scholarly journals The European Prevention of Alzheimer's Dementia (EPAD) MRI Dataset and Processing Workflow

2021 ◽  
Author(s):  
Luigi Lorenzini ◽  
Silvia Ingala ◽  
Alle Meije Wink ◽  
Joost Kuijer ◽  
Viktor Wottschel ◽  
...  
Keyword(s):  
Image Quality ◽  
Signal To Noise Ratio ◽  
Visual Assessment ◽  
Resting State Fmri ◽  
Poor Quality ◽  
Alzheimer Dementia ◽  
Mri Sequences ◽  
Noise Ratio ◽  
Multi Center Study ◽  
3D Flair

The European Prevention of Alzheimer Dementia (EPAD) is a multi-center study that aims to characterize the preclinical and prodromal stages of Alzheimer's Disease. The EPAD imaging dataset includes core (3D T1w, 3D FLAIR) and advanced (ASL, diffusion MRI, and resting-state fMRI) MRI sequences. Here, we give an overview of the semi-automatic multimodal and multisite pipeline that we developed to curate, preprocess, quality control (QC), and compute image-derived phenotypes (IDPs) from the EPAD MRI dataset. This pipeline harmonizes DICOM data structure across sites and performs standardized MRI preprocessing steps. A semi-automated MRI QC procedure was implemented to visualize and flag MRI images next to site-specific distributions of QC features - i.e. metrics that represent image quality. The value of each of these QC features was evaluated through comparison with visual assessment and step-wise parameter selection based on logistic regression. IDPs were computed from 5 different MRI modalities and their sanity and potential clinical relevance were ascertained by assessing their relationship with biological markers of aging and dementia. The EPAD v1500.0 data release encompassed core structural scans from 1356 participants 842 fMRI, 831 dMRI, and 858 ASL scans. From 1356 3D T1w images, we identified 17 images with poor quality and 61 with moderate quality. Five QC features - Signal to Noise Ratio (SNR), Contrast to Noise Ratio (CNR), Coefficient of Joint Variation (CJV), Foreground-Background energy Ratio (FBER) , and Image Quality Rate (IQR) - were selected as the most informative on image quality by comparison with visual assessment. The multimodal IDPs showed greater impairment in associations with age and dementia biomarkers, demonstrating the potential of the dataset for future clinical analyses.

Image Quality Enhancing by Efficient Histogram Equalization

2014 ◽  
Vol 2 (2) ◽  
pp. 47-58
Author(s):  
Ismail Sh. Baqer
Keyword(s):  
Image Quality ◽  
Contrast Enhancement ◽  
Mean Squared Error ◽  
Signal To Noise Ratio ◽  
Histogram Equalization ◽  
Gray Level ◽  
Signal To Noise ◽  
Squared Error ◽  
Noise Ratio

A two Level Image Quality enhancement is proposed in this paper. In the first level, Dualistic Sub-Image Histogram Equalization DSIHE method decomposes the original image into two sub-images based on median of original images. The second level deals with spikes shaped noise that may appear in the image after processing. We presents three methods of image enhancement GHE, LHE and proposed DSIHE that improve the visual quality of images. A comparative calculations is being carried out on above mentioned techniques to examine objective and subjective image quality parameters e.g. Peak Signal-to-Noise Ratio PSNR values, entropy H and mean squared error MSE to measure the quality of gray scale enhanced images. For handling gray-level images, convenient Histogram Equalization methods e.g. GHE and LHE tend to change the mean brightness of an image to middle level of the gray-level range limiting their appropriateness for contrast enhancement in consumer electronics such as TV monitors. The DSIHE methods seem to overcome this disadvantage as they tend to preserve both, the brightness and contrast enhancement. Experimental results show that the proposed technique gives better results in terms of Discrete Entropy, Signal to Noise ratio and Mean Squared Error values than the Global and Local histogram-based equalization methods

Model-based reconstruction algorithm in the detection of acute trauma-related lesions in brain CT examinations

2021 ◽  
pp. 197140092110087
Author(s):  
Andrea De Vito ◽  
Cesare Maino ◽  
Sophie Lombardi ◽  
Maria Ragusi ◽  
Cammillo Talei Franzesi ◽  
...  
Keyword(s):  
Image Quality ◽  
Iterative Reconstruction ◽  
Signal To Noise Ratio ◽  
Reconstruction Algorithm ◽  
Signal To Noise ◽  
Subjective Image Quality ◽  
Model Based ◽  
Hybrid Iterative Reconstruction ◽  
Noise Ratio ◽  
Enhanced Computed Tomography

