The relationship between pre‐pregnancy dietary patterns adherence and risk of gestational diabetes mellitus in Iran: A case–control study

2019 ◽  
Vol 76 (5) ◽  
pp. 597-603 ◽  
Author(s):  
Maryam Asadi ◽  
Maedeh Shahzeidi ◽  
Azadeh Nadjarzadeh ◽  
Hadiseh Hashemi Yusefabad ◽  
Anahita Mansoori
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Dietary Patterns ◽  
Case Control Study ◽  
Case Control ◽  
The Relationship ◽  
Control Study

scholarly journals Gestational diabetes mellitus is associated with antenatal hypercoagulability and secondary hyperfibrinolysis: a case control study of Chinese women

2019 ◽  
Author(s):  
Yan Liu ◽  
Xiaofang Sun ◽  
Junxian Tao ◽  
Bin Song ◽  
Wei Wu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Case Control Study ◽  
Chinese Women ◽  
Case Control ◽  
Clot Lysis ◽  
Secondary Hyperfibrinolysis ◽  
The Relationship ◽  
Control Study

Abstract Background : To determine the relationship between gestational diabetes mellitus (GDM) and coagulation/fibrinolysis disorders in antenatal Chinese women . Methods: Case control study. Fifty women had GDM and 132 did not (the NGDM group). Maternal plasma biochemistry and previous medical history were collected from perinatal health records. Antenatal coagulation/fibrinolysis were assessed using thromboelastography and traditional measures, then the relationship between coagulation/fibrinolysis and GDM was analyzed by multiple regression analysis. Results: GDM was significantly associated with higher activated partial thromboplastin time (odds ratio [OR] 1.5, 95% confidence interval [CI] 0.4–2.6); fibrinogen (OR 0.3, 95% CI 0.1–0.6); and percentage reduction in clot lysis after 30 min (OR 1.2, 95% CI 0.2–2.2), after adjustment for potential confounding factors. Both the intraoperative (238.2±71.0 ml vs . 286.0±102.4 ml, P =0.003) and 24-hour after surgery (270.7±99.8 ml vs . 314.7±131.1 ml, P =0.033) blood loss were lower and the prevalence of cesarean delivery (56.0% vs . 37.9%, P =0.027) was higher in the GDM group. There were no significant differences in the prevalence of maternal thrombotic events or maternal body mass before delivery. Conclusions: GDM is significantly associated with hypercoagulability and secondary hyperfibrinolysis in these antenatal Chinese women.

scholarly journals The Relationship between Gestational Diabetes Mellitus and Periodontal Health: A Case-Control Study

2013 ◽  
Vol 2 (2) ◽  
pp. 71-75 ◽  
Author(s):  
Nilsun Bagis ◽  
Hamit Selim Bostanci
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Periodontal Health ◽  
Pocket Depth ◽  
The Relationship ◽  
Control Study

ABSTRACT Introduction Gestational diabetes mellitus (GDM) is carbohydrate intolerance of various degrees occurring or being observed during pregnancy for the first time. The aim of the present study is to investigate the relationship between periodontal health and GDM, which is one of the most important medical complications of pregnancy. Materials and methods One hundred and sixty-five pregnant women, 80 healthy and 85 with gestational diabetes, between the ages of 18 and 30, with a mean age of 25.85 ± 2.96 were included in the study. It was first pregnancy of all individuals and none of them received periodontal treatment 6 months prior to the study. Clinical evaluations were made by using plaque index (PI), gingival index (GI), probing pocket depth, bleeding on probing (BOP) index. Results The results of our study revealed that, compared to healthy pregnant women, the values of body mass index, weight, GI and BOP were significantly higher for women with GDM. How to cite this article Bagis N, Bostanci HS. The Relationship between Gestational Diabetes Mellitus and Periodontal Health: A Case-control Study. Int J Experiment Dent Sci 2013;2(2):71-75.

