scholarly journals The Emergence of SARS-CoV-2 Variant Lambda (C.37) in South America

Author(s):  
Pedro E. Romero ◽  
Alejandra Davila-Barclay ◽  
Guillermo Salvatierra ◽  
Luis Gonzalez ◽  
Diego Cuicapuza ◽  
...  

We report the emergence of a novel lineage of SARS-CoV-2 in South America, termed C.37. It presents a deletion in the ORF1a gene (Δ3675-3677), also found in variants of concern (VOCs) Alpha, Beta, and Gamma, and seven non-synonymous mutations in the Spike gene (Δ247-253, G75V, T76I, L452Q, F490S, T859N). Initially reported in Lima, Peru, in late December 2020, it now accounts for almost 100% of Peruvian genomes in April 2021. It is expanding in Chile and Argentina, and there is evidence of onward transmission in Colombia, Mexico, the USA, Germany, and Israel. On June 15, 2021, the World Health Organization designated C.37 as Variant of Interest (VOI) Lambda.

2021 ◽  
Author(s):  
Priscila Lamb Wink ◽  
Fabiana Caroline Zempulski Volpato ◽  
Francielle Liz Monteiro ◽  
Julia Biz Willig ◽  
Alexandre P. Zavascki ◽  
...  

In June 15, 2021, the lineage Lambda (C.37) of SARS-CoV-2 was considered a variant of interest (VOI) by the World Health Organization. This lineage has high prevalence in some South America countries but it was described only occasionally in Brazil. Here we describe the first report of the SARS-CoV-2 Lambda variant in Southern Brazil. The sequence described in this paper presented all the eight C.37 defining lineage mutations (ORF1a gene: del916;3675-3677; Spike gene: del16;246-252, G75V, T76I, L452Q, F490S, D614G, and T859N) in addition to other 19 mutations. Considering that this VOI has been associated with high rates of transmissibility, the possible spread in the Southern Brazilian community is a matter of concern.


2020 ◽  
pp. 75-83
Author(s):  
Svetlana CEBOTARI ◽  
Victoria BEVZIUC

The activity of the World Health Organization is now becoming a topic in disputes between the big power centres – the USA and China. The role of the WHO is also becoming a research topic not only for researchers in medical sciences, but also for political specialists in international relations. With the COVID-19 crisis, the WHO is becoming a scene of the major challenges – the USA and China. This Article aims to highlight the USA and China relations with reference to the work of the WHO, including the effectiveness of the organization with a global pandemic such as that of the COVID-19.


2017 ◽  
Vol 3 (1) ◽  
pp. 4
Author(s):  
Editorial Office

<p>Cancer is a pressing global health challenge, asserts AMOR’s new Editor-in-Chief (EIC) Dr. Kwong Kwok Wong.“According to the estimation by the World Health Organization, there were 14 million new cases and 8.2 million cancer deaths in 2012,” he tells AMOR Media in an exclusive interview. “By the year 2030, the number of newly-diagnosed cancer cases will increase globally to 22 million and 70% of all cancer deaths will likely occur in low- and medium-income countries in Africa, Asia, and Central and South America,” he adds.</p>


2007 ◽  
Vol 28 (4) ◽  
pp. 154
Author(s):  
John Tapsall

The World Health Organization (WHO) overseeing of antimicrobial resistance (AMR) containment issues in the last decade has varied in intensity. From 1999 onwards, concerted focus from the WHO led to the development of a multi-disciplinary framework for AMR containment at a country level. However, implementation of the WHO Global Strategy for the Containment of Antimicrobial Resistance (the Global Strategy) was overtaken first by events in the USA in 2001 and later by related and other bio-security issues. By 2003, loss of funding and a restructured WHO saw AMR initiatives curtailed. Interest in AMR at the WHO has been recently rekindled and it is hoped that renewed attention will again be focused on this issue by the WHO and its member states.


