Comparison of the bacterial isolates and antibiotic resistance patterns of elderly nursing home and general community patients

2012 ◽  
Vol 42 (7) ◽  
pp. e157-e164 ◽  
Author(s):  
C. Xie ◽  
D. McD. Taylor ◽  
B. P. Howden ◽  
P. G. P. Charles
Keyword(s):  
Antibiotic Resistance ◽  
Nursing Home ◽  
Bacterial Isolates ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns ◽  
General Community ◽  
Community Patients

scholarly journals BACTERIAL CONJUNCTIVITIS OF ADULTS: CAUSES AND OPHTHALMIC ANTIBIOTIC RESISTANCE PATTERNS FOR THE COMMON BACTERIAL ISOLATES

2021 ◽  
Author(s):  
Sameha A. Al-Eryani ◽  
Essam Yahya A Alshamahi ◽  
Hassan A. Al-Shamahy ◽  
Ghada Hussein A Alfalahi ◽  
Abdulrahman Ahmed Al-Rafiq
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Peer Review ◽  
Age Groups ◽  
Polymyxin B ◽  
Adult Patients ◽  
Bacterial Isolates ◽  
Bacterial Conjunctivitis ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

Background: Bacterial conjunctivitis is often observed in newborns as well as in other age groups. It has been associated with several organisms that differed in their relative importance and varied in their response to ophthalmic antibiotics. Objectives: The aim of this study was to investigate bacterial conjunctivitis of adult patients by determine the specific bacterial causes and determine the  ophthalmic antibiotic resistance patterns for the bacterial isolates from conjunctivitis patients in Sana’a city, Yemen.  Methods: Total 521 bacterial swabs obtained from adult patients with suspected bacterial conjunctivitis introducing to the ophthalmology clinics in the tertiary hospitals in Sana’a city, Yemen between September 2016 and October 2017 were investigated for bacteriological agents and antibiotic susceptibility . The clinical samples culturing, and microbiology diagnosis were done at National Center of Public Health laboratories Sana’a (NCPHL).  Result: Total 521 swab results from conjunctiva were performed, of which 206 (39.5%) were deemed positive for bacterial culture. The isolation rate by bacteria species ranged from 0.5% to 28.2%. In Staphylococcus aureus isolates, ophthalmic antibiotic resistance varied from 10.5% for polymyxin B to 66.7% for erythromycin. In Branhamella catarrahalis isolates, ophthalmic antibiotic resistance ranged from 3.4% for levofloxacin to 69% for erythromycin. In Haemophilus influenzae isolates, ophthalmic antibiotic resistance varied from 0.0% for ciprofloxacin and polymyxin B to 42.1% for erythromycin and azithromycin. Conclusion: The most common causative organisms in adult age groups were Branhamella catarrahalis and Staphylococcus aureus. Obviously, there is no single drug that treats these various types of bacteria. Therefore, bacteriological culture and sensitivity in the laboratory to ophthalmic antibiotics should be performed as much as possible. But if laboratory facilities are not available, some generalizations can be made as guidelines for treating conjunctivitis.                     Peer Review History: Received 6 January 2021; Revised 15 February; Accepted 4 March, Available online 15 March 2021 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Bilge Ahsen KARA, Ankara Gazi Mustafa Kemal Hospital, Turkey, [email protected] Dr. Gulam Mohammed Husain, National Research Institute of Unani Medicine for Skin Disorders, Hyderabad, India, [email protected] Dr. Mujde Eryilmaz, Ankara University,Turkey, [email protected]   Similar Articles: BACTERIAL CAUSES AND ANTIMICROBIAL SENSITIVITY PATTERN OF EXTERNAL OCULAR INFECTIONS IN SELECTED OPHTHALMOLOGY CLINICS IN SANA’A CITY

scholarly journals Antibiotic resistance in patients with chronic ear discharge awaiting surgery in Nepal

2021 ◽  
Vol 11 (1) ◽  
pp. 1-5
Author(s):  
R. R. Karn ◽  
R. Acharya ◽  
A. K. Rajbanshi ◽  
S. K. Singh ◽  
S. K. Thakur ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Multidrug Resistant ◽  
Bacterial Isolates ◽  
Hospital Data ◽  
Ear Surgery ◽  
Suppurative Otitis Media ◽  
Cross Border ◽  
Cortical Mastoidectomy ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

