CHAPTER I: BRIEF SURVEY OF THE LITERATURE ON MORPHOLOGICAL CHANGES IN SMALL BLOOD VESSELS IN PATIENTS WITH DIABETES MELLITUS

2009 ◽  
Vol 183 (S480) ◽  
pp. 7-17
Keyword(s):  
Diabetes Mellitus ◽  
Blood Vessels ◽  
Morphological Changes ◽  
Patients With Diabetes

scholarly journals Monitoring of Patient With Diabetes Mellitus

2017 ◽  
Vol 3 (2) ◽  
pp. 55
Author(s):  
Widodo Widodo
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Blood Vessels ◽  
Insulin Action ◽  
Laboratory Tests ◽  
Impaired Insulin Secretion ◽  
Chronic Hyperglycemia ◽  
Impaired Insulin ◽  
Patients With Diabetes ◽  
Impaired Insulin Action

Diabetes mellitus is a disease characterized by hyperglycemia, which is caused by impaired insulin secretion, impaired insulin action, or both. Chronic hyperglycemia will lead to dysfunction and damage to various organs, such as the eyes, kidneys, nerves, heart, and blood vessels. This paper discusses the monitoring of patients with diabetes mellitus according to the laboratory tests, to know when the results of therapy has reached the optimum point as well as the prevention of complications that can occur.  

scholarly journals INCREASING FOOT CIRCULATION WITH ELECTRICAL STIMULATION IN PATIENTS WITH DIABETES MELLITUS

2018 ◽  
Vol 4 (3) ◽  
pp. 343-349
Author(s):  
Iskandar Iskandar ◽  
Ridha Dharmajaya ◽  
Yesi Ariani
Keyword(s):  
Diabetes Mellitus ◽  
Blood Flow ◽  
Electrical Stimulation ◽  
Blood Vessels ◽  
Diabetic Foot ◽  
Ankle Brachial Index ◽  
Sampling Technique ◽  
Calf Muscle ◽  
Patients With Diabetes ◽  
Peripheral Arterial

Background: Peripheral arterial disorders in diabetes mellitus is a common complication that often occurs and can develop into diabetic foot ulcers. High blood sugar levels in people with diabetes mellitus can cause increased blood viscosity resulting in thickening of the capillary membrane, where erythrocytes, platelets and leucocytes are attached to the blood vessels. Electrical stimulation by placing electrodes in the calf muscle is one of the measures to increase foot blood flow that can reduce the poor foot circulation.Objective: This study aims to determine the effect of electrical stimulation in improving blood flow of patients with diabetes mellitus.Methods: The research use one-group pretest-posttest pre-experimental design. Sampling technique using pusposive sampling as many as 62 patients with diabetes mellitus. Electrical stimulation is done by attaching electrodes to left and right calf muscles for 20 minutes, frequency 3 times a week for 2 weeks. Before and after electrical stimulation performed foot circulation examination by ankle brachial index technique. Data analysis using Wilcoxon signed rank test.Results: The results showed that before the stimulation was obtained the mean ankle brakhial index 0.82 mmHg and after stimulation 0.95 mmHg (p = 0.000), meaning there is an effect of electrical stimulation in increasing foot blood flow. A calf muscle contraction during stimulation leads to increased leg blood flow through the addition of vascular endothelial growth factor and increased nitric oxide as a vasodilator of blood vessels. Electrical stimulation can be applied in increasing the blood flow of the foot, thus preventing the occurrence of diabetic foot ulcers.Conclusion: Stimulation is one therapy that can be done to prevent poor foot circulation of diabetes mellitus patients. 

Abstract 12226: Left Atrial Structure and Function and Cardiovascular Events in Patients With Diabetes Mellitus: Results From Multi-Ethnic Study of Atherosclerosis (MESA)

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Timothy M Markman ◽  
Mohammadali Habibi ◽  
Bharath Ambale-Venkatesh ◽  
Mytra Zareian ◽  
Colin Wu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cox Regression ◽  
Morphological Changes ◽  
Population Based ◽  
Structure And Function ◽  
Volume Index ◽  
Kaplan Meier ◽  
Patients With Diabetes ◽  
Asymptomatic Individuals ◽  
And Function

Introduction: Diabetes mellitus (DM) is associated with the development of cardiovascular disease (CVD). Morphological changes in the LA may appear before symptoms. We aimed to investigate the association between cardiac magnetic resonance imaging (CMR) measured LA structure and function and incident CVD in asymptomatic individuals with DM. Methods: Tissue tracking CMR was used to measure LA size and phasic emptying fraction (EF) on all 574 MESA participants with DM and available baseline CMR, which was performed between 2000 and 2002. MESA is a population based, multi-center cohort study of 6814 healthy individuals. CVD was defined as MI, resuscitated cardiac arrest, angina, stroke, heart failure, atrial fibrillation, and any mortality secondary to CVD. Cox regression was used to assess the association of LA parameters with incident CVD adjusted for traditional risk factors, LV mass assessed by CMR, NT Pro-BNP and maximum LA volume. Adjusted Kaplan-Meier curves are based on 25th percentile cut-offs. Results: After a mean follow up of 7 years, 96 individuals developed CVD (mean age 64, 53%male, 79% treated). Individuals with incident CVD (mean age 66 years, 66% male vs. mean age 4 years, 50% male) had larger maximum and minimum LA volume index (LAVI) (32±13 mm3/m2 vs. 27±10 mm3/m2; 20±10mm3/m2 vs. 14 ±6 mm3/m2), and lower total and active EF than those without CVD (42±11% vs. 48±9%; 29±11% vs. 32±11%). p<0.01 for all. In the final model, there was a significant association of minimum LAVI, LA total EF, and LA active EF with incident CVD. Conclusions: CMR measured LA structure and function are predictive of CVD in a diabetic multi-ethnic population free of any symptomatic CVD at baseline.

