scholarly journals Is Covid-19 seroprevalence different in health care workers as per their risk of exposure? A study from a tertiary care hospital in National Capital Region of India

2021 ◽  
Author(s):  
Sushila Kataria ◽  
Rashmi Phogat ◽  
Pooja Sharma ◽  
Vikas Deswal ◽  
Sazid Alam ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Healthcare Workers ◽  
Tertiary Care ◽  
Health Care Facilities ◽  
Vaccine Hesitancy ◽  
Care Hospital ◽  
Care Workers ◽  
History Of ◽  
Doctors And Nurses

AbstractBackgroundSARS-CoV-2 infection has severely ravaged health systems, economic and social progress globally in 2020. Seroprevalence studies can provide relevant information on the target populations for vaccination. They are relevant not only in the community, but also for critical population subgroups such as nursing homes or health care facilities. They will assist in strategizing the vaccination policy especially since there is limited availability of the vaccine and vaccine hesitancyObjectiveTo evaluate the seroprevalence in Health Care Workers (HCW) at our hospital and to identify parameters which may affect it.MethodologyThe Baseline profiling and seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was assessed among 3258 healthcare workers (HCWs) of Medanta-The Medicity, Gurugram, Haryana, India, as a part of an ongoing cohort study.The fully automated LIAISON® SARS-CoV-2 S1/S2 IgG test using the chemiluminescence immunoassay (CLIA) for the quantitative determination of anti-S1 and anti-S2 specific IgG antibodies to SARS-CoV-2 was used to test serum samples collected before the receipt of the vaccine. Seroprevalence was evaluated as per gender, age, association with previous Covid-19 diagnosis, use of supplements, and role in the hospital and type of exposure.ResultsOf the 3258 participants tested for IgG serology (S1 and S2 proteins) 46.2% (CI 44.4 – 47.9%) were positive (i.e. had an antibody titre more than 15 Au/ml). Higher seroprevalence was seen in the ‘others’ ie non clinical health care workers (including management, research personnel, pharmacists, technicians, general duty staff, housekeeping, security, food and beverage, and facility maintenance teams) (50.2 Au/ml) than that in clinical HCW (ie doctors and nurses)where it was significantly lower (41.4 Au/ml, p= 0.0001). Also, people with history of Covid-19 were found to have significantly higher antibody levels (p = 0.0001). Amongst the healthcare workers, doctors and nurses had higher relative risk of acquiring Covid-19 infection (RR = 1.21; 95% C.I.: 1.12 - 1.31).ConclusionSeroprevalence in healthcare workers at our hospital is high at 46.2%. It is higher in non-clinical HCW than in clinical HCW. The risk of acquiring Covid-19 infection was higher in clinical HCW and thus, this subgroup may benefit most from vaccination. History of Covid-19 may provide double the protection, in particular in those who had it recently.

scholarly journals ASSESSMENT OF NOVEL CORONA VIRUS (COVID-19) AWARENESS AMONG MEDICAL LABORATORY TECHNOLOGIST IN A TERTIARY CARE HOSPITAL IN DELHI: A QUESTIONANAIRE BASED SURVEY

2020 ◽  
pp. 1-5
Author(s):  
Anjali Sharma ◽  
Manju Kumari ◽  
Heena Heena ◽  
Mukul Singh ◽  
Sunil Ranga ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Healthcare Workers ◽  
Tertiary Care ◽  
Medical Laboratory ◽  
Care Hospital ◽  
Online Questionnaire ◽  
Major Health Problem ◽  
Effective Interventions ◽  
Care Workers

Introduction: COVID-19 is rapidly spreading all over the world and is a major health problem in the current scenario. The aim of this study is to assess the awareness of related to COVID-19 disease among the health care workers. Material and methods: This is an online questionnaire based study comprising of 24 questions related to COVID-19 and included 89 health care workers. The responses were analyzed using SPSS software. Results: There were 50 females and 39 males. Among these 35 were trained and 54 were untrained. On analysis we found that females (96.0%) were more aware than males (92.3%). The response of trained persons were more accurate than those of untrained but was not significant (p=0.98). The most aware age group was 51-60 and most aware department was blood bank followed by microbiology. Conclusion: Awareness and preparedness of healthcare workers is low regarding the coronavirus infection. There is need of urgent effective interventions and training programs for various healthcare workers.

scholarly journals Seroprevalence of Antibodies against SARS COV- 2 among Health Care Workers at Tertiary Care Hospital, Uttarakhand: A Retrospective study

2021 ◽  
Author(s):  
Amit K Saini ◽  
Prasan Kumar Panda ◽  
Yogesh Arvind Bahurupi ◽  
Balram Omar ◽  
Akhil T ◽  
...  
Keyword(s):  
Health Care ◽  
Retrospective Study ◽  
Health Care Workers ◽  
Healthcare Workers ◽  
Tertiary Care ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Care Institute ◽  
Care Workers ◽  
Low Prevalence

