scholarly journals Risk factors associated with disease aggravation among 126 hospitalized patients with COVID-19 in different places in China

Medicine ◽  
2020 ◽  
Vol 99 (45) ◽  
pp. e22971
Author(s):  
Shuai Shao ◽  
Zhiling Zhao ◽  
Feng Wang ◽  
Dandan Chang ◽  
Yong Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hospitalized Patients ◽  
Factors Associated

Risk Factors Associated with Impulsivity Among Hospitalized Patients

2015 ◽  
Vol 30 ◽  
pp. 1856
Author(s):  
R. Masmoudi ◽  
F. Charfeddine ◽  
F. Smaoui ◽  
L. Aribi ◽  
J. Aloulou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hospitalized Patients ◽  
Factors Associated

scholarly journals Molecular epidemiology of Cryptosporidium spp. in North Lebanon

2018 ◽  
Vol 12 (02.1) ◽  
pp. 34S ◽  
Author(s):  
Marwan Osman ◽  
Sadia Benamrouz ◽  
Karine Guyot ◽  
Dima El Safadi ◽  
Hassan Mallat ◽  
...  
Keyword(s):  
Risk Factors ◽  
Molecular Epidemiology ◽  
Gastrointestinal Symptoms ◽  
Control Program ◽  
Hospitalized Patients ◽  
Parasitic Infections ◽  
Cryptosporidium Hominis ◽  
Factors Associated ◽  
Cryptosporidium Spp ◽  
Molecular Tests

Cryptosporidium spp. are enteroparasites with worldwide distribution that infect the gastrointestinal tract of several vertebrates including humans. Human to human, zoonotic, foodborne and waterborne are reported as the main transmission routes of this parasite. Cryptosporidium spp. have been recognized as the predominant cause of waterborne and foodborne outbreaks. However, the epidemiological situation of cryptosporidiosis is not well known in Lebanon, a developing country with a population often affected by intestinal parasitic infections. This study was devoted to determine the prevalence and the genetic diversity of Cryptosporidium spp. in symptomatic hospitalized patients and in two children populations with different socio-economic level in North-Lebanon, as well as the risk factors associated with cryptosporidiosis. Fecal samples obtained from these populations were examined microscopically by modified Ziehl-Neelsen staining as well as nested PCR were done for the detection of Cryptosporidium oocysts. Out of 163 symptomatic hospitalized patients and 249 children, Cryptosporidium was present in 11% and 10.4% respectively according to microscopy examination and/or molecular tests. The genotyping showed the predominance of Cryptosporidium hominis in both populations. Subgenotype analysis of the isolates at the gp60 locus identified three subtypes IdA19, IbA10G2 and IaA18R3 for C. hominis and two subtypes IIaA15G1R1 and IIaA15G2R1 for C. parvum. Moreover, cryptosporidiosis was correlated with having meals outside home and presence of gastrointestinal symptoms especially diarrhea (p <0.05). This work constitutes the first molecular epidemiology study outlining risk factors associated with cryptosporidiosis in Lebanon. These findings support a need of a control program to prevent the circulation of this parasite.

scholarly journals Risk Factors for Recovery of Ampicillin-Sulbactam-Resistant Escherichia coli in Hospitalized Patients

2000 ◽  
Vol 44 (4) ◽  
pp. 1004-1009 ◽  
Author(s):  
Keith S. Kaye ◽  
Anthony D. Harris ◽  
Howard Gold ◽  
Yehuda Carmeli
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Drug Exposure ◽  
Multivariate Analyses ◽  
Statistical Significance ◽  
Hospitalized Patients ◽  
E Coli ◽  
Factors Associated ◽  
Time Period ◽  
Independent Risk Factors

ABSTRACT Ampicillin-sulbactam resistance in Escherichia coli is an emerging problem. This study determined risk factors for the recovery of ampicillin-sulbactam-resistant E. coli in hospitalized patients. A case-control design was used to compare two groups of case patients with control patients. The first group of case patients consisted of patients from whom nosocomially acquired ampicillin-sulbactam-resistant E. coli strains were isolated, and the second group of case patients consisted of patients from whom ampicillin-sulbactam-susceptible E. coli strains were isolated. Control patients were a random selection among 5% of all patients admitted during the same time period. Risk factors analyzed included antimicrobial drug exposure, comorbid conditions, and demographics. Univariate and multivariate analyses were performed. Ampicillin-sulbactam-resistant E. coli strains were isolated from 175 patients, and ampicillin-sulbactam-susceptibleE. coli strains were isolated from 577 patients. Nine hundred thirty-four control patients were selected. Exposure to penicillin antibiotics as a class and to ampicillin and ampicillin-sulbactam individually were the only significant, independent risk factors associated with the isolation of ampicillin-sulbactam-resistant E. coli (odds ratio [OR] = 2.32 [P < 0.001], OR = 3.04 [P = 0.02], and OR = 1.72 [P= 0.04], respectively), but they were not associated with the isolation of ampicillin-sulbactam-susceptible E. coli. Interestingly, exposure to piperacillin-tazobactam tended to protect against the isolation of E. coli strains resistant to ampicillin-sulbactam, but this did not reach statistical significance (OR = 0.13; P = 0.11).

scholarly journals Rate of Antibiotic Use and Associated Risk Factors in COVID-19 Hospitalized Patients

2020 ◽  
Author(s):  
Alysa J. Martin ◽  
Stephanie Shulder ◽  
David Dobrzynski ◽  
Katelyn Quartuccio ◽  
Kelly E. Pillinger
Keyword(s):  
Risk Factors ◽  
Final Analysis ◽  
Antibiotic Use ◽  
Hospital Length ◽  
Hospitalized Patients ◽  
Hospital Length Of Stay ◽  
Antibiotic Prescribing ◽  
Factors Associated ◽  
Secondary Endpoints ◽  
Associated Risk Factors

AbstractBackgroundLiterature suggests that antibiotic prescribing in COVID-19 patients is high, despite low rates of confirmed bacterial infection. There are little data on what drives prescribing habits.ObjectiveThis study sought to determine antibiotic prescribing rates and risk factors for antibiotic prescribing in hospitalized patients. It was the first study to assess risk factors for receiving more than one course of antibiotics.MethodsThis was a retrospective, multi-center, observational study. Patients admitted from March 1, 2020 to May 31, 2020 and treated for PCR-confirmed COVID-19 were included. The primary endpoint was the rate of antibiotic use during hospitalization. Secondary endpoints included risk factors associated with antibiotic use, risk factors associated with receiving more than one antibiotic course, and rate of microbiologically confirmed infections.ResultsA total of 208 encounters (198 patients) were included in the final analysis. Eighty-three percent of patients received at least one course of antibiotics, despite low rates of microbiologically confirmed infection (12%). Almost one-third of patients (30%) received more than one course of antibiotics. Risk factors identified for both antibiotic prescribing and receiving more than one course of antibiotics were more serious illness, increased hospital length of stay, intensive care unit admission, mechanical ventilation, and acute respiratory distress syndrome.Conclusion and relevanceThere were high rates of antibiotic prescribing with low rates of bacterial co-infection. Many patients received more than one course of antibiotics during hospitalization. This study highlights the need for increased antibiotic stewardship practices in COVID-19 patients.

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