Dietary Inflammatory Index is Directly Associated with Polycystic Ovary Syndrome: a case‐control study

Polycystic ovary syndrome (PCOS) is a complex hormonal disorder which impair ovarian function. The adherence to healthy dietary patterns and physical exercise are the first line of recommended treatment for PCOS patients, but it is no clear what type of diet is more adequate. In this case-control study, we explore the association between the adherence to five dietary quality indices widely used and PCOS. We enrolled 126 cases of PCOS and 159 controls (Murcia, Spain). Diagnostic of PCOS and its phenotypes were established following the Rotterdam criteria [hyperandrogenism (H), oligoanovulation (O), polycystic ovaries morphology (POM)]. We used a validated food frequency questionnaires to calculate the scores for five dietary indices: alternate Healthy Eating index (AHEI), AHEI-2010, relative Mediterranean Dietary Score (rMED), alternate Mediterranean Dietary Score (aMED) and Dietary Approaches to Stop Hypertension (DASH). We used multivariable logistic regression to estimate adjusted odds ratios and confidence intervals. In the multivariable analysis, AHEI-2010 index was inversely associated with “H+O” PCOS’ phenotype (ORQ3 VS Q1= 0.1; 95% CI :(0.0; 0.9); P for trend= 0.02). In conclusion, we did not find any statistical significative association between dietary indices and total, anovulatory and ovulatory PCOS, but it seems interesting explore these association among the diverse phenotypes of PCOS in studies with higher sample size.

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Dietary diversity score is inversely related to the risk of polycystic ovary syndrome in Tehranian women: a case-control study

Applied Physiology Nutrition and Metabolism ◽

10.1139/apnm-2021-0359 ◽

2021 ◽

pp. 1-6

Author(s):

Sahel Soodi ◽

Seyed Ali Keshavarz ◽

Sedighe Hosseini ◽

Behnood Abbasi

Keyword(s):

Polycystic Ovary Syndrome ◽

Case Control Study ◽

Dietary Diversity ◽

Polycystic Ovary ◽

Case Control ◽

Control Groups ◽

Ovary Syndrome ◽

And Control ◽

The Relationship ◽

Control Study

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is affected by various dietary factors. Therefore, this study aimed to investigate the relationship between dietary diversity score (DDS) and the risk of PCOS. Our case-control study was conducted in the summer and autumn of 2019 in Taleghani and Arash hospitals in Tehran, Iran. A total of 494 participants (203 cases and 291 controls) were included in the study. Thereafter, their demographic information, dietary intake, and anthropometric and physical activity assessments were gathered. A validated semi-quantitative food frequency questionnaire was then used to calculate the DDS by scoring 5 food groups. To evaluate the risk of PCOS in association with DDS, the subjects were categorized based on the quartile cut-off points of the DDS. The mean ± SD age of the participants in both the case and control groups was 28.98 ± 5.43 and 30.15 ± 6.21 years, while mean ± SD body mass index was 25.74 ± 5.44 and 23.65 ± 3.90 kg/m2, respectively. The comparison between the case and control groups indicated that total DDS was 5.19 ± 1.19 for the cases and 5.51 ± 1.19 for the controls. The comparison of DDS in the highest versus the lowest quartiles showed a decreased risk of PCOS (p < 0.05). We demonstrated an inverse association between DDS and PCOS compared with the control group. Furthermore, a higher DDS was significantly associated with a lower risk of PCOS (odds ratio = 0.40). Novelty: This is the first investigation on the relationship between DDS and PCOS. Results depicted an inverse relationship between DDS and PCOS.

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Diet quality scores in relation to fatness and nutritional knowledge in women with polycystic ovary syndrome: case–control study

Public Health Nutrition ◽

10.1017/s1368980020001755 ◽

2020 ◽

pp. 1-10 ◽

Cited By ~ 2

Author(s):

Aleksandra Bykowska-Derda ◽

Magdalena Czlapka-Matyasik ◽

Malgorzata Kaluzna ◽

Marek Ruchala ◽

Katarzyna Ziemnicka

Keyword(s):

Polycystic Ovary Syndrome ◽

Diet Quality ◽

Case Control Study ◽

Dietary Habits ◽

Polycystic Ovary ◽

Case Control ◽

Healthy Diet ◽

Nutritional Knowledge ◽

Ovary Syndrome ◽

Control Study

Abstract Objective: The purpose of the study was to analyse the dietary habits identified by diet quality scores (DQS) in the scope of body fatness (BF) and nutritional knowledge (NK) of polycystic ovary syndrome (PCOS) women. Design: Case–control study. The DQS were accessed by Dietary Habits, and Nutrition Beliefs Questionnaire (KomPAN, The Committee of Human Nutrition, Polish Academy of Science) included food frequency consumption of thirty-three food items and was formulated by six diet indexes: Pro-Healthy-Diet-Index (pHDI-10), Non-Healthy-Diet-Index (nHDI-14), High-Glycemic-Diet-Index-7 (hGIDI-7), Low-Glycemic-Diet-Index-4 (lGIDI-4), High-Sugar-Diet-Index-4 (hSDI-4) and High-Saturated-Fats-Diet-Index-8 (hSFDI-8). The BF was analysed by air displacement plethysmography (BodPod, Life Measurement Inc.). NK was assessed by using the twenty-five ‘true or false’ statements included in the KomPAN questionnaire. Setting: Poland, Clinical Hospital, Department of Endocrinology, Metabolism, and Internal Diseases. Participants: The study group included 122 PCOS women and 116 age- and socio-economic status-matched healthy controls (CON) aged 17–44 years. Results: Higher BF and lower NK in PCOS women v. controls were observed. PCOS women had a lower pHDI-10 and LGIDI-4 than CON. There was no relation between NK and DQS in PCOS women. The higher NK in the CON group was associated with increased intensity of pHDI-10 and lower frequency of hSFDI-8 levels. Conclusions: Pro-healthy DQS and NK of PCOS women in this study were lower than CON. Professional dietary education might improve dietary behaviours and understanding of the necessity of dietary habits modification in this group. A multidisciplinary approach is needed in the treatment of PCOS women.

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