scholarly journals Effects of recombination on the evolvability, genetic diversity and mutational robustness of neutrally evolving populations

2022 ◽  
Author(s):  
Joachim Krug ◽  
Alexander Klug
Keyword(s):  
Genetic Diversity ◽  
Genetic Drift ◽  
Experimental Research ◽  
Theoretical Models ◽  
The Other ◽  
Complex Behavior ◽  
Mutational Robustness ◽  
Comprehensive Overview ◽  
Trade Off ◽  
The One

Many effects attributed to recombination have been invoked to explain the advantage of sex. The most prominent arguments focus on either evolvability, genetic diversity, or mutational robustness to justify why the benefit of recombination overcomes its costs, with partially contradicting results. As a consequence, understanding which aspects of recombination are most important in a given situation remains an open problem for theoretical and experimental research. In this study, we focus on finite populations evolving on neutral networks, which already display remarkably complex behavior. We aim to provide a comprehensive overview of the effects of recombination by jointly considering different measures of evolvability, genetic diversity, and mutational robustness over a broad parameter range, such that many evolutionary regimes are covered. We find that several of these measures vary non-monotonically with the rates of mutation and recombination. Moreover, the presence of lethal genotypes that introduce inhomogeneities in the network of viable states qualitatively alters the effects of recombination. We conclude that conflicting trends induced by recombination can be explained by an emerging trade-off between evolvability and genetic diversity on the one hand, and mutational robustness and fitness on the other. Finally, we discuss how different implementations of the recombination scheme in theoretical models can affect the observed dependence on recombination rate through a coupling between recombination and genetic drift.

The Problem of the Typology of Rationality in Muslim Culture

2019 ◽  
Vol 62 (6) ◽  
pp. 88-99
Author(s):  
Andrey A. Lukashev
Keyword(s):  
Modern Philosophy ◽  
Theoretical Basis ◽  
Theoretical Models ◽  
The Other ◽  
Common Denominator ◽  
Islamic Culture ◽  
The Common ◽  
Per Se ◽  
The One ◽  
Muslim Culture

The typology of rationality is one of major issues of modern philosophy. In an attempt to provide a typology to Oriental materials, a researcher faces additional problems. The diversity of the Orient as such poses a major challenge. When we say “Oriental,” we mean several cultures for which we cannot find a common denominator. The concept of “Orient” involves Arabic, Indian, Chinese, Turkish and other cultures, and the only thing they share is that they are “non-Western.” Moreover, even if we focus just on Islamic culture and look into rationality in this context, we have to deal with a conglomerate of various trends, which does not let us define, with full confidence, a common theoretical basis and treat them as a unity. Nevertheless, we have to go on trying to find common directions in thought development, so as to draw conclusions about types of rationality possible in Islamic culture. A basis for such a typology of rationality in the context of the Islamic world was recently suggested in A.V. Smirnov’s logic of sense theory. However, actual empiric material cannot always fit theoretical models, and the cases that do not fit the common scheme are interesting per se. On the one hand, examination of such cases gives an opportunity to specify certain provisions of the theory and, on the other hand, to define the limits of its applicability.

scholarly journals PAKARTOJIMAS IR NIHILIZMAS

Problemos ◽  
2013 ◽  
Vol 84 ◽  
pp. 46-59
Author(s):  
Rita Šerpytytė
Keyword(s):  
Theoretical Models ◽  
The Other ◽  
Philosophical Tradition ◽  
Western Tradition ◽  
Other Hand ◽  
Text Fragment ◽  
Western Philosophical Tradition ◽  
Universal Structure ◽  
The One

