scholarly journals Utah-Stanford Ventilator (Vent4US): Developing a rapidly scalable ventilator for COVID-19 patients with ARDS

Author(s):  
Hongquan Li ◽  
Ethan Li ◽  
Deepak Krishnamurthy ◽  
Patrick Kolbay ◽  
Beca Chacin ◽  
...  

AbstractWe describe a minimum, rapidly scalable ventilator designed for COVID-19 patients with ARDS. Our design philosophy is not only to try to address potential ventilator shortages, but also to account for uncertainties in the supply chains of parts commonly used in traditional ventilators. To do so we employ a modular design approach and broadly explore taking advantage of parts from non-traditional supply chains. In our current prototype, we demonstrate volume control with assist control on a test lung and present a linear actuator-driven pinch valve-based implementation for both pressure control and volume control with decelerating inspiratory flow. We estimate the component cost of the system to be around $500. We publish our draft design documents and current implementation which is open and accessible in the hope that broadening the community globally will accelerate arriving at a solution and that peer review will improve the final design.

2012 ◽  
Vol 203 ◽  
pp. 18-21
Author(s):  
Hui Fang ◽  
Wei Tang ◽  
Yan Jing Meng

The paper analyzes the method of direct tension control, provides repaired method of closed loop speed for tension control of underfeed winder, and designs the systematic hardware figuration and software to effectively meet the demands of different volume control. Furthermore, the problems including pressure control of pressing roller, load distribution control of two-drum winder, tension control of paper, and dynamic compensation control were analyzed and solved through the design of hardware and software of S7-300 PLC.


Author(s):  
Gritt Ahrens ◽  
Oliver Tegel

Abstract Short time to market is a key for success. Information management in product development is one factor for it’s influence. In this paper, the need for a methodology and an IT support for the collection and management of product requirements from identification of customer demands up to the preparation of the final design documents is highlighted. For this, triggers for time consuming iterations are identified and the basic reasons for iterations determined. The lacks of existing approaches in the U.S. and Germany for collecting and handling requirements are discussed, and an integrated concept for requirements management and an appropriate IT support for it are presented.


2019 ◽  
Vol 45 (4) ◽  
pp. 738-760 ◽  
Author(s):  
Susanne Freidberg

Metrics have long served as tools for governing at a distance. In the food industry, major manufacturers have embraced metrics as tools to govern the sustainability of the farms producing their commodity raw materials. This metrical turn has been influenced but also complicated by agricultural datafication, that is, the increasing quantities of data generated on and about farms. Despite the sheer abundance of data that companies might use to measure and drive improvement in on-farm sustainability, they have struggled to collect data suitable for such purposes. Attention to the different kinds of distance and diversity across which metrics are supposed to govern suggests reasons why they may fail to do so, even when wielded by otherwise powerful corporations.


1994 ◽  
Vol 22 (1) ◽  
pp. A89
Author(s):  
Kenneth Davis ◽  
Richard D. Branson ◽  
David T. Porembka

2021 ◽  
Author(s):  
Emre Badur ◽  
Mustafa Altınay ◽  
Pınar Sayın ◽  
Ayşe Surhan Çınar ◽  
leyla türkoğlu ◽  
...  

Abstract Background: To compare the volume-controlled and pressure-controlled ventilation modes with near infrared spectroscopy (NIRS) cerebral oximetry and blood gas status in laparoscopic cholecystectomyMethods: Seventy patients (n=70), who underwent elective laparoscopic cholecystectomy operation were randomized into two groups (volume control ventilation - group V, pressure control ventilation - group P). Demographic data (age, gender, body mass index) and operative data (anesthesia, surgery, and insufflation durations) were recorded. Patients’ single derivation electrocardiogram, pulse oximetry, non-invasive arterial pressure, NIRS cerebral oximetry and end-tidal CO2 parameters were recorded. Measurements were done at the start of anesthesia (T0), at the end of intubation (T1), 5 minutes after the insufflation (T2), at the time just before desufflation (T3) and 5 minutes after desufflation (T4).The patients’ heart rate, systolic and diastolic arterial pressure, saturation of pulse oximetry, and NIRS values were recorded for time points. Additionally, arterial gas results and mechanical ventilation parameters were recorded as well. Results: No significant difference was found in age, sex, body mass index. Operation, anesthesia and insufflation durations were similar for the groups. In Group P, NIRS right T1-2-3 averages and NIRS left T2-3 averages were significantly higher than Group V (p=0.030, p=0.001, p=0.001, p=0.006, p=0.002 respectively). In Group P T1-T2-T4, mean peak pressures and mean plateau pressures were significantly lower than Group V (p=0.003, p=0.001, p<0.001, p=0.011, p=0.001, p<0.001 respectively).Conclusion: Mechanical ventilation that performed in pressure-control ventilation mode is resulted with better tissue oxygenation than volume-control ventilation mode. In pressure-control ventilation mode, peak pressure and plateau pressure were lower.Registration of study at ClinicalTrials.gov was made at 25/01/2021 with the NCT04723043 number.


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