Background and purpose To evaluate the added value of a model-based reconstruction algorithm in the assessment of acute traumatic brain lesions in emergency non-enhanced computed tomography, in comparison with a standard hybrid iterative reconstruction approach. Materials and methods We retrospectively evaluated a total of 350 patients who underwent a 256-row non-enhanced computed tomography scan at the emergency department for brain trauma. Images were reconstructed both with hybrid and model-based iterative algorithm. Two radiologists, blinded to clinical data, recorded the presence, nature, number, and location of acute findings. Subjective image quality was performed using a 4-point scale. Objective image quality was determined by computing the signal-to-noise ratio and contrast-to-noise ratio. The agreement between the two readers was evaluated using k-statistics. Results A subjective image quality analysis using model-based iterative reconstruction gave a higher detection rate of acute trauma-related lesions in comparison to hybrid iterative reconstruction (extradural haematomas 116 vs. 68, subdural haemorrhages 162 vs. 98, subarachnoid haemorrhages 118 vs. 78, parenchymal haemorrhages 94 vs. 64, contusive lesions 36 vs. 28, diffuse axonal injuries 75 vs. 31; all P<0.001). Inter-observer agreement was moderate to excellent in evaluating all injuries (extradural haematomas k=0.79, subdural haemorrhages k=0.82, subarachnoid haemorrhages k=0.91, parenchymal haemorrhages k=0.98, contusive lesions k=0.88, diffuse axonal injuries k=0.70). Quantitatively, the mean standard deviation of the thalamus on model-based iterative reconstruction images was lower in comparison to hybrid iterative one (2.12 ± 0.92 vsa 3.52 ± 1.10; P=0.030) while the contrast-to-noise ratio and signal-to-noise ratio were significantly higher (contrast-to-noise ratio 3.06 ± 0.55 vs. 1.55 ± 0.68, signal-to-noise ratio 14.51 ± 1.78 vs. 8.62 ± 1.88; P<0.0001). Median subjective image quality values for model-based iterative reconstruction were significantly higher ( P=0.003). Conclusion Model-based iterative reconstruction, offering a higher image quality at a thinner slice, allowed the identification of a higher number of acute traumatic lesions than hybrid iterative reconstruction, with a significant reduction of noise.

Minimizing table time in patients with claustrophobia using focused ferumoxytol-enhanced MR angiography (f-FEMRA): a feasibility study

2021 ◽  
Vol 94 (1125) ◽  
pp. 20210430
Author(s):  
Puja Shahrouki ◽  
Kim-Lien Nguyen ◽  
John M. Moriarty ◽  
Adam N. Plotnik ◽  
Takegawa Yoshida ◽  
...  
Keyword(s):  
Image Quality ◽  
Mr Angiography ◽  
Signal To Noise Ratio ◽  
Diagnostic Image Quality ◽  
Diagnostic Confidence ◽  
Motion Artefact ◽  
Scan Time ◽  
Wilcoxon Rank Sum Test ◽  
Significant Difference ◽  
Noise Ratio