Straipsnio tikslas yra atskleisti Vakarų filosofijos tradicijoje savitai įsitvirtinusios patyrimo struktūros, įvardijamos pakartojimu, nihilistinę prasmę. Šioje hermeneutinėje analizėje, viena vertus, re­miamasi tam tikra nihilizmo samprata, numatančia du nihilizmo teorinius modelius – nihilizmą, parem­tą Überwindung teorija, ir nihilizmą, paremtą différance idėja. Kita vertus, remiamasi tam tikru („onto-teologiniu“) pretekstu Vakarų mąstymo tradicijoje atpažįstant pakartojimo struktūrą – Pauliaus Laiško efeziečiams Ef. I, 10 teksto fragmentu, laikomu paradigmine pakartojimo struktūros išsklaida. Herme­neutinė analizė projektuojama į Kierkegaardo ir Agambeno filosofiją, atskirus jų mąstyme atpažįstamus pakartojimo invariantus atskleidžiant kaip minėto Pauliaus Laiško fragmento eksplozijos atvejus. Ke­liamas klausimas, kas yra pakartojimas, kur slypi jo negatyvumas ir kaip pasirodo jo nihilistinė prasmė? Kaip šioje negatyvumo ir nihilizmo atskleistyje „tarpininkauja“ différance? Straipsnyje parodoma, jog skirtis kaip neigimo judesys, atstovaujantis nihilistinei logikai, gali būti traktuojamas ir vien formaliai, ir realiai. Skirties kaip realaus neigimo traktavimas Kierkegaardo ir Agambeno mąstyme atitinka pačios patirties struktūros – pakartojimo – ontologinį (tikrovišką) įšaknytumą.Pagrindiniai žodžiai: pakartojimas, nihilizmas, différance, negatyvumas, laikasPakartojimas ir nihilizmasRita Šerpytytė   AbstractThe purpose of this article is to reveal the nihilistic sense of an experiential structure, which has been distinctively rooted in Western philosophical tradition. On the one hand, this hermeneutical analysis will be based on a certain conception of nihilism presupposing two theoretical models of nihilism – nihilism, which refers to the theory of Überwindung, and nihilism associated with the idea of différance. On the other hand, it builds upon a certain (the so-called “onto-theological”) pretext, which might be used for recognition of the structure of repetition in Western tradition of thinking, – i.e. the fragment of a text from St. Paul’s Letter to the Ephesians Eph. I, 10 – the paradigmatic passage proposing this universal structure of repetition. Focused both on philosophy of Kierkegaard and Agamben, hermeneutical analysis will aim to disclose the separate invariants of such repetition as cases of explosion of the mentioned text fragment. The question is raised – what is repetition? Where does its negativity lie? How does its nihilistic sense appear? How does the différance mediate in this process of revealing of negativity and nihilism? The article argues that difference, as a motion of negation representing nihilistic logic, can be treated both in merely formal and in a realistic way. The treating of différance as real denying in Kierkegaard’s and Agamben’s thinking corresponds to the ontological rootedness of the very structure of experience – repetition.Keywords: repetition, nihilism, différance, negativity, time

scholarly journals Plasmodium infection decreases fecundity and increases survival of mosquitoes

2012 ◽  
Vol 279 (1744) ◽  
pp. 4033-4041 ◽  
Author(s):  
J. Vézilier ◽  
A. Nicot ◽  
S. Gandon ◽  
A. Rivero
Keyword(s):  
Life History ◽  
Insecticide Resistance ◽  
Life History Traits ◽  
Experimental System ◽  
Adaptive Strategy ◽  
Genetic Variations ◽  
The Other ◽  
Plasmodium Infection ◽  
Trade Off ◽  
The One

Long-lived mosquitoes maximize the chances of Plasmodium transmission. Yet, in spite of decades of research, the effect of Plasmodium parasites on mosquito longevity remains highly controversial. On the one hand, many studies report shorter lifespans in infected mosquitoes. On the other hand, parallel (but separate) studies show that Plasmodium reduces fecundity and imply that this is an adaptive strategy of the parasite aimed at redirecting resources towards longevity. No study till date has, however, investigated fecundity and longevity in the same individuals to see whether this prediction holds. In this study, we follow for both fecundity and longevity in Plasmodium- infected and uninfected mosquitoes using a novel, albeit natural, experimental system. We also explore whether the genetic variations that arise through the evolution of insecticide resistance modulate the effect of Plasmodium on these two life-history traits. We show that (i) a reduction in fecundity in Plasmodium- infected mosquitoes is accompanied by an increase in longevity; (ii) this increase in longevity arises through a trade-off between reproduction and survival; and (iii) in insecticide-resistant mosquitoes, the slope of this trade-off is steeper when the mosquito is infected by Plasmodium (cost of insecticide resistance).

