scholarly journals Kyphectomy for congenital kyphosis due to meningomyelocele: a case treated with a modified approach to skin healing

2011 ◽  
Vol 9 (3) ◽  
pp. 311-315 ◽  
Author(s):  
Kamil Cagri Kose ◽  
Mustafa Erkan Inanmaz ◽  
Mustafa Uslu ◽  
Emre Bal ◽  
Islam Caliskan
Keyword(s):  
Congenital Kyphosis ◽  
Skin Healing

Comparative Characterization of Different Samples Containing Nano-ZnO Particles with Applicability in Topical Therapies

2019 ◽  
Vol 56 (3) ◽  
pp. 652-656
Author(s):  
Raul Chioibas ◽  
Florin Borcan ◽  
Ovidiu Mederle ◽  
Dana Stoian ◽  
Codruta Marinela Soica
Keyword(s):  
Synthesis Method ◽  
Pharmaceutical Preparations ◽  
Ultrasound Treatment ◽  
Heating Process ◽  
White Pigment ◽  
Nano Zno ◽  
Zno Particles ◽  
Repeated Freezing ◽  
Skin Healing

Zinc oxide (ZnO) is an inorganic compound used for its antiseptic and skin healing properties. It is an excellent protective filter against UV radiation and it can be used as white pigment in pharmaceutical preparations. In this study, nano-ZnO particles were obtained by ultrasound treatment, and respectively by repeated freezing/heating process. The influence of synthesis method and of ultrasound generator parameters on the particles size and stability was observed. The results reveal that were obtained samples with a very good stability and sizes between 15 and 96 nm. It was found that synthesis based on ultrasound treatment lead to the formation of nanoparticles with lower sizes.

scholarly journals Genetic Deletion of Galectin-3 Does Not Impair Full-Thickness Excisional Skin Healing

2016 ◽  
Vol 136 (5) ◽  
pp. 1042-1050 ◽  
Author(s):  
John T. Walker ◽  
Christopher G. Elliott ◽  
Thomas L. Forbes ◽  
Douglas W. Hamilton
Keyword(s):  
Full Thickness ◽  
Galectin 3 ◽  
Genetic Deletion ◽  
Skin Healing

scholarly journals A Case of Subacute Cutaneous Lupus Erythematosus in a Patient with Mixed Connective Tissue Disease: Successful Treatment with Plasmapheresis and Rituximab

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
M. Fantò ◽  
S. Salemi ◽  
F. Socciarelli ◽  
A. Bartolazzi ◽  
G. A. Natale ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Lupus Erythematosus ◽  
Mixed Connective Tissue Disease ◽  
High Titer ◽  
Cutaneous Lupus Erythematosus ◽  
Subacute Cutaneous Lupus Erythematosus ◽  
Anti Cd20 ◽  
Skin Healing ◽  
Cutaneous Lupus

A 30-year-old woman affected by Mixed Connective Tissue Disease with scleroderma spectrum developed a facial eruption, a clinical and histological characteristic of subacute cutaneous lupus erythematosus (SCLE). Speckled anti-nuclear antibodies, high-titer anti-ribonucleoprotein1, anti-Sm, anti-Cardiolipin (aCL) IgG/IgM, and anti-Ro/SSA antibodies were positive. SCLE was resistant to Azathioprine, Hydroxychloroquine, and Methotrexate while Mycophenolate Mofetil was suspended due to side effects. Subsequently, the patient was treated with three cycles of therapeutic plasma exchange (TPE) followed, one month after the last TPE, by the anti-CD20 antibody Rituximab (RTX) (375 mg/m2weekly for 4 weeks). Eight and 16 months later the patient received other two TPE and RTX cycles, respectively. This therapeutic approach has allowed to obtain a complete skin healing persistent even after 8-month follow-up. Moreover, mitigation of Raynaud's phenomenon, resolution of alopecia, and a decline of aCL IgG/IgM and anti-Ro/SSA antibodies were observed.

scholarly journals SURGICAL TREATMENT OF CONGENITAL KYPHOSIS IN PATIENTS OLDER THAN 10 YEARS

2016 ◽  
pp. 20-26
Author(s):  
Mikhail Mikhailovsky ◽  
◽  
Vyacheslav Novikov ◽  
Aleksandr Vasyura ◽  
Inga Udalova ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Congenital Kyphosis

scholarly journals EFFECT OF PROBIOTIC ORAL ADMINISTRATION ON SKIN WOUND HEALING IN RATS