Abstract Background: The number of confirmed SARS-CoV-2 infections is vastly underestimated. In this context, Seroprevalence surveys are of utmost importance to assess the proportion of the population that has already developed antibodies against the virus and might potentially be protected against subsequent infection. Health care workers face greater risk of developing SARS-CoV-2. Therefore, present retrospective study was undertaken to estimate the prevalence of antibodies against SARS-CoV-2 among healthcare workers at tertiary care institute, Uttarakhand. Material and Methods : Data was gathered from Hospital records of 704 healthcare workers admitted at COVID 19 Unit and attended Covid-OPD of tertiary care institute, Uttarakhand in-between 15th July to 14th Aug 2020. Result: Out of the 704 recruited participants, 14 (1.99%) were seropositive for IgG antibodies against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive RT-PCR) was 4.40%. Conclusion: The present study shows a low prevalence of SARS-CoV-2 IgG antibodies among health care workers. In addition, posting in COVID-19-positive areas was not associated with increased seropositivity. More studies are warranted to assess IgG/IgM antibodies against SARS-CoV-2 among those HCW who are exposed to COVID-19 patients.

scholarly journals Determinants of Tuberculin Reactivity among Health Care Workers: Interpretation of Positivity following BCG Vaccination

1999 ◽  
Vol 10 (2) ◽  
pp. 134-139 ◽  
Author(s):  
Andrew Mckay ◽  
Allen Kraut ◽  
Carol Murdzak ◽  
Annalee Yassi
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Tertiary Care ◽  
Step Test ◽  
Surveillance Program ◽  
Care Hospital ◽  
Cross Sectional Survey ◽  
Bcg Vaccination ◽  
Care Workers ◽  
History Of

OBJECTIVE: To determine the extent to which a history of Bacille Calmette-Guerin (BCG) vaccination influences the likelihood of positive tuberculin skin test (TST) results.DESIGN: Cross-sectional survey using a hospital-based tuberculosis surveillance program.SETTING: Health Sciences Centre, a tertiary care hospital in Winnipeg, Manitoba.METHODS: The 476 health care workers (HCWs) who had TST as part of the surveillance program between 1993 and 1997 constituted the study population. The two-step test was done in 91% of the participants who did not have a positive initial test, defined as 10 mm or greater of induration. Data were gathered through chart review supplemented by a short questionnaire administered to the HCWs.MAIN RESULTS: One hundred and thirty-eight HCWs (29%) had a positive TST. In a stepwise, multiple logistic model controlling for age, sex, job title, work area, age of receiving BCG, time since BCG and duration of employment, only a history of BCG vaccination (odds ratio [OR] 22; 95% CI 12 to 41) and birth outside of Canada (OR 2.6; 95% CI 1.4 to 5.8) were significantly associated with a positive TST. When the definition of a positive TST was modified by increments of 1 mm, from 10 mm up to 20 mm of induration in BCG recipients, BCG was associated with positive reactions with indurations up to 19 mm but not 20 mm or greater. The OR declined with each increment. Of the 84 HCWs who were documented to have at least 20 years between BCG vaccination and testing, 41 (49%) had positive reactions.CONCLUSIONS: BCG vaccination can produce lasting tuberculin reactivity, and indurations of 19 mm or less may be due to the effects of the vaccine.

scholarly journals Psychological status of healthcare workers during COVID-19 pandemic: a single center observational study from Peshawar

2020 ◽  
Vol 6 (4) ◽  
pp. 03-06
Author(s):  
Wajeeha Qayyum ◽  
Asad Khalil ◽  
Mohammad Jawad ◽  
Seema Ashraf
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Psychological Status ◽  
Anxiety And Depression ◽  
Medical Institute ◽  
Care Hospital ◽  
Factors Associated ◽  
Care Workers

Introduction: Infectious pandemics are a significant health risk to the general population, but much more so for the frontline health care workers tending patients at different locations. The increased workload, stress, fear, and anxiety are the burdens to be coped with by health professionals through resort to resiliency and other mechanisms.Objective: To determine the magnitude of depression / anxiety and factors associated with it in health care workers of a tertiary care hospital during the COVID-19 pandemic in Peshawar, Khyber Pakhtunkhwa, Pakistan.Materials & Methods: This cross sectional study was conducted at Rehman Medical Institute, Peshawar after approval from Rehman Medical Institute Research Ethics Committee. A structured questionnaire consisting of two sections was distributed by convenience sampling to health care workers in the hospital, the first part containing demographic information, and the second part consisting of Hospital Anxiety and Depression Scale (HADS) comprised of 14 scales to assess anxiety and depression. Scoring for Normal, Borderline Abnormal, and Definitive Disorder was done as per standard criteria. Data were analyzed for descriptive statistics by SPSS 22. Results: Total 327 participants were included in the study, having mean age of 30.19 ± 7.82 years, of which 230(70.3%) were males. The majority of health care workers 226(69.1%) were suffering from disturbed mental status either in the form of Anxiety (19.9%), Depression (8%) or Mixed Disorder (41.3%). Factors associated with high disease frequency were female gender, age group 21-30 years, nursing staff, workers of ICU and Hostel residence (p value <0.05). Conclusion: COVID-19 related psychological disturbances significantly affected healthcare staff of a tertiary care hospital of Peshawar, being more evident in females, younger age groups, nurses, and ICU staff on duty.

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