scholarly journals Lexical and acoustic speech features relating to Alzheimer’s disease pathology

Author(s):  
Sunghye Cho ◽  
Katheryn A.Q. Cousins ◽  
Sanjana Shellikeri ◽  
Sharon Ash ◽  
David J. Irwin ◽  
...  

AbstractINTRODUCTIONIn this study, we compared digital speech features of AD and lvPPA patients in a biologically confirmed cohort and related them to specific neuropsychiatric test scores and CSF proteins.METHODSWe extracted language variables with automated lexical and acoustic pipelines from oral picture descriptions of 44 AD and 21 lvPPA patients with autopsy or CSF confirmation of AD pathology. We correlated distinct speech features with MMSE and BNT test scores and CSF p-tau levels.RESULTSLvPPA patients produced fewer verbs, adjectives, and more fillers with lower lexical diversity and higher pause rate than AD. Both groups showed some shared language impairments compared with normal speakers.DISCUSSIONOur speech measures captured differences in speech between the two phenotypes. Also, shared speech markers were linked to the common underlying pathology. This work demonstrates the potential of natural speech analysis in detecting underlying AD pathology.

1973 ◽  
Vol 33 (3) ◽  
pp. 891-900 ◽  
Author(s):  
Itai Zak

The main problem posed in this study is: What are the content and structure of Jewish and American identity? The Jewish-American Identity Scale, which was adapted and refined for this study, was administered in 1971 to four samples, totaling 1006 Jewish-American college students from various parts of the United States. Initially, factor analysis was applied to the separate samples. Intersample comparisons of factor structures indicated a high degree of congruency; consequently, the samples were combined for subsequent analyses. Factor analysis of the test scores demonstrated that most of the common factor variance was appropriated by two relatively orthogonal factors. Items dealing with American identity and those dealing with Jewish identity had medium to high loadings on the two respective factors. These findings supported the hypothesis of the duality and the orthogonality of dimensions of Jewish and American identity, and cast doubt on the notion forwarded by some researchers that Jewish-American identity forms a bipolar continuum.


2020 ◽  
pp. 1-3
Author(s):  
Neha Rehalia ◽  
Vivek Chaudhary

Hypertension is one of the common complications and contributes significantly to perinatal mortality and morbidity. Hypertension is a sign of underlying pathology which may be pre-existing or appear for the first time during pregnancy. The identification of clinical entity and effective management plays a significant role in the outcome of pregnancy, both for the mother and the baby. The main aim of the study was to assess the effect of planned teaching on the knowledge regarding pregnancy induced hypertension among antenatal mothers. The study was conducted on conveniently selected 30 samples of antenatal mothers in Civil hospital, Shahpur. Data was collected by Socio-demographic variables and Self Structured Knowledge Questionnaire. Collected data was analyzed by descriptive and inferential statistics. Results indicated that the planned teaching had significant impact on knowledge regarding pregnancy induced hypertension among antenatal mothers. In this study, posttest knowledge score was associated with education and occupation.


2020 ◽  
Author(s):  
Igor Grossmann ◽  
Nic M. Weststrate ◽  
Michel Ferrari ◽  
Justin Peter Brienza

We have introduced a common wisdom model to establish a shared language, clarify underlying theoretical assumptions, advance assessment tools, and foster evidence-based interventions for stimulating wisdom during challenging societal times. The common wisdom model synthesizes the views of numerous contemporary scientists working on wisdom and includes two components: perspectival meta-cognition and moral aspirations. Having received insightful commentaries on our model, here we consider the overall motivation for the model, address remaining jingle-jangle fallacies, clarify the meaning of morality for wisdom, and expand upon the relationship between moral and meta-cognitive components within the common wisdom model. We reflect on how the common wisdom model provides a nexus for integrating insights across multiple areas of research, affording plentiful opportunities for future research into wisdom’s development, function, and underlying processes. We situate our reflections in the context of present-day pandemic-related uncertainties and unfolding societal shifts.


2017 ◽  
Vol 13 (7S_Part_7) ◽  
pp. P364-P364
Author(s):  
Alexandra Konig ◽  
Frank Rudzicz ◽  
Kathleen C. Fraser ◽  
Liam Kaufman ◽  
Jan Alexandersson ◽  
...  

Author(s):  
Nazia E. Kottasseri ◽  
Mohammed A. Kalathingal ◽  
Shajitha T. Veettil

Atraumatic spontaneous swelling of the Sternoclavicular Joint (SCJ) is not very common in elderly women. The SCJ is an integral part of the shoulder girdle that connects the upper limb to the axial skeleton. Trauma, degeneration, infections and other disease processes that affect synovial joints are the common causes of swelling of the SCJ. Here authors report a case of nontraumatic spontaneous anterior subluxation of the sternoclavicular joint in 66-year-old women without any underlying pathology who presented with sudden onset of a nontender swelling in the suprasternal area. The patient was treated conservatively and remained asymptomatic throughout 6 months follow up.


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