Liver damage in patients with diabetes mellitus in the practice of a family doctor

2021 ◽  
pp. 31-39
Author(s):  
Vsevolod Vladimirovich Skvortsov Vsevolod Vladimirovich Skvortsov ◽  
Arina Nikolaevna Gorbach ◽  
Aleksandr Vladimirovich Tumarenko ◽  
Daniil Alekseevich Shtonda ◽  
Vera Andreevna Chuvileva ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Morphological Changes ◽  
Family Doctor ◽  
Liver Parenchyma ◽  
Fatty Degeneration ◽  
Alcoholic Fatty Liver ◽  
Patients With Diabetes

This article presents information on the main pathological processes developing in the liver in diabetes mellitus. Non-alcoholic fatty liver disease (NAFLD) is an independent nosological unit that includes a spectrum of clinical and morphological changes in the liver parenchyma: steatosis (fatty degeneration) and non-alcoholic steatohepatitis (NASH), the natural course of which can lead to the development of terminal stages of the disease: cirrhosis and liver cancer. This article is devoted to the etiology, pathogenesis, clinical picture, diagnosis and treatment of fatty liver disease in patients with diabetes mellitus.

scholarly journals Diabetes Melitus dan Antioksidan

2019 ◽  
Vol 1 (1) ◽  
pp. 48-52
Author(s):  
Dita Sukmaya Prawitasari
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Free Radicals ◽  
Blood Vessels ◽  
Microvascular Dysfunction ◽  
Mortality Rates ◽  
Pathological Process ◽  
The World ◽  
Patients With Diabetes ◽  
Diabetes Melitus

Abstract — Diabetes mellitus is widely known as one of the non-transmittable diseases which is a global problem because its incidence is increasing every year throughout the world. The condition of hyperglycemia in diabetes mellitus has a very influential effect on endothelial blood vessels due to the process of glucose auto-oxidation in forming free radicals which in turn will produce macro and microvascular dysfunction. Next, this condition will further increase morbidity and mortality rates in people with diabetes mellitus. The using of antioxidants in patients with diabetes mellitus was found to be effective in reducing the emergence of arising complications. This is supported by various the benefits of antioxidants related to pathological process of diabetes mellitus due to conditions of oxidative stress. In the future, the safety and effectiveness of supplements or food contain antioxidants in an effort to overcome the condition of diabetes must still be proven further. Abstrak— Diabetes melitus banyak dikenal sebagai salah satu penyakit tidak menular yang menjadi masalah global karena insidensinya setiap tahun yang terus meningkat di seluruh dunia. Kondisi hiperglikemia pada diabetes melitus mempunyai efek yang sangat berpengaruh pada endotel pembuluh darah akibat adanya proses auto-oksidasi glukosa dalam membentuk radikal bebas yang pada akhirnya akan menghasilkan disfungsi makro dan mikrovaskular. Kondisi inilah yang selanjutnya akan menimbulkan komplikasi yang selanjutnya akan meningkatkan angka morbiditas maupun mortalitas pada penderita diabetes melitus. Penggunaan antioksidan pada penderita diabetes melitus ternyata diketahui efektif dalam mengurangi munculnya komplikasi yang timbul. Hal ini didukung dengan berbagai penelitian yang membuktikan manfaat antioksidan terkait proses patologi dari diabetes mellitus akibat kondisi stres oksidatif. Pada masa yang akan datang, keamanan dan keefektifan suplemen atau makanan yang mengandung antioksidan dalam upaya mengatasi kondisi diabetes tetap harus dibuktikan lebih lanjut.

scholarly journals Cornea and its changes in diabetes mellitus: the review

2016 ◽  
Vol 19 (6) ◽  
pp. 479-485 ◽  
Author(s):  
Mukharram M. Bikbov ◽  
Valentina K. Surkova
Keyword(s):  
Diabetes Mellitus ◽  
Morphological Changes ◽  
Disease Diagnosis ◽  
Original Research ◽  
Nerve Fibres ◽  
Corneal Disease ◽  
Endocrine Disease ◽  
Ocular Manifestations ◽  
Modern Methods ◽  
Patients With Diabetes

Diabetes mellitus (DM) is the most common endocrine disease, which makes it a priority among health and social problems. Ocular manifestations in diabetes often lead to patient disability. This review presents an analysis of morphological, experimental and clinical studies of the cornea in patients with diabetes mellitus, including original research, reviews and monographs of Russian and foreign authors from recent years. In addition, modern methods of corneal disease diagnosis are reviewed. Clinical and morphological changes in the diabetic cornea are discussed and early diabetic changes in all structural layers are indicated. The importance of changes to nerve fibres in diabetes is discussed and the correlation between the density of nerve fibres in the cornea and the density of epidermal nerve fibres is shown.

Intramuscular Nerve and Neuromuscular Junction Alteration In Extraocular Muscles of Diabetic Mice

1985 ◽  
Vol 43 ◽  
pp. 682-683
Author(s):  
Bruce R. Pachter
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Nerves ◽  
Sudden Onset ◽  
Extraocular Muscles ◽  
Diabetic Patients ◽  
Oculomotor Palsy ◽  
Third Nerve Palsy ◽  
Patients With Diabetes ◽  
Intramuscular Nerve ◽  
Oculomotor Nerves

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).

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