scholarly journals Epidemiological monitoring and control perspectives: application of a parsimonious modelling framework to the COVID-19 dynamics in France

Author(s):  
Mircea T. Sofonea ◽  
Bastien Reyné ◽  
Baptiste Elie ◽  
Ramsès Djidjou-Demasse ◽  
Christian Selinger ◽  
...  

AbstractSARS-Cov-2 virus has spread over the world creating one of the fastest pandemics ever. The absence of immunity, asymptomatic transmission, and the relatively high level of virulence of the COVID-19 infection it causes led to a massive flow of patients in intensive care units (ICU). This unprecedented situation calls for rapid and accurate mathematical models to best inform public health policies. We develop an original parsimonious model that accounts for the effect of the age of infection on the natural history of the disease. Analysing the ongoing COVID-19 in France, we estimate the value of the key epidemiological parameters, such as the basic reproduction number , and the efficiency of the national control strategy. We then use our deterministic model to explore several scenarios posterior to lock-down lifting and compare the efficiency of non pharmaceutical interventions (NPI) described in the literature.

2016 ◽  
Vol 2 (3) ◽  
pp. 145-154
Author(s):  
V V Shmatchenko ◽  
P A Plekhanov

Introduction. The Control System of Maglev Vehicles (further - CSMV) has key value for development maglev. Purpose. In article management by safe movement of maglev vehicles with use of digital radio channel are considered, the international experience is analysed and conclusions for Russian practice are drawn. Methodology. The following methods were used: system approach, analysis and synthesis, generalization. Results. CSMV should consider physical possibilities of magnetic levitation, factors and the restrictions influencing these possibilities, including - the factors connected with safety. CSMV should possess complex of functions allowing effectively, full and safely to realise possibility of magnetic levitation in conditions of specified factors and restrictions. Practical importance. The basic practical results, which can be received by working out CSMV, are: - creation CSMV with high level of control automation and consequently effective and safe; - working out within CSMV typical design decisions, applicable for adaptation to monitoring and control of problems various systems and maglev vehicles; - creation of preconditions of design and perfection of all complex of regulatory framework, conformity which provides safety of maglev infrastructure and vehicles; - reception of interaction experience of the Customer, the research and design organisations, the industry enterprises, the assembly and maintaining organisations at stages of life cycle of CSMV, as key subsystem of maglev. Conclusion. The main appointment of CSMV - creation and constant provide of conditions for safe and effective functioning and development of this new type of transport.


2013 ◽  
Vol 846-847 ◽  
pp. 400-404
Author(s):  
Ya Jing Zhu ◽  
Hui Yu Tian ◽  
Ke Bi

In most of Chinas rural areas, the devices of power distribution area are low configured, simply designed and installed, and have few functions but lots of forms. Beyond, most of them only implement simple functions of power distribution and metering. They couldnt meet the needs of transformation of rural power grid. So its extremely urgent to reconstruct and build intelligent rural power distribution and realize the standardization of information model and the intelligent integrated management of power distribution area to improve the quality and reliability of power supply. In this paper, we analyzed the current development situation of Chinas rural area. Then from the aspect of solving the lagging intelligent level of rural power system, we do some research about developing a new intelligent integrated distribution box and distribution transformer terminal , then we propose the intelligent manage system of power distribution area to realize high intelligent level of power distribution management, high level monitoring and control and greatly improved manage efficiency. At the same time, we enhanced the serving strength for the customer and help to improved the entire intelligent power load , so we could supply high quality power to our customers.


2018 ◽  
Vol 13 (2) ◽  
pp. 21-35
Author(s):  
Hoover Hugo Paredes Mosquera ◽  
Martha Elena Segura Sandoval ◽  
Maria Andrea Orozco Ordoñez ◽  
Hernando Efraín Caicedo Ortiz

 In this article we present a study about the reinforcement of the Peace subject under the Law No. 1732 of 2014 and in the Regulatory Decree No. 1038 of 2015 in Cauca state in the Colombian Republic and legislative which measures that contributes to the strengthening of education considering the post-conflict situation the country is facing. This socio-legal research uses a mixed method. The qualitative approach based on documentary analysis, the ethnography which used the interview as a technique and the quantitative approach which considered the underpinned statistics data which the government entities provided with The study focuses on the pre-school, elementary, middle and high school of the educational institutions in Cauca state by starting a historical compilation of the regulations to determine compliance with legislative guidelines. Notwithstanding, the guidelines of the National Authority of Education for the Peace and subject development in Cauca state the progress results in its enforcement are little and are centered in Popayán as the state capital city without any record of its development on the other remaining 41 towns in the state thus evidencing the absence of an effective monitoring and control of the competent authorities.


Author(s):  
Robert Lukomski ◽  
Kazimierz Wilkosz

A necessary condition for monitoring and control of a Power System (PS) is possessing a credible model of this system. The PS model for a need of dispatchers in national control centre is created in real time. An important element of such a model is a topology model. PS Topology Verification (PSTV) is an important problem in PS engineering. Often this problem is solved together with PS state estimation (Lukomski, & Wilkosz, 2000; Mai, Lefebvre, & Xuan, 2003). Methods, that enable such a solution of the problem, are sophisticated and usually time consuming. They require successful state estimation performance but convergence problems may occur in the case of certain Topology Errors (TEs). Thus, a robust method for PSTV before a state estimation is desired.


