Natural history of primary precursor B lymphoblastic lymphoma of the ovary: Report of a rare case

2012 ◽  
Vol 39 (2) ◽  
pp. 611-616 ◽  
Author(s):  
Rajni Yadav ◽  
Mehar Chand Sharma ◽  
Asis Kumar Karak ◽  
Nutan Agarwal ◽  
Rajive Kumar ◽  
...  
Blood ◽  
1961 ◽  
Vol 17 (5) ◽  
pp. 597-609 ◽  
Author(s):  
PRAWASE WASI ◽  
MATTHEW BLOCK

Abstract The following conclusions can be made concerning the cause of anemia in patients with untreated chronic lymphatic leukemia excluding the rare case with an autoimmune hemolytic anemia: 1. Early in the natural history of the disease there is a normal amount of erythroblastic tissue which produces red cells at a normal rate. The rate of red cell destruction is also normal. 2. With progression of the disease the erythroblastic tissue is gradually replaced by lymphatic tissue, leading to a decrease in red cell production. The rate of red cell destruction is still normal. 3. Only late in the disease may decreased rate of red cell production be aggravated by an increased rate of red cell destruction.


2018 ◽  
Vol 63 (No. 1) ◽  
pp. 40-49
Author(s):  
P. Borska ◽  
R. Husnik ◽  
P. Fictum ◽  
A. Kehl ◽  
L. Leva ◽  
...  

A four-year-old Bullmastiff weighing 44 kg was presented with a 14-day history of weight loss, vomiting and diarrhoea. Abdominal ultrasonography showed the presence of abdominal lymphadenopathy and thickening of the wall of the descending colon. Esophagogastroduodenoscopy and colonoscopy with biopsy were performed. Histological examination revealed a high-grade lymphoblastic lymphoma, flow cytometric analysis detected malignant cells of the immature B phenotype. PCR for antigen receptor rearrangement confirmed IgH monoclonality pointing together with immunophenotyping to B-cell lymphoma. The dog was treated using a multi-agent chemotherapy protocol. The overall survival time was 487 days. This was an unusual case of primary gastrointestinal B-lymphoblastic lymphoma in a dog with survival equivalent to that of the multicentric form.


2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Rute Alves ◽  
Margarida França

Infection by Treponema pallidum still represents a clinical challenge due to its various forms of presentation. HIV coinfection added diversity and changed the natural history of syphilis as a systemic infection. We present a rare case of subacute hypophysitis and panhypopituitarism due to an early active neurosyphilis in a previously unknown HIV coinfected patient.


BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e027204
Author(s):  
Nadia Amin ◽  
Sally Kinsey ◽  
Richard Feltbower ◽  
Jeannette Kraft ◽  
Elizabeth Whitehead ◽  
...  

IntroductionOsteonecrosis is a well-recognised treatment-related morbidity risk in patients diagnosed with acute lymphoblastic leukaemia (ALL) and lymphoblastic lymphoma (LBL), with a high rate of affected patients requiring surgical intervention. Patients may have asymptomatic changes on imaging studies that spontaneously regress, and little is known about the natural history of osteonecrotic changes seen. The main aim of the British OsteoNEcrosis Study (BONES) is to determine the incidence of symptomatic and asymptomatic osteonecrosis in the lower extremities of survivors of ALL or LBL diagnosed aged 10–24 years in the UK at different time points in their treatment. This study also aims to identify risk factors for progression and the development of symptomatic osteonecrosis in this population, as well as specific radiological features that predict for progression or regression in those with asymptomatic osteonecrosisMethods and analysisBONES is a prospective, longitudinal cohort study based at principal treatment centres around the UK. Participants are patients aged 10–24 years diagnosed with ALL or LBL under standard criteria. Assessment for osteonecrosis will be within 4 weeks of diagnosis, at the end of delayed intensification and 1, 2 and 3 years after the start of maintenance therapy. Assessment will consist of MRI scans of the lower limbs and physiotherapy assessment. Clinical and biochemical data will be collected at each of the time points. Bone mineral density data and vertebral fracture assessment using dual-energy X-ray absorptiometry will be collected at diagnosis and annually for 3 years after diagnosis of malignancy.Ethics and disseminationEthical approval has been obtained through the Yorkshire and Humber Sheffield Research Ethics Committee (reference number: 16/YH/0206). Study results will be published on the study website, in peer-reviewed journals and presented at relevant conferences and via social media.Trial registration numberNCT02598401; Pre-results.


