scholarly journals Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations

2021 ◽  
Author(s):  
Nihal El Rouby ◽  
Mohamed H. Shahin ◽  
Loulia Bader ◽  
Sherief I. Khalifa ◽  
Hazem Elewa
Keyword(s):  
Association Analysis ◽  
Middle Eastern ◽  
Warfarin Dose ◽  
North African ◽  
African Populations ◽  
Genomewide Association

al mena: a comprehensive resource of human genetic variants integrating genomes and exomes from Arab, Middle Eastern and North African populations

2017 ◽  
Vol 62 (10) ◽  
pp. 889-894 ◽  
Author(s):  
Remya Koshy ◽  
Anop Ranawat ◽  
Vinod Scaria
Keyword(s):  
Genetic Variants ◽  
Middle Eastern ◽  
North African ◽  
African Populations

scholarly journals Review on the genetic history of Algerians within North African populations from the HLA point of view

2020 ◽  
Vol 2 (13) ◽  
pp. 140-162
Author(s):  
Abdellatif Moussouni
Keyword(s):  
North Africa ◽  
Western Europe ◽  
Middle Eastern ◽  
Point Of View ◽  
North African ◽  
Mediterranean Populations ◽  
Genetic History ◽  
African Populations ◽  
History Of ◽  
Allele Variation

This article aims to take stock of knowledge on the history of the human settlement of North Africa and the genetic history of Algerians within North African populations by gathering the most important published results related to HLA allele analysis. These results revealed a strong genetic relationship between studied North African populations (Algeria, Morocco and Tunisia). Such evident genetic affinity between North African populations, also proved by the use of other powerful autosomal markers, agrees with historic data considering North African populations as having similar origins. HLA allele analysis also indicated a genetic link between North African populations (Algeria, Tunisia and Morocco) and the populations of the South-Western Europe particularly the Basques and Spaniards. This would reflect a Neolithic relationship between Iberians and the natives of North Africa (the Berbers). However, other results showed a genetic distinction between samples from North African populations and Middle Eastern populations (Arab-Palestinians, Lebanese’s and Jordanians). Beside these results related to Mediterranean populations, the HLA allele variation was analyzed at the world scale showing low genetic differentiations among the three broad continental areas, with no special divergence of Africa. Keywords: Genetic diversity; Molecular Anthropology; Genetic History; HLA genes; North Africa; Algeria

scholarly journals Ethnic differences in out-of-hospital cardiac arrest among Middle Eastern Arabs and North African populations living in Qatar

2018 ◽  
pp. 1-10 ◽  
Author(s):  
Furqan B. Irfan ◽  
Maaret Castren ◽  
Zain A. Bhutta ◽  
Pooja George ◽  
Isma Qureshi ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Ethnic Differences ◽  
Middle Eastern ◽  
North African ◽  
African Populations ◽  
Hospital Cardiac Arrest

No Bread, No Freedom, No Social Justice

2021 ◽  
Author(s):  
Andrea Teti ◽  
Gennaro Gervasio
Keyword(s):  
Critical Discourse Analysis ◽  
Common Ground ◽  
Middle Eastern ◽  
Critical Discourse ◽  
Political Rights ◽  
The European Union ◽  
North African ◽  
Socioeconomic Rights ◽  
African Populations ◽  
The Common

Conventional approaches to democratization in the Middle East take for granted the priority of some civil–political rights (e.g., voting) over others (e.g., rights of association or protest, socioeconomic rights). The discursive structure of these approaches has framed both the promotion of democracy by the European Union and regional governments’ counter-conductive reframing against that effort. But this pas de deux is part of a broader dynamic in which the common ground shared by these two efforts frames democracy so as to deny and delegitimize both the conception of democracy held by Middle Eastern and North African populations themselves and the political and socioeconomic demands of those same populations. Governments, in short, are engaged in “counter-conducting” their own populations. Drawing on critical discourse analysis of key documents, public opinion survey data, and activist interviews, an analysis of the Egyptian case shows that the discursive competition between governments is (also) a dance around democracy which seeks to avoid the more radical, egalitarian demands by populations

Sesame allergy is more prevalent among Middle Eastern/North African patients in an urban healthcare system

2021 ◽  
Author(s):  
Christine LM. Joseph ◽  
Alexandra R. Sitarik ◽  
Rachel Kado ◽  
Gillian Bassirpour ◽  
Cheryl A. Miree ◽  
...  
Keyword(s):  
Healthcare System ◽  
Middle Eastern ◽  
North African ◽  
African Patients

scholarly journals The Assessment of COVID-19 Knowledge and Attitudes Among a Middle Eastern North African Community in Dearborn, Michigan

2021 ◽  
Author(s):  
Malak A. Ismail ◽  
Marwa Khalil ◽  
Roukaya Najdi ◽  
R. A. Blackwood
Keyword(s):  
Middle Eastern ◽  
North African ◽  
Knowledge And Attitudes ◽  
African Community

