Diagnostic Accuracy of Smartphone connected Electrophysiological Biosensors for Prediction of Blood Glucose Level in a Type-2 Diabetic Patient using Machine Learning: A Pilot Study

2021 ◽  
pp. 1-1
Author(s):  
Mohammed Zubair M. Shamim ◽  
Sattam Alotaibi ◽  
Hany S. Hussein ◽  
Mohammed Farrag ◽  
Mohammad Shiblee
2007 ◽  
Vol 7 (1) ◽  
pp. 91-93 ◽  
Author(s):  
Kenzo Oba ◽  
Yuki Inuzuka ◽  
Naoko Yamashita-Onodera ◽  
Kentaro Watanabe ◽  
Noriaki Matsumura ◽  
...  

2017 ◽  
Vol 16 (4) ◽  
pp. 148
Author(s):  
Tripathi Nagja ◽  
Vimal Kumar ◽  
Acharya Sanjeev

The aim of the present study was to determine the anti-diabetic activity of a polyherbal formulation in streptozotocin induced type 2 diabetic rats. The hydroalcoholic extracts of Eugenia jambolana, Gymnema sylvestre, Momordica charantia and Andrographis paniculata and sodhana processed extract of Myristica fragrans were prepared. The 2 day old neonatal rats were injected with 90 mg/kg of streptozotocin intraperitoneally to induce type 2 diabetes. After six weeks of streptozotocin injection, polyherbal formulation was daily administered at a dose of 400 mg/kg body weight to diabetic rats for a period of 28 days. Blood samples were collected from the retro orbital plexus of the eye and blood glucose level was estimated by glucose oxidase-peroxidase method. The study indicated that polyherbal formulation at a dose of 400 mg/kg body weight showed significant decline (p<0.001) in blood glucose level.


2005 ◽  
Vol 53 (4) ◽  
pp. 959-963 ◽  
Author(s):  
Tozo Nishiyama ◽  
Tatsumasa Mae ◽  
Hideyuki Kishida ◽  
Misuzu Tsukagawa ◽  
Yoshihiro Mimaki ◽  
...  

Author(s):  
Firmin Sylva Barboza ◽  
Madièye Sène ◽  
Dominique Doupa ◽  
Malick Ba ◽  
Alassane Wélé ◽  
...  

The purpose of this study is to investigate the effects of total methanol leaf-extract of Dialium guineense (Cesalpiniaceae) and its fractions on blood glucose in rat. The fractions of methanol extract were obtained by chromatography Sephadex LH 20 gel, numbered F1 to F5. Experiments were performed in normoglycemic, glucose tolerance test, and type 2 diabetic rats. The total methanol leaf-extract (300 mg/kg, per os), induced a significant increase of blood glucose level in normoglycemic rats (2.27±0.12 vs 0.94±0.03 g/L) (p<0.05, n=5). F1 and F2 fractions (100 mg/kg, per os) increased the blood glucose level. Glycaemia respectively varied from 0.90 ± 0.03 to 2. 28 ± 0.22 g/L and 0.91 ± 0.03 to 1.43 ± 0.04 g /L (p<0.05, n=5). However, F5 fraction (300 mg/kg, per os), induced hypoglycemia (0.61 ± 0.01 vs 0. 80 ± 0.03 g/L) (p<0.05, n=5). F5 fraction prevented the pic of hyperglycemia caused by glucose (4 g/kg, per os). In type 2 diabetic rats, the daily oral administration of F5 fraction (300 mg/kg) induced an anti-hyperglycemic effect (1.28 ± 0.15 vs 4.48 ± 0.08 g/L). Fractionation by gel permeation chromatography allowed to highlight the presence of compounds both hyper-and hypoglycemic in total methanol leaf-extract of D. guineense. The lack of hypoglycemic effect in normoglycemic rats of total methanol leaf-extract, could respectively be related to the presence of both hyper- and hypoglycemic compounds in F1 and F5 fractions, which induced opposite effects.


2017 ◽  
Vol 12 (4) ◽  
pp. 359
Author(s):  
Lai Wang ◽  
Debmalya Roy ◽  
Sen Sen Lin ◽  
Sheng Tao Yuan ◽  
Li Sun

<p class="Abstract">The aim of this study was to investigate the hypoglycemic effect of Camellia chrysantha using type 2 diabetic mice model. The ethyl acetate/dichloromethane extract exhibited the most effective hypoglycemic effect. Compared to model group, all the three groups of C. chrysantha extracts significantly improved the mice’s behavioral performance, weight, reduced water and food intake. The ethyl acetate/dichloromethane extract of C. chrysantha significantly reduced the blood glucose level in the first week after administration and the crude extract also showed a significant effect after longer time administration. All the three extracts reduced the fasting blood glucose level to a certain extent and ethyl acetate/dichloromethane extract exhibited most significant effect among all the three extracts.</p><p><strong>Video Clip of Methodology</strong>:</p><p>1 min 31 sec   <a href="https://www.youtube.com/v/X_H_vaA7MgE">Full Screen</a>   <a href="https://www.youtube.com/watch?v=X_H_vaA7MgE">Alternate</a></p>


2017 ◽  
Vol 14 (2) ◽  
pp. 77 ◽  
Author(s):  
Azkia Nastiti ◽  
Agnes Murdiati ◽  
Y. Marsono

Jack bean is one of local beans known to contain natural resistant starch (RS) content. To increase its RS content, four cycle autoclaving – cooling treatment modification was applied to generate resistant starch type 4 (RS-4) which refers to RS obtained from modification. RS is able to improve blood glucose level of diabetic individuals. This research aimed to measure the effect of jack bean autoclaved – cooled starch (AC starch) diet on blood glucose level and digesta characteristics of type-2 diabetic Sprague Dawley rats in vivo. Bioassay analyses showed that jack bean AC starch consumption decreased blood glucose level at range of 96.05mg/dl – 135.97mg/dl. The diet was also able to increase short chain fatty acids (SCFA) production in form of acetic acid, propionic acid, and butiric acid, to increase total weight and moisture content of digesta, while reduce digesta pH, as well as to inhibit glucose absorption. Diet of 50% high RS jack bean AC starch showed the best results in all glucose metabolism parameters for type-2 diabetic animals. 


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