Prevalence of hepatic steatosis as assessed by controlled attenuation parameter (CAP) in subjects with metabolic risk factors in primary care. A population-based study

Background. Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) share many risk factors. Evidence suggests that metabolic risk factors are important to AD; however, their association with DLB is unclear. The risk of cardiovascular diseases (CVD) associated with AD and DLB is also uncertain. Thus, this nationwide, population-based study was designed to evaluate the metabolic and CVD risks in AD and DLB. Materials and Methods. Data were obtained from the Taiwan National Health Insurance Research Database. AD patients, DLB patients, and normal control (NC) individuals from 1996 to 2013 were enrolled for risk assessment. Results. In total, 7544 NC individuals, 1324 AD patients, and 562 DLB patients were enrolled. Participants with one or more metabolic risk factors had significantly higher odds of AD or DLB. No significant differences in metabolic risk factors were observed between DLB and AD patients. AD patients had a lower risk of CVD (aHR = 0.67, 95% CI = 0.59–0.76, p value < 0.001) and coronary artery disease (CAD) (aHR = 0.59, 95% CI = 0.51–0.69, p value < 0.001) than NC. DLB patients had a higher risk of ischemic stroke (aHR = 2.27, 95% CI = 1.68–3.06, p value < 0.001) than NC. Conclusion. Metabolic risk factors are important in AD and DLB. Patients with AD might have a lower risk of CAD and ischemic strokes. Patients with DLB might have a higher risk of ischemic stroke.

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Prevalence of liver steatosis in subjects with risk factors for nonalcoholic fatty liver disease in primary care using controlled attenuation parameter (CAP). A population-based study

Journal of Hepatology ◽

10.1016/s0168-8278(17)31606-9 ◽

2017 ◽

Vol 66 (1) ◽

pp. S590

Author(s):

N. Fabrellas ◽

R. Hernandez ◽

E. Solà ◽

A. Coiduras ◽

P. Ramos ◽

...

Keyword(s):

Risk Factors ◽

Primary Care ◽

Liver Disease ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Liver Steatosis ◽

Population Based ◽

Controlled Attenuation Parameter ◽

Population Based Study ◽

Nonalcoholic Fatty Liver

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Trend of Cardio-Metabolic Risk Factors in Polycystic Ovary Syndrome: A Population-Based Prospective Cohort Study

PLoS ONE ◽

10.1371/journal.pone.0137609 ◽

2015 ◽

Vol 10 (9) ◽

pp. e0137609 ◽

Cited By ~ 24

Author(s):

Fahimeh Ramezani Tehrani ◽

Seyed Ali Montazeri ◽

Farhad Hosseinpanah ◽

Leila Cheraghi ◽

Hadi Erfani ◽

...

Keyword(s):

Risk Factors ◽

Cohort Study ◽

Polycystic Ovary Syndrome ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Polycystic Ovary ◽

Population Based ◽

Metabolic Risk Factors ◽

Metabolic Risk ◽

Ovary Syndrome

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Long-term effects of group exercise on leg muscle strength in female primary care patients with cardio-metabolic risk factors

http://isrctn.com/ ◽

10.1186/isrctn21220201 ◽

2019 ◽

Author(s):

Lillemor A. Nyberg

Keyword(s):

Risk Factors ◽

Primary Care ◽

Muscle Strength ◽

Metabolic Risk Factors ◽

Metabolic Risk ◽

Group Exercise ◽

Long Term Effects ◽

Primary Care Patients ◽

Leg Muscle

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Microalbuminuria and metabolic risk factors in patients with type 2 diabetes in primary care setting in Thailand

Diabetes Research and Clinical Practice ◽

10.1016/j.diabres.2008.12.020 ◽

2009 ◽

Vol 84 (1) ◽

pp. 92-98 ◽

Cited By ~ 9

Author(s):

Wichai Aekplakorn ◽

Supattra Srivanichakorn ◽

Somkiat Sangwatanaroj

Keyword(s):

Risk Factors ◽

Type 2 Diabetes ◽

Primary Care ◽

Care Setting ◽

Primary Care Setting ◽

Metabolic Risk Factors ◽

Metabolic Risk

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Tomato and lycopene consumption is inversely associated with total and cause-specific mortality: a population-based cohort study, on behalf of the International Lipid Expert Panel (ILEP)

British Journal Of Nutrition ◽

10.1017/s0007114519002150 ◽

2019 ◽

Vol 124 (12) ◽

pp. 1303-1310 ◽

Cited By ~ 3

Author(s):

Mohsen Mazidi ◽

Niki Katsiki ◽

Elena S. George ◽

Maciej Banach

Keyword(s):

Risk Factors ◽

Population Based ◽

Metabolic Risk Factors ◽

Favourable Effect ◽

Metabolic Risk ◽

Total Risk ◽

Reactive Protein ◽

Specific Mortality ◽

Cox Proportional Hazard Regression ◽

Long Term Impact

AbstractNo data exist on the associations of dietary tomato and lycopene consumption with total and cause-specific mortality. Using the National Health and Nutrition Examination Surveys 1999–2010, we evaluted the long-term impact of tomato and lycopene intake on total and cause-specific (CHD and cerebrovascular disease) mortality. We also assessed the changes in cardio-metabolic risk factors according to tomato and lycopene intake. Vital status to 31 December 2011 was ascertained. Cox proportional hazard regression models (followed by propensity score matching) were used to investigate the link between tomato and lycopene consumption total, CHD and cerebrovascular mortality. Among the 23 935 participants included (mean age = 47·6 years, 48·8 % men), 3403 deaths occurred during 76·4 months of follow-up. Tomato intake was inversely associated with total (risk ratio (RR) 0·86, 95 % CI 0·81, 0·92), CHD (RR 0·76, 95 % CI 0·70, 0·85) and cerebrovascular (RR 0·70, 95 % CI 0·62, 0·81) mortality. Similar inverse associations were found between lycopene consumption, total (RR 0·76, 95 % CI 0·72, 0·81), CHD (RR 0·73, 95 % CI 0·65, 0·83) and cerebrovascular (RR 0·71, 95 % CI 0·65, 0·78) mortality; these associations were independent of anthropometric, clinical and nutritional parameters. Age and obesity did not affect the association of tomato and lycopene consumption with total, CHD and cerebrovascular mortality. C-reactive protein significantly moderated the link between lycopene and tomato intake with total, CHD and cerebrovascular mortality. ANCOVA showed that participants with a higher tomato and lycopene consumption had a more cardio-protective profile compared with those with a lower intake. Our results highlighted the favourable effect of tomato and lycopene intake on total and cause-specific mortality as well as on cardio-metabolic risk factors. These findings should be taken into consideration for public health strategies.

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