Epidemiology and control of antibiotic resistance in the intensive care unit

2004 ◽  
Vol 17 (4) ◽  
pp. 309-316 ◽  
Author(s):  
Jean Carlet ◽  
Adel Ben Ali ◽  
Annie Chalfine
2020 ◽  
Vol 7 (7) ◽  
pp. 3860-3864
Author(s):  
Kostiv Olga ◽  
Yakymchuk Elena ◽  
Kostiv Sviatoslav ◽  
Dmytriiev Dmytro ◽  
Dmytriiev Kostiantyn

Introduction: This study addresses and evaluates the decrease of antibiotic resistance after introduction of a proposed prevention plan and control complex in the intensive care unit (ICU). Methods: Data from 1,111 bacteriological analyses, taken from patients who received treatment in the ICU of Ternopil University Hospital from January to August 2015 (group 1) and the same period of 2018 (group II), were included in the study. The complex included measures for the prevention of antibiotic resistance spread and for rational antibiotic use. Results: We found that resistance to imipenem changed more than other antibacterial drugs, increased by 60% (р ≤ 0.05), which was conditioned predominantly by Pseudomonas aeruginosa isolates for 100%. A decrease in 39% of polyresistant clinical isolates of Klebsiella pneumoniae in patients of groups I and II showed important prognostic value. Conclusion: A complex of the proposed measures included the division of patients in blocks according to the risk of infectious complications, control of antibiotics administration, adherence to sanitary norms by ICU staff, use of sodium hypochlorite resulting in decrease of pathogenic isolates, and level of antibiotic resistance to specific groups of antibacterial drugs.


2014 ◽  
Vol 44 (5) ◽  
pp. 229-231 ◽  
Author(s):  
S. Alfandari ◽  
J. Gois ◽  
P.-Y. Delannoy ◽  
H. Georges ◽  
N. Boussekey ◽  
...  

Author(s):  
T.F. Stepanova ◽  
L.V. Kataeva ◽  
A.P. Rebeshchenko ◽  
Le Thanh Hai ◽  
Khu Thi Khanh Dung ◽  
...  

The results of studies of resistance to antibiotics microflora isolated from mucous pharynx and rectum of patients intensive care unit newborns of National Hospital of Pediatrics, Hanoi are presented. It is shown that gram-negative bacteria isolated from children have a high resistance to penicillins, cephalosporins and carbapenem. Antibiotic resistance of bacteria isolated from children receiving treatment in «pure» block did not differ from sustainability of the strains, selected from children in «dirty» block.


1991 ◽  
Vol 12 (01) ◽  
pp. 46-54 ◽  
Author(s):  
John M. Boyce

AbstractObjective:To review practices currently used to control transmission of methicillin-resistantStaphylococcusaureus (MRSA) in hospitals, determine the frequency of their use, and discuss the indications for implementing such measures.Design:A questionnaire survey to determine how commonly selected control practices are used, and a literature review of the efficacy of control practices.Participants:Two hundred fifty-six of 360 hospital-based members fo the Society for Hospital Epidemiology of America, Inc. (SHEA) completed the survey questionnaire.Result:Many different combinations of surveillance and control measures are used by hospitals with MRSA. Nine percent of hospitals stated that no special measures were used to control MRSA. The efficacy of commonly used control measures has not been established by controlled trials.Conclusions:Implementing control measures is warranted when MRSA causes a high incidence of serious nosocomial infections, and is desirable when MRSA has been newly introduced into a hospital or into an intensive care unit, or when MRSA accounts for more than 10% of nosocomial staphylococcal isolates. While the value of some practices is well established, measures such as routinely attempting to eradicate carriage of MRSA by colonized patients and personnel require further evaluation.


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