Narrative in Form: A topological study of meaning in transmedial narratives

2016 ◽  
Vol 21 (3) ◽  
pp. 260-272 ◽  
Author(s):  
Marinos Giannoukakis
Keyword(s):  
Theoretical Models ◽  
The Other ◽  
Structure And Dynamics ◽  
Morphology And Structure ◽  
Art Forms ◽  
Multimedia Art ◽  
The One ◽  
Insight Into

This article is an attempt to demonstrate the relation between appreciation of morphology and structure in form on the one hand, with higher symbolic structures – crucial for meaning formation routines – on the other, and to evaluate their significance in transmedial narratives, primarily in the case of media-based artworks. The use of catastrophe theoretical models to classify forms, their structure and dynamics is proposed, and the question of how these models can give us insight into the meaning that is carried through transmedial narratives (referential or abstract) is examined. Finally, the value of these insights for the composition and practice-based analysis of multimedia art forms is demonstrated.

scholarly journals Working-Class Standards of living in Three Lancashire Towns, 1890–1914

1982 ◽  
Vol 27 (1) ◽  
pp. 43-65 ◽  
Author(s):  
Elizabeth Roberts
Keyword(s):  
Working Class ◽  
Theoretical Models ◽  
Poverty Line ◽  
The Other ◽  
Real Wages ◽  
Wage Rates ◽  
Standards Of Living ◽  
Employment Of Women ◽  
The One ◽  
The Cost

This article examines some aspects of working-class standards of living in three Lancashire towns, Barrow-in-Furness, Lancaster and Preston, in the period 1890 to 1914. By looking on one hand at a number of externally determined factors, such as real wages and the cost of living, and on the other at the strategies with which the working-class families attempted to maximise their standards of living, an assessment is made of the relative success of these various strategies, particularly at periods when wages were on or below the poverty line. Particular stress is laid on evidence from Preston, in part because it has not previously been reported, but also because there appear to be a number of significant variations between Preston on the one hand, and Barrow and Lancaster on the other, when placed in apparently similar intrinsic conditions and in comparatively close geographical proximity to each other. These variations underline the extent to which generalisations derived principally from statistical data may be misleading, and also the importance of looking at individual discrete communities before relying on theoretical models of the relationship between, for example, income from primary employment and standards of living. If it is possible to demonstrate that working-class people in some towns were more successful than their near neighbours in combating poverty, we need to identify the reasons for these differences. Factors discussed include the economy of Preston compared with Barrow and Lancaster, comparisons of wage rates, the employment of women and its effects, and diets (including the use of allotments), the effects of drinking, as well as a look at possible negative factors, such as family size, and housing and hygiene.

Decreasing the Adhesion Effect of Surfaces Using Graphite Pellicle Deposition through Electric Discharges in Pulse

2014 ◽  
Vol 1036 ◽  
pp. 172-177 ◽  
Author(s):  
Pavel Topala ◽  
Vitalie Besliu ◽  
Laurentiu Marin
Keyword(s):  
Experimental Research ◽  
Metal Surfaces ◽  
The Other ◽  
Electric Discharges ◽  
Polyurethane Adhesive ◽  
Test Pieces ◽  
Other Hand ◽  
The One ◽  
Adhesion Effect

The paper aims at studying the phenomenon of adhesion between the graphite pellicles deposited through electric discharges in pulse (EDI) with metal surfaces subjected to processing on the one hand and on the other hand the adhesion of this pellicle with a polyurethane adhesive. Experimental research has shown that, when the surfaces are not treated, the shear occurs in the adhesive, when the test pieces are covered with graphite pellicles the shear occurs on the surface that separates the pellicle from the adhesive. It has been stated experimentally that graphite pellicles deposited through electric discharges in pulse decrease the adhesion between the mating surfaces by at least 40% compared to the not treated surfaces.

