Does Long-Term Post-Bariatric Weight Change Differ Across Antidepressants?

Although meal replacement can lead to weight reduction, there is uncertainty whether this dietary approach implemented into a lifestyle programme can improve long-term dietary intake. In this subanalysis of the Almased Concept against Overweight and Obesity and Related Health Risk (ACOORH) study (n = 463), participants with metabolic risk factors were randomly assigned to either a meal replacement-based lifestyle intervention group (INT) or a lifestyle intervention control group (CON). This subanalysis relies only on data of participants (n = 119) who returned correctly completed dietary records at baseline, and after 12 and 52 weeks. Both groups were not matched for nutrient composition at baseline. These data were further stratified by sex and also associated with weight change. INT showed a higher increase in protein intake related to the daily energy intake after 12 weeks (+6.37% [4.69; 8.04] vs. +2.48% [0.73; 4.23], p < 0.001) of intervention compared to CON. Fat and carbohydrate intake related to the daily energy intake were more strongly reduced in the INT compared to CON (both p < 0.01). After sex stratification, particularly INT-women increased their total protein intake after 12 (INT: +12.7 g vs. CON: −5.1 g, p = 0.021) and 52 weeks (INT: +5.7 g vs. CON: −16.4 g, p = 0.002) compared to CON. Protein intake was negatively associated with weight change (r = −0.421; p < 0.001) after 12 weeks. The results indicate that a protein-rich dietary strategy with a meal replacement can improve long-term nutritional intake, and was associated with weight loss.

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The association of education with long-term weight change in the EPIC-PANACEA cohort

European Journal of Clinical Nutrition ◽

10.1038/ejcn.2012.55 ◽

2012 ◽

Vol 66 (8) ◽

pp. 957-963 ◽

Cited By ~ 12

Author(s):

S Rohrmann ◽

A Steinbrecher ◽

J Linseisen ◽

S Hermann ◽

A May ◽

...

Keyword(s):

Weight Change

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Abstract P290: Short-term Weight Change and Long-term Mortality in the Trials of Hypertension Prevention

Circulation ◽

10.1161/circ.133.suppl_1.p290 ◽

2016 ◽

Vol 133 (suppl_1) ◽

Author(s):

Nancy R Cook ◽

Lawrence J Appel ◽

Paul K Whelton

Keyword(s):

Weight Loss ◽

Weight Change ◽

Phase 1 ◽

Total Mortality ◽

Weight Loss Intervention ◽

Phase 2 ◽

Short Term ◽

Hypertension Prevention ◽

Long Term Mortality

Introduction: Although weight loss has favorable effects on intermediate outcomes, such as blood pressure and insulin resistance, few studies have examined its effects on long-term outcomes including total mortality. Methods: In the Trials of Hypertension Prevention (TOHP) individuals aged 30-54 years with high normal BP were randomized to a weight loss intervention, to one of several other lifestyle or dietary supplement interventions, or to usual care. All participants from Phase 1 (1987-90) and Phase 2 (1990-5) were followed for mortality through 2013. The association of weight change during any of the interventions with long-term mortality up to 18-24 years after the trial periods was examined among 3828 participants who fell into a high baseline weight stratum, defined as body mass index at least 26 kg/m2 in men and 24 kg/m2 in women. Results and Conclusions: There were 1477 high-weight participants in Phase 1 and 2351 in Phase 2, of whom 21% and 50%, respectively, were assigned to a weight loss intervention. Overall, mean weight change during the trial period was -1.8 lbs (-0.8% of baseline body weight) over 1.5 years in Phase 1 and 1.6 lbs (0.8%) over 3-4 years in Phase 2. A total of 556 (15%) lost > 5%, 1,101 (29%) lost <=5%, 1,567 (41%) gained less than 5%, and 604 (16%) gained > 5% in body weight. Corresponding hazard ratios (HRs) for total mortality were 0.82 (95% confidence interval (CI)=0.57-1.18), 0.94 (95% CI=0.72-1.23), 1.00 (reference), and 1.29 (95% CI=0.92-1.80) (p-trend = 0.046). There was a direct linear relationship with percent change in weight during the trial period and later mortality (HR=1.14 per 5% change, 95% CI=1.02-1.28, p=0.019). This association persisted throughout the course of mortality follow-up (Figure). In these healthy individuals taking part in lifestyle and nutrition supplement trials , short-term weight change was directly associated with mortality about two decades later. These results are consistent with a long-term beneficial effect of presumed intentional weight loss on total mortality.

