Further observations on the pathology of gastric ulcer. (Progress report.)
1910 ◽
Vol 82
(555)
◽
pp. 233-248
◽
Keyword(s):
The gastric ulcers in these experiments were produced by the injection of gastrotoxic serum. In a form er communication (1) it was demonstrated that the serum, formed by immunising the rabbit with the gastric cells of the guinea-pig or with those of another rabbit, on injection into the guinea-pig's peritoneum produced general symptoms of intoxication and patches of necrosis in the mucous membrane of the stomach. In two later communications (2) and (3) the reactions of gastrotoxin in vitro and its precise mode of action in corpore were demonstrated.