Author(s):  
Herman Chu

It is a common practice in electronic packaging to deploy onboard temperature sensing ICs for thermal health monitoring and control. The IT equipment industry has seen exponential increase in power and power density growth on devices and PCBs. In turn, more and more IC temperature sensors are used in highly complex algorithms and are expected to be highly accurate in predicting the local thermal conditions. In many cases they are even used to correlate to air temperature. However, care must be taken in understanding the different factors that influence the temperature readings of these devices. Some of the factors that have direct impact on the quality of the temperature reading include parasitic heating due to adjacent components and placement location, airflow condition, circuit design in connecting these devices to the board, accuracy and tolerance of these devices. In addition, because of the increase in component power density, the temperature difference between the device temperature, for example junction temperature, and board sensor temperature can be very different and the range can vary a lot as well. In this paper, thermal numerical modeling, as well as empirical work at the system and board levels, was performed to understand the implications of the temperature readings from these devices. Several of the commercially available onboard temperature sensing ICs are compared as well. It is the intention of this work to point out these areas in order for thermal and system design practitioners to intelligently use these devices appropriately. Also, a high-level environmental monitoring and control system (EMCS) policy is illustrated for highly configurable multi-board equipment.


2021 ◽  
Vol 5 (3) ◽  
pp. 1-23
Author(s):  
Giuseppe Bombara ◽  
Calin Belta

In this article, we focus on inferring high-level descriptions of a system from its execution traces. Specifically, we consider a classification problem where system behaviors are described using formulae of Signal Temporal Logic (STL). Given a finite set of pairs of system traces and labels, where each label indicates whether the corresponding trace exhibits some system property, we devised a decision-tree-based framework that outputs an STL formula that can distinguish the traces. We also extend this approach to the online learning scenario. In this setting, it is assumed that new signals may arrive over time and the previously inferred formula should be updated to accommodate the new data. The proposed approach presents some advantages over traditional machine learning classifiers. In particular, the produced formulae are interpretable and can be used in other phases of the system’s operation, such as monitoring and control. We present two case studies to illustrate the effectiveness of the proposed algorithms: (1) a fault detection problem in an automotive system and (2) an anomaly detection problem in a maritime environment.


Author(s):  
Luiz Antonio Ugeda Sanches

The present study shows the interdisciplinarity between Geosciences and Law as an inseparable element of the construction of public politics that presuppose the use of geotechnologies. There is a demonstration of how this interdisciplinarity is treated by the law throughout the history of Brazil, as well as its application in the electricity sector, especially in the monitoring and control process of the Agência Nacional de Energia Elétrica (ANEEL).


2013 ◽  
Vol 135 (3) ◽  
Author(s):  
R. Capata ◽  
E. Sciubba

The paper presents a comprehensive review of the gas turbine hybrid vehicle (GTHV) under development at the University of Roma “Sapienza.” A GHTV is an electric vehicle (traction entirely electric on 1 or 2 axles) equipped with a small turbogas operating as a range extender and –when needed- as a recharger for other auxiliaries. After a brief review of the history of the GTHV technology, a few configurations proposed in the past by different Authors are described and critically analyzed. Then, a complete feasibility assessment of a prototype configuration of a GTHV is presented and discussed in detail. Two possible implementations are studied: one for a small city car (peak power 4–8 kW) and one for a sport GT or passenger sedan (50–100 kW). All issues related to the system and component design, packaging, identification of the “optimal” hybridization ratio, performance of the conversion chain (gas turbine + batteries + electrical motor), kinetic energy recovery systems (KERS), mechanical and electric storage devices (flywheels, capacitors, advanced batteries), monitoring and control logic, compliance with the European vehicular ECE emission regulations, are explicitly addressed. One of the most important results of this analysis is though that there are several “nearly optimal” solutions and the final choice for a possible future industrialization would be dictated by manufacturing, commercial or marketing considerations. It because not only the system performance, but also the absolute and relative sizes (i.e., nameplate power) of the turbines and of the battery package depend substantially on the type of driving mission the car is required to perform. In the paper, both theoretical and practical issues are addressed, and on the basis of the analysis of the existing state of the art, it is argued that the GTHV is an environmentally friendly, technically and economically feasible product based on mature components.


Pharmaceutics ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 149
Author(s):  
Michael Choi ◽  
Stuart C. Porter ◽  
Axel Meisen

Oral solid dosage forms that contain APIs in the amorphous state have become commonplace because of many drug substances exhibiting poor water solubility, which negatively impacts their absorption in the human GI tract. While micronization, solvent spray-drying, and hot-melt extrusion can address solubility issues, spray coating of the APIs onto beads and tablets offers another option for producing amorphous drug products. High-level comparisons between bead and tablet coating technologies have the potential for simpler equipment and operation that can reduce the cost of development and manufacturing. However, spray coating directly onto tablets is not without challenges, especially with respect to meeting uniformity acceptance value (AV) criteria, comprising accuracy (mean) and precision (variance) objectives. The feasibility of meeting AV criteria is examined, based on mathematical models for accuracy and precision. The results indicate that the main difficulty in manufacturing satisfactory drug-layered tablets by spray coating is caused by the practical limitations of achieving the necessary coating precision. Despite this limitation, it is shown that AV criteria can be consistently met by appropriate materials monitoring and control as well as processing equipment setup, operation, and maintenance.


Author(s):  
I. M. Davies

SynopsisThe long history of discharge of industrial and domestic waste to the Forth makes the area of particular interest to environmental scientists. The area has been studied both in its own right for the monitoring and control of contamination by trace metals and organohalogen compounds, and in the study of processes which influence the dispersion and effects of these substances. This paper discusses the inputs of contaminants to the area, their occurrence in the water, sediments and biota, and places the Forth in context with other coastal areas of Scotland. The paucity of information concerning organohalogen compounds is contrasted with the extensive work carried out on trace metals.


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