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Effect of long-term olanzapine treatment on weight change in schizophrenia

European Neuropsychopharmacology ◽

10.1016/s0924-977x(00)80346-6 ◽

2000 ◽

Vol 10 ◽

pp. 305 ◽

Cited By ~ 4

Author(s):

J. Gilmore ◽

B.J. Kinon ◽

B.R. Basson ◽

G.D. Tollefson

Keyword(s):

Weight Change ◽

Olanzapine Treatment

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Energy Expenditure, Fat Oxidation, and Body Weight Regulation: A Study of Metabolic Adaptation to Long- Term Weight Change

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem.85.3.6447 ◽

2000 ◽

Vol 85 (3) ◽

pp. 1087-1094 ◽

Cited By ~ 72

Author(s):

Christian Weyer ◽

Richard E. Pratley ◽

Arline D. Salbe ◽

Clifton Bogardus ◽

Eric Ravussin ◽

...

Keyword(s):

Body Weight ◽

Energy Expenditure ◽

Weight Change ◽

Fat Oxidation ◽

Metabolic Adaptation ◽

Weight Regulation ◽

Body Weight Regulation

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Long-Term and Recent Weight Change Are Associated With Reduced Peripheral Bone Density, Deficits in Bone Microarchitecture, and Decreased Bone Strength: The Framingham Osteoporosis Study

Journal of Bone and Mineral Research ◽

10.1002/jbmr.3472 ◽

2018 ◽

Vol 33 (10) ◽

pp. 1851-1858 ◽

Cited By ~ 3

Author(s):

Ching-Ti Liu ◽

Shivani Sahni ◽

Hanfei Xu ◽

Robert R McLean ◽

Kerry E Broe ◽

...

Keyword(s):

Bone Density ◽

Bone Strength ◽

Weight Change ◽

Bone Microarchitecture ◽

Peripheral Bone

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Adherence to the healthy Nordic diet is associated with weight change during 7 years of follow-up

British Journal Of Nutrition ◽

10.1017/s0007114518001344 ◽

2018 ◽

Vol 120 (1) ◽

pp. 101-110 ◽

Cited By ~ 12

Author(s):

Noora Kanerva ◽

Kennet Harald ◽

Satu Männistö ◽

Niina E. Kaartinen ◽

Mirkka Maukonen ◽

...

Keyword(s):

Weight Change ◽

Weight Maintenance ◽

Linear Regression Analysis ◽

Correlation Coefficients ◽

Population Based ◽

Health Examination ◽

Nordic Diet ◽

The Baltic

AbstractStudies indicate that the healthy Nordic diet may improve heart health, but its relation to weight change is less clear. We studied the association between the adherence to the healthy Nordic diet and long-term changes in weight, BMI and waist circumference. Furthermore, the agreement between self-reported and measured body anthropometrics was examined. The population-based DIetary, Lifestyle and Genetic Determinants of Obesity and Metabolic syndrome Study in 2007 included 5024 Finns aged 25–75 years. The follow-up was conducted in 2014 (n 3735). One-third of the participants were invited to a health examination. The rest were sent measuring tape and written instructions along with questionnaires. The Baltic Sea Diet Score (BSDS) was used to measure adherence to the healthy Nordic diet. Association of the baseline BSDS and changes in BSDS during the follow-up with changes in body anthropometrics were examined using linear regression analysis. The agreement between self-reported and nurse-measured anthropometrics was determined with Bland–Altman analysis. Intra-class correlation coefficients between self-reported and nurse-measured anthropometrics exceeded 0·95. The baseline BSDS associated with lower weight (β=−0·056, P=0·043) and BMI (β=−0·021, P=0·031) over the follow-up. This association was especially evident among those who had increased their BSDS. In conclusion, both high initial and improved adherence to the healthy Nordic diet may promote long-term weight maintenance. The self-reported/measured anthropometrics were shown to have high agreement with nurse-measured values which adds the credibility of our results.

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Efficacy of interventions incorporating mobile applications in facilitating weight loss and health behavior change in the Asian population: a systematic review and meta-analysis (Preprint)

10.2196/preprints.28185 ◽

2021 ◽

Author(s):

Siew Min Ang ◽

Juliana Chen ◽

Jolyn Johal ◽

Jia Huan Liew ◽

Yock Young Dan ◽

...