Optimal Contracting Model in a Social Environment and Trust-Related Psychological Costs

2013 ◽  
Vol 13 (1) ◽  
pp. 271-284 ◽  
Author(s):  
Suren Basov ◽  
M. Ishaq Bhatti
Keyword(s):  
Social Norms ◽  
Social Environment ◽  
Point Of View ◽  
The Other ◽  
Trade Off ◽  
Optimal Contracting ◽  
The Social ◽  
The One ◽  
Contracting Model

AbstractMost research in contract theory concentrated on the role of incentives in shaping individual behavior. Recent research suggests that social norms also play an important role. From a point of view of a mechanism designer (a principal, a government, and a bank), responsiveness of an agent to the social norms is both a blessing and a curse. On the one hand, it provides the designer with extra instruments, while on the other it puts restrictions on how these new and the more conventional instruments can be used. The main objective of this paper is to investigate this trade-off and study how it shapes different contracts observed in the real world. We consider a model in which agent’s cost of cheating is triggered by the principal’s show of trust. We call such behavior a norm of honesty and trust and show that it drives incentives to be either low powerful or high powerful, eliminating contracts with medium powerful incentives.

A Dynamic Model Balancing User Control and Workload in Automatic and Adaptive Systems

2007 ◽  
Vol 51 (4) ◽  
pp. 186-190
Author(s):  
Shelley Roberts ◽  
Avi Parush
Keyword(s):  
User Interfaces ◽  
Adaptive Systems ◽  
Interactive Systems ◽  
The Other ◽  
Dynamic Changes ◽  
Trade Off ◽  
Controlled Systems ◽  
Adaptive User Interfaces ◽  
Interface Adaptation ◽  
The One

Current interactive systems are criticized for having complex interfaces that overload users with information. Two possible solutions to manage overload are automatic interfaces that augment user capabilities, and user-controlled systems that provide support. These two types of interfaces introduce a trade-off: On the one hand, automatic interfaces alleviate workload but create performance problems associated with the absence of control. On the other hand, user-controlled interfaces afford users more control, which may come with additional workload. Based on the analysis of adaptive user interfaces and automation, a model is proposed where automatic and user interface adaptation are in a multidimensional and continuum-based space, allowing for modelling dynamic changes to the roles the human and machine play at various stages of interaction.

scholarly journals On the One Hand or on the Other: Trade-Off in Timing Precision in Bimanual Musical Scale Playing

2019 ◽  
Vol 15 (3) ◽  
pp. 216-224
Author(s):  
Floris Tijmen van Vugt ◽  
Eckart Altenmüller
Keyword(s):  
The Other ◽  
Musical Scale ◽  
Trade Off ◽  
Timing Precision ◽  
The One

Authority

2017 ◽  
Author(s):  
Alfonso Troisi
Keyword(s):  
Divergent Thinking ◽  
The Other ◽  
Trade Off ◽  
Distinctive Features ◽  
Positive Effects ◽  
Extreme Dependence ◽  
Personality Changes ◽  
The Social ◽  
The One ◽  
Average Individual

Evolving organisms must balance the need to change at an appropriate rate in response to varying environmental conditions against the need to maintain a functioning phenotype. This trade-off between conservatism and adaptability, between stability and exploration, has an interesting analogue at the social and cultural level. On the one hand, humans are characterized by an extreme dependence on culturally transmitted information, and deference to the group norm is the average individual behavior in human societies. On the other hand, innovation and openness to experience are distinctive features of cultural revolutions. This chapter focuses on the biology of conformity and innovation, discussing a variety of related topics, including personality changes with aging, the neural bases of divergent thinking, the positive effects of conservatism on intragroup cohesion, and the link between creativity and psychosis.

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