SETTING: Biratnagar Eye Hospital, Biratnagar, Nepal, which offers ear surgery for chronic suppurative otitis media (CSOM).OBJECTIVE: In patients with CSOM awaiting surgery, to determine the 1) sociodemographic characteristics 2) bacterial isolates and their antibiotic resistance patterns and 3) characteristics of those refused surgery, including antibiotic resistance.DESIGN: A cohort study using hospital data, January 2018–January 2020.RESULTS: Of 117 patients with CSOM and awaiting surgery, 64% were in the 18–35 years age group, and 79% were cross-border from India. Of 118 bacterial isolates, 80% had Pseudomonas aeruginosa and 16% had Staphylococcus aureus. All isolates showed multidrug resistance to nine of the 12 antibiotics tested. The lowest antibiotic resistance in P. aeruginosa was for vancomycin (29%) and moxifloxacin (36%), and for S. aureus, this was vancomycin (9%) and amikacin (17%). Fourteen (12%) patients underwent surgery: myringoplasty (n = 7, 50%), cortical mastoidectomy with tympanostomy (n = 4, 29%) and modified radical mastoidectomy (n = 3, 21%). Those infected with P. aeruginosa and with resistance to over six antibiotics were significantly more likely to be refused for surgery.CONCLUSION: Patients awaiting ear surgery were predominantly infected with multidrug-resistant P. aeruginosa and were consequently refused surgery. This study can help inform efforts for improving surgical uptake and introducing cross-border antimicrobial resistance surveillance.

scholarly journals Antibiotic resistance patterns of bacterial isolates from hatcheries and selected fish farms in the Ashanti region of Ghana

2017 ◽  
Vol 9 (4) ◽  
pp. 35-46 ◽  
Author(s):  
Eyram Agoba Esther ◽  
Adu Francis ◽  
Agyare Christian ◽  
Etsiapa Boamah Vivian ◽  
Duah Boakye Yaw
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Isolates ◽  
Fish Farms ◽  
Ashanti Region ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

scholarly journals Antibiotic resistance patterns of bacteria isolated from indwelling Foley catheters following tube cystostomy in goats with obstructive urolithiasis

2017 ◽  
Vol 29 (3) ◽  
pp. 316-320 ◽  
Author(s):  
Munashe Chigerwe ◽  
Vengai Mavangira ◽  
Barbara A. Byrne ◽  
John A. Angelos
Keyword(s):  
Antibiotic Resistance ◽  
Susceptibility Testing ◽  
Bacterial Isolate ◽  
Foley Catheter ◽  
Urine Samples ◽  
Bacterial Isolates ◽  
Testing Resistance ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns ◽  
Susceptibility Patterns

Tube cystostomy is a surgical method used for managing obstructive urolithiasis and involves placement of a Foley catheter into the urinary bladder. We identified and evaluated the antibiotic resistance patterns of bacteria isolated from indwelling Foley catheters following tube cystostomy in goats with obstructive urolithiasis. Urine samples collected over a 10-y period from catheter tips at the time of removal were submitted for bacteriologic culture and antibiotic susceptibility testing. Resistance patterns to antibiotics, trends in the resistance patterns over the study period, and the probability of a bacterial isolate being resistant as a function of the identity of the isolate and antibiotic tested were determined. A total of 103 urine samples from 103 male goats with obstructive urolithiasis managed surgically with tube cystostomy were included in the study. Aerococcus (36.9%) and Enterococcus (30.1%) were isolated most frequently. The susceptibility patterns of all bacteria isolated did not change over the study period ( p > 0.05). Proportions of isolates resistant to 1, 2, and ≥3 antibiotics were 36.9%, 18.5%, and 23.3%, respectively. Thus, 41.8% of bacterial isolates were resistant to 2 or more antibiotics tested. The probability of Aerococcus spp., Escherichia coli, and Pseudomonas aeruginosa isolates to be resistant to ampicillin, ceftiofur, erythromycin, penicillin, or tetracycline ranged from 0.59 to 0.76.

scholarly journals Evaluation of antibiotic resistance patterns and heavy metals tolerance of some bacteria isolated from contaminated soils and sediments from Warri, Delta State, Nigeria

2016 ◽  
Vol 20 (2) ◽  
pp. 287-291
Author(s):  
A.F. Eghomwanre ◽  
N.O. Obayagbona ◽  
O Osarenotor ◽  
B.J. Enagbonma
Keyword(s):  
Heavy Metals ◽  
Antibiotic Resistance ◽  
Contaminated Soils ◽  
River Sediments ◽  
Spare Parts ◽  
Diffusion Method ◽  
Bacterial Isolates ◽  
Soils And Sediments ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

