Parental diabetes, pubertal stage, and extreme obesity are the main risk factors for prediabetes in children and adolescents: a simple risk score to identify children at risk for prediabetes

2009 ◽  
Vol 10 (6) ◽  
pp. 395-400 ◽  
Author(s):  
Thomas Reinehr ◽  
Martin Wabitsch ◽  
Michaela Kleber ◽  
Gideon de Sousa ◽  
Christian Denzer ◽  
...  
2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Susanna Esposito ◽  
Fabio Caramelli ◽  
Nicola Principi

Abstract Background Although with exceptions, evidence seems to indicate that children have lower susceptibility than adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. When infected, children generally remain asymptomatic or develop mild disease. A small number of pediatric cases required admission to the pediatric intensive care unit (PICU), respiratory support with a mechanical ventilation and additional life-saving interventions. Even if rarely, death can occur. Aim of this manuscript is to highlight the risk factors associated with severe outcome among pediatric patients with COVID-19. Main findings Early identification of SARS-CoV-2-infected children at risk of developing severe COVID-19 is vital for service planning, as severely affected pediatric patients require high-quality care and should be followed only where an adequately structured PICU is available. However, early identification of children who must be carefully monitored for substantial risk of severe COVID-19 remains difficult. An underlying comorbidity and heart involvement are frequently observed in severe paediatric cases. Reduced left ventricular systolic function with an ejection fraction < 60%; diastolic dysfunction; and arrhythmias, including ST segment changes, QTc prolongation, and premature atrial or ventricular beat, are the earliest manifestations of heart involvement. Inclusion of heart enzyme serum levels and evaluation of ventricular function among predictive markers could lead to a more effective evaluation of children at risk with proper selection of those to admit to the PICU and with more adequate treatment in case of more severe clinical manifestations. Conclusions To appropriately manage severe pediatric COVID-19 cases, greater attention should be paid to risk factors in children and adolescents, especially to cardiovascular alterations (e.g., heart enzyme serum levels and evaluation of ventricular function). Further studies are needed and the development of a validated score based on all the most common presumed markers of disease severity seems essential.


2000 ◽  
Vol 72 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Isabelle Sermet-Gaudelus ◽  
Anne-Sylvie Poisson-Salomon ◽  
Virginie Colomb ◽  
Marie-Claire Brusset ◽  
Françoise Mosser ◽  
...  

1996 ◽  
Vol 17 (3) ◽  
pp. 94-97
Author(s):  
Thomas J. Starc ◽  
Richard J. Deckelbaum

For many adults, the risk of atherosclerosis can be reduced by intervention and treatment of known risk factors. Direct proof that similar intervention will be effective in children is not available. However, evidence suggests that prevention beginning in childhood will lead to a decrease in incidence of heart disease later in life. The majority of families are eager to take steps to prevent heart disease in their children, especially if there is a family history of early heart disease. It is the role of the pediatrician to identify those children at risk for early heart disease and to initiate advice on reducing risk factors.


2007 ◽  
Vol 73 (3) ◽  
pp. 367-379 ◽  
Author(s):  
J. Ron Nelson ◽  
Scott Stage ◽  
Kristin Duppong-Hurley ◽  
Lori Synhorst ◽  
Michael H. Epstein

Author(s):  
Rahul Baijal ◽  
Carlos J. Campos

Management of the pediatric surgical patient in diabetic ketoacidosis (DKA) is particularly challenging given the electrolyte and acid-base abnormalities, compounded with the risk of cerebral edema. This chapter highlights the risk factors, diagnosis, and treatment plan, for the pediatric surgical patient who presents in DKA. This chapter will help the reader identify children at risk for DKA, understand the clinical presentation and pathophysiology of DKA, identify children at risk for cerebral edema, manage cerebral edema in children with DKA, manage DKA in children, and understand the anesthetic implications in children with DKA.


2008 ◽  
Vol 33 (2) ◽  
pp. 75-86 ◽  
Author(s):  
J. Ron Nelson ◽  
Scott Stage ◽  
Alex Trout ◽  
Kristin Duppong-Hurley ◽  
Michael H. Epstein

PEDIATRICS ◽  
1980 ◽  
Vol 66 (6) ◽  
pp. 834-837
Author(s):  
Charles J. Glueck

Can we detect children at risk for coronary disease? Focusing upon screening for hyperlipidemia in childhood, Holtzman1 recently concluded "...at this juncture we do not know how to detect most children at risk for coronary disease, and even if we did, we would not know what to do when we found them." Holtzman's conclusions, however, seem to be incongruent with multiple, extensive, population-based studies of coronary heart disese (CHD) risk factors in children. One hundred twenty-nine years ago, Semmelweis2 summarized his data relative to etiologies of puerperal fever, and suggested preventive medical approaches, much to the derision of his contemporaries.


Author(s):  
Canan Yildiz Çiçekler ◽  
Devlet Alakoç Pirpir

Children's exposure to many risk factors such as; need for protection, living on the streets, working, abuse and neglected, pushed into crime, exposed to violence, obliged to immigrate due to war, living under socio-economic disadvantageous conditions, having chronic diseases, being a disabled child and living in divorced families can arise from both their families and from the social structure. Throughout the world, many children live at risk due to various reasons. Irrespective of the reasons, which risk group the children enter and the factors causing this situation should be examined. According to the obtained data, the factors causing to such situations should be determined and necessary precautions should be taken. Thus, the negative conditions, under which the children are, can be improved and the children can be reintegrated into society.


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