Do combined oral contraceptive pills affect serum alkaline phosphatase level and bone mineral density?

2014 ◽  
Vol 4 (3) ◽  
pp. 164-167
Author(s):  
Mohamed H. Awad ◽  
Sahar M. Mansour ◽  
Reham M. Abbas
Keyword(s):  
Bone Mineral Density ◽  
Alkaline Phosphatase ◽  
Oral Contraceptive ◽  
Alkaline Phosphatase Level ◽  
Serum Alkaline Phosphatase ◽  
Serum Alkaline Phosphatase Level ◽  
Mineral Density ◽  
Oral Contraceptive Pills ◽  
Combined Oral Contraceptive ◽  
Contraceptive Pills

SUBACUTE THYROIDITIS WITH ELEVATED SERUM ALKALINE PHOSPHATASE LEVEL

1960 ◽  
Vol XXXIV (II) ◽  
pp. 256-260
Author(s):  
Jörgen Herman Vogt
Keyword(s):  
Alkaline Phosphatase ◽  
Alkaline Phosphatase Level ◽  
Serum Alkaline Phosphatase ◽  
Thyroid Tissue ◽  
Elevated Serum ◽  
Subacute Thyroiditis ◽  
Serum Alkaline Phosphatase Level ◽  
Transient Rise

ABSTRACT A case of subacute thyroiditis is recorded, in which a transient rise in serum alkaline phosphatase values leads to the hypothesis of a transient parathyroid hyper-activity induced by the inflammation of the thyroid tissue in which the parathyroid may be embedded.

scholarly journals Comparative study of ormeloxifene and low dose oral contraceptive pill for the treatment of dysfunctional uterine bleeding in peri-menopausal age group

2021 ◽  
Vol 10 (8) ◽  
pp. 3112
Author(s):  
Maitri Shah ◽  
Chirayu Parmar ◽  
Riddhi Gor
Keyword(s):  
Oral Contraceptive ◽  
Blood Loss ◽  
Uterine Bleeding ◽  
T Test ◽  
Wilcoxon Test ◽  
Age Group ◽  
Dysfunctional Uterine Bleeding ◽  
Oral Contraceptive Pills ◽  
Combined Oral Contraceptive ◽  
Contraceptive Pills

Background: Dysfunctional uterine bleeding (DUB) is the most common menstrual disorder of women in any age group and is a diagnosis of exclusion. Medical management of menorrhagia is a difficult task as there are wide variations in the available drugs and a lot of different regimes are available. Present study evaluates efficacy and safety of ormeloxifene a selective estrogen receptor modulator (SERMs) as compared to combined oral contraceptive pills in treatment of dysfunctional uterine bleeding in perimenopausal women.Methods: Total 60 patients meeting with our inclusion and exclusion criteria were enrolled in the study over a time period of 6 months and were further divided randomly into two groups. One group was given Ormeloxifene and the other group was treated with combined oral contraceptive pills (COCP) over a period of six months. The outcome variables noted were pictorial blood loss assessment chart (PBAC) score, Hb level and combined endometrial thickness (CET). Quantitative variables were compared using independent t test/Mann-Whitney test between the two groups and paired t Test/Wilcoxon test was used for comparison between pre and post within the group.Results: Both ormeloxifene and COCP significantly reduce blood loss in these patients evidenced by decrease of PBAC score, rise in hemoglobin levels and decrease in CET levels. However, ormeloxifene was found to be superior to COCP in reducing the menstrual blood loss. Ormeloxifene was also tolerated better compared to COCP with fewer side effects experienced by patients.

scholarly journals Histological changes of uterus after comparative treatment of female rats by Trigonella foenum-graecum seeds and combined oral contraceptive pills

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Ahmed Kaid Naji Allow ◽  
Ayah Rebhi Hilles ◽  
Zainab Yousef ◽  
Norbaiyah Mohamed Bakrim ◽  
Belqees Ahmed ◽  
...  
Keyword(s):  
Body Weight ◽  
Oral Contraceptive ◽  
Treated Group ◽  
Sprague Dawley ◽  
Histological Changes ◽  
Fenugreek Seeds ◽  
Oral Contraceptive Pills ◽  
Trigonella Foenum Graecum ◽  
Combined Oral Contraceptive ◽  
Contraceptive Pills

Introduction: This study evaluates the histological changes of uterine tissue in the female Sprague Dawley rats after administration of Trigonella foenum-graecum (fenugreek) seeds in comparison to combined oral contraceptive pills (COCPs). Methods: Twenty four female Sprague Dawley strain rats of 8 weeks old were divided into A, B, and C groups. Group A was the control and B was administrated with 0.05 mg/kg body weight of COCPs for 15 days. Group C was treated with 750 mg/kg body weight of fenugreek seed aqueous (FSA) extract for 15 days. The uterine tissues were isolated and studied histologically. Results: The uterine weight in the FSA extract treated group was normal, while in the COCPs treated group it was insignificantly increased. The endometrial thickness and endometrial gland density were normal in the FSA extract treated group, while in the COCPs treated group it was atrophied. Decidual-like cells were observed in the COCPs treated group only. Conclusions: Endometrial atrophy and decidual-like cells were noted after COCPs treatment while in the FSA extract and control groups they were absent. The findings suggest that fenugreek seeds could be used as an alternative natural and safe contraceptive product.

Sign in / Sign up

Export Citation Format

Share Document