scholarly journals Approach to Multiple Pulmonary Nodules: A Case Report and Review of Literature

2011 ◽  
Vol 11 ◽  
pp. 760-765 ◽  
Author(s):  
Farshid Niknam ◽  
Jiezhong Chen ◽  
Sabar Napaki ◽  
Morteza Aghmesheh
Keyword(s):  
Pulmonary Nodules ◽  
Large Cell Carcinoma ◽  
Large Cell ◽  
Needle Aspiration ◽  
Cytokeratin 20 ◽  
Macrophage Response ◽  
X Ray ◽  
Multiple Pulmonary Nodules ◽  
Diagnosis And Management ◽  
The Right

Chest X-ray and CT examinations often find pulmonary nodules that could be malignant or benign. A case is presented and discussed here in order to improve diagnosis and management of pulmonary nodules. A 62-year-old lady was found to have multiple pulmonary nodules by X-ray when she complained of a cough and fever. This was confirmed by a CT scan. Fine needle aspiration (FNA) of one of the lung lesions reported scant atypical epithelial cells that stained positive for TTF-1 and cytokeratin 7, but negative for cytokeratin 20. Thus, it was suspicious for large cell carcinoma. A videothoracoscopic lung biopsy and histopathology were applied and showed a necrotic nodule with surrounding chronic inflammation and macrophage response, with no evidence of malignant cells. Atypical reactive pneumocytes at the periphery of the lesion (an old infarct) were probably equivalent to the atypical cells seen on cytology. This result changed the diagnosis of our patient from a malignant condition to a benign process. Thus, CT and FNA may give a false positive. A second pathological opinion is very useful for the right diagnosis and management, as shown in our case.

A SWOLLEN MIDDLE FINGER IN A MIDDLE-AGED FARMER

Hand Surgery ◽  
2012 ◽  
Vol 17 (01) ◽  
pp. 121-123 ◽  
Author(s):  
Somprakas Basu ◽  
Shilpi Bhadani ◽  
Vijay Kumar Shukla
Keyword(s):  
Proximal Phalanx ◽  
Middle Finger ◽  
Needle Aspiration ◽  
Excision Biopsy ◽  
Middle Aged ◽  
Cytological Examination ◽  
Diagnostic Dilemma ◽  
X Ray ◽  
The Right ◽  
Bony Erosion

Hand tumors are not common and a swollen finger poses considerable diagnostic dilemma. We present a case of a middle-aged farmer who had presented with a painless swelling of the middle finger of the right hand without any neurovascular deficit or evidence of metastasis. An X-ray of the finger showed cortical expansion and bony erosion of the proximal phalanx. A fine needle aspiration cytological examination was inconclusive. He underwent a digit amputation in view of subsequent morbidity and chances of recurrence following local excision. Biopsy proved it to be a giant cell tumor of the proximal phalanx. Following six months of treatment he is doing well. We herein highlight an unusual tumor of the finger and its diagnostic and treatment challenges.

scholarly journals Pulmonary Hyalinising Granuloma: A report of two cases

2019 ◽  
Vol 19 (2) ◽  
pp. 157
Author(s):  
Ameen Kamona ◽  
Fatma Al Lawati ◽  
Atheel Kamona ◽  
Nasser Al Busaidi ◽  
Yaqoob Al Mahrooqi ◽  
...  
Keyword(s):  
Male Patient ◽  
Pulmonary Nodules ◽  
Definitive Treatment ◽  
X Ray ◽  
Multiple Pulmonary Nodules ◽  
First Case ◽  
Lung Condition ◽  
Chest X Ray ◽  
X Ray Computed

ABSTRACT: Pulmonary hyalinising granuloma (PHG) is a rare fibrosclerosing inflammatory lung condition of unknown aetiology. It is characterised by solitary or multiple pulmonary nodules that are usually found incidentally while imaging the chest for other reasons. We report two cases of histologically proven PHG diagnosed at the Royal Hospital, Muscat, Oman. The first case was a 71-year-old male patient who presented in 2010 with a dry cough, weight loss and bilateral pulmonary nodules. The second case was a 58-year-old male patient who presented in 2012 and was found to have incidental bilateral pulmonary nodules on chest X-ray. Both patients were started on prednisolone and on follow-up the PHG nodules remained stable. Although there is no definitive treatment, PHG generally has an excellent prognosis.Keywords: Granuloma; X-Ray Computed Tomography; Multiple Pulmonary Nodules; Lung; Case Report; Oman.

scholarly journals A Case of Synchronous Triple Primary Lung Cancers Composed of Adenocarcinoma, Squamous Cell Carcinoma and Large Cell Carcinoma in the Right Lung.

