Investigation of high‐frequency hearing loss and outer hair cell function of the cochlea in patients with psoriasis: a case–control study

2018 ◽  
Vol 44 (5) ◽  
pp. 520-523 ◽  
Author(s):  
D. Vir ◽  
P. Sharma ◽  
R. Mahajan ◽  
S. Dogra ◽  
J. Bakshi ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
High Frequency ◽  
Case Control Study ◽  
Outer Hair Cell ◽  
Cell Function ◽  
Case Control ◽  
High Frequency Hearing Loss ◽  
Control Study

Evoked response audiometry in scrub typhus: prospective, randomised, case–control study

2011 ◽  
Vol 125 (6) ◽  
pp. 567-571 ◽  
Author(s):  
J S Thakur ◽  
N K Mohindroo ◽  
D R Sharma ◽  
K Soni ◽  
S S Kaushal
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Pure Tone ◽  
Case Control Study ◽  
Scrub Typhus ◽  
Pure Tone Audiometry ◽  
Case Control ◽  
Evoked Response ◽  
Evoked Response Audiometry ◽  
Control Study

AbstractObjective:To investigate the hypothesis of cochlear and retrocochlear damage in scrub typhus, using evoked response audiometry.Study design:Prospective, randomised, case–control study.Methods:The study included 25 patients with scrub typhus and 25 controls with other febrile illnesses not known to cause hearing loss. Controls were age- and sex-matched. All subjects underwent pure tone audiometry and evoked response audiometry before commencing treatment.Results:Six patients presented with hearing loss, although a total of 23 patients had evidence of symmetrical high frequency loss on pure tone audiometry. Evoked response audiometry found significant prolongation of absolute latencies of wave I, III, V, and wave I–III interpeak latency. Two cases with normal hearing had increased interpeak latencies. These findings constitute level 3b evidence.Conclusion:Findings were suggestive of retrocochlear pathology in two cases with normal hearing. In other patients, high frequency hearing loss may have led to altered evoked response results. Although scrub typhus appears to cause middle ear cochlear and retrocochlear damage, the presence of such damage could not be fully confirmed by evoked response audiometry.

scholarly journals Hearing Loss is Associated With Risk of Alzheimer’s Disease: A Case-Control Study in Older People

2015 ◽  
Vol 25 (8) ◽  
pp. 517-521 ◽  
Author(s):  
Shih-Chang Hung ◽  
Kuan-Fu Liao ◽  
Chih-Hsin Muo ◽  
Shih-Wei Lai ◽  
Chia-Wei Chang ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Older People ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Hearing Loss and Associated Factors in Iranian Patients with Type 2 Diabetes: A Case-Control Study

Thrita ◽  
2016 ◽  
Vol 5 (4) ◽  
Author(s):  
Saeed Nouri ◽  
Raika Jamali ◽  
Kurosh Gharagozli ◽  
Mohammad Reza Sharif ◽  
Bardia Jamali
Keyword(s):  
Type 2 Diabetes ◽  
Hearing Loss ◽  
Associated Factors ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Iranian Patients

scholarly journals A Novel Bone Conduction Hearing System May Improve Memory Function in Children with Single Side Hearing loss: A Case-Control Study

2020 ◽  
Vol 16 (2) ◽  
pp. 158-164 ◽  
Author(s):  
Arianna Di Stadio ◽  
◽  
Laura Dipietro ◽  
Antonietta De Lucia ◽  
Valentina Ippolito ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Case Control Study ◽  
Memory Function ◽  
Bone Conduction ◽  
Case Control ◽  
Single Side ◽  
Bone Conduction Hearing ◽  
Control Study ◽  
Hearing System

scholarly journals Associations of Genetic Variation in Glyceraldehyde 3-Phosphate Dehydrogenase Gene with Noise-Induced Hearing Loss in a Chinese Population: A Case-Control Study

2020 ◽  
Vol 17 (8) ◽  
pp. 2899 ◽  
Author(s):  
Liu Wan ◽  
Boshen Wang ◽  
Juan Zhang ◽  
Baoli Zhu ◽  
Yuepu Pu
Keyword(s):  
Hearing Loss ◽  
Genetic Variation ◽  
Chinese Population ◽  
Case Control Study ◽  
Quantitative Polymerase Chain Reaction ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Noise Induced Hearing Loss ◽  
Control Study

Objective: The purpose of this paper was to clarify the association between genetic variation in the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) gene and the risk of noise-induced hearing loss (NIHL). Methods: A case-control study (633 cases and 625 controls) was conducted in this study. Logistic regression was used to analyze the relationships between environmental and individual factors and NIHL. Gene expression levels were compared among each GAPDH rs6489721 genotype and between the case and control groups based on real-time fluorescence quantitative Polymerase Chain Reaction (PCR). Results: The T allele of GADPH rs6489721 was significantly associated with NIHL (odds ratio (OR) = 1.262, 95% confidence interval (CI) (1.066, 1.493), p = 0.006) and showed strong associations in the codominant and dominant models (TT vs. CC: OR = 1.586, 95% CI (1.131, 2.225), p = 0.008; TT vs. TC/CC: OR = 1.391, 95% CI (1.073, 1.804), p = 0.013). The expression level of the TT genotype was significantly higher than that of the CC genotype (p = 0.012), and the expression of the case group was also higher than that of the control group (p = 0.013). Conclusions: The homozygous risk allele (TT) of rs6489721 was associated with an enhanced GAPDH expression, resulting in the development of NIHL in a Chinese population.

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