Keyword(s):

Systematic Review ◽

Weight Loss ◽

Health Behavior ◽

Weight Management ◽

Weight Change ◽

Meta Analysis ◽

Asian Population ◽

Health Behavior Change ◽

Controlled Trials

BACKGROUND Smartphone applications (apps) have shown potential in enhancing weight management in the Western population in the short to medium term. With a rapidly growing obesity burden in the Asian populations, researchers are turning to apps as a service delivery platform to reach a greater target audience to efficiently tackle the problem. OBJECTIVE This systematic review and meta-analysis aimed to determine the efficacy of interventions incorporating apps in facilitating weight loss and health behavior change in the Asian population. METHODS Six databases were searched in June 2020. Eligible studies were controlled trials utilizing an app in the intervention in participants aged 18 years or above and from an Asian ethnicity. A meta-analysis to test intervention efficacy, subgroup analyses and post-hoc analyses were conducted to determine the effects of adding app to usual care and study duration. The primary outcome was absolute or percentage weight change while secondary outcomes were changes to lifestyle behaviors. RESULTS A total of 21 studies were included in this review and 17 were selected for the meta-analysis. The pooled effect size across 14 randomized controlled trials for weight change was small to moderate (Hedges’ g = -0.28, 95% CI = -0.44 to -0.12) however, this was not representative of long-term studies (more than a year). Stand-alone app interventions were inefficacious for weight loss but supplementing multi-component usual care with an app led to statistically significant weight change (Hedges’ g = -0.25 95% CI = -0.43 to -0.07). Asian apps were largely culturally adapted and multi-functional, with the most common app features being communication with health professionals and self-monitoring of behaviors and outcomes. CONCLUSIONS More evidence is required to determine the efficacy of apps in the long term and address app non-usage to maximize the potential of the intervention. Future research should determine the efficacy of each component of the multi-component intervention to facilitate study designs that are most effective and cost-efficient for weight management. CLINICALTRIAL PROSPERO REGISTRATION: CRD42020165240.

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Abstract P051: Lifestyle Change In Mid-life And Long-term Weight Gain In Women With And Without History Of Gestational Diabetes Mellitus

Circulation ◽

10.1161/circ.143.suppl_1.p051 ◽

2021 ◽

Vol 143 (Suppl_1) ◽

Author(s):

Jiaxi Yang ◽

Janet Rich-Edwards ◽

Molin Wang ◽

Wafaie W Fawzi ◽

Cuilin Zhang ◽

...

Keyword(s):

Physical Activity ◽

Diabetes Mellitus ◽

Body Weight ◽

Weight Gain ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Weight Change ◽

Lifestyle Change ◽

History Of

Introduction: Identifying strategies to mitigate gradual long-term weight gain is critical for preventing obesity and its related chronic diseases, particularly for persons at high risk, such as women with a history of gestational diabetes mellitus (GDM). We prospectively examined the independent associations between lifestyle changes in mid-life with long-term weight change among women with and without a history of GDM. Hypothesis: We hypothesized that favorable improvements in lifestyle would be associated with less long-term weight gain, particularly among women with a history of GDM. Methods: We used data from the longitudinal Nurses’ Health Study II, with self-reported lifestyle, diet via food frequency questionnaire, and body weight updated every 2-4 years. We analyzed repeated 4-year changes of the following lifestyle factors among parous women after age 40: adherence to a healthy dietary pattern (Alternate Healthy Eating Index score [AHEI]), physical activity (MET-hrs/wk), moderate alcohol intake (servings/d), and non-smoking, in relation to concurrent 4-year change in body weight (lb). We used multivariable generalized estimating equation models to estimate the least-squares mean of 4-year weight change and 95% confidence interval (CI) for each lifestyle change category (e.g., decrease, remain stable, and increase). Results: Our analysis included 61,637 women, of which 3,444 (5.6%) had a history of GDM. Mean of repeated 4-year weight change after age 40 was 3.0 lb (SD=14.3). Improving diet was associated with favorable 4-year weight change, particularly among women with a history of GDM vs. without GDM (AHEI score change from low to high: -6.3 lb [CI: -9.3, -3.4] vs. -2.7 lb [CI: -3.2, -2.2], respectively; p-interaction=0.04). Increasing physical activity was associated with weight maintenance for GDM women only (MET-hrs/wk change from low to high: 0.6 lb [95% CI: -0.6, 1.7] vs. 2.0 lb [95% CI: 1.8, 2.2] for GDM vs. non-GDM, respectively; p-interaction=0.01). Reducing alcohol (decreased servings/d: 1.9 lb [95% CI: 1.2, 2.6] and 2.8 lb [95% CI: 2.6, 2.9] for GDM vs. non-GDM, respectively) and smoking cessation (recent quitter: 9.8 lb [95% CI: 7.1, 12.5] and 8.5 lb [95% CI: 8.0, 9.1] for GDM vs. non-GDM, respectively) were associated with similar patterns in weight change for women with and without prior GDM. Further, the joint association of improving both diet and physical activity from low to high was related to -12.3 lb (95% CI: -19.5, -5.0) and -6.1 lb (95% CI: -8.0, -4.2) of weight loss for GDM vs. non-GDM women, respectively. Conclusions: We observed that attainable improvements in diet quality and physical activity were associated with weight gain prevention. These findings support continued efforts to improve lifestyle as a beneficial strategy to prevent long-term weight gain, particularly among women with a history of GDM.

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