A comparative study of eugenol and Ocimum sanctum Linn. leaf extract on the antifertility effect in female albino rats

Background: Tulsi (Ocimum sanctum L.) common household plant, a potent adaptogen has been used for its medicinal property for many years. It is known in Ayurveda as Incomparable one, Mother of medicine of Nature and The Queen of Herbs. The present study evaluated the stress induced anti-ulcer effect of tulsi leaves in albino rats.Methods: Albino rats were randomly, allocated to different experimental groups and aqueous leaf extract of Tulsi (Ocimum sanctum) is given for 7 days. Gastric ulcers were induced by cold restrain methods and results were compared with control using distilled water and standard drug Ranitidine.Results: The Anti-ulcer effect of aqueous extract of Tulsi was significant in a dose dependent manner with cold restraint model. The percentage of ulcer protection of Tulsi leaf extract at dose 100mg/kg is 68.85% and at dose of 200mg/kg showed 65.66% and the standard drug Ranitidine showed 78.23% ulcer protection which is significant (p <0.05).Conclusions: The study showed that when Tulsi (Ocimum sanctum) is given at dose 100-200mg/kg for 7 days i.e., pre-treatment in rats for anti-ulcer effect, it caused a significant reduction in the ulcer scores and ulcer index when compared with control group, as evidenced by the gross appearance and histological findings of gastric mucosa in rats. There were few signs of mucosal injury and the percentage of damage was less compared to control group. Serosal surface revealed very few dilated blood vessels and petechial hemorrhages and mucosal surface had few ulcers of varying sizes.

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Effect of Ocimum sanctum Leaf Extract on Entero-Insular Axis by Oral Glucose Tolerance Test in Albino Rats

Pharmacognosy Journal ◽

10.5530/pj.2019.11.177 ◽

2019 ◽

Vol 11 (5) ◽

pp. 1138-1142

Author(s):

Inbaraj Inbaraj SD ◽

Muniappan Muniappan M

Keyword(s):

Glucose Tolerance ◽

Oral Glucose Tolerance Test ◽

Leaf Extract ◽

Glucose Tolerance Test ◽

Tolerance Test ◽

Ocimum Sanctum ◽

Albino Rats ◽

Oral Glucose ◽

Oral Glucose Tolerance

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STUDY ON DEVELOPMENT OF PASTA PRODUCT WITH INCORPORATION OF OCIMUM SANCTUM (BASIL) TO ENHANCE THE SENSORY AND NUTRITIONAL QUALITY

FLORA AND FAUNA ◽

10.33451/florafauna.v24i2pp221-227 ◽

2018 ◽

Vol 24 (2) ◽

Author(s):

PIYUSH MISHRA ◽

DEVENDRA KUMAR BHATT

Keyword(s):

Ambient Temperature ◽

Shelf Life ◽

Nutritional Quality ◽

Leaf Extract ◽

Storage Stability ◽

Natural Antioxidants ◽

Sensory Properties ◽

Ocimum Sanctum ◽

Leaf Powder

Pasta was prepared by incorporation of Ocimum sanctum (Basil) for better textural and sensory properties. The pasta was incorporated with the leaf extract of Ocimum sanctum at different concentrations of control, 5, 10, and 15.The natural antioxidants present in the O. sanctum leaf powder that was incorporated in the fruit leather showed extended shelf-life over three months when compared with control, without any added preservative at ambient temperature. Also the nutritional stability of the product was studied under two flexible packages of polypropylene and polyester out of that the products packed in polypropylene showed better storage stability .

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Appraisal of innovative phytosynthetic CdO NPs from leaf extract of Ocimum Sanctum and their bactericidal activity against different strains

Nanoscale Reports ◽

10.26524/nr.3.9 ◽

2020 ◽

Vol 3 (2) ◽

Author(s):

Aarth R ◽

Sudha A P ◽

Sujatha B ◽

Sowmya Lakshmi K

Keyword(s):

Leaf Extract ◽

Cadmium Oxide ◽

Morphological Properties ◽

Precipitation Method ◽

Ocimum Sanctum ◽

Oxide Nanoparticles ◽

Average Crystalline Size ◽

Face Centered Cubic ◽

Bacterial Strains ◽

X Ray

The phytosynthesis of n-type Cadmium Oxide Nanoparticles reduces the toxicity of the substance and makes it Eco-friendly. This Eco-friendly biosynthesis of CdO NPs was synthesized for the first time from the Queen of herbs, Ocimum Sanctum (holy basil).The biosynthesized Cadmium oxide was prepared using Ocimum leaf extract as a reductant and Cadmium Chloride and hydroxide as cadmium and oxide source materials by Co- Precipitation method. Thus obtained Cadmium Oxide Nanoparticles were characterized by different techniques such as X-ray diffraction (XRD), Fourier Transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM),Energy dispersive X-ray spectroscopy(EDS) to study the structural and morphological properties. XRD pattern exhibited the formation of face centered cubic structure of CdO NPs with an average crystalline size of 11.5nm .The chemical bond formation of CdO NPs were confirmed by FTIR spectrum in the range of (400-4000cm-1). The SEM micrographs revealed the predominant formation of Cauliflower shape with a particle size in the range of 61-142nm. The high purity of the biosynthesized nanoparticles were confirmed by EDS analysis. Further it was tested against gram positive and gram negative bacterial strains and showed significant antibacterial activity. This biosynthetic research study opens an innovative window to progress our understanding of how CdO NPs shows resistance to different bacterial strains.

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