The Impact of Meningococcal Polymerase Chain Reaction Testing on Laboratory Confirmation of Invasive Meningococcal Disease

2012 ◽  
Vol 31 (3) ◽  
pp. 316-318 ◽  
Author(s):  
Richard J. Drew ◽  
Cilian Ó Maoldomhnaigh ◽  
Patrick J. Gavin ◽  
Nicola Oʼ Sullivan ◽  
Karina M. Butler ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Meningococcal Disease ◽  
Invasive Meningococcal Disease ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Laboratory Confirmation ◽  
Polymerase Chain ◽  
The Impact

scholarly journals Culture and Real-time Polymerase Chain reaction sensitivity in the diagnosis of invasive meningococcal disease: Does culture miss less severe cases?

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0212922 ◽  
Author(s):  
Sara Guiducci ◽  
Maria Moriondo ◽  
Francesco Nieddu ◽  
Silvia Ricci ◽  
Elisa De Vitis ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Real Time ◽  
Meningococcal Disease ◽  
Invasive Meningococcal Disease ◽  
Chain Reaction ◽  
Polymerase Chain

scholarly journals Evaluation of non-culture diagnosis of invasive meningococcal disease by polymerase chain reaction (PCR)

2003 ◽  
Vol 39 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Georgina Tzanakaki ◽  
Maria Tsolia ◽  
Vasiliki Vlachou ◽  
Maria Theodoridou ◽  
Anastasia Pangalis ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Meningococcal Disease ◽  
Invasive Meningococcal Disease ◽  
Chain Reaction ◽  
Polymerase Chain

The use of polymerase chain reaction in the diagnosis of invasive meningococcal disease

2015 ◽  
Vol 82 (3) ◽  
pp. 139-143
Author(s):  
C. Fernández-San José ◽  
F.A. Moraga-Llop ◽  
G. Codina ◽  
P. Soler-Palacín ◽  
M. Espiau ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Meningococcal Disease ◽  
Invasive Meningococcal Disease ◽  
Chain Reaction ◽  
Polymerase Chain

Persistent Leptospiruria in Five Dogs Despite Antimicrobial Treatment (2000–2017)

2019 ◽  
Vol 55 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Tara Mauro ◽  
Kenneth Harkin
Keyword(s):  
At Risk ◽  
Polymerase Chain Reaction ◽  
Antimicrobial Treatment ◽  
Renal Tubules ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Pet Owners ◽  
Zoonotic Risk ◽  
The Face ◽  
Polymerase Chain

ABSTRACT In dogs with leptospirosis, doxycycline therapy is recommended as the preferred therapy for its ability to eliminate the organism from all tissues, including the renal tubules. Elimination of organisms from the renal tubules terminates leptospiruria and prevents transmission of the organism. This report describes the discovery of persistent leptospiruria in the face of therapy with doxycycline in four dogs and enrofloxacin in one dog. Leptospiruria was confirmed by polymerase chain reaction testing for pathogenic leptospires in all five dogs. In two dogs, leptospiruria resolved after a change in therapy to enrofloxacin. In three dogs, doxycycline and/or enrofloxacin were ineffective at eliminating leptospiruria, which then resolved after therapy with clarithromycin. Pet owners could be at risk as persistent leptospiruria poses a potential zoonotic risk. The potential reasons for persistent leptospiruria as demonstrated by polymerase chain reaction testing are discussed.

scholarly journals Impact of Multiplex Polymerase Chain Reaction Testing for Respiratory Pathogen Detection in Pediatric Patients

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S503-S503
Author(s):  
Courtney C Sutton ◽  
Patti J Walton ◽  
Montgomery F Williams ◽  
Tracey L Bastian ◽  
Michael Wright ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Multiplex Polymerase Chain Reaction ◽  
Pathogen Detection ◽  
Pediatric Patients ◽  
Respiratory Pathogen ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Polymerase Chain

Leptospirosis: a diagnostic conundrum

2018 ◽  
Vol 48 (4) ◽  
pp. 306-309
Author(s):  
Keerthivasan Gurumurthy ◽  
Harish Belgode Narasimha ◽  
Mukta Wyawahare ◽  
Niranjan Biswal
Keyword(s):  
The Body ◽  
Health Concern ◽  
Andaman Islands ◽  
Public Health Concern ◽  
Chain Reaction ◽  
Pathogenic Leptospira ◽  
Indian States ◽  
Polymerase Chain Reaction Testing ◽  
Laboratory Confirmation ◽  
Polymerase Chain

Leptospirosis is a serious public health concern worldwide. It is highly endemic in the Andaman Islands and its prevalence is increasing in other Indian states. Clinical features are non-specific and diagnosis relies on laboratory confirmation. The gold standard is microscopic agglutination testing, but this is not widely available. Real-time polymerase chain reaction testing of LipL32 antigen provides the earliest detection of pathogenic Leptospira in the body. We found it to be 100% specific, but it should be used in the first 10 days of illness for reliable results.

The Distribution of Enteric Infections Utilizing Stool Microbial Polymerase Chain Reaction Testing in Clinical Practice

2018 ◽  
Vol 63 (7) ◽  
pp. 1900-1909 ◽  
Author(s):  
Jordan E. Axelrad ◽  
Andrew Joelson ◽  
Yael Nobel ◽  
Susan Whittier ◽  
Garrett Lawlor ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Clinical Practice ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Enteric Infections ◽  
Polymerase Chain
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