The Ideological Dimensionality in the Middle Eastern and North African Constitutions: A New Era in the Evolution of Islamic Constitutionalism

2020 ◽  
pp. 147892992091294
Author(s):  
Berna Öney
Keyword(s):  
Middle Eastern ◽  
Political Regime ◽  
North African ◽  
New Era ◽  
Regime Changes ◽  
Political Debates ◽  
Before And After ◽  
Popular Movements ◽  
Ideological Dimension

The popular movements in 2011 led to many regime changes that resulted in amended or new constitutions in the Middle East and North Africa region. The constitutional debates concentrated mainly on the functions of the constitutions in authoritarian regimes, constitution-making processes, and the role of Islam during and after the uprisings. However, no research has analyzed the ideological dimensionality of the Middle Eastern and North African constitutions. By analyzing 19 newly enacted, drafted, and amended constitutions before and after the popular movements in the region, this article shows that the single ideological dimension in the constitutions can be defined by the openness of a state for liberal and modern values. This ideological dimension encompasses all the regional political debates on the political regime dynamics, the inclusion of rights and liberties, and the role of Islam. Besides offering an alternative typology for the constitutions in the region, this article also provides evidence for the beginning of the fourth phase of Islamic constitutionalism that merges the ideas of rule of law, which originates from democratic notions, and Islamic norms.

Diversified Diasporas

1997 ◽  
Vol 6 (1) ◽  
pp. 111-122
Author(s):  
Sarah Abrevaya Stein
Keyword(s):  
Middle Eastern ◽  
North African ◽  
Joint Work ◽  
Nation States ◽  
The Many

The many contributors to this volume disagree on who, precisely, are the subjects of their joint work. Or rather, they diverge in their understanding of how their subjects should be defined, remembered, portrayed. Some of the contributors to Sephardi and Middle Eastern Jewries imagine their subjects regionally (as Middle Eastern, North African, or Balkan); others refer to them as linguistic entities (speakers of Judeo-Persian, Judeo-Spanish, or Judeo-Arabic). Others describe them as transnational or diasporic populations (Sephardi, Hispano-Jewish, or simply Jewish), while still others divide them along the borders of empires or nation-states (Ottoman, Iraqi, Moroccan, Israeli).

Clinical Profile and Health Disparities in a Multiethnic Cohort of Patients With Hypertrophic Cardiomyopathy

2021 ◽  
Vol 14 (3) ◽  
Author(s):  
Alexandra Butters ◽  
Caitlin R. Semsarian ◽  
Richard D. Bagnall ◽  
Laura Yeates ◽  
Fergus Stafford ◽  
...  
Keyword(s):  
Health Disparities ◽  
Genetic Testing ◽  
Hypertrophic Cardiomyopathy ◽  
Ethnic Groups ◽  
South Asians ◽  
Middle Eastern ◽  
East Asian ◽  
North African ◽  
East Asians ◽  
Cardioverter Defibrillator

Background: Clinical studies of hypertrophic cardiomyopathy are over-represented by individuals of European ethnicity, with less known about other ethnic groups. We investigated differences between patients in a multiethnic Australian hypertrophic cardiomyopathy population. Methods: We performed a retrospective cohort study of 836 unrelated hypertrophic cardiomyopathy probands attending a specialized clinic between 2002 and 2020. Major ethnic groups were European (n=611), East Asian (n=75), South Asian (n=58), and Middle Eastern and North African (n=68). The minor ethnicity groups were Oceanian (n=9), People of the Americas (n=7), and African (n=8). One-way ANOVA with Dunnett post hoc test and Bonferroni adjustment were performed. Results: Mean age of the major ethnic groups was 54.9±16.9 years, and 527 (65%) were male. Using the European group as the control, East Asian patients had a lower body mass index (29 versus 25 kg/m 2 , P <0.0001). South Asians had a lower prevalence of atrial fibrillation (10% versus 31%, P =0.024). East Asians were more likely to have apical hypertrophy (23% versus 6%, P <0.0001) and Middle Eastern and North African patients more likely to present with left ventricular outflow tract obstruction (46% versus 34%, P =0.0003). East Asians were less likely to undergo genetic testing (55% versus 85%, P <0.0001) or have an implantable cardioverter-defibrillator implanted (19% versus 36%, P =0.037). East Asians were more likely to have a causative variant in a gene other than MYBPC3 or MYH7 , whereas Middle Eastern and North African and South Asians had the highest rates of variants of uncertain significance (27% and 21%, P <0.0001). Conclusions: There are few clinical differences based on ethnicity, but importantly, we identify health disparities relating to access to genetic testing and implantable cardioverter-defibrillator use. Unless addressed, these gaps will likely widen as we move towards precision-medicine–based care of individuals with hypertrophic cardiomyopathy.

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