The Croonian Lecture. On the irritability of nerves
Its object is principally to investigate the opinion hitherto entertained, that the nerves may be considered as chords that have no power of contraction within themselves, but only serve as a medium by means of which the influence of the brain may be communicated to the muscles, and the impressions made upon the different parts of the body may be conveyed to the brain. After pointing out the extreme difficulty of such an inquiry, owing to the few opportunities that offer for investigating the real state of the nerves in the living body, Mr. Home intimates that he resolved to avail himself of every opportunity that might offer of any operation in surgery performed upon nerves, either in a healthy state, or under the influence of disease, in order to elucidate this intricate point, without neglecting certain experiments he thought he could devise upon animal bodies, before they are wholly deprived of life. The first case, which explains some circumstances respecting the actions of the nerves when under the influence of disease, was that of a middle-aged person, who, having hurt his thumb by a fall, experienced long after an occasional swelling and convulsions in that part, attended with spasms, which at times extended in the direct course of the trunks of the radial nerve up to the head, the patient being at times afflicted with absolute insensibility. In order to put a stop to the progress of tips irritation, which seemed to constitute the disease, it was proposed to divide the nerve as it passes from under the annular ligament of the wrist. This operation was accordingly performed, but not altogether with the desired success, owing probably to the wound not healing by the first intention.