WITHDRAWN: PB2425 THE IMPACT OF SPECIMEN VOLUME AND HAEMOLYSIS ON ROUTINE COAGULATION TEST RESULTS: REDUCING THE RECOLLECTION BURDEN IN A HIGH-THROUGHPUT LABORATORY

AbstractBackground:The need to satisfy high-throughput demands for laboratory tests continues to be a challenge. Therefore, we aimed to automate postanalytical phase in hematology and coagulation laboratory by autovalidation of complete blood count (CBC) and routine coagulation test results (prothrombin time [PT], international normalized ratio [PT-INR], activated partial thromboplastin time [APTT], fibrinogen, antithrombin activity [AT] and thrombin time [TT]). Work efficacy and turnaround time (TAT) before and after implementation of automated solutions will be compared.Methods:Ordering panels tailored to specific patient populations were implemented. Rerun and reflex testing rules were set in the respective analyzers’ software (Coulter DxH Connectivity 1601, Beckman Coulter, FL, USA; AutoAssistant, Siemens Healthcare Diagnostics, Germany), and sample status information was transferred into the laboratory information system. To evaluate if the automation improved TAT and efficacy, data from manually verified results in September and October of 2015 were compared with the corresponding period in 2016 when autovalidation was implemented.Results:Autovalidation rates of 63% for CBC and 65% for routine coagulation test results were achieved. At the TAT of 120 min, the percentage of reported results increased substantially for all analyzed tests, being above 90% for CBC, PT, PT-INR and fibrinogen and 89% for APTT. This output was achieved with three laboratory technicians less compared with the period when the postanalytical phase was not automated.Conclusions:Automation allowed optimized laboratory workflow for specific patient populations, thereby ensuring standardized results reporting. Autovalidation of test results proved to be an efficient tool for improvement of laboratory work efficacy and TAT.

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Model estimates of the results of diabetes patients using modern glucometers with tri-color technology for displaying test results

Medical Technologies Assessment and Choice (Медицинские технологии Оценка и выбор) ◽

10.31556/2219-0678.2019.37.3.081-089 ◽

2019 ◽

pp. 81-89

Author(s):

Larisa Dmitrievna Popovich ◽

Svetlana Valentinovna Svetlichnaya ◽

Aleksandr Alekseevich Moiseev

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 1 Diabetes ◽

Economic Benefits ◽

Test Results ◽

Self Monitoring ◽

Patients With Diabetes ◽

The Impact

Diabetes – a disease in which the effect of the treatment substantially depends on the patient. Known a study showed that the use of glucometers with the technology of three-color display of test results facilitates self-monitoring of blood sugar and leads to a decrease in glycated hemoglobin (HbAlc). Purpose of the study: to modeling the impact of using of a glucometer with a color-coded display on the clinical outcomes of diabetes mellitus and calculating, the potential economic benefits of reducing the hospitalization rate of patients with diabetes. Material and methods. Based on data from two studies (O. Schnell et al. and M. Baxter et al.) simulation of the reduction in the number of complications with the use of a glucometer with a color indication. In a study by O. Schnell et al. a decrease of HbA1c by 0.69 percent is shown when using the considered type of glucometers, which was the basis of the model. Results. In the model, the use of a glucometer with a color-coded display for type 1 diabetes led to a decrease in the total number of complications by 9.2 thousand over 5 years per a cohort of 40 thousand patients with different initial levels of HbA1c. In a cohort of 40 thousand patients with type 2 diabetes, the simulated number of prevented complications was 1.7 thousand over 5 years. When extrapolating these data to all patients with diabetes included in the federal register of diabetes mellitus (FRD), the number of prevented complications was 55.4 thousand cases for type 1 diabetes and 67.1 thousand cases for type 2 diabetes. The possible economic effect from the use of the device by all patients with a diagnosis of diabetes, which are included in the FRD, estimated at 1.5 billion rubles for a cohort of patients with type 1 diabetes and 5.3 billion rubles for patients with type 2 diabetes. Conclusion. Improving the effectiveness of self-monitoring, which is the result of the use of glucometers with color indicators, can potentially significantly reduce the incidence of complications in diabetes and thereby provide significant economic benefits to society.

