scholarly journals Shengmai injection combined with conventional therapy in treating Adriamycin-related cardiotoxicity

Medicine ◽  
2020 ◽  
Vol 99 (45) ◽  
pp. e23084
Author(s):  
Lanchun Liu ◽  
Chao Liu ◽  
Lian Duan ◽  
Jing Bai ◽  
Qiyuan Mao ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Chao-yang Chen ◽  
Ling-yan Lu ◽  
Peng Chen ◽  
Kang-ting Ji ◽  
Jia-feng Lin ◽  
...  

Intradialytic hypotension (IDH) is a global public health problem. A rising number of IDH sufferers resort to Chinese patent medicine, Shengmai Injection (SMI) in China. The objectives of present study are to assess the effectiveness and safety of SMI as an adjunct therapy for IDH. A systematic search of 6 medical databases was performed up to December 2011. Randomized trials involving SMI adjuvant therapy versus conventional therapy were identified. RevMan 5.0 was used for data analysis. Ten randomized clinical trials with 437 participants were identified. Methodological quality was considered inadequate in all trials. Compared with conventional therapy, SMI adjunct therapy showed significant effects in improving the clinic effective rate (P<0.01), decreasing the incidence of IDH episode (P<0.01), decreasing the frequency of nursing interventions (P<0.01), and increasing diastolic blood pressure (P<0.01). There was no statistical significance in the improvement of mean arterial pressure (P=0.22) and systolic blood pressure (P=0.08) between two groups. Four studies had mentioned adverse events, but no serious adverse effects were reported in any of the included trials. In conclusion, SMI adjunct therapy appears to be potentially effective in treatment of IDH and is generally safe. However, further rigorous designed trials are needed.


1969 ◽  
Vol 21 (02) ◽  
pp. 249-258 ◽  
Author(s):  
L. A Sherman ◽  
M. A Goldstein ◽  
H. S Sise

SummaryThree cases have been presented who had a circulating antifactor VIII anticoagulant developing spontaneously in non-hemophilic subjects. Following two short courses of azathioprine in one case there were transient incomplete remissions of a degree not seen in the previous 4 months of observation. In the other two cases complete remissions were observed within three weeks of beginning administration of 6-mercaptopurine. In one of these, a brief relapse was retreated successfully. In 4 other cases not given these drugs and in cases reported in the literature, such a rapid remission was not seen to occur spontaneously and happened only infrequently in cases given corticosteroids. On the basis of this experience, we suggest that in the treatment of antifactor VIII, if the disorder shows no improvement with conventional therapy (blood, factor VIII concentrates, and corticosteroids), a trial with immunosuppressive drugs is warranted.


2015 ◽  
Author(s):  
Paul Lennon ◽  
Sandra Deady ◽  
Marie-Louise Healy ◽  
John Kinsella ◽  
Conrad Timon ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 730-P
Author(s):  
JORDAN E. PINSKER ◽  
SUNIL DESHPANDE ◽  
MEI MEI CHURCH ◽  
MOLLY PIPER ◽  
CAMILLE C. ANDRE ◽  
...  

2020 ◽  
Vol 10 (4) ◽  
pp. 89-92
Author(s):  
Sravani G ◽  
Linga Naik A ◽  
Kranthi A ◽  
Priyanka G

Plant determined medications remains an important source, particularly in creating countries, to look at genuine sicknesses roughly 62-80% of the total populace although everything depends on conventional medication for the therapy of specific disease. Indeed, plants produce a various scope of bioactive atoms creation them an ironic wellspring of an alternate kind of drugs. There are hardly any reports and utilization of plants in conventional mending by either ancestral individuals or indigenous network. Rejuvenating plants are the wellspring of extraordinary monetary estimation of everywhere on over the world. Nature has the best word on us a rich plant riches, and an enormous number of assorted kinds of plants develop in various pieces of the nation. Homegrown medication is as yet a pillar of around 75 to 85% the entire populace and the significant aspect of the conventional therapy the utilization of the plant extricate and the dynamic constituents. Among the 7000 types of rejuvenating plants perceived everywhere on over the world in excess of 9000, valuable medicinal plants are found in India. Unfortunately, just not many of them are utilized for their therapeutic worth. Around 1500 plants systematically utilize the conventional arrangement of Indian medication. Notwithstanding, the ethanopharmacologist, microbiologist, botanist and common item physicist world over today, is continually still looking for therapeutic adequacy of the plants on the phytochemicals. Along these lines, the quest for the new phytochemical is the foremost significant important to research the primer phytochemical examination to Terminalia catappa and Syzygium jumbolanam.


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