scholarly journals Nutritional status and its associated factors among HIV positive adolescents on Atazanavir-based regimen attending an urban clinic in Uganda

Author(s):  
Dave Darshit ◽  
Ainembabazi Provia ◽  
Nana Nakiddu ◽  
Erin Sodawasser ◽  
Katrina Harper ◽  
...  

AbstractBackgroundAdolescents between the ages of 10-19 represent a growing portion of people living with HIV worldwide. A large proportion of adolescents living with HIV suffer from severe malnutrition because of the chronic ill health and this has been associated with increased morbidity and mortality particularly in Sub-Saharan Africa. Little is known about the nutrition status of adolescents living with HIV who are on second line treatment particularly Atazanavir. Therefore, we assessed the nutrition status and associated factors among HIV positive adolescents on Atazanavir-based regimen attending an urban clinic in Uganda.MethodThis was a cross-sectional study carried out between December 2017 and July 2018. Using convenience sampling, adolescents aged 10-19 years attending an urban clinic in Kampala on Atazanavir-based regimen were enrolled into the study. Nutritional status was assessed using BMI-for-Age and Height-for-age as measures of thinness and stunting respectively. Standard deviation scores (Z scores) were applied to determine the nutritional status. WHO and CDC Z-score cut offs were used to categorize the nutrition status. Data was entered into an electronic database using REDCap. Statistical analysis was done using STATA version 15.1 (Texas, USA).ResultsData from 132 adolescents were included. We found that 28% were malnourished (composite outcome of stunting and thinness). The prevalence malnutrition of thinness was 7.6% with 2.3% being severely thin. The prevalence of stunting was 23.7% with 1.5% being severely stunted. Adolescents with no parent were more likely to be malnourished than adolescents who had either one or both parents (Adjusted Odds Ratio [AOR]: 3.70 95% Confidence Interval [CI]: 1.20-11.37, p=0.023). In addition, adolescents who had attained at least secondary education were less likely to be malnourished (AOR: 0.40, CI:0.17-0.95, P-value=0.037).ConclusionThere is a high proportion of adolescents with HIV who are malnourished. Low level of education (No education and elementary) and having no parent are important risk factors to malnutrition in this population. There is need for optimizing nutrition care for adolescents on HIV treatment.

2009 ◽  
Vol 13 (4) ◽  
pp. 475-479 ◽  
Author(s):  
Elizabeth Nafula Kuria

AbstractObjectiveTo establish the food consumption, dietary habits and nutritional status of people living with HIV/AIDS (PLWHA) and adults whose HIV status is not established.DesignCross-sectional descriptive survey.SettingThika and Bungoma Districts, Kenya.SubjectsA random sample of 439 adults; 174 adults living with HIV/AIDS and 265 adults whose HIV/AIDS status was not established in Thika and Bungoma Districts.ResultsMajority of PLWHA consume foods that are low in nutrients to build up the immune system and help maintain adequate weight, and there is little variety in the foods they consume. More adults who are HIV-positive are undernourished than those whose status is not established. Of the HIV-positive adults, those with a BMI of ≤18·5 kg/m2 were 23·6 % (Thika 20·0 % and Bungoma 25·7 %) while of the adults whose status is not established those with BMI ≤ 18·5 kg/m2 were 13·9 % (Thika 9·3 % and Bungoma 16·7 %).ConclusionsAdults who are HIV-positive are more likely to be undernourished than those whose status is not established, as there is a significant difference (P = 0·000) between the nutritional status (BMI) of PLWHA and those whose HIV/AIDS status is not established. PLWHA consume foods that are low in nutrients to promote their nutritional well-being and health.


2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Patience Adzordor ◽  
Clement Avoka ◽  
Vitalis Bawontuo ◽  
Silas Agbesi ◽  
Desmond Kuupiel