First trimester prediction of gestational diabetes mellitus using plasma biomarkers: a case-control study

2019 ◽  
Vol 47 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Paula J. Correa ◽  
Pia Venegas ◽  
Yasna Palmeiro ◽  
Daniela Albers ◽  
Gregory Rice ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Case Control Study ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
First Trimester ◽  
Case Control ◽  
Low Density ◽  
Control Study

AbstractObjectivesTo evaluate the first trimester maternal biomarkers for early pregnancy prediction of gestational diabetes mellitus (GDM).MethodsThe study was a case-control study of healthy women with singleton pregnancies at the first trimester carried out at the Obstetrics and Gynecology Unit, Clinica Davila, Santiago, Chile. After obtaining informed consent, peripheral blood samples of pregnant women under 14 weeks of gestation were collected. At 24–28 weeks of pregnancy, women were classified as GDM (n=16) or controls (n=80) based on the results of a 75-g oral glucose tolerance test (OGTT). In all women, we measured concentrations of fasting blood glucose, insulin, glycated hemoglobin, uric acid, cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), triglycerides, aspartate aminotransferase (AST), alanine aminotransferase (ALT), γ-glutamyl transpeptidase (GGT), alkaline phosphatase (AP), sex hormone-binding globulin (SHBG), adiponectin, tissue plasminogen activator (t-PA), leptin and placental growth factor (PGF).ResultsThe GDM group displayed an increased median concentration of cholesterol (P=0.04), triglycerides (P=0.003), insulin (P=0.003), t-PA (P=0.0088) and homeostatic model assessment (HOMA) (P=0.003) and an increased mean concentration of LDL (P=0.009) when compared to the control group. The receiver operating characteristic (ROC) curve for significant variables achieved an area under the curve (AUC) of 0.870, a sensitivity of 81.4% and a specificity of 80.0%. The OGTT was positive for GDM according to the IADPSG (International Diabetes in Pregnancy Study Group) criteria.ConclusionWomen who subsequently developed GDM showed higher levels of blood-borne biomarkers during the first trimester, compared to women who did not develop GDM. These data warrant validation in a larger cohort.

scholarly journals Antidepressant use during pregnancy and the risk of gestational diabetes mellitus: a nested case–control study

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e025908 ◽  
Author(s):  
Maëlle Dandjinou ◽  
Odile Sheehy ◽  
Anick Bérard
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Index Date ◽  
Case Control Study ◽  
Case Control ◽  
Increased Risk ◽  
Antidepressant Use ◽  
Nested Case Control ◽  
Control Study

ObjectivesThe aim of this study was to determine the association between antidepressant (AD) classes, types and duration of use during pregnancy and the risk of gestational diabetes mellitus (GDM).Design and settingA nested case–control study was conducted within the Quebec Pregnancy Cohort (QPC), a Canadian provincial database which includes data on all pregnancies and children in Quebec from January 1998 to December 2015.Primary outcome measuresGestational diabetes mellitus.ParticipantsCases of GDM were identified after week 20 of pregnancy and randomly matched 1:10 to controls on gestational age at index date (ie, calendar date of GDM) and year of pregnancy. AD exposure was assessed by filled prescriptions between the beginning of pregnancy (first day of last menstrual period) and index date. Conditional logistic regression models were used to estimate crude and adjusted odds ratios (aOR).ResultsAmong 20 905 cases and 209 050 matched controls, 9741 (4.2%) women were exposed to ADs. When adjusting for potential confounders, AD use was associated with an increased risk of GDM (aOR 1.19, 95% CI 1.08 to 1.30); venlafaxine (aOR 1.27, 95% CI 1.09 to 1.49) and amitriptyline (aOR 1.52, 95% CI 1.25 to 1.84) were also associated with an increased risk of GDM. Moreover, the risk of GDM was increased with longer duration of AD use, specifically for serotonin norepinephrine reuptake inhibitors, tricyclic ADs and combined use of two AD classes. No statistically significant association was observed for selective serotonin reuptake inhibitors.ConclusionThe findings suggest that ADs—and specifically venlafaxine and amitriptyline—were associated with an increased risk of GDM.

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