2009 ◽  
Vol 33 (4) ◽  
pp. 329-338 ◽  
Author(s):  
Gustav Magnus Jarl ◽  
Liselotte Maria Norling Hermansson

There is an increasing need for outcome measures in the orthotic and prosthetic field and specifically a lack of outcome measures in Swedish. The Orthotics and Prosthetics Users' Survey (OPUS) was developed in the USA for assessment of the outcome of orthotic and prosthetic interventions, and could potentially also be used for shoe insoles and orthopaedic shoes. The aims of this study were to translate OPUS into Swedish and test the translated version's linguistic validity in a Swedish context. The Orthotic and Prosthetic Users' Survey was translated into Swedish and back-translated into English, following a modified version of the World Health Organization guidelines. After revision of the Swedish version, 39 Swedish clients (12 men, 27 women) answered the OPUS questionnaires and were systematically debriefed afterwards. Most items were understood correctly by the respondents, but some words and expressions had to be changed to avoid misunderstandings or unintended interpretations. The resulting Swedish version of OPUS, OPUS-Swe, showed acceptable linguistic validity and has potential for use in both clinical practice and scientific settings. Nevertheless, before OPUS-Swe can be fully implemented, its psychometric properties need to be evaluated.


2020 ◽  
Vol 7 (2) ◽  
pp. 42-54
Author(s):  
Flavius Darie ◽  
Illena Tache

This paper’s analysis was triggered by the outbreak of the new virus COVID-19. In December 2019, the Chinese officials alerted the World Health Organization (WHO) of the existence of an unknown deadly virus. Coronavirus has rapidly spread across the world - to Europe, Middle East and the USA, forcing the World Health Organization to declare COVID-19 a global pandemic. Its spread has generated major concerns for the health and economic sectors. Meanwhile, all countries hope for the development of a vaccine. Using as a research method the EGARCH model, this paper investigates if it can be applied to model the trend of volatility of the pharmaceuticals and biotechnology markets, especially during the health crisis. More specifically, this paper tries to identify whether different specifications of univariate GARCH models can usefully anticipate volatility in the stock indices market. The study uses estimates from both a symmetric and an asymmetric GARCH models, namely GARCH (1, 1) and EGARCH models, for the Dow Jones Pharmaceuticals and Biotechnology index (DJUSPN). The dataset is extracted from “Investing.com” and covers the period September 2019 - August 2020, resulting in a total of approximately 252 daily closing prices. The data focuses on the response of the highest capitalized pharmaceutical and biotechnology companies from the US to combat the outbreak of the coronavirus. This study concludes that the EGARCH model is better than the unconditional volatility and the conditional GARCH (1, 1) volatility and it is best suited for modelling and forecasting the fluctuations of the stock indexes.


2020 ◽  
Vol 15 (3) ◽  
pp. 7-12
Author(s):  
Ngoc Cindy Pham ◽  
Yuanqing Li ◽  
Claudio Schapsis ◽  
Tofazzal Hossain ◽  
Huan Henry Pham ◽  
...  

 The Coronavirus Disease 2019 (COVID-19) pandemic emerged in Wuhan, China, spread nationwide and then onto many other countries between December 2019 and early 2020. The implementation of strict quarantine measures in Vietnam has kept a large number of people in isolation and has eventually put the disease under control. Social and physical distancing turned to be an efficient way of slowing the spread of disease and stopping chains of transmission of COVID-19 as well as preventing new ones from appearing (World Health Organization, 2020). Analyzing the World Health Organization (WHO) data, we could see a clear difference in the reported numbers between Vietnam, a developing country, and the USA, one of the leading developed countries in the western hemisphere. We tried to address the question if there are factors that helped local governments to implement helpful rules. We argue that Eastern Asian cultural traits played a role in reducing the spread of COVID-19. We recommend to take this commentary paper, and further research those cultural factors that positively affected the slowdown of the spread of the COVID-19 pandemic in Vietnam.


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