Antiemetic Prophylaxis for Postdischarge Nausea and Vomiting and Impact on Functional Quality of Living During Recovery in Patients With High Emetic Risks

Perceived Quality clusters different aspects that influence the customer’s perception of non-functional quality on a product that are perceive through senses. All together those aspects and the harmony between them reflect the producer’s ability to control product parameters and thereby also mirror the functional quality of the product. High Perceived Quality cannot be added to the product at the end of the developing process. Project prerequisites, system solution, factory capability etc. are criterion to succeed. Therefore, it is important to be able to evaluate Perceived Quality early in the process when product system solutions and architecture are defined, although data maturity is low. This paper presents a comprehensive framework to manage and support evaluation of Perceived Quality aspects in a product development process. The framework is based on an industrial process in combination with recent research within the field. The framework focuses on activities that can be performed at different stages in the developing process based on maturity of the CAD or styling data. For example, if the styling data is divided into different components by split-lines it has reached higher level of maturity then styling data that not has been divided. Consequently, the choice of applied method is based on data maturity, regardless phase in the developing process. The framework contains methods based on several different simulation and analysis techniques. Design methods, Computer-Aided Tolerancing and FEA based non-rigid variation simulation are represented in the framework.

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Yoga and Wellness—Key Insights from the Study on General Yoga Programme

NHRD Network Journal ◽

10.1177/2631454120979763 ◽

2021 ◽

Vol 14 (1) ◽

pp. 51-63

Author(s):

Rabindra Acharya ◽

Gopal P. Mahapatra ◽

Kadamibini Acharya

Keyword(s):

Relevant Literature ◽

Health And Wellness ◽

Human Beings ◽

Recent Past ◽

Facilitative Role ◽

Quality Of Living ◽

The Impact ◽

Simplified Form

Human beings have always strived towards excellence and progress since time immemorial. Industrialisation, automation and technological disruptions have led to increased comfort and quality of living of human beings and enhanced output, productivity and efficiency. Consequently, of late, health and wellness are receiving increased attention globally. Stress and stress-related diseases and workplace-related ailments have significantly increased over the last few decades and gained attention from society and industrial organisations. In the recent past, in the coronavirus pandemic context, wellness has been focused upon in many countries, communities and organisations worldwide. Yoga has been part of the Indian ethos for centuries. In this article, the authors discuss the General Yoga Programme (GYP), its broad coverage, and the impact it has had on the participants in terms of their wellness. With the help of a survey of the participants and linking it to relevant literature and research in the field, the authors highlight how GYP is a useful tool for enhancing various wellness dimensions. They recommend that GYP in its simplified form can be extended to the workplace; and also, HR professionals can play a facilitative role in the process.

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Assessing the impact of chemotherapy-induced nausea and vomiting on patients’ quality of life: An Arabic version of the Functional Living Index-Emesis

Journal of Oncology Pharmacy Practice ◽

10.1177/1078155221998447 ◽

2021 ◽

pp. 107815522199844

Author(s):

Abdullah M Alhammad ◽

Nora Alkhudair ◽

Rawan Alzaidi ◽

Latifa S Almosabhi ◽

Mohammad H Aljawadi

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Arabic Language ◽

Nausea And Vomiting ◽

Cancer Center ◽

Arabic Version ◽

Patient Reported ◽

Arabic Speaking ◽

The Impact

Introduction Chemotherapy-induced nausea and vomiting is a serious complication of cancer treatment that compromises patients’ quality of life and treatment adherence, which necessitates regular assessment. Therefore, there is a need to assess patient-reported nausea and vomiting using a validated scale among Arabic speaking cancer patient population. The objective of this study was to translate and validate the Functional Living Index-Emesis (FLIE) instrument in Arabic, a patient-reported outcome measure designed to assess the influence of chemotherapy-induced nausea and vomiting on patients’ quality of life. Methods Linguistic validation of an Arabic-language version was performed. The instrument was administered to cancer patients undergoing chemotherapy in a tertiary hospital's cancer center in Saudi Arabia. Results One-hundred cancer patients who received chemotherapy were enrolled. The participants’ mean age was 53.3 ± 14.9 years, and 50% were female. Half of the participants had a history of nausea and vomiting with previous chemotherapy. The Cronbach coefficient alpha for the FLIE was 0.9606 and 0.9736 for nausea and vomiting domains, respectively, which indicated an excellent reliability for the Arabic FLIE. The mean FLIE score was 110.9 ± 23.5, indicating no or minimal impact on daily life (NIDL). Conclusions The Arabic FLIE is a valid and reliable tool among the Arabic-speaking cancer population. Thus, the Arabic version of the FLIE will be a useful tool to assess the quality of life among Arabic speaking patients receiving chemotherapy. Additionally, the translated instrument will be a useful tool for future research studies to explore new antiemetic treatments among cancer patients.