Objectives: To assess the feasibility of a rapid, focused ferumoxytol-enhanced MR angiography (f-FEMRA) protocol in patients with claustrophobia. Methods: In this retrospective study, 13 patients with claustrophobia expressed reluctance to undergo conventional MR angiography, but agreed to a trial of up to 10 min in the scanner bore and underwent f-FEMRA. Thirteen matched control patients who underwent gadolinium-enhanced MR angiography (GEMRA) were identified for comparison of diagnostic image quality. For f-FEMRA, the time from localizer image acquisition to completion of the angiographic acquisition was measured. Two radiologists independently scored images on both f-FEMRA and GEMRA for arterial and venous image quality, motion artefact and diagnostic confidence using a 5-point scale, five being best. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in the aorta and IVC were measured. The Wilcoxon rank-sum test, one-way ANOVA with Tukey correction and two-tailed t tests were utilized for statistical analyses. Results: All scans were diagnostic and assessed with high confidence (scores ≥ 4). Average scan time for f-FEMRA was 6.27 min (range 3.56 to 10.12 min), with no significant difference between f-FEMRA and GEMRA in diagnostic confidence (4.86 ± 0.24 vs 4.69 ± 0.25, p = 0.13), arterial image quality (4.62 ± 0.57 vs 4.65 ± 0.49, p = 0.78) and motion artefact score (4.58 ± 0.49 vs 4.58 ± 0.28, p > 0.99). f-FEMRA scored significantly better for venous image quality than GEMRA (4.62 ± 0.42 vs 4.19 ± 0.56, p = 0.04). CNR in the IVC was significantly higher for steady-state f-FEMRA than GEMRA regardless of the enhancement phase (p < 0.05). Conclusions: Comprehensive vascular MR imaging of the thorax, abdomen and pelvis can be completed in as little as 5 min within the magnet bore using f-FEMRA, facilitating acceptance by patients with claustrophobia and streamlining workflow. Advances in knowledge: A focused approach to vascular imaging with ferumoxytol can be performed in patients with claustrophobia, limiting time in the magnet bore to 10 min or less, while acquiring fully diagnostic images of the thorax, abdomen and pelvis.

Retinal Digital Image Quality Improvement as A Diabetes Retinopatic Disease Detection Effort

2020 ◽  
Vol 4 (2) ◽  
pp. 53-60
Author(s):  
Latifah Listyalina ◽  
Yudianingsih Yudianingsih ◽  
Dhimas Arief Dharmawan
Keyword(s):  
Image Processing ◽  
Diabetic Retinopathy ◽  
Image Quality ◽  
Digital Image ◽  
Signal To Noise Ratio ◽  
Histogram Equalization ◽  
Vital Role ◽  
Retinal Images ◽  
Signal To Noise ◽  
Noise Ratio

Image processing is a technical term useful for modifying images in various ways. In medicine, image processing has a vital role. One example of images in the medical world, namely retinal images, can be obtained from a fundus camera. The retina image is useful in the detection of diabetic retinopathy. In general, direct observation of diabetic retinopathy is conducted by a doctor on the retinal image. The weakness of this method is the slow handling of the disease. For this reason, a computer system is required to help doctors detect diabetes retinopathy quickly and accurately. This system involves a series of digital image processing techniques that can process retinal images into good quality images. In this research, a method to improve the quality of retinal images was designed by comparing the methods for adjusting histogram equalization, contrast stretching, and increasing brightness. The performance of the three methods was evaluated using Mean Square Error (MSE), Peak Signal to Noise Ratio (PSNR), and Signal to Noise Ratio (SNR). Low MSE values and high PSNR and SNR values indicated that the image had good quality. The results of the study revealed that the image was the best to use, as evidenced by the lowest MSE values and the highest SNR and PSNR values compared to other techniques. It indicated that adaptive histogram equalization techniques could improve image quality while maintaining its information.

Preliminary study of improved median filter using adaptively mask size in light microscopic image

Microscopy ◽  
2020 ◽  
Vol 69 (1) ◽  
pp. 31-36
Author(s):  
Ji-Youn Kim ◽  
Youngjin Lee
Keyword(s):  
Image Quality ◽  
Coefficient Of Variation ◽  
Signal To Noise Ratio ◽  
Median Filter ◽  
Microscopic Image ◽  
Signal To Noise ◽  
Mask Size ◽  
Preliminary Study ◽  
Noise Ratio ◽  
Image Details

Abstract This study aimed to develop and evaluate an improved median filter (IMF) with an adaptive mask size for light microscope (LM) images. We acquired images of the mouse first molar using a LM at 100× magnification. The images obtained using our proposed IMF were compared with those from a conventional median filter. Several parameters such as the contrast-to-noise ratio, coefficient of variation, no-reference assessments and peak signal-to-noise ratio were employed to evaluate the image quality quantitatively. The results demonstrated that the proposed IMF could effectively de-noise the LM images and preserve the image details, achieving a better performance than the conventional median filter.

scholarly journals Image multiplexing using residue number system coding over MIMO-OFDM communication system