2019 ◽  
Vol 32 (3) ◽  
Author(s):  
Eliane TAGLIARI ◽  
Leticia Fuganti CAMPOS ◽  
Antonio Carlos CAMPOS ◽  
Thaís Andrade COSTA-CASAGRANDE ◽  
Lúcia de NORONHA
Keyword(s):  
Oral Administration ◽  
Healing Process ◽  
Control Group ◽  
Type Iii Collagen ◽  
Type I ◽  
Male Adult ◽  
Wound Area ◽  
Probiotic Group ◽  
Inflammatory Phase ◽  
Skin Healing

ABSTRACT Background: Manipulating intestinal microbiota with probiotics might stimulate skin response. Understanding all stages of the healing process, as well as the gut-skin-healing response can improve the skin healing process. Aim: To evaluate the effect of perioperative oral administration of probiotics on the healing of skin wounds in rats. Methods: Seventy-two Wistar male adult rats were weighed and divided into two groups with 36 each, one control group (supplemented with oral maltodextrin 250 mg/day) and one probiotic group (supplemented with Lactobacillus paracasei LPC-37, Bifidobacterium lactis HN0019, Lactobacillus rhamnosus HN001, Lactobacillus acidophilus NCFM® at a dose of 250 mg/day), both given orally daily for 15 days. The two groups were subsequently divided into three subgroups according to the moment of euthanasia: in the 3rd, 7th and 10th postoperative days. Results: There were no significant changes in weight in both groups. Wound contraction was faster in probiotic group when compared to the controls, resulting in smaller wound area in the 7th postoperative day. As for histological aspects, the overall H&E score was lower in the probiotic group. The probiotic group showed increased fibrosis from 3rd to the 7th postoperative day. The type I collagen production was higher in the probiotic group at the 10th postoperative day, and the type III collagen increased in the 7th. Conclusion: The perioperative use of orally administrated probiotic was associated with a faster reduction of the wound area in rats probably by reducing the inflammatory phase, accelerating the fibrosis process and the deposition of collagen.

scholarly journals PROSPECÇÃO TECNOLÓGICA DA HYPTIS PECTINATA NA CICATRIZAÇÃO CUTÂNEA EM ANIMAL / TECHNOLOGICAL PROSPECTION OF THE HYPTIS PECTINATA IN SKIN HEALING IN ANIMALS

2021 ◽  
Vol 7 (1) ◽  
pp. 7324-7340
Author(s):  
Evelynne Hildegard Marques de Melo ◽  
Fernanda Thaís de Vasconcelos Nobre ◽  
Millane Barbosa dos Santos ◽  
Thiago Barros Correia Silva ◽  
Sandra Simone de Barros Lima ◽  
...  
Keyword(s):  
Skin Healing

scholarly journals New Insights on the Effects of Dietary Omega-3 Fatty Acids on Impaired Skin Healing in Diabetes and Chronic Venous Leg Ulcers

Foods ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2306
Author(s):  
Simona Serini ◽  
Gabriella Calviello
Keyword(s):  
Fatty Acids ◽  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Healing Process ◽  
Vascular Diseases ◽  
Lower Limbs ◽  
Bioactive Metabolites ◽  
Omega 3 ◽  
Patients With Diabetes ◽  
Skin Healing

Long-chain Omega-3 polyunsaturated fatty acids (Omega-3 PUFAs) are widely recognized as powerful negative regulators of acute inflammation. However, the precise role exerted by these dietary compounds during the healing process is still largely unknown, and there is increasing interest in understanding their specific effects on the implicated cells/molecular factors. Particular attention is being focused also on their potential clinical application in chronic pathologies characterized by delayed and impaired healing, such as diabetes and vascular diseases in lower limbs. On these bases, we firstly summarized the current knowledge on wound healing (WH) in skin, both in normal conditions and in the setting of these two pathologies, with particular attention to the cellular and molecular mechanisms involved. Then, we critically reviewed the outcomes of recent research papers investigating the activity exerted by Omega-3 PUFAs and their bioactive metabolites in the regulation of WH in patients with diabetes or venous insufficiency and showing chronic recalcitrant ulcers. We especially focused on recent studies investigating the mechanisms through which these compounds may act. Considerations on the optimal dietary doses are also reported, and, finally, possible future perspectives in this area are suggested.

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