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The Functional Quality of Soluble Recombinant Polypeptides Produced in Escherichia coli Is Defined by a Wide Conformational Spectrum

Applied and Environmental Microbiology ◽

10.1128/aem.01446-08 ◽

2008 ◽

Vol 74 (23) ◽

pp. 7431-7433 ◽

Cited By ~ 20

Author(s):

Mónica Martínez-Alonso ◽

Nuria González-Montalbán ◽

Elena García-Fruitós ◽

Antonio Villaverde

Keyword(s):

Escherichia Coli ◽

Green Fluorescent Protein ◽

Recombinant Proteins ◽

Fluorescent Protein ◽

Native Structure ◽

Functional Quality ◽

Soluble Aggregates ◽

Recombinant Polypeptides ◽

Green Fluorescent

ABSTRACT We have observed that a soluble recombinant green fluorescent protein produced in Escherichia coli occurs in a wide conformational spectrum. This results in differently fluorescent protein fractions in which morphologically diverse soluble aggregates abound. Therefore, the functional quality of soluble versions of aggregation-prone recombinant proteins is defined statistically rather than by the prevalence of a canonical native structure.

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The impact of postchemotherapy nausea and vomiting on quality of life after moderately emetogenic chemotherapy

Supportive Care in Cancer ◽

10.1007/s005200050182 ◽

1998 ◽

Vol 6 (4) ◽

pp. 389-395 ◽

Cited By ~ 24

Author(s):

J. J. Rusthoven ◽

David Osoba ◽

Charles A. Butts ◽

Louise Yelle ◽

Helen Findlay ◽

...

Keyword(s):

Quality Of Life ◽

Emetogenic Chemotherapy ◽

Nausea And Vomiting ◽

Moderately Emetogenic Chemotherapy ◽

The Impact

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Chemotherapy-induced nausea and vomiting (CINV) with carboplatin plus pemetrexed or carboplatin plus paclitaxel in patients with lung cancer: a propensity score-matched analysis

BMC Cancer ◽

10.1186/s12885-021-07802-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Toshinobu Hayashi ◽

Mototsugu Shimokawa ◽

Koichi Matsuo ◽

Hirotoshi Iihara ◽

Kei Kawada ◽

...

Keyword(s):

Risk Factors ◽

Lung Cancer ◽

Propensity Score ◽

Nausea And Vomiting ◽

Lung Cancer Patients ◽

Pooled Data ◽

Female Sex ◽

Antiemetic Prophylaxis ◽

Delayed Nausea ◽

Independent Risk Factors

Abstract Background Patients with lung cancer who are treated with carboplatin-based chemotherapy regimens often experience chemotherapy-induced nausea and vomiting (CINV). However, knowledge on the effect of regimen and cofactors on the risk of CINV is limited. This study aimed to analyze and compare the incidence of CINV between lung cancer patients undergoing carboplatin plus pemetrexed (CBDCA+PEM) and those undergoing carboplatin plus paclitaxel (CBDCA+PTX) chemotherapy. Methods Pooled data of 240 patients from two prospective observational studies were compared using propensity score matching. Separate multivariate logistic regression analyses were used to identify risk factors for nausea and vomiting following chemotherapy. Results Delayed nausea was significantly more common in patients treated with CBDCA+PEM than in those treated with CBDCA+PTX (51.1% vs. 36.2%, P = 0.04), but the incidence of vomiting did not significantly differ between the two groups (23.4% vs. 14.9%, P = 0.14). The occurrence of CINV peaked on day 4 in the CBDCA+PTX group and on day 5 in the CBDCA+PEM group. Multivariate analysis showed that female sex, younger age, and CBDCA+PEM regimen were independent risk factors for delayed nausea, while female sex was an independent risk factor for delayed vomiting. Conclusions The CBDCA + PEM regimen has a higher risk of causing delayed nausea than the CBDCA + PTX regimen, and aggressive antiemetic prophylaxis should be offered to patients treated with CBDCA + PEM.