2019 ◽  
Vol 9 (6) ◽  
pp. 4815
Author(s):  
Mohamed Ibrahim Youssif ◽  
Amr ElSayed Emam ◽  
Mohamed Abd ElGhany
Keyword(s):  
Image Quality ◽  
Communication System ◽  
Signal To Noise Ratio ◽  
Image Transmission ◽  
Number System ◽  
Residue Number System ◽  
Signal To Noise ◽  
Residue Number ◽  
Mimo Ofdm ◽  
Noise Ratio

<p>Image transmission over Orthogonal Frequency-Division Multiplexing (OFDM) communication system is prone to distortion and noise due to the encountered High-Peak-to-Average-Power-Ratio (PAPR) generated from the OFDM block. This paper studies the utilization of Residue Number System (RNS) as a coding scheme for digital image transmission over Multiple-Input-Multiple-Output (MIMO) – OFDM transceiver communication system. The use of the independent parallel feature of RNS, as well as the reduced signal amplitude to convert the input signal to parallel smaller residue signals, enable to reduce the signal PAPR, decreasing the signal distortion and the Bit Error Rate (BER). Consequently, improving the received Signal-to-Noise Ratio (SNR) and enhancing the received image quality. The performance analyzed though BER, and PAPR. Moreover, image quality measurement is achieved through evaluating the Mean Squared Error (MSE), Peak Signal to Noise Ratio (PSNR), and the correlation values between the initial and retrieved images. Simulation results had shown the performance of transmission/reception model with and without RNS coding implementation.</p><p> </p>

The Influence of Alteration of kVp and mAs towards the Image Quality of Acrylic Using CBCT

2019 ◽  
Vol 829 ◽  
pp. 252-257
Author(s):  
Azhari ◽  
Yohanes Hutasoit ◽  
Freddy Haryanto
Keyword(s):  
Image Quality ◽  
Signal To Noise Ratio ◽  
Region Of Interest ◽  
Signal To Noise ◽  
Bite Block ◽  
Significant Difference ◽  
Noise Ratio ◽  
Post Hoc ◽  
Radiograph Image

CBCT is a modernized technology in producing radiograph image on dentistry. The image quality excellence is very important for clinicians to interpret the image, so the result of diagnosis produced becoming more accurate, appropriate, thus minimizing the working time. This research was aimed to assess the image quality using the blank acrylic phantom polymethylmethacrylate (PMMA) (C­5H8O2)n in the density of 1.185 g/cm3 for evaluating the homogeneity and uniformity of the image produced. Acrylic phantom was supported with a tripod and laid down on the chin rest of the CBCT device, then the phantom was fixed, and the edge of the phantom was touched by the bite block. Furthermore, the exposure of the X-ray was executed toward the acrylic phantom with various kVp and mAs, from 80 until 90, with the range of 5 kV and the variation of mA was 3, 5, and 7 mA respectively. The time exposure was kept constant for 25 seconds. The samples were taken from CBCT acrylic images, then as much as 5 ROIs (Region of Interest) was chosen to be analyzed. The ROIs determination was analyzed by using the ImageJ® software for recognizing the influence of kVp and mAs towards the image uniformity, noise and SNR. The lowest kVp and mAs had the result of uniformity value, homogeneity and signal to noise ratio of 11.22; 40.35; and 5.96 respectively. Meanwhile, the highest kVp and mAs had uniformity value, homogeneity and signal to noise ratio of 16.96; 26.20; and 5.95 respectively. There were significant differences between the image uniformity and homogeneity on the lowest kVp and mAs compared to the highest kVp and mAs, as analyzed with the ANOVA statistics analysis continued with the t-student post-hoc test with α = 0.05. However, there was no significant difference in SNR as analyzed with the ANOVA statistic analysis. The usage of the higher kVp and mAs caused the improvement of the image homogeneity and uniformity compared to the lower kVp and mAs.

Quality of Computed Tomography Pulmonary Embolism and Aortic Phase Images Acquired with Power Injection via an Arm Port

2017 ◽  
Vol 22 (2) ◽  
pp. 88-92
Author(s):  
Ryan Verity ◽  
David Leswick ◽  
Brent Burbridge ◽  
Rhonda Bryce ◽  
Hyun Lim
Keyword(s):  
Computed Tomography ◽  
Pulmonary Embolism ◽  
Image Quality ◽  
Thin Section ◽  
Signal To Noise Ratio ◽  
Contrast Injection ◽  
Signal To Noise ◽  
Streak Artifact ◽  
Noise Ratio

Abstract Background: The safety of power-injectable implanted arm ports is well established, but there is insufficient data to conclude that image quality of computed tomography resulting from contrast introduced via the port is of equal quality to images derived from contrast introduced via traditional peripheral access. The objective of this study was to determine whether the image quality of computed tomography pulmonary embolism and computed tomography aorta studies would differ when injecting contrast via an implanted arm port vs a peripheral intravenous site. We hypothesized that injecting via an implanted arm port would produce better-quality images, the result of more appropriate timing and less streak artifact. Methods: Scans from a provincial database search for patients who underwent a computed tomography pulmonary embolism or aorta study with contrast injection via the implanted arm port and thin section images available, were reviewed (pulmonary embolism studies n = 3, aorta studies n = 3). Only a limited number of patients were available for review because there are currently few patients with these ports in place and we limited evaluation to thin section images. Comparison was made with 6 control patients who did not have a port and had received a peripheral arm intravenous contrast injection for these study types. Objective measurements included signal-to-noise ratio and contrast-to-noise ratio of the pulmonary arteries (4 sites) and aorta (2 sites) as appropriate for scan type. Subjective analysis of image quality was performed by 2 radiologists. Results: Although sample size was limited, the implanted arm port group had similar or higher mean signal-to-noise ratio and contrast-to-noise ratio values at all sites. Subjective assessments showed the implanted arm port group to have similar or better opacification and diagnostic confidence; similar or less streak artifact was also observed at each of the sites. Conclusions: These exploratory results suggest that studies with implanted arm port injection can generate high-quality images on both objective and subjective assessment, similar to, or possibly better than, images generated from usual peripheral intravenous access for contrast injection.

scholarly journals Feasibility study of using simultaneous multi-slice RESOLVE diffusion weighted imaging to assess parotid gland tumors: comparison with conventional RESOLVE diffusion weighted imaging

2020 ◽  
Author(s):  
Jia-Suo Jiang ◽  
Liu-Ning Zhu ◽  
Qian Wu ◽  
Yi Sun ◽  
Wei Liu ◽  
...  
Keyword(s):  
Image Quality ◽  
Parotid Gland ◽  
Diffusion Weighted Imaging ◽  
Signal To Noise Ratio ◽  
Anatomical Structure ◽  
Parotid Gland Tumors ◽  
Diffusion Weighted ◽  
Scan Time ◽  
Significant Difference ◽  
Noise Ratio

Abstract Background To evaluate the feasibility of using simultaneous multi-slice (SMS) readout segmentation of long variable echo-trains (RESOLVE) diffusion-weighted imaging (DWI) to assess parotid gland tumors, compared with conventional RESOLVE DWI Methods From September 2018 to December 2018, 20 consecutive patients with parotid tumors who underwent MRI scan for pre-surgery evaluation were enrolled. SMS-RESOLVE DWI and conventional RESOLVE DWI were scanned with matched imaging parameters, respectively. The scan time of two DWI sequences was recorded. Qualitative (anatomical structure differentiation, lesion display, artifact, and overall image quality) and quantitative (apparent diffusion coefficient, ADC; ratio of signal-to-noise ratio, SNR ratio; ratio of contrast-to-noise ratio, CNR ratio) assessments of image quality were performed, and compared between SMS-RESOLVE DWI and conventional RESOLVE DWI. Paired t-test was used for statistical analyses. Results The scan time was 3 minutes and 41 seconds for SMS-RESOLVE DWI, and 5 minutes and 46 seconds for conventional RESOLVE DWI. SMS-RESOLVE DWI produced similar qualitative image quality with RESOLVE DWI (anatomical structure differentiation, P = 0.164; lesion display, P = 0.193; artifact, P = 0.330; overall image quality, P = 0.083). Meanwhile, there were no significant difference on ADCLesion (P = 0.298), ADCMasseter (P = 0.122), SNR ratio (P = 0.584) and CNR ratio (P = 0.217) between two DWI sequences. Conclusion Compared with conventional RESOLVE DWI, SMS-RESOLVE DWI could provide comparable image quality using markedly reduced scan time. SMS could increase the clinical usability of RESOLVE technique for DWI of parotid gland.

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