2014 ◽  
Vol 93 (9) ◽  
pp. E34-E36 ◽  
Author(s):  
Michael Yunaev ◽  
Muzib Abdul-Razak ◽  
Hedley Coleman ◽  
Yaroslav Mayorchak ◽  
Ian Kalnins

Ameloblastic carcinoma is a rare type of ameloblastoma that has received little mention in the literature. While a number of cases have been published over many years, no institution has been able to produce a substantial case series. Ameloblastic carcinoma originates in the embryonic tooth components. It is believed to be an aggressive tumor that can metastasize; once metastasis occurs, the prognosis tends to be poor. Ameloblastic carcinoma is primarily a surgical condition that is best treated with resection; there has been little indication that other modalities are helpful. We present the case of a 40-year-old woman who was found to have a mandibular lesion by a dentist. After surgical resection, the tumor was found to be an ameloblastic carcinoma. The patient recovered without complication, and she was recurrence-free 18 months postoperatively. We also briefly review the available literature on the natural history of and management options for this rare tumor.


2014 ◽  
Vol 142 (suppl_1) ◽  
pp. A124-A124
Author(s):  
Binara Assylbekova ◽  
Anneliese Velez Perez ◽  
Andy Nguyen

2009 ◽  
Vol 6 (S2) ◽  
Author(s):  
Claus Mosdal ◽  
Mikkel Mylius Rasmussen ◽  
Dorte Clemmensen
Keyword(s):  

2006 ◽  
pp. 066-071
Author(s):  
Aleksandr Yuryevich Mushkin ◽  
Andrey Aleksandrovich Pershin ◽  
Klarissa Nikolayevna Kovalenko

A report of a rare case of the spinal hydatidosis in a child is presented. Spinal hydatidosis with a total spinal instability caused by the natural history of the disease and inadequate surgical treatment was diagnosed in a 10 year-old girl. At the department the excision of paravertebral and prevertebral hydatid cavernous masses followed by anterior L1–L5 reconstruction and posterior spinal CD-instrumentation was performed. Early post-op results are satisfactory, supporting ability of the spine is restored, that allowed physical and social rehabilitation of the child. Diagnostic pitfalls are identified and discussed.


2021 ◽  
Vol 1 ◽  
pp. 5
Author(s):  
Faham Khamesipour ◽  
Saeed Nezaratizade ◽  
Bahareh Basirpour ◽  
Bahareh Chelgerdi Dehkordi ◽  
Sana Sadat Afzal ◽  
...  

Dirofilariasis is a metazoonoses transmitted by certain mosquito genera (Culicidae: Diptera). Chiefly canids are the reservoirs of Dirofilaria spp. This article analyzed all published records and researches relevant to Dirofilaria in Iran, to provide a basis for future studies in Iran and around the world. All of the important data from human and animal cases that included the pathogen and its reservoir, dispersion, and retrospective studies were investigated and analyzed. Furthermore, the natural history of parasites, pathogenicity, diagnosis, treatment, control, and the final status of the disease in the world was briefly mentioned. Two species of the genus Dirofilaria, Dirofilaria immitis (canine heartworm) and Dirofilaria repens, are detected in Iran. Till now, 13 human cases have been formally reported including seven subcutaneous and three ocular cases of D. repens, a four cases of D. immitis, including a rare case in testicular hydrocele, one ocular and one pre-ocular, a subconjunctival and two pulmonary cases suspected to be D. immitis. Animal and human infections have been recorded in 11 provinces of Iran. Different investigators have reported D. immitis in dogs (with the frequency of 0.95–62.8%), jackals (2.5 57.4%), foxes (5.7–50%), wolves (20–50%), and cats (0.8%) and D. repens in dogs (1.4–60.8%) and jackals (10%) in different areas of the country. The reports on Dirofilaria in Iran are to some extent scattered as regarded to distribution and other features of the disease. More studies should be taken in dirofilariasis in Iran, specifically in regions from where there are no reports.


2010 ◽  
Vol 10 (4) ◽  
pp. 255-259 ◽  
Author(s):  
José Carlos Motta-Junior ◽  
Marco Antonio Monteiro Granzinolli ◽  
Alberto Resende Monteiro

Sixteen opportunistic field observations of eight species of Brazilian raptors (Falconiformes and Strigiformes) are reported here as a contribution to the knowledge of the natural history of these poorly studied birds in Brazil. The observations are related to the food habits (Buteo albicaudatus, Herpetotheres cachinnans, Milvago chimachima, Falco femoralis), reproduction (Asio stygius, Megascops choliba), mobbing behaviour elicited in other birds (Geranospiza caerulescens, H. cachinnans, F. femoralis, A. stygius, Athene cunicularia) and a rare case of leucism in owls (A. cunicularia).


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