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An improved high-throughput method for assessing the impact of bioformulation on plant parameters: Case study with pigeonpea seeds

Physiological and Molecular Plant Pathology ◽

10.1016/j.pmpp.2021.101657 ◽

2021 ◽

pp. 101657

Author(s):

Sakshi Tewari ◽

Shilpi Sharma

Keyword(s):

High Throughput ◽

High Throughput Method ◽

The Impact

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High Throughput Centrifugal Electrospinning of Polyacrylonitrile Nanofibers for Carbon Fiber Nonwovens

Polymers ◽

10.3390/polym13081313 ◽

2021 ◽

Vol 13 (8) ◽

pp. 1313

Author(s):

Andreas Hoffmann ◽

Alexander J. C. Kuehne

Keyword(s):

High Throughput ◽

Carbon Nanofiber ◽

Fiber Diameter ◽

Carbon Precursor ◽

Production Methods ◽

High Throughput Method ◽

Radial Forces ◽

Fiber Deposition ◽

The Impact ◽

Pan Fibers

Carbon nanofiber nonwovens are promising materials for electrode or filtration applications; however, their utilization is obviated by a lack of high throughput production methods. In this study, we utilize a highly effective high-throughput method for the fabrication of polyacrylonitrile (PAN) nanofibers as a nonwoven on a dedicated substrate. The method employs rotational-, air pressure- and electrostatic forces to produce fibers from the inner edge of a rotating bell towards a flat collector. We investigate the impact of all above-mentioned forces on the fiber diameter, morphology, and bundling of the carbon-precursor PAN fibers. The interplay of radial forces with collector-facing forces has an influence on the uniformity of fiber deposition. Finally, the obtained PAN nanofibers are converted to carbon nonwovens by thermal treatment.

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Do hotel industry operations deteriorate air quality?

Tourism Economics ◽

10.1177/13548166211022423 ◽

2021 ◽

pp. 135481662110224

Author(s):

Liang-Ju Wang ◽

Ming-Hsiang Chen ◽

Zhandong Yang ◽

Ching-Hui (Joan) Su

Keyword(s):

Air Quality ◽

Hotel Industry ◽

Second Step ◽

Test Results ◽

Sales Revenue ◽

Key Indicator ◽

Regression Test ◽

Rolling Regression ◽

The Impact ◽

Regression Tests

This study proposes and tests two hypotheses concerning the effects of hotel industry operations on air quality based on data of 26 major tourist cities in China from 2002 to 2017. The empirical analyses take two steps. In the first step, panel regression test results reveal that hotel industry operations (measured by hotel sales revenue) significantly raise the value of particulate matter (PM)2.5 (the key indicator of air quality), supporting the first hypothesis that hotel industry operations deteriorate air quality and providing empirical evidence of the adverse impact of the hotel industry on air quality. In the second step, subsample analyses support the second hypothesis that the impact of hotel sales revenue on air quality diminishes over time. The results from the rolling regression tests validate the existence of a diminishing effect of hotel industry operations on air quality.

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Viscoelastic Properties of Cell Structures Manufactured Using a Photo-Curable Additive Technology—PJM

Polymers ◽

10.3390/polym13111895 ◽

2021 ◽

Vol 13 (11) ◽

pp. 1895

Author(s):

Tomasz Kozior ◽

Czesław Kundera

Keyword(s):

