scholarly journals High-molecular-weight kininogen and the risk of a myocardial infarction and ischemic stroke in young women: the RATIO case-control study

2012 ◽  
Vol 10 (11) ◽  
pp. 2409-2412 ◽  
Author(s):  
B. SIEGERINK ◽  
F. R. ROSENDAAL ◽  
A. ALGRA
Keyword(s):  
Myocardial Infarction ◽  
Molecular Weight ◽  
Ischemic Stroke ◽  
High Molecular Weight ◽  
Young Women ◽  
Case Control Study ◽  
Case Control ◽  
High Molecular Weight Kininogen ◽  
Control Study ◽  
Stroke In Young

Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study

2009 ◽  
Vol 8 (11) ◽  
pp. 998-1005 ◽  
Author(s):  
Rolf T Urbanus ◽  
Bob Siegerink ◽  
Mark Roest ◽  
Frits R Rosendaal ◽  
Philip G de Groot ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Ischaemic Stroke ◽  
Young Women ◽  
Antiphospholipid Antibodies ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Stroke In Young

scholarly journals Common Variations in Prothrombotic Genes and Susceptibility to Ischemic Stroke in Young Patients: A Case-Control Study in Southeast Iran

Medicina ◽  
2019 ◽  
Vol 55 (2) ◽  
pp. 47
Author(s):  
Seyed Hashemi ◽  
Nourollah Ramroodi ◽  
Hamed Amiri Fard ◽  
Sahar Talebian ◽  
Maryam Haghighi Rohani ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Control Study ◽  
Young Patients ◽  
Mthfr C677t ◽  
Case Control ◽  
Prothrombin G20210a ◽  
Increased Risk ◽  
Objective Evidence ◽  
Control Study ◽  
Stroke In Young

Background and Objective: Evidence indicates that genetic factors may be involved in the risk of ischemic stroke (IS). The aim of this study was to assess the effect of genetic polymorphisms located in exons or untranslated regions of MTHFR as well as FV genes on ischemic stroke. Materials and Methods: In this case-control study, 106 patients with IS and 157 healthy volunteers (age <50 years) were genotyped for MTHFR C677T, A1298C, C2572A and C4869G, FVL, and prothrombin G20210A polymorphisms. Results: The MTHFR 677CT genotype was more frequent in patients and increased risk of IS with Odds Ratio = 1.9. The MTHFR A1298C and C2572A polymorphisms were not associated with IS in dominant and recessive models. Our findings showed a significant decrease in the MTHFR 4869CG genotype in IS patients, and this variant was associated with a decreased risk of IS in the dominant model. The CAAT haplotype was associated with increased risk, and the GAAC haplotype was associated with decreased risk of IS compared to other haplotypes. There was no relation between FVL G1691A polymorphism and IS risk. Conclusions: The present study showed that the MTHFR 677CT genotype was more frequent and the MTHFR 4869CG genotype was less frequent in young IS patients.

scholarly journals Migraine and stroke in young women: case-control study

BMJ ◽  
1999 ◽  
Vol 318 (7175) ◽  
pp. 13-18 ◽  
Author(s):  
C L Chang ◽  
M. Donaghy ◽  
N. Poulter
Keyword(s):  
Young Women ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Stroke In Young

scholarly journals Case-control study of migraine and risk of ischaemic stroke in young women

BMJ ◽  
1995 ◽  
Vol 310 (6983) ◽  
pp. 830-833 ◽  
Author(s):  
C. Tzourio ◽  
A. Tehindrazanarivelo ◽  
S. Iglesias ◽  
A. Alperovitch ◽  
F. Chedru ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Young Women ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Stroke In Young

The Leu33/Pro Polymorphism (PIA1/PIA2 ) of the Glycoprotein IIIa (GPIIIa) Receptor Is Not Related to Myocardial Infarction in the ECTIM Study

1997 ◽  
Vol 77 (06) ◽  
pp. 1179-1181 ◽  
Author(s):  
Stefan-Martin Herrmann ◽  
Odette Poirier ◽  
Pedro Marques-Vidal ◽  
Alun Evans ◽  
Dominique Arveiler ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Receptor Complex ◽  
Genotype Frequencies ◽  
Large Multicenter Study ◽  
Glycoprotein Iiia ◽  
Coronary Syndromes ◽  
Control Study

SummaryThe GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlAl/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls.

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