Direct and indirect effects of solar ultraviolet-B radiation on long-term decomposition

2005 ◽  
Vol 0 (0) ◽  
pp. 051006062331002-??? ◽  
Author(s):  
Veronica A. Pancotto ◽  
Osvaldo E. Sala ◽  
T. Matthew Robson ◽  
Martyn M. Caldwell ◽  
Ana L. Scopel
2021 ◽  
pp. oemed-2020-107125
Author(s):  
Julie Elbaek Pedersen ◽  
Katrine Strandberg-Larsen ◽  
Michael Andersson ◽  
Johnni Hansen

ObjectivesPrevious epidemiological studies have indicated that solar ultraviolet B radiation (UVR) may have a protective effect on breast cancer. However, the evidence remains inconclusive. Despite the fact that outdoor work history may be considered a reliable measure of long-term UVR exposure, objective information on lifetime employment has not been included in previous investigations focusing on breast cancer. To address this issue, we explored the association between occupational UVR exposure and female breast cancer, including subtypes.MethodsA total of 38 375 women under the age of 70 years were identified with primary breast cancer using the Danish Cancer Registry. Five female controls born on the same year, alive and free of breast cancer at the time of diagnosis of the index case, were randomly selected from the Danish Civil Registration System. The Danish Supplementary Pension Fund Register was used to retrieve full employment history, and a job exposure matrix was used to assess occupational UVR exposure. Conditional logistic regression with adjustment for important confounders was used to estimate the OR.ResultsWe observed no overall association between occupational UVR exposure and breast cancer. After the age of 50 years, longer duration of UVR exposure (≥20 years: OR=0.83, 95% CI 0.75 to 0.92) and highest cumulative exposure (OR=0.89, 95% CI 0.83 to 0.95) were inversely associated with risk. Our results did not reflect any notable risk difference by oestrogen receptor status.ConclusionsThis study indicates an inverse association between long-term occupational UVR exposure and late-onset breast cancer. This finding needs further attention in future occupational studies.


2019 ◽  
Vol 135 ◽  
pp. 287-294 ◽  
Author(s):  
Carlos Marfil ◽  
Verónica Ibañez ◽  
Rodrigo Alonso ◽  
Anabella Varela ◽  
Rubén Bottini ◽  
...  

Author(s):  
Charles Alessi ◽  
Larry W. Chambers ◽  
Muir Gray

This chapter starts by advising how to reduce the impact of stress. When stress becomes long term, the immune system becomes less sensitive to cortisol, and since inflammation is partly regulated by this hormone, this decreased sensitivity heightens the inflammatory response and allows inflammation to get out of control, increasing our risk of many diseases. You can reduce your stress yourself through a variety of methods, including physical activity and mindfulness-based stress reduction. Adequate sleep is also a major factor that can improve cognitive abilities and reduce the risk of dementia, and this chapter outlines what we need to know about sleep cycles, insomnia, and sleep disordered breathing, and how to sleep more and sleep better. The chapter then covers how to protect your brain from over medication (polypharmacy). It finishes by discussing how to maintain and indeed increase your levels of physical activity, and how increasing physical activity has both direct and indirect effects on the brain.


2020 ◽  
Vol 12 (17) ◽  
pp. 6811
Author(s):  
Ramon Mahia ◽  
Rafael de Arce

The aim of this article is to simulate the economic impact on Gross Domestic Product (GDP) and employment of renewable energy sources investment in Morocco over the next 40 years. In this sense, several potential scenarios of energy component evolution have been used based on the results of a specific survey to sector stakeholders. We obtain accurate results, avoiding speculative/theoretical assumptions in terms of scenario design. As usual in the sector, a Dynamic Input–Output Model (DI–O) is used to estimate the direct and indirect effects of such a large investment and, avoiding the criticism of this type of model in the context of long-term simulations, the alternative of de Arce et al. (2012) is used. In this framework, substantial results derive from the three scenarios considered: the increase in Moroccan GDP as a result of this investment could be around 1.2–1.7 points and, on average, 42,000 new jobs could be created.


2017 ◽  
Vol 2017 ◽  
pp. 1-11
Author(s):  
Seyed Aidin Sajedi ◽  
Fahimeh Abdollahi

Background. Insufficient received ultraviolet B radiation (UV) is regarded as the main environmental risk factor (RF) for MS in vitamin D deficiency hypothesis. Nevertheless, geomagnetic disturbance (GMD) has also been proposed as a potential trigger for MS in GMD hypothesis. The aim of this study was to investigate which of these mentioned RF is correlated with long-term ultradecadal MS incidence. Methods. After a systematic search, long-term incidence reports of the United Kingdom (UK), Denmark, Tayside County, Nordland County, the Orkney, and Shetland Islands were selected for this retrospective time-series study. Possible lead-lag relationships between MS incidence, GMD, and UV were evaluated by cross-correlation analysis. Results. Significant positive correlations between GMD and MS incidence were seen in Tayside County (at lag of 2 years: rS = 0.38), Denmark (peak correlation at lag of 2 years: rS = 0.53), and UK (at lag of 1 year: rS = 0.50). We found a positive correlation between received UV and MS incidences in the Nordland at lag of 1 year (rS = 0.49). Conclusion. This study found significant positive correlations between alterations in GMD with alterations in long-term MS incidence in three out of six studied locations and supports the GMD hypothesis. The observed significant correlation between MS and UV is positive; hence it is not supportive for UV related vitamin D deficiency hypothesis.


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