Viscoelastic Properties ◽

Cellular Structure ◽

Material Selection ◽

Cellular Structures ◽

Test Results ◽

Additive Technology ◽

Polymer Resin ◽

Cell Structures ◽

Relaxation Curves ◽

The Impact

This research paper reviews the test results involving viscoelastic properties of cellular structure models made with the PolyJet Matrix—PJM additive technology. The designed test specimens were of complex cellular structure and made of three various photo-curable polymer resin types. Materials were selected taking into account the so-called “soft” and “tough” material groups. Compressive stress relaxation tests were conducted in accordance with the recommendations of standard ISO 3384, and the impact of the geometric structure shape and material selection on viscoelastic properties, as well as the most favorable geometric variants of the tested cellular structure models were determined. Mathematica and Origin software was used to conduct a statistical analysis of the test results and determine five-parameter functions approximating relaxation curves. The most favorable rheological was adopted and its mean parameters determined, which enables to match both printed model materials and their geometry in the future, to make a component with a specific rheological response. Furthermore, the test results indicated that there was a possibility of modelling cellular structures within the PJM technology, using support material as well.

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Testing for Legionella in Healthcare Facilities: Evaluation of the Reproducibility of Legionella Test Results and the Impact of Time on Viability and Variability

American Journal of Infection Control ◽

10.1016/j.ajic.2013.03.145 ◽

2013 ◽

Vol 41 (6) ◽

pp. S69 ◽

Cited By ~ 1

Author(s):

Sue M. Mietzner ◽

Andrea J. Schaeffer ◽

Sue M. Mietzner ◽

Mohamed H. Yassin ◽

Marilyn M. Wagener ◽

...

Keyword(s):

Test Results ◽

Healthcare Facilities ◽

The Impact

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The drivers of economic growth in China and India: globalization or financial development?

International Journal of Development Issues ◽

10.1108/ijdi-06-2016-0036 ◽

2017 ◽

Vol 16 (1) ◽

pp. 54-84 ◽

Cited By ~ 13

Author(s):

Magda Kandil ◽

Muhammad Shahbaz ◽

Mantu Kumar Mahalik ◽

Duc Khuong Nguyen

Keyword(s):

Economic Growth ◽

Financial Development ◽

Emerging Market ◽

Annual Data ◽

Test Results ◽

Causality Test ◽

Content Type ◽

China And India ◽

Integration Test ◽

The Impact

Purpose Using annual data from 1970 to 2013 for China and India, this paper aims to examine the impact of globalization and financial development on economic growth by endogenizing capital and inflation and drawing comparisons between the two fastest growing emerging market economies. Design/methodology/approach In the long run, co-integration test results indicate that financial development increases economic growth in China and India. Findings The results also reveal that globalization accelerates economic growth in India but, surprisingly, impairs economic growth in China, as it increases competition for exports. The results furthermore disclose that acceleration in capitalization and inflation, as a proxy for aggregate demand, are positively linked to economic growth in China and India. Originality/value Causality test results indicate that both financial development and economic growth are interdependent. In contrast, causality runs from higher economic growth to increased globalization in India, while the results do not support long-term causality between globalization and economic growth in China.

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Implementation of new high-rise building staircase pressure differential system improvements

Building Services Engineering Research and Technology ◽

10.1177/01436244211044669 ◽

2021 ◽

pp. 014362442110446

Author(s):

Dorota Brzezinska ◽

Marcin Fryda

Keyword(s):

Differential System ◽

Technical Note ◽

Pressure Differential ◽

Test Results ◽

High Rise ◽

Lab Experiments ◽

Improvement Method ◽

System Improvement ◽

The Impact ◽

New Buildings

The following technical note demonstrates full-scale staircase test results of the pressure differential system improvement method described by Fryda et al. in 2021. It is a continuation of experimental research on the impact of the escape route’s leakages on the pressure differential systems for staircases. Based on the lab experiments, it has been found that an additional throttle of the leak implemented in the pressure differential system improves its effectiveness and allows it to be more precisely adjusted to the required overpressure. The results presented in this article have confirmed this hypothesis and provided the opportunity to apply for new patent solutions of a special throttle of the leak control and pressure regulating system. The proposed new leakage-based improvements could increase the efficiency of existing systems based on proportional-integral-derivative controller and could also be installed in new buildings.

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