Abstract Background Sub-Saharan Africa (SSA) homes most of the people living with HIV/AIDS in the world. Adolescents/young people are a vulnerable population and at high risk of HIV infection. Identifying and bridging the research gaps on the disclosure of HIV-positive status among adolescents, particularly to their sexual partners, is essential to inform appropriate policy planning and implementation towards preventing HIV transmission. This study will aim to explore literature and describe the evidence on HIV-positive status disclosure among adolescents in SSA. Methods The framework provided by Arksey and O’Malley’s framework and improved by Levac and colleagues will be used to conduct a scoping review. A keyword search for relevant literature presenting evidence on HIV-positive status disclosure among adolescents in SSA will be conducted in CINAHL, PubMed, Science Direct, Google Scholar, and SCOPUS. Date limitations will be removed, but Boolean terms “AND” and “OR” as well as Medical Subject Headings terms will be included where possible and syntax modified to suit the database during the search. Additional relevant articles will be sought from the reference lists of all included studies using a snowballing method. Two reviewers will independently screen the articles at the abstract and full-text screening phases in order to reduce bias and improve the reliability of this study’s findings. A tabular form will be developed using Microsoft Word and piloted for data extraction. Thematic content analysis will be conducted, and a narrative summary of all relevant outcomes reported. Quality appraisal of the included studies for this proposed study will be performed utilizing the recent mixed methods appraisal tool. Discussion The evidence produced by this review may help inform policy and strategies to reduce the incidence of HIV infection among adolescents and improve social support for adolescents living with HIV/AIDS in SSA. It may also reveal literature gaps to guide future researches to further inform HIV policies for adolescents in SSA. Platforms such as peer review journals, policy briefs, and conferences will be used to disseminate this study’s findings.


2019 ◽  
Author(s):  
Adugna Oluma ◽  
Muktar Abadiga ◽  
Getu Mosisa ◽  
Werku Etafa ◽  
Ginenus Fekadu

Abstract Background : Food insecurity and HIV/AIDS are intertwined in a vicious cycle through nutritional, mental health, and behavioral pathways. Food insecurity is a potentially important barrier to the success of antiretroviral treatment, increased hospitalizations, and higher morbidity among HIV-infected individuals in resource-poor settings particularly in sub-Saharan Africa including Ethiopia. Therefore, the purpose of this study was to assess the prevalence of food insecurity and its associated factors among adult people living with HIV/AIDS on follow up receiving ART at public hospitals of wollega zone, west Ethiopia. Methods : An institutional-based cross-sectional study design was conducted on a sample of 428 among people living with HIV/AIDS on follow up receiving anti-retroviral therapy at public hospitals of wollega zones. Data was collected using the Household Food Insecurity Access Scale and dietary diversity scale by interviewer-administered questionnaires. The data was checked, cleaned and entered into Epi data version 3.1 and then exported into Statistical Package for the Social Sciences (SPSS) window version 21 for analysis. Descriptive statistics - cross-tabulation frequency table, mean, standard deviation, percentage, were employed. Bivariate and multiple logistic regression analyses were used with AOR at CI 95% and p<0.05 were used. Result: The overall prevalence of food insecurity among PLWHA receiving ART therapy was 68.8% which was partitioned as mild (23.32%), moderate (29.09%) and severe (16.35%) food in secured. Being single [AOR=3.507(1.377, 8.934)], illiterate [AOR=5.234(1.747, 15.686)], cigarette smoking [AOR=3.577(2.104, 6.081)], presence of anemia (AOR=2.650(1.563, 4.493)] and inadequate dietary diversity [AOR=2.870(1.088, 7.569)] were predictors of food insecurity. Conclusion : The prevalence of food insecurity was relatively high. Educational status, marital status, cigarette smoking, presence of anemia, opportunistic infection and inadequate dietary diversity were the major significant factors affecting food insecurity. We recommended Wollega Zonal Health Bureaus to effectively intervene in behavioral modification and health information dissemination (HID) which is the key strategies to improve food security.


2021 ◽  
Vol 9 (T6) ◽  
pp. 153-158
Author(s):  
Siti Ulfah Rifa'atul Fitri ◽  
Kusman Ibrahim ◽  
Siti Sandra Liani ◽  
Laili Rahayuwati ◽  
Yusshy Kurnia Herliani