This work investigated the antibiotic resistance patterns and heavy metals such as Lead (Pb), Zinc (Zn), Cadmium (Cd) and iron (Fe) tolerance of selected bacteria isolated from contaminated soils and sediments around Warri area of Delta State. The heterotrophic bacterial counts for the sampled soils and sediments ranged from 1.7×105 cfu/g to 5.7×105cfu/g for Ubeji river sediments, 1.0×105 cfu/g to 9.0×105cfu/g for spare parts dumpsite and 1.2×104cfu/g to 9.0×104 cfu/g for Ifie depot sites respectively. The characterized bacterial isolates included; Klebsiella sp, Bacillus subtilis, Streptococcus sp., Escherichia coli, Klebsiella mobilis and Staphylococcus sp., Micrococcus sp. and Pseudomonas aeroginosa. Bacterial isolates showed multiple drug resistance and the most resistant isolates were S. aureus, E. coli and P. aeroginosa while K. mobilis exhibited the least resistance. The tolerance of the bacterial isolates exposed to varying concentrations of Pb2+, Cd2+, Fe2+, and Zn2+was ascertained using agar diffusion method. All the bacterial isolates exhibited varying degree of susceptibility at different concentrations of Pb and Cd while the organisms displayed abundant and moderate growth in the presence of Fe and Zn even at higher concentrations. The ability of these bacteria to resist antibiotics and heavy metal tolerance could present serious danger to the environment as the resistance genes may be transferred to surrounding wild type microbial cells.Keywords: Heavy metals, Antibiotics resistance, tolerance, Ubeji river sediments, Warri

scholarly journals Antibiotic Resistance Patterns of Bacterial Isolates from Neonatal Sepsis Patients at University Hospital of Leipzig, Germany

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 323
Author(s):  
Belay Tessema ◽  
Norman Lippmann ◽  
Matthias Knüpfer ◽  
Ulrich Sack ◽  
Brigitte König
Keyword(s):  
Antibiotic Resistance ◽  
Neonatal Sepsis ◽  
University Hospital ◽  
Resistant Bacteria ◽  
Bacterial Isolates ◽  
Gram Positive ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

Neonatal sepsis caused by resistant bacteria is a worldwide concern due to the associated high mortality and increased hospitals costs. Bacterial pathogens causing neonatal sepsis and their antibiotic resistance patterns vary among hospital settings and at different points in time. This study aimed to determine the antibiotic resistance patterns of pathogens causing neonatal sepsis and to assess trends in antibiotic resistance. The study was conducted among neonates with culture proven sepsis at the University Hospital of Leipzig between November 2012 and September 2020. Blood culture was performed by BacT/ALERT 3D system. Antimicrobial susceptibility testing was done with broth microdilution method based on ISO 20776-1 guideline. Data were analyzed by SPSS version 20 software. From 134 isolates, 99 (74%) were gram positive bacteria. The most common gram positive and gram negative bacteria were S. epidermidis, 51 (38%) and E. coli, 23 (17%), respectively. S. epidermidis showed the highest resistance to penicillin G and roxithromycin (90% each) followed by cefotaxime, cefuroxime, imipenem, oxacillin, and piperacillin-tazobactam (88% each), ampicillin-sulbactam (87%), meropenem (86%), and gentamicin (59%). Moreover, S. epidermidis showed raising levels of resistance to amikacin, gentamicin, ciprofloxacin, levofloxacin, moxifloxacin, and cotrimoxazol. Gram positive bacteria showed less or no resistance to daptomycin, linezolid, teicoplanin, and vancomycin. E. coli showed the highest resistance to ampicillin (74%) followed by ampicillin-sulbactam (52%) and piperacillin (48%). Furthermore, increasing levels in resistance to ampicillin, ampicillin-sulbactam, piperacillin, and cefuroxime were observed over the years. Encouragingly, E. coli showed significantly declining trends of resistance to ciprofloxacin and levofloxacin, and no resistance to amikacin, colistin, fosfomycin, gentamicin, imipenem, piperacillin-tazobactam, and tobramycin. In conclusion, this study demonstrates that gram positive bacteria were the leading causes of neonatal sepsis. Bacterial isolates were highly resistant to first and second-line empiric antibiotics used in this hospital. The high levels of antibiotic resistance patterns highlight the need for modifying empiric treatment regimens considering the most effective antibiotics. Periodic surveillance in hospital settings to monitor changes in pathogens, and antibiotic resistance patterns is crucial in order to implement optimal prevention and treatment strategies.

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