Zero-Crossing-Based Bio-Engineered Sensor

Author(s):  
Qijun Liu ◽  
Arslan Riaz ◽  
Timur Zirtiloglu ◽  
Maria Eugenia Inda ◽  
Miguel Jimenez ◽  
...  
Keyword(s):  
Author(s):  
Ahmad Idil Abd Rahman ◽  
◽  
Muhammad Akmal Bahari ◽  
Zikri Abadi Baharudin ◽  
◽  
...  

Author(s):  
Pratik S Mehta ◽  
Pratik R. Patel ◽  
Rajesh R Parmar ◽  
M M K Modasiya ◽  
Dushyant A Shah

A novel, simple, accurate, sensitive, precise and economical derivative spectroscopic method was developed and validated for the determination of cefadroxil and probenecid in synthetic mixture. First order derivative spectroscopy method was adopted to eliminate spectral interference. The method obeys Beer’s Law in concentration ranges of 4-36 μg/ml for cefadroxil and of 5-25 μg/ml of probenecid. The zero crossing point for cefadroxil and probenecid was 260 nm and 237.8 nm respectively in 0.1N HCl. The method was validated in terms of accuracy, precision, linearity, limits of detection, limits of quantitation. This method has been successively applied to synthetic mixture and no interference from the synthetic mixture’s excipients was found.   


Author(s):  
Lei Qi ◽  
Xilin Chen ◽  
Xinyuan Qu ◽  
Liangtao Zhan ◽  
Xiangyu Zhang ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jan Pyrzowski ◽  
Jean- Eudes Le Douget ◽  
Amal Fouad ◽  
Mariusz Siemiński ◽  
Joanna Jędrzejczak ◽  
...  

AbstractClinical diagnosis of epilepsy depends heavily on the detection of interictal epileptiform discharges (IEDs) from scalp electroencephalographic (EEG) signals, which by purely visual means is far from straightforward. Here, we introduce a simple signal analysis procedure based on scalp EEG zero-crossing patterns which can extract the spatiotemporal structure of scalp voltage fluctuations. We analyzed simultaneous scalp and intracranial EEG recordings from patients with pharmacoresistant temporal lobe epilepsy. Our data show that a large proportion of intracranial IEDs manifest only as subtle, low-amplitude waveforms below scalp EEG background and could, therefore, not be detected visually. We found that scalp zero-crossing patterns allow detection of these intracranial IEDs on a single-trial level with millisecond temporal precision and including some mesial temporal discharges that do not propagate to the neocortex. Applied to an independent dataset, our method discriminated accurately between patients with epilepsy and normal subjects, confirming its practical applicability.


Metals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 465
Author(s):  
Friedhelm Frerichs ◽  
Yang Lu ◽  
Thomas Lübben ◽  
Tim Radel

During many manufacturing processes for surface treatment of steel components heat will be exchanged between the environment and the workpiece. The heat exchange commonly leads to temperature gradients within the surface near area of the workpiece, which involve mechanical strains inside the material. If the corresponding stresses exceed locally the yield strength of the material residual stresses can remain after the process. If the temperature increase is high enough additionally phase transformation to austenite occurs and may lead further on due to a fast cooling to the very hard phase martensite. This investigation focuses on the correlation between concrete thermal loads such as temperature and temperature gradients and resulting modifications such as changes of the residual stress, the microstructure, and the hardness respectively. Within this consideration the thermal loads are the causes of the modifications and will be called internal material loads. The correlations between the generated internal material loads and the material modifications will be called Process Signature. The idea is that Process Signatures provide the possibility to engineer the workpiece surface layer and its functional properties in a knowledge-based way. This contribution presents some Process Signature components for a thermally dominated process with phase transformation: laser hardening. The target quantities of the modifications are the change of the residual stress state at the surface and the position of the 1st zero-crossing of the residual stress curve. Based on Finite Element simulations the internal thermal loadings during laser hardening are considered. The investigations identify for the considered target quantities the maximal temperature, the maximal temperature gradient, and the heating time as important parameters of the thermal loads.


Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1310
Author(s):  
Andreu Salcedo-Bosch ◽  
Francesc Rocadenbosch ◽  
Miguel A. Gutiérrez-Antuñano ◽  
Jordi Tiana-Alsina

This work proposes a new wave-period estimation (L-dB) method based on the power-spectral-density (PSD) estimation of pitch and roll motional time series of a Doppler wind lidar buoy under the assumption of small angles (±22 deg) and slow yaw drifts (1 min), and the neglection of translational motion. We revisit the buoy’s simplified two-degrees-of-freedom (2-DoF) motional model and formulate the PSD associated with the eigenaxis tilt of the lidar buoy, which was modelled as a complex-number random process. From this, we present the L-dB method, which estimates the wave period as the average wavelength associated to the cutoff frequency span at which the spectral components drop off L decibels from the peak level. In the framework of the IJmuiden campaign (North Sea, 29 March–17 June 2015), the L-dB method is compared in reference to most common oceanographic wave-period estimation methods by using a TriaxysTM buoy. Parametric analysis showed good agreement (correlation coefficient, ρ = 0.86, root-mean-square error (RMSE) = 0.46 s, and mean difference, MD = 0.02 s) between the proposed L-dB method and the oceanographic zero-crossing method when the threshold L was set at 8 dB.


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