rikhi ◽

Masaru Obokata ◽

Sanjiv J. Shah ◽

Gregory D. Lewis ◽

...

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Ejection Fraction ◽

Functional Capacity ◽

Physical Inactivity ◽

Preserved Ejection Fraction

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Abstract 15830: Elevated Resting Heart Rate is Associated With Impaired Quality of Life and Worse NYHA Functional Capacity in Patients With Chronic Heart Failure: Results From REALITY HF Study

Circulation ◽

10.1161/circ.130.suppl_2.15830 ◽

2014 ◽

Vol 130 (suppl_2) ◽

Author(s):

Yuksel Cavusoglu ◽

Omer Kozan ◽

Ahmet Temizhan ◽

Serdar Kucukoglu

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Heart Rate ◽

Functional Capacity ◽

Real Life ◽

Left Ventricular ◽

Summary Score ◽

Treatment Modalities ◽

Resting Heart Rate

Purpose: Resting heart rate (HR), health related quality of life (HQoL) and NYHA functional capacity are referred as important determinants of prognosis and targets of therapy in heart failure (HF). REALITY HF (Resting Heart Rate and Real Life Treatment Modality in Outpatients with Left Ventricular Systolic Dysfunction) study data were analyzed for the evaluation of any relationship of resting HR with HQoL assessed by Kansas City Cardiomyopathy Questionnaire (KCCQ) and NYHA functional class. Methods: REALITY HF was a multicenter, prospective registry designed to evaluate HF patients’ characteristics and effects of treatment modalities on resting HR and enrolled 1057 patients (age 61±12 years) with LVEF <40%. 781 (74%) patients in sinus rhythm were included in this analysis. Patients were classified into 4 groups according to the quartiles of HR: Q1:<68 bpm (n=234), Q2:69-75 bpm (n=189), Q3:76-87 bpm (n=194) and Q4:>87 bpm (n=164). KCCQ was completed in a random sample of 320 (Q1:n=27, Q2:n=99, Q3:n=125, Q4:n=69) patients, in which higher scores show better patient’s health status. Results: During enrollment, 82% of patients were receiving ≥2 drugs including ACE[[Unable to Display Character: İ]]/ARB, beta blocker, aldosterone blocker, diuretic or digoxin. Resting HR was 76±14 bpm and 68% of patients had a resting HR ≥70 bpm. KCCQ overall summary score (OSC) was found to be 75.7±13.2 in those in Q1, 65.5±20.8 in Q2, 64.4±20.6 in Q3 and 58.3±21.2 in Q4 (p=0.004) and KCCQ clinical summary score (CSS) was 80.4±15.7 in those in Q1, 70.0±22.4 in Q2, 69.9±21.9 in Q3 and 63.8±23.3 in Q4 (p=0.016). Also, there was a significant negative correlation between resting HR and OSC (p=0.008) or CSS (p=0.031). The distribution of NYHA-I patients for Q1, Q2, Q3 and Q4 were 40.7%, 22.8%, 23.8% and 12.7%, NYHA-II patients-30.8%, 23.1%, 27.2% and 18.9%, NYHA-III patients-21.2%, 23.9%, 24.3% and 30.6% and NYHA-IV patients-22.7%, 34.1%, 22.7% and 20.5%, respectively (p<0.001). Also, resting HR were found to gradually and significantly increase across NYHA categories (72.8±12 bpm in NYHA-I, 76.1±13 bpm in NYHA-II, 80.2±15 bpm in NYHA-III and 78.9±16 bpm in NYHA-IV, p<0.001). Conclusions: These results suggest that elevated resting HR in HF patients is associated with impaired HQoL and worse NYHA functional capacity.

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SUPPORTING DEVICES IN THE TREATMENT OF CHRONIC HEART FAILURE IN ELDERLY AND OLD PATIENTS

Pharmacy Formulas ◽

10.17816/phf41944 ◽

2020 ◽

Vol 2 (3) ◽

pp. 40-57

Author(s):

Gennadiy Hubulava ◽

Kirill L. Kozlov ◽

Andrey N. Bogomolov ◽

Aleksey Volkov ◽

Viktor N. Fedorets ◽

...

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Clinical Practice ◽

Chronic Heart Failure ◽

Severe Heart Failure ◽

Circulatory Support ◽

Old Patients ◽

Western Countries ◽

Surgical Methods

Chronic heart failure (CHF) is a widespread disease associated with high rates of disability and mortality, as well as a decrease in the quality of life. Moreover, the vast majority of patients are elderly and senile. Modern surgical methods of treating heart failure are able to increase the duration and quality of life of such patients, however, the need far exceeds the volume of this care, and some highly effective methods common in Western countries are still not used in Russian clinical practice. Elderly age is a risk factor for the development of senile asthenia (frailty) and concomitant pathology. Large abdominal surgery is often contraindicated for patients with signs of senile asthenia, and the method of choice in patients with severe heart failure is the implantation of devices for long-term mechanical circulatory support (LT-MCS). After implantation of LT-MCS, a regression of signs of senile asthenia may be observed. The topic of an integrated approach to non-drug treatment of heart failure in elderly and senile patients in Russia has not been studied enough. In particular, the implantation of LT-MCS is not used in Russian clinical practice, while in many Western countries for many years it has been the main and most effective treatment for severe heart failure. Systematization of the available up-to-date information on this topic could help increase the duration and quality of life of patients with severe heart failure.

