High-normal blood pressure is associated with a cluster of cardiovascular and metabolic risk factors: a population-based study

2009 ◽  
Vol 27 (1) ◽  
pp. 102-108 ◽  
Author(s):  
Simona Bo ◽  
Roberto Gambino ◽  
Luigi Gentile ◽  
Gianfranco Pagano ◽  
Rosalba Rosato ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Population Based ◽  
Metabolic Risk Factors ◽  
Normal Blood ◽  
Metabolic Risk ◽  
Normal Blood Pressure ◽  
Population Based Study

scholarly journals Metabolic Risk Factors of Alzheimer’s Disease, Dementia with Lewy Bodies, and Normal Elderly: A Population-Based Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Chih-Kuang Cheng ◽  
Yu-Chien Tsao ◽  
Yuan-Chih Su ◽  
Fung-Chang Sung ◽  
Hsu-Chih Tai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Ischemic Stroke ◽  
Lower Risk ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Population Based ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Population Based Study

Background. Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) share many risk factors. Evidence suggests that metabolic risk factors are important to AD; however, their association with DLB is unclear. The risk of cardiovascular diseases (CVD) associated with AD and DLB is also uncertain. Thus, this nationwide, population-based study was designed to evaluate the metabolic and CVD risks in AD and DLB. Materials and Methods. Data were obtained from the Taiwan National Health Insurance Research Database. AD patients, DLB patients, and normal control (NC) individuals from 1996 to 2013 were enrolled for risk assessment. Results. In total, 7544 NC individuals, 1324 AD patients, and 562 DLB patients were enrolled. Participants with one or more metabolic risk factors had significantly higher odds of AD or DLB. No significant differences in metabolic risk factors were observed between DLB and AD patients. AD patients had a lower risk of CVD (aHR = 0.67, 95% CI = 0.59–0.76, p value < 0.001) and coronary artery disease (CAD) (aHR = 0.59, 95% CI = 0.51–0.69, p value < 0.001) than NC. DLB patients had a higher risk of ischemic stroke (aHR = 2.27, 95% CI = 1.68–3.06, p value < 0.001) than NC. Conclusion. Metabolic risk factors are important in AD and DLB. Patients with AD might have a lower risk of CAD and ischemic strokes. Patients with DLB might have a higher risk of ischemic stroke.

Migraine is more frequent in individuals with optimal and normal blood pressure: a population-based study

2002 ◽  
Vol 20 (7) ◽  
pp. 1303-1306 ◽  
Author(s):  
Mário Wiehe ◽  
Sandra Costa Fuchs ◽  
Leila B. Moreira ◽  
Renan Stoll Moraes ◽  
Flávio D. Fuchs
Keyword(s):  
Blood Pressure ◽  
Population Based ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Population Based Study

scholarly journals Associations of hair cortisol concentrations with cardio-metabolic risk factors in childhood

2021 ◽  
Author(s):  
Florianne O L Vehmeijer ◽  
Susana Santos ◽  
Yolanda B de Rijke ◽  
Erica L T van den Akker ◽  
Janine F Felix ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Metabolic Diseases ◽  
Standard Deviation Score ◽  
Population Based ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Hair Cortisol ◽  
Reactive Protein ◽  
Biological Stress

Abstract Context Biological stress is related to cardiovascular disease in adults. The associations of stress with cardiovascular and metabolic diseases may originate in childhood. Objective To examine the associations of hair cortisol concentrations at 6 years with cardio-metabolic risk factors at 6 and 10 years. Design, Setting and participants Cortisol concentrations were measured in hair of 6-year-old children (n = 2,598) participating in the Generation R Study, a population-based prospective cohort study in Rotterdam, the Netherlands. Main Outcome Measures Blood pressure, heart rate, concentrations of insulin, glucose, lipids and C-reactive protein in blood at 6 and 10 years. Results Higher hair cortisol concentrations at 6 years were associated with higher systolic blood pressure at 10 years (difference 0.17 standard deviation score (SDS) (95% Confidence Interval (CI) 0.03, 0.31)). The association attenuated into non-significance after adjustment for childhood BMI at 6 years. Higher hair cortisol concentrations at 6 years were associated with an increase in total and LDL cholesterol between 6 and 10 years but not with those measurements at 6 or 10 years. Hair cortisol concentrations were not associated with other cardio-metabolic risk factors at 6 or 10 years. Conclusions Hair cortisol concentrations were not independent of BMI associated with cardio-metabolic risk factors at 6 or 10 years. The associations of biological stress with cardio-metabolic risk factors may develop at later ages.

FGF23, metabolic risk factors, and blood pressure in patients with primary hyperparathyroidism undergoing parathyroid adenomectomy

Surgery ◽  
2016 ◽  
Vol 159 (1) ◽  
pp. 211-217 ◽  
Author(s):  
Inga-Lena Nilsson ◽  
Sophie Norenstedt ◽  
Fredrik Granath ◽  
Jan Zedenius ◽  
Ylva Pernow ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Primary Hyperparathyroidism ◽  
Metabolic Risk Factors ◽  
Metabolic Risk

scholarly journals Maternal nutrition and its intergenerational links to non-communicable disease metabolic risk factors: a systematic review and narrative synthesis

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Elizabeth Wilkins ◽  
Kremlin Wickramasinghe ◽  
Jessie Pullar ◽  
Alessandro R. Demaio ◽  
Nia Roberts ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Dietary Intake ◽  
Maternal Nutrition ◽  
Evidence Base ◽  
Maternal Exposure ◽  
Metabolic Risk Factors ◽  
Adult Offspring ◽  
Metabolic Risk ◽  
Offspring Adiposity

Abstract Background Non-communicable diseases (NCDs) are the leading cause of death and disability globally, while malnutrition presents a major global burden. An increasing body of evidence suggests that poor maternal nutrition is related to the development of NCDs and their risk factors in adult offspring. However, there has been no systematic evaluation of this evidence. Methods We searched eight electronic databases and reference lists for primary research published between 1 January 1996 and 31 May 2016 for studies presenting data on various dimensions of maternal nutritional status (including maternal exposure to famine, maternal gestational weight gain (GWG), maternal weight and/or body mass index (BMI), and maternal dietary intake) during pregnancy or lactation, and measures of at least one of three NCD metabolic risk factors (blood pressure, blood lipids and blood glucose) in the study population of offspring aged 18 years or over. Owing to high heterogeneity across exposures and outcomes, we employed a narrative approach for data synthesis (PROSPERO= CRD42016039244, CRD42016039247). Results Twenty-seven studies from 10 countries with 62,607 participants in total met our inclusion criteria. The review revealed considerable heterogeneity in findings across studies. There was evidence of a link between maternal exposure to famine during pregnancy with adverse blood pressure, blood lipid, and glucose metabolism outcomes in adult offspring in some contexts, with some tentative support for an influence of adult offspring adiposity in this relationship. However, the evidence base for maternal BMI, GWG, and dietary intake of specific nutrients during pregnancy was more limited and revealed no consistent support for a link between these exposures and adult offspring NCD metabolic risk factors. Conclusion The links identified between maternal exposure to famine and offspring NCD risk factors in some contexts, and the tentative support for the role of adult offspring adiposity in influencing this relationship, suggest the need for increased collaboration between maternal nutrition and NCD sectors. However, in view of the current scant evidence base for other aspects of maternal nutrition, and the overall heterogeneity of findings, ongoing monitoring and evaluation using large prospective studies and linked data sets is a major priority.

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