Background: Diagnosis and treatment of HIV infection may impact the individual's life, including the physical aspect such as the length of HIV diagnosed, WHO stage, the ART, and the psychological aspect such as the level of stress. People living with HIV/AIDS (PLWHA) have an increased need for energy but they have symptoms of lack of nutrition intake. Therefore, PLWHA has a risk of low nutrition status. The aims of this study were to examine the relationship between nutritional status and health characteristics among HIV/AIDS patients. Methods: A cross-sectional analytical design was conducted among people living with HIV/AIDS (PLWHA) in outpatients’ hospital. A purposive sampling method was used and the sample size was 78 respondents. Data were collected using questionnaire of were the socio-demographic, health characteristic, and nutritional status. The cross-tabulation calculations used chi-square were presented to identify the relationship between nutritional status and health characteristics. Results: The majority of respondents had good health characteristics include the length of HIV diagnosis more than 6 months (79.5%), clinical WHO stage I (61.5%), no stress level (94.9%), and the first choice of ART (83.3%). The nutritional status reported that the majority of the respondents had normal BMI (61.5%), MUAC not at risk (>23,5 cm) (71.8%), and a moderate level of energy intake (37.2%). There were no significant associations between the nutritional status and health characteristics (p > 0.05). Conclusion: The good condition of health characteristics among PLWHA in this study impacted the level the nutritional status.


Author(s):  
Arthureen Tina Nessian ◽  
Leila S. Africa ◽  
Jaidee P. Agne ◽  
Kristine V. Montecillo

Aims: To assess the nutritional and health status, and compliance with treatment and health services of adult people living with HIV/AIDS (PLWHA) attending Liberian Government Hospital (LGH). Study Design:  Cross-sectional study Place and Duration of Study: LGH, Buchanan, Grand Bassa County, 2018 Methodology: The survey was conducted among 90 adults PLWHA. Results: The majority had acute HIV infection, and tuberculosis and herpes zoster were the most contracted opportunistic infections. Although the majority had normal nutritional status, malnutrition was still observed especially among the women. Most had poor diet diversity and claimed to have faced challenges, mainly monetary concerns, while some experienced other traumatic events. A few also showed indications of self-harm. Moreover, they generally have a good health condition and medication adherence and demonstrated substantial knowledge about the disease and its treatment. Compliance was found to be associated with the health status of the participants, but not with their nutrition status, socio-economic and other characteristics. Conclusion: The results provide an insight into the nutritional status and compliance of the adult PLWHA in Liberia. It is hoped that this study would be useful in crafting and enhancing existing intervention programs and policies promoting the better quality of life of adult PLWHA in the country.


2021 ◽  
Author(s):  
Amanuel Demise ◽  
Melake Demena ◽  
Behailu Hawulte ◽  
Abrham Mengistu

Abstract Background Food insecurity has a paramount negative impact on the overall nutritional and health status of people living with the human immune deficiency virus, hence leading to opportunistic infections, rapid disease progression, hospitalizations, poor treatment outcomes, and mortality. Both are intertwined and worsen one another in a vicious cycle through a mixture of nutritional, mental health, and behavioral pathways that heighten vulnerability to, and worsen the severity of, each condition. Nevertheless, little is known about the magnitude of food insecurity and associated factors among adults on antiretroviral therapy in sub-Saharan Africa countries including the current study area. Objectives To assess the magnitude of food insecurity and associated factors among Adults on Antiretroviral Treatment in Dessie referral hospital South Wollo Zone, Northcentral Ethiopia Methods and Materials: An institution-based cross-sectional study was conducted among 420 randomly selected adults living with HIV/AIDS receiving ART in Dessie referral hospital. Data was entered into Epi-data version 3.1 and exported to STATA version 16.0 for cleaning and analysis. Bivariate and multivariate binary logistic regression analysis was carried out to identify factors associated with the outcome variable. Odds ratio along with 95% confidence interval was estimated to measure the strength of the association and the level of statistical significance was declared at a p-value less than 0.05 Results The magnitude of food insecurity among adults on ART was 62.4% (95% CI: 57.6, 66.8]. CD4 count <350 [AOR=3.51, 95% CI: 1.88, 6.52], average monthly household income ≤ 40 USD [AOR= 2.34, 95% CI: 1.42, 3.84], WHO clinical stage III&IV [AOR=2.85, 95% CI: 1.61, 5.04], not getting any support [AOR= 3.04, 95% CI: 1.45, 6.38] were factors significantly associated with food insecurity. Conclusion Around two-thirds of the adult people living with HIV on ART at Dessie referral Hospital were experiencing food insecurity. Thus, social protection interventions targeting patients with CD4 <350, income less than 40 USD/month, WHO clinical stage III &IV, and those patients with no support are crucial interventions for food security.


BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Beauty Mawuenam Nanewortor ◽  
Farrukh Ishaque Saah ◽  
Prince Kubi Appiah ◽  
Hubert Amu ◽  
Kwaku Kissah-Korsah

Abstract Background Nutrition among people living with HIV/AIDS (PLWHA) is essential in their care and management as it has implication for their immune function. We examined the nutritional status and associated factors among HIV positive clients accessing Highly Active Anti-Retroviral Therapy (HAART) at a public hospital in Ghana. Methods This was a descriptive cross-sectional study of 152 clients. Anthropometric measurements for weight and height were carried out in 2019. Data were analysed using SPSS 22.0. Descriptive and analytical statistics comprising frequency, percentage, and binary logistic regression were adopted in presenting the results. Results Seventy-nine percent and 74% of the clients had good nutrition knowledge and attitude, respectively. Also, 42% were malnourished (underweight = 13.8%, and overweight = 28.3%). Clients with primary (AOR = 0.36, 95% CI = 0.07–1.84), JSS/JHS (AOR = 0.26, 95% CI = 0.08–0.84), SSS/SHS (AOR = 0.22, 95% CI = 0.05–1.02) and tertiary (AOR = 0.26, 95% CI = 0.08–0.88) were less likely to be malnourished compared with those with no formal education. Those with good nutrition-related knowledge were 56% (AOR = 0.44, 95% CI = 0.18–1.09) less likely to be malnourished than those with poor knowledge; this was however, not statistically significant. Conclusion We found a high prevalence of malnutrition among the clients which militates against progress towards achieving the Sustainable Development Goal targets 3.3 and 3.4 of stopping AIDS epidemic and preventing premature deaths from malnutrition. Our findings justify the need for the implementation of innovative interventions by stakeholders in Ghana’s health industry to improve the nutritional status of people living with the disease.


2020 ◽  
Author(s):  
Yiqing Xia ◽  
Rachael M. Milwid ◽  
Arnaud Godin ◽  
Mare-Claude Boily ◽  
Leigh F. Johnson ◽  
...  

Background: In many countries in Sub-Saharan Africa, self-reported HIV testing history and awareness of HIV-positive status from household surveys are used to estimate the percentage of people living with HIV (PLHIV) who know their HIV status. Despite widespread use, there is limited empirical information on the sensitivity of those self-reports, which can be affected by non-disclosure. Methods: Bayesian latent class models were used to estimate the sensitivity of self-reported HIV testing history and awareness of HIV-positive status in four Population-based HIV Impact Assessment surveys in Eswatini, Malawi, Tanzania, and Zambia. Antiretroviral (ARV) metabolites biomarkers were used to identify persons on treatment who did not accurately report their status. For those without ARV biomarkers, the pooled estimate of non-disclosure among untreated persons was 1.48 higher than those on treatment. Results: Among PLHIV, the sensitivity of self-reported HIV testing history ranged 96% to 99% across surveys. Sensitivity of self-reported awareness of HIV status varied from 91% to 97%. Non-disclosure was generally higher among men and those aged 15-24 years. Adjustments for imperfect sensitivity did not substantially influence estimates of of PLHIV ever tested (difference <4%) but the proportion of PLHIV aware of their HIV-positive status was higher than the unadjusted proportion (difference <8%). Conclusions: Self-reported HIV testing histories in four Eastern and Southern African countries are generally robust although adjustment for non-disclosure increases estimated awareness of status. These findings can contribute to further refinements in methods for monitoring progress along the HIV testing and treatment cascade.


Author(s):  
Mohamed A. Taha ◽  
Amira Sidig ◽  
Osman. B. M. O. Arbb ◽  
Abbashar M. Hussein ◽  
Musaab M. Alfaki ◽  
...  

At least one-third of the 35.3 million people living with HIV worldwide are infected with latent tuberculosis. Tuberculosis is the most common presenting illness among people living with HIV, including those who are taking antiretroviral treatment. There were an estimated 1.1 million HIV positive new TB cases globally in 2012. Around 75% of these people live in sub-Saharan Africa. Despite its great burden, neurological manifestations have not been described yet in patients with HIV-active tuberculosis, although tuberculosis and HIV have synergistic influence on immunity system which may contribute to change in prevalence or severity of CNS involvement in patients with HIV-active TB co infection. Objectives: To study neurological manifestations in patients with HIV-active tuberculosis.


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