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Yoga for improving functional capacity, quality of life and cardiovascular outcomes in people with heart failure

Cochrane Database of Systematic Reviews ◽

10.1002/14651858.cd012015.pub2 ◽

2017 ◽

Author(s):

Mahalaqua Nazli Khatib ◽

Richard Kirubakaran ◽

Shilpa Gaidhane ◽

Anuraj H Shankar ◽

Zahiruddin Quazi Syed

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Functional Capacity ◽

Cardiovascular Outcomes

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Questionnaire for Severe Heart Failure (QLQ-SHF), Quality of Life

Encyclopedia of Quality of Life and Well-Being Research ◽

10.1007/978-94-007-0753-5_103379 ◽

2014 ◽

pp. 5382-5382

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Severe Heart Failure

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Effects of Oral Amino Acid Supplements on Functional Capacity in Patients with Chronic Heart Failure

Clinical Medicine Insights Cardiology ◽

10.4137/cmc.s14016 ◽

2014 ◽

Vol 8 ◽

pp. CMC.S14016 ◽

Cited By ~ 17

Author(s):

Carlo Lombardi ◽

Valentina Carubelli ◽

Valentina Lazzarini ◽

Enrico Vizzardi ◽

Filippo Quinzani ◽

...

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

New York ◽

Functional Capacity ◽

Exercise Tolerance ◽

Stress Test ◽

Nyha Class ◽

Heart Association

Amino acids (AAs) availability is reduced in patients with heart failure (HF) leading to abnormalities in cardiac and skeletal muscle metabolism, and eventually to a reduction in functional capacity and quality of life. In this study, we investigate the effects of oral supplementation with essential and semi-essential AAs for three months in patients with stable chronic HF. The primary endpoints were the effects of AA's supplementation on exercise tolerance (evaluated by cardiopulmonary stress test and six minutes walking test (6MWT)), whether the secondary endpoints were change in quality of life (evaluated by Minnesota Living with Heart Failure Questionnaire—MLHFQJ and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels. We enrolled 13 patients with chronic stable HF on optimal therapy, symptomatic in New York Heart Association (NYHA) class II/III, with an ejection fraction (EF) <45%. The mean age was 59 ± 14 years, and 11 (84.6%) patients were male. After three months, peak VO2 (baseline 14.8 ± 3.9 mL/minute/kg vs follow-up 16.8 ± 5.1 mL/minute/kg; P = 0.008) and VO2 at anaerobic threshold improved significantly (baseline 9.0 ± 3.8 mL/minute/kg vs follow-up 12.4 ± 3.9 mL/minute/kg; P = 0.002), as the 6MWT distance (baseline 439.1 ± 64.3 m vs follow-up 474.2 ± 89.0 m; P = 0.006). However, the quality of life did not change significantly (baseline 21 ± 14 vs follow-up 25 ± 13; P = 0.321). A non-significant trend in the reduction of NT-proBNP levels was observed (baseline 1502 ± 1900 ng/L vs follow-up 1040 ± 1345 ng/L; P = 0.052). AAs treatment resulted safe and was well tolerated by all patients. In our study, AAs supplementation in patients with chronic HF improved exercise tolerance but did not change quality of life.

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Effects of the combination of metformin and exercise on glycated hemoglobin, functional capacity, lipid profile, quality of life, and body weight

Journal of International Medical Research ◽

10.1177/0300060518817164 ◽

2019 ◽

Vol 47 (3) ◽

pp. 1131-1145 ◽

Cited By ~ 3

Author(s):

Sherif Eltonsy ◽

Monique Dufour Doiron ◽

Patrice Simard ◽

Caroline Jose ◽

Martin Sénéchal ◽

...

Keyword(s):

Quality Of Life ◽

Lipid Profile ◽

Functional Capacity ◽

Glycated Hemoglobin ◽

Rehabilitation Program ◽

Directed Acyclic Graphs ◽

Secondary Outcomes ◽

6 Minute Walk Test ◽

The Impact

Objective To evaluate the impact of the combination of metformin and exercise on changes in glycated hemoglobin (HbA1c), functional capacity, the lipid profile, quality of life, and weight. Methods Data from a 12-week cardiovascular rehabilitation program (2014–2016) were retrospectively evaluated. Metformin exposure was determined through recorded prescriptions, and average minutes of exercise per week were computed from exercise logs. The primary outcomes were changes in HbA1c and functional capacity (6-minute walk test [6MWT]) over 12 weeks. The secondary outcomes were changes in the lipid profile, quality of life, and weight. Directed acyclic graphs were used to identify potential confounders, accounted for with multiple linear regression. Results The cohort comprised 403 patients (85 metformin users, 318 non-users). The average amount of exercise was 102.7±48.7 minutes/week among metformin users and 107.7±58.1 minutes/week among non-users. Although changes in HbA1c were similar for both groups, the coefficient for the metformin–exercise interaction indicated significantly greater improvements in the 6MWT among metformin users. There were no between-group differences in any secondary outcomes. Conclusions The combination of metformin and exercise led to greater gains in functional capacity than exercise alone. This combination did not appear to influence the effects of either treatment on other outcomes.

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