Haigan ◽  
1996 ◽  
Vol 36 (2) ◽  
pp. 147-154 ◽  
Author(s):  
Yuichiro Takeda ◽  
Masahiro Seike ◽  
Shigeto Kawachi ◽  
Tatsurou Watanabe ◽  
Shouji Kudoh ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Large Cell Carcinoma ◽  
Large Cell ◽  
Lung Cancers ◽  
The Right

Introduction to Neoplasms of the Lung and Tracheobronchial Tree

Chest Imaging ◽  
2019 ◽  
pp. 253-255
Author(s):  
Melissa L. Rosado-de-Christenson
Keyword(s):  
Lung Cancer ◽  
Cell Carcinoma ◽  
Lung Neoplasm ◽  
Pulmonary Nodules ◽  
Large Cell Carcinoma ◽  
Large Cell ◽  
Cell Types ◽  
Tracheobronchial Tree ◽  
Pulmonary Neoplasms ◽  
Lung Malignancy

The introduction to neoplasms of the lung and tracheobronchial tree addresses the different types of malignant and benign neoplasms of the lung. The most common primary lung neoplasm is lung cancer. It represents the most common cause of cancer mortality in American men and women. Lung cancer is comprised by four major cell types including adenocarcinoma, squamous cell carcinoma, small cell carcinoma and large cell carcinoma. Many patients with lung cancer are symptomatic at presentation and most present with advanced disease. Lung cancer has a variety of imaging manifestations including nodules, masses, post-obstructive atelectasis/pneumonia, intrathoracic lymphadenopathy, extrapulmonary involvement and/or metastatic disease. Carcinoid tumor is an uncommon primary lung malignancy that often affects the airways, but typically exhibits an indolent behavior. Benign pulmonary neoplasms are rare and include neoplasms of the lung and airways such as hamartoma and endobronchial mesenchymal neoplasms. Pulmonary metastases are probably the most common pulmonary neoplasms and usually manifest as multifocal pulmonary nodules and masses.

scholarly journals When a Differential Diagnosis Is Fundamental: Choriocarcinoma Mimicking Lung Carcinoma

2019 ◽  
Vol 8 (11) ◽  
pp. 2018
Author(s):  
Roberto Gasparri ◽  
Giulia Sedda ◽  
Daniela Brambilla ◽  
Lara Girelli ◽  
Cristina Diotti ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Differential Diagnosis ◽  
Lung Carcinoma ◽  
Large Cell Carcinoma ◽  
Large Cell ◽  
Surgical Removal ◽  
Beta Human Chorionic Gonadotropin ◽  
Multiple Metastases ◽  
One Year ◽  
The Right

Background: Choriocarcinoma is a rare malignant disease that is usually associated with a gestational event. Lung metastasis with no evident primary origin and choriocarcinoma, which mimics features of non-small-cell lung cancer, might be misdiagnosed as adenocarcinoma or large-cell carcinoma. This is a pivotal clinical concern since the tumor can lead to various symptoms, seriously affecting the quality of life and can escalate rapidly, with a high mortality rate, compared to lung cancer. Methods: We reported a case of a 37-year-old woman with a history of one-year enhancement of beta-human chorionic gonadotropin levels and only a single nodule in the right upper lobe, with no abnormal findings on the gynecological investigation. Then we retrospectively examined all cases treated in the Division of Thoracic Surgery at the European Institute of Oncology in the last twenty years (from 1998 to 2018). Results: This was the first time in our experience that choriocarcinoma presentation was with a single nodule without a gynecological finding. Moreover, the differential diagnosis between lung carcinoma and choriocarcinoma was achieved only after surgical removal. Conclusions: As confirmed by our literature search, precise and expedited differential diagnosis is essential in choriocarcinoma care (both with single or multiple metastases), to successfully remove the tumor and increase the patient’s chances of survival.

Low temperature x-ray microanalysis of frozen-hydrated tobacco leaves

1984 ◽  
Vol 42 ◽  
pp. 284-285
Author(s):  
S. Edith Taylor ◽  
Patrick Echlin ◽  
May McKoon ◽  
Thomas L. Hayes
Keyword(s):  
Low Temperature ◽  
Lemna Minor ◽  
Root Tips ◽  
Tobacco Leaves ◽  
X Ray ◽  
Whole Cells ◽  
Carbon Coated ◽  
The Right ◽  
Beam Currents ◽  
The University

Low temperature x-ray microanalysis (LTXM) of solid biological materials has been documented for Lemna minor L. root tips. This discussion will be limited to a demonstration of LTXM for measuring relative elemental distributions of P,S,Cl and K species within whole cells of tobacco leaves.Mature Wisconsin-38 tobacco was grown in the greenhouse at the University of California, Berkeley and picked daily from the mid-stalk position (leaf #9). The tissue was excised from the right of the mid rib and rapidly frozen in liquid nitrogen slush. It was then placed into an Amray biochamber and maintained at 103K. Fracture faces of the tissue were prepared and carbon-coated in the biochamber. The prepared sample was transferred from the biochamber to the Amray 1000A SEM equipped with a cold stage to maintain low temperatures at 103K. Analyses were performed using a tungsten source with accelerating voltages of 17.5 to 20 KV and beam currents from 1-2nA.

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