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Biostimulation as a Means for Optimizing Fruit Phytochemical Content and Functional Quality of Tomato Landraces of the San Marzano Area

Foods ◽

10.3390/foods10050926 ◽

2021 ◽

Vol 10 (5) ◽

pp. 926

Author(s):

Youssef Rouphael ◽

Giandomenico Corrado ◽

Giuseppe Colla ◽

Stefania De Pascale ◽

Emilia Dell’Aversana ◽

...

Keyword(s):

Fruit Quality ◽

Nutrient Use Efficiency ◽

Mineral Nutrient ◽

Phytochemical Content ◽

Primary And Secondary Metabolites ◽

Tropical Plant ◽

Protected Designation Of Origin ◽

Functional Quality ◽

Nutrient Use

The effect of plant biostimulation on fruits of traditional tomato germplasm is largely unknown. We examined how a tropical plant-derived biostimulant impacts the nutritional, functional, and compositional characteristics of tomato fruits from four landraces, collected in the San Marzano (SM) tomato Protected Designation of Origin (PDO) region, by profiling primary and secondary metabolites. Biostimulation was not able to completely reshuffle the morpho-physiological and nutritional profile of the four landraces. Their distinct phytochemical profile indicated a genotype-specific tuning of the analyzed traits, which also included an improved yield and fruit quality. Biostimulation of SM1 and SM3 increased photosynthetic accumulation of carbohydrate reserves, improved mineral nutrient use efficiency and consequently, yield (+21% and 34%, respectively). Moreover, biostimulation augmented the nutraceutical properties of the SM2 landrace. Interestingly, the plant-derived product increased in all genotypes lycopene, but not polyphenol accumulation in fruits. Our results show the potential of biostimulatory applications towards optimizing the fruit quality of the acclaimed SM landraces, which is suitable to satisfy both the rising consumer demand for premium traditional tomatoes and the technological needs of the food industry.

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THE SIGNIFICANCE OF NATURAL AND SERENE ENVIRONMENT TO IMPROVE THE QUALITY OF LIVING IN TINY HOMES

PLANNING MALAYSIA JOURNAL ◽

10.21837/pm.v19i16.961 ◽

2021 ◽

Vol 19 (16) ◽

Author(s):

Murni Zainal ◽

Azhan Abdul Aziz

Keyword(s):

Case Studies ◽

Urban Area ◽

Well Being ◽

Prototype Model ◽

Quantitative Methodology ◽

Supportive Environment ◽

Detached House ◽

Quality Of Living

Tiny homes are defined as a small dwelling in the form of a moveable unit, cabin or detached house which is sized to meet its occupants’ needs. Besides affordability, sustainability and minimalist lifestyle, the occupants’ demand for a cosy environment with a window or porch overlooking a garden. The objectives of the study are to investigate the benefits of utilising nature and serenity in promoting a supportive environment to achieve user well-being. Quantitative methodology was applied in this study using three case studies (CS1 at Urban area: Prototype Model of Microhouse, CS2 at Sub urban area: The Cabin Boutique Resort and SC3 at Outskirts area: Meraki Tiny House). The tool, ``Perceived Sensory Dimensions “(PSDs)” was used for respondents to evaluate the surrounding environment of the case studies by showing photos of two sensory dimension models (PSDs Nature and Serene). Close-ended questionnaires were distributed to the 21 respondents from the millennials group, to rate each perception for each case study. The results have shown that a natural and serene environment for CS3 is most preferred because of the aspirational quality of its PSDs, followed by CS2 and CS1.

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