scholarly journals An initial research on Halstead's technique for pattern similarity relationship study

2018 ◽  
Author(s):  
Yulius Denny Prabowo ◽  
Harco Leslie Hendric Spits Warnas ◽  
Ford Lumban Gaol ◽  
Edi Abdurachman ◽  
Benfano Soewito
Keyword(s):  
Similarity Relationship ◽  
Pattern Similarity ◽  
Relationship Study ◽  
Initial Research

Introduction

2018 ◽  
Author(s):  
Peter Hopkins
Keyword(s):  
Final Section ◽  
Short Note ◽  
Current Situation ◽  
Research Projects ◽  
Everyday Lives ◽  
Early Settlement ◽  
The Everyday ◽  
Initial Research

The chapters in this collection explore the everyday lives, experiences, practices and attitudes of Muslims in Scotland. In order to set the context for these chapters, in this introduction I explore the early settlement of Muslims in Scotland and discuss some of the initial research projects that charted the settlement of Asians and Pakistanis in Scotland’s main cities. I then discuss the current situation for Muslims in Scotland through data from the 2011 Scottish Census. Following a short note about the significance of the Scottish context, in the final section, the main themes and issues that have been explored in research about Muslims in Scotland.

Children show adult-like hippocampal pattern separation for familiar but not novel events

2020 ◽  
Author(s):  
Susan L. Benear ◽  
Elizabeth A. Horwath ◽  
Emily Cowan ◽  
M. Catalina Camacho ◽  
Chi Ngo ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Developmental Change ◽  
Pattern Separation ◽  
Developmental Changes ◽  
Similarity Analysis ◽  
Separation Processes ◽  
Parahippocampal Cortex ◽  
Pattern Similarity

The medial temporal lobe (MTL) undergoes critical developmental change throughout childhood, which aligns with developmental changes in episodic memory. We used representational similarity analysis to compare neural pattern similarity for children and adults in hippocampus and parahippocampal cortex during naturalistic viewing of clips from the same movie or different movies. Some movies were more familiar to participants than others. Neural pattern similarity was generally lower for clips from the same movie, indicating that related content taxes pattern separation-like processes. However, children showed this effect only for movies with which they were familiar, whereas adults showed the effect consistently. These data suggest that children need more exposures to stimuli in order to show mature pattern separation processes.

On Advisor Education: Evaluating Departmental Training and Professional Development Practices of Academic Staff in a Japanese University

Relay Journal ◽  
2019 ◽  
pp. 271-291
Author(s):  
Huw Davies
Keyword(s):  
Professional Development ◽  
Academic Staff ◽  
Realist Evaluation ◽  
International Studies ◽  
Peer Observation ◽  
Research Issue ◽  
Training Aids ◽  
The People ◽  
The University ◽  
Initial Research

This study is an evaluation of the professional development (PD) programme for learning advisors employed in the self-access centre at Kanda University of International Studies in Japan. The research issue investigated was whether the PD activities of advisors allow them to provide appropriate support to students at the University. The implementation of policies, the people and the setting were all considered in building an understanding of what may make the programme work. The framework used to understand this programme is realist evaluation (Pawson & Tilley, 1997), in which theories related to the initial research issue were refined and developed to offer new perspectives. Results suggest that initial training aids advisors in supporting students, but that future implementation decisions are needed for the mentoring element of the programme and on whether more peer observation should take place. The implication that informal discussion among the workgroup and the freedom to choose personal PD journeys are fundamental drivers of effective practice is a finding that may be applied to other teacher and advisor education settings.

Corrosion of Welded Metal Structures of Mining Equipment

2018 ◽  
Vol 69 (9) ◽  
pp. 2563-2566
Author(s):  
Dan Dobrota
Keyword(s):  
Carbon Concentration ◽  
Welded Joints ◽  
Construction Material ◽  
Working Environment ◽  
Mining Equipment ◽  
Metal Structures ◽  
Corrosion Phenomenon ◽  
Welding Regime ◽  
New Material ◽  
Initial Research

Mining equipment made of welded metal structures is strongly affected by the corrosion phenomenon due to the working conditions. Initial research has shown that the corrosion phenomenon is most pronounced in the area of cross-welded joints and welded T-shaped joints. In the researches, there was made a chemical analysis of the welded construction material used respectively of the new material and it was observed a reduction in carbon concentration in the material used, but also a substantial increase in the sulfur concentration compared to the new material. The pronounced corrosion of the metallic structure is influenced by the chemical composition change because the sulfur is a grafitizing and weakening element, and the decrease in carbon concentration causes a decrease in corrosion resistance. Also, the pronounced corrosion is due to the action of sulfurous acid (H2SO3) and hydrogen sulfide (H2S), elements that are present in the working environment of welded constructions. In order to achieve a reduction in the corrosion phenomenon, it is very important that the welded joints are made using the optimal parameters of the welding regime so as to obtain metallographic structure with finer granulations.

Naldemedine: Peripherally Acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects

2020 ◽  
Vol 20 (31) ◽  
pp. 2830-2842
Author(s):  
Masanao Inagaki ◽  
Toshiyuki Kanemasa ◽  
Takaaki Yokota
Keyword(s):  
Adverse Effects ◽  
Adverse Events ◽  
Severe Pain ◽  
Lead Compound ◽  
Inhibitory Effects ◽  
Pharmacokinetic Profiles ◽  
Structure Activity ◽  
The Usa ◽  
Relationship Study ◽  
The Eu

Opioids are widely used for pain management in moderate-to-severe pain. However, opioids are associated with adverse events, such as constipation and emesis/vomiting. To reduce these undesired effects, a structure–activity relationship study of morphinan derivatives was conducted, and a promising lead compound with inhibitory effects on opioid receptors was obtained. Further improvement in the potency and pharmacokinetic profiles of the lead compound led to the discovery of naldemedine, which showed anti-constipation and anti-emetic effects against these adverse events that were induced by morphine without influencing morphine’s analgesic effect. Naldemedine was launched in Japan and the USA in 2017 and in the EU in 